Targeting aberrant glutathione metabolism to eradicate human acute myelogenous leukemia cells

Journal of Biological Chemistry

Volumn 288, Issue 47, 2013, Pages 33542-33558

  Pei, Shanshan ^a,c   Minhajuddin, Mohammad ^c   Callahan, Kevin P ^a   Balys, Marlene ^a   Ashton, John M ^a   Neering, Sarah J ^a   Lagadinou, Eleni D ^a   Corbett, Cheryl ^a   Ye, Haobin ^a,c   Liesveld, Jane L ^a   O'Dwyer, Kristen M ^a   Li, Zheng ^d   Shi, Lei ^d   Greninger, Patricia ^e   Settleman, Jeffrey ^e   Benes, Cyril ^e   Hagen, Fred K ^b   Munger, Joshua ^b   Crooks, Peter A ^f   Becker, Michael W ^a   Jordan, Craig T ^a,c   more..

^a UNIVERSITY OF ROCHESTER MEDICAL CENTER   (United States)

^b UNIVERSITY OF ROCHESTER   (United States)

^c UNIVERSITY OF COLORADO SCHOOL OF MEDICINE   (United States)

^d WEILL CORNELL MEDICAL COLLEGE   (United States)

^e HARVARD MEDICAL SCHOOL   (United States)

^f UNIVERSITY OF ARKANSAS AT LITTLE ROCK   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACUTE MYELOGENOUS LEUKEMIA; GLUTATHIONE METABOLISM; GLUTATHIONE PATHWAY; INTRINSIC PROPERTY; LEUKEMIA STEM CELLS; MOLECULAR MECHANISM; REDUCED GLUTATHIONE; REGULATORY PROTEIN;

CELL DEATH; DISEASES; METABOLISM; PHYSIOLOGY; STEM CELLS;

PEPTIDES;

CD34 ANTIGEN; GCLC PROTEIN; GLUTATHIONE; GLUTATHIONE DISULFIDE; PARTHENOLIDE; PIPERLONGUMINE; REGULATOR PROTEIN; UNCLASSIFIED DRUG;

ACUTE GRANULOCYTIC LEUKEMIA; ARTICLE; CANCER STEM CELL; CELL DEATH; CONTROLLED STUDY; ENZYME INHIBITION; GLUTATHIONE METABOLISM; HUMAN; HUMAN CELL; LEUKEMIA CELL; METABOLIC REGULATION; OXIDATION REDUCTION STATE; OXIDATIVE STRESS; PRIORITY JOURNAL;

ANTICANCER DRUG; CANCER STEM CELLS; CD34+; GLUTATHIONE; HUMAN; LEUKEMIA; PARTHENOLIDE; REDOX REGULATION; TUMOR METABOLISM;

ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; ANTIGENS, CD34; DIOXOLANES; FEMALE; GLUTAMATE-CYSTEINE LIGASE; GLUTATHIONE; GLUTATHIONE PEROXIDASE; HUMANS; LEUKEMIA, MYELOID, ACUTE; MALE; OXIDATION-REDUCTION; OXIDATIVE STRESS; SESQUITERPENES; TUMOR CELLS, CULTURED;

EID: 84888362641     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M113.511170     Document Type: Article

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