BCL-2 inhibition targets oxidative phosphorylation and selectively eradicates quiescent human leukemia stem cells

Cell Stem Cell

Volumn 12, Issue 3, 2013, Pages 329-341

  Lagadinou, Eleni D ^a   Sach, Alexander ^a   Callahan, Kevin ^a   Rossi, Randall M ^a   Neering, Sarah J ^a   Minhajuddin, Mohammad ^a   Ashton, John M ^a   Pei, Shanshan ^a   Grose, Valerie ^a   O'Dwyer, Kristen M ^a   Liesveld, Jane L ^a   Brookes, Paul S ^a   Becker, Michael W ^a   Jordan, Craig T ^a  

^a UNIVERSITY OF ROCHESTER MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

PROTEIN BCL 2; PROTEIN INHIBITOR; REACTIVE OXYGEN METABOLITE;

ACUTE GRANULOCYTIC LEUKEMIA; ANIMAL TISSUE; ARTICLE; CELL DEATH; CELL SEPARATION; CONTROLLED STUDY; ENERGY METABOLISM; GLYCOLYSIS; HEMATOLOGIC MALIGNANCY; HUMAN; HUMAN CELL; LEUKEMIA STEM CELL; MITOCHONDRIAL RESPIRATION; MOUSE; NONHUMAN; OXIDATIVE PHOSPHORYLATION; PRIORITY JOURNAL; STEM CELL;

APOPTOSIS; HUMANS; LEUKEMIA, MYELOID, ACUTE; NEOPLASTIC STEM CELLS; OXIDATIVE PHOSPHORYLATION; PROTO-ONCOGENE PROTEINS C-BCL-2; PYRROLES; REACTIVE OXYGEN SPECIES; TUMOR CELLS, CULTURED;

EID: 84875143073     PISSN: 19345909     EISSN: 18759777     Source Type: Journal    
DOI: 10.1016/j.stem.2012.12.013     Document Type: Article

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