-
1
-
-
50149112445
-
Inhibitors of glutamine synthetase and their potential application in medicine
-
L. Berlicki Inhibitors of glutamine synthetase and their potential application in medicine Mini Rev. Med. Chem. 8 2008 869 878
-
(2008)
Mini Rev. Med. Chem.
, vol.8
, pp. 869-878
-
-
Berlicki, L.1
-
2
-
-
84864040884
-
Dysregulation of glucose transport, glycolysis, TCA cycle and glutaminolysis by oncogenes and tumor suppressors in cancer cells
-
J.Q. Chen, and J. Russo Dysregulation of glucose transport, glycolysis, TCA cycle and glutaminolysis by oncogenes and tumor suppressors in cancer cells Biochim. Biophys. Acta 1826 2012 370 384
-
(2012)
Biochim. Biophys. Acta
, vol.1826
, pp. 370-384
-
-
Chen, J.Q.1
Russo, J.2
-
3
-
-
70350449425
-
Resolving the distinct stages in erythroid differentiation based on dynamic changes in membrane protein expression during erythropoiesis
-
K. Chen, J. Liu, S. Heck, J.A. Chasis, X. An, and N. Mohandas Resolving the distinct stages in erythroid differentiation based on dynamic changes in membrane protein expression during erythropoiesis Proc. Natl. Acad. Sci. USA 106 2009 17413 17418
-
(2009)
Proc. Natl. Acad. Sci. USA
, vol.106
, pp. 17413-17418
-
-
Chen, K.1
Liu, J.2
Heck, S.3
Chasis, J.A.4
An, X.5
Mohandas, N.6
-
4
-
-
0029099953
-
Regulation of glutaminase activity and glutamine metabolism
-
N.P. Curthoys, and M. Watford Regulation of glutaminase activity and glutamine metabolism Annu. Rev. Nutr. 15 1995 133 159
-
(1995)
Annu. Rev. Nutr.
, vol.15
, pp. 133-159
-
-
Curthoys, N.P.1
Watford, M.2
-
5
-
-
37449034854
-
Beyond aerobic glycolysis: Transformed cells can engage in glutamine metabolism that exceeds the requirement for protein and nucleotide synthesis
-
R.J. DeBerardinis, A. Mancuso, E. Daikhin, I. Nissim, M. Yudkoff, S. Wehrli, and C.B. Thompson Beyond aerobic glycolysis: transformed cells can engage in glutamine metabolism that exceeds the requirement for protein and nucleotide synthesis Proc. Natl. Acad. Sci. USA 104 2007 19345 19350
-
(2007)
Proc. Natl. Acad. Sci. USA
, vol.104
, pp. 19345-19350
-
-
Deberardinis, R.J.1
Mancuso, A.2
Daikhin, E.3
Nissim, I.4
Yudkoff, M.5
Wehrli, S.6
Thompson, C.B.7
-
6
-
-
84881329062
-
Reductive glutamine metabolism is a function of the α-ketoglutarate to citrate ratio in cells
-
S.M. Fendt, E.L. Bell, M.A. Keibler, B.A. Olenchock, J.R. Mayers, T.M. Wasylenko, N.I. Vokes, L. Guarente, M.G. Vander Heiden, and G. Stephanopoulos Reductive glutamine metabolism is a function of the α-ketoglutarate to citrate ratio in cells Nat. Commun. 4 2013 2236
-
(2013)
Nat. Commun.
, vol.4
, pp. 2236
-
-
Fendt, S.M.1
Bell, E.L.2
Keibler, M.A.3
Olenchock, B.A.4
Mayers, J.R.5
Wasylenko, T.M.6
Vokes, N.I.7
Guarente, L.8
Vander Heiden, M.G.9
Stephanopoulos, G.10
-
7
-
-
23044474905
-
Amino acid transporters ASCT2 and LAT1 in cancer: Partners in crime?
-
B.C. Fuchs, and B.P. Bode Amino acid transporters ASCT2 and LAT1 in cancer: partners in crime? Semin. Cancer Biol. 15 2005 254 266
-
(2005)
Semin. Cancer Biol.
, vol.15
, pp. 254-266
-
-
Fuchs, B.C.1
Bode, B.P.2
-
8
-
-
34547135698
-
ASCT2 silencing regulates mammalian target-of-rapamycin growth and survival signaling in human hepatoma cells
-
B.C. Fuchs, R.E. Finger, M.C. Onan, and B.P. Bode ASCT2 silencing regulates mammalian target-of-rapamycin growth and survival signaling in human hepatoma cells Am. J. Physiol. Cell Physiol. 293 2007 C55 C63
-
(2007)
Am. J. Physiol. Cell Physiol.
, vol.293
-
-
Fuchs, B.C.1
Finger, R.E.2
Onan, M.C.3
Bode, B.P.4
-
9
-
-
80051866908
-
Oncogenic K-Ras decouples glucose and glutamine metabolism to support cancer cell growth
-
D. Gaglio, C.M. Metallo, P.A. Gameiro, K. Hiller, L.S. Danna, C. Balestrieri, L. Alberghina, G. Stephanopoulos, and F. Chiaradonna Oncogenic K-Ras decouples glucose and glutamine metabolism to support cancer cell growth Mol. Syst. Biol. 7 2011 523
-
(2011)
Mol. Syst. Biol.
, vol.7
, pp. 523
-
-
Gaglio, D.1
Metallo, C.M.2
Gameiro, P.A.3
Hiller, K.4
Danna, L.S.5
Balestrieri, C.6
Alberghina, L.7
Stephanopoulos, G.8
Chiaradonna, F.9
-
10
-
-
64749116346
-
C-Myc suppression of miR-23a/b enhances mitochondrial glutaminase expression and glutamine metabolism
-
P. Gao, I. Tchernyshyov, T.C. Chang, Y.S. Lee, K. Kita, T. Ochi, K.I. Zeller, A.M. De Marzo, J.E. Van Eyk, J.T. Mendell, and C.V. Dang c-Myc suppression of miR-23a/b enhances mitochondrial glutaminase expression and glutamine metabolism Nature 458 2009 762 765
-
(2009)
Nature
, vol.458
, pp. 762-765
-
-
Gao, P.1
Tchernyshyov, I.2
Chang, T.C.3
Lee, Y.S.4
Kita, K.5
Ochi, T.6
Zeller, K.I.7
De Marzo, A.M.8
Van Eyk, J.E.9
Mendell, J.T.10
Dang, C.V.11
-
11
-
-
84879142151
-
Isolation and functional characterization of human erythroblasts at distinct stages: Implications for understanding of normal and disordered erythropoiesis in vivo
-
J. Hu, J. Liu, F. Xue, G. Halverson, M. Reid, A. Guo, L. Chen, A. Raza, N. Galili, and J. Jaffray et al. Isolation and functional characterization of human erythroblasts at distinct stages: implications for understanding of normal and disordered erythropoiesis in vivo Blood 121 2013 3246 3253
-
(2013)
Blood
, vol.121
, pp. 3246-3253
-
-
Hu, J.1
Liu, J.2
Xue, F.3
Halverson, G.4
Reid, M.5
Guo, A.6
Chen, L.7
Raza, A.8
Galili, N.9
Jaffray, J.10
-
12
-
-
84868632060
-
A PML-PPAR-δ pathway for fatty acid oxidation regulates hematopoietic stem cell maintenance
-
K. Ito, A. Carracedo, D. Weiss, F. Arai, U. Ala, D.E. Avigan, Z.T. Schafer, R.M. Evans, T. Suda, C.H. Lee, and P.P. Pandolfi A PML-PPAR-δ pathway for fatty acid oxidation regulates hematopoietic stem cell maintenance Nat. Med. 18 2012 1350 1358
-
(2012)
Nat. Med.
, vol.18
, pp. 1350-1358
-
-
Ito, K.1
Carracedo, A.2
Weiss, D.3
Arai, F.4
Ala, U.5
Avigan, D.E.6
Schafer, Z.T.7
Evans, R.M.8
Suda, T.9
Lee, C.H.10
Pandolfi, P.P.11
-
13
-
-
79952259446
-
Coordination of glucose and glutamine utilization by an expanded Myc network
-
M.R. Kaadige, M.G. Elgort, and D.E. Ayer Coordination of glucose and glutamine utilization by an expanded Myc network Transcription 1 2010 36 40
-
(2010)
Transcription
, vol.1
, pp. 36-40
-
-
Kaadige, M.R.1
Elgort, M.G.2
Ayer, D.E.3
-
14
-
-
1242317710
-
The glutamate/neutral amino acid transporter family SLC1: Molecular, physiological and pharmacological aspects
-
Y. Kanai, and M.A. Hediger The glutamate/neutral amino acid transporter family SLC1: molecular, physiological and pharmacological aspects Pflugers Arch. 447 2004 469 479
-
(2004)
Pflugers Arch.
, vol.447
, pp. 469-479
-
-
Kanai, Y.1
Hediger, M.A.2
-
15
-
-
84879116310
-
Metabolic adaptation of neutrophils in cystic fibrosis airways involves distinct shifts in nutrient transporter expression
-
J. Laval, J. Touhami, L.A. Herzenberg, C. Conrad, N. Taylor, J.L. Battini, M. Sitbon, and R. Tirouvanziam Metabolic adaptation of neutrophils in cystic fibrosis airways involves distinct shifts in nutrient transporter expression J Immunol. 190 2013 6043 6050
-
(2013)
J Immunol.
, vol.190
, pp. 6043-6050
-
-
Laval, J.1
Touhami, J.2
Herzenberg, L.A.3
Conrad, C.4
Taylor, N.5
Battini, J.L.6
Sitbon, M.7
Tirouvanziam, R.8
-
16
-
-
84855453655
-
Glucose-independent glutamine metabolism via TCA cycling for proliferation and survival in B cells
-
A. Le, A.N. Lane, M. Hamaker, S. Bose, A. Gouw, J. Barbi, T. Tsukamoto, C.J. Rojas, B.S. Slusher, and H. Zhang et al. Glucose-independent glutamine metabolism via TCA cycling for proliferation and survival in B cells Cell Metab. 15 2012 110 121
-
(2012)
Cell Metab.
, vol.15
, pp. 110-121
-
-
Le, A.1
Lane, A.N.2
Hamaker, M.3
Bose, S.4
Gouw, A.5
Barbi, J.6
Tsukamoto, T.7
Rojas, C.J.8
Slusher, B.S.9
Zhang, H.10
-
17
-
-
0015247088
-
Cytidine triphosphate synthetase. Covalent intermediates and mechanisms of action
-
A. Levitzki, and D.E. Koshland Jr. Cytidine triphosphate synthetase. Covalent intermediates and mechanisms of action Biochemistry 10 1971 3365 3371
-
(1971)
Biochemistry
, vol.10
, pp. 3365-3371
-
-
Levitzki, A.1
Koshland, Jr.D.E.2
-
18
-
-
84861891911
-
Reprogramming of proline and glutamine metabolism contributes to the proliferative and metabolic responses regulated by oncogenic transcription factor c-MYC
-
W. Liu, A. Le, C. Hancock, A.N. Lane, C.V. Dang, T.W. Fan, and J.M. Phang Reprogramming of proline and glutamine metabolism contributes to the proliferative and metabolic responses regulated by oncogenic transcription factor c-MYC Proc. Natl. Acad. Sci. USA 109 2012 8983 8988
-
(2012)
Proc. Natl. Acad. Sci. USA
, vol.109
, pp. 8983-8988
-
-
Liu, W.1
Le, A.2
Hancock, C.3
Lane, A.N.4
Dang, C.V.5
Fan, T.W.6
Phang, J.M.7
-
19
-
-
84857125452
-
Glut1-mediated glucose transport regulates HIV infection
-
S. Loisel-Meyer, L. Swainson, M. Craveiro, L. Oburoglu, C. Mongellaz, C. Costa, M. Martinez, F.L. Cosset, J.L. Battini, and L.A. Herzenberg et al. Glut1-mediated glucose transport regulates HIV infection Proc. Natl. Acad. Sci. USA 109 2012 2549 2554
-
(2012)
Proc. Natl. Acad. Sci. USA
, vol.109
, pp. 2549-2554
-
-
Loisel-Meyer, S.1
Swainson, L.2
Craveiro, M.3
Oburoglu, L.4
Mongellaz, C.5
Costa, C.6
Martinez, M.7
Cosset, F.L.8
Battini, J.L.9
Herzenberg, L.A.10
-
20
-
-
84879766148
-
Pancreatic cancers rely on a novel glutamine metabolism pathway to maintain redox balance
-
C.A. Lyssiotis, J. Son, L.C. Cantley, and A.C. Kimmelman Pancreatic cancers rely on a novel glutamine metabolism pathway to maintain redox balance Cell Cycle 12 2013 1987 1988
-
(2013)
Cell Cycle
, vol.12
, pp. 1987-1988
-
-
Lyssiotis, C.A.1
Son, J.2
Cantley, L.C.3
Kimmelman, A.C.4
-
21
-
-
36749098400
-
Identification of a hierarchy of multipotent hematopoietic progenitors in human cord blood
-
R. Majeti, C.Y. Park, and I.L. Weissman Identification of a hierarchy of multipotent hematopoietic progenitors in human cord blood Cell Stem Cell 1 2007 635 645
-
(2007)
Cell Stem Cell
, vol.1
, pp. 635-645
-
-
Majeti, R.1
Park, C.Y.2
Weissman, I.L.3
-
22
-
-
0345447592
-
The ubiquitous glucose transporter GLUT-1 is a receptor for HTLV
-
N. Manel, F.J. Kim, S. Kinet, N. Taylor, M. Sitbon, and J.L. Battini The ubiquitous glucose transporter GLUT-1 is a receptor for HTLV Cell 115 2003 449 459
-
(2003)
Cell
, vol.115
, pp. 449-459
-
-
Manel, N.1
Kim, F.J.2
Kinet, S.3
Taylor, N.4
Sitbon, M.5
Battini, J.L.6
-
23
-
-
79953172571
-
Cutting edge: Distinct glycolytic and lipid oxidative metabolic programs are essential for effector and regulatory CD4+ T cell subsets
-
R.D. Michalek, V.A. Gerriets, S.R. Jacobs, A.N. Macintyre, N.J. MacIver, E.F. Mason, S.A. Sullivan, A.G. Nichols, and J.C. Rathmell Cutting edge: distinct glycolytic and lipid oxidative metabolic programs are essential for effector and regulatory CD4+ T cell subsets J. Immunol. 186 2011 3299 3303
-
(2011)
J. Immunol.
, vol.186
, pp. 3299-3303
-
-
Michalek, R.D.1
Gerriets, V.A.2
Jacobs, S.R.3
Macintyre, A.N.4
Maciver, N.J.5
Mason, E.F.6
Sullivan, S.A.7
Nichols, A.G.8
Rathmell, J.C.9
-
24
-
-
80053926733
-
Cripto regulates hematopoietic stem cells as a hypoxic-niche-related factor through cell surface receptor GRP78
-
K. Miharada, G. Karlsson, M. Rehn, E. Rörby, K. Siva, J. Cammenga, and S. Karlsson Cripto regulates hematopoietic stem cells as a hypoxic-niche-related factor through cell surface receptor GRP78 Cell Stem Cell 9 2011 330 344
-
(2011)
Cell Stem Cell
, vol.9
, pp. 330-344
-
-
Miharada, K.1
Karlsson, G.2
Rehn, M.3
Rörby, E.4
Siva, K.5
Cammenga, J.6
Karlsson, S.7
-
25
-
-
84876267967
-
Leukemia cells demonstrate a different metabolic perturbation provoked by 2-deoxyglucose
-
H. Miwa, M. Shikami, M. Goto, S. Mizuno, M. Takahashi, N. Tsunekawa-Imai, T. Ishikawa, M. Mizutani, T. Horio, and M. Gotou et al. Leukemia cells demonstrate a different metabolic perturbation provoked by 2-deoxyglucose Oncol. Rep. 29 2013 2053 2057
-
(2013)
Oncol. Rep.
, vol.29
, pp. 2053-2057
-
-
Miwa, H.1
Shikami, M.2
Goto, M.3
Mizuno, S.4
Takahashi, M.5
Tsunekawa-Imai, N.6
Ishikawa, T.7
Mizutani, M.8
Horio, T.9
Gotou, M.10
-
26
-
-
58149386516
-
The Glut1 and Glut4 glucose transporters are differentially expressed during perinatal and postnatal erythropoiesis
-
A. Montel-Hagen, L. Blanc, M. Boyer-Clavel, C. Jacquet, M. Vidal, M. Sitbon, and N. Taylor The Glut1 and Glut4 glucose transporters are differentially expressed during perinatal and postnatal erythropoiesis Blood 112 2008 4729 4738
-
(2008)
Blood
, vol.112
, pp. 4729-4738
-
-
Montel-Hagen, A.1
Blanc, L.2
Boyer-Clavel, M.3
Jacquet, C.4
Vidal, M.5
Sitbon, M.6
Taylor, N.7
-
27
-
-
40849102818
-
Erythrocyte Glut1 triggers dehydroascorbic acid uptake in mammals unable to synthesize vitamin C
-
A. Montel-Hagen, S. Kinet, N. Manel, C. Mongellaz, R. Prohaska, J.L. Battini, J. Delaunay, M. Sitbon, and N. Taylor Erythrocyte Glut1 triggers dehydroascorbic acid uptake in mammals unable to synthesize vitamin C Cell 132 2008 1039 1048
-
(2008)
Cell
, vol.132
, pp. 1039-1048
-
-
Montel-Hagen, A.1
Kinet, S.2
Manel, N.3
Mongellaz, C.4
Prohaska, R.5
Battini, J.L.6
Delaunay, J.7
Sitbon, M.8
Taylor, N.9
-
28
-
-
64249123991
-
Response: Species diversity in GLUT expression and function
-
A. Montel-Hagen, S. Kinet, N. Manel, C. Mongellaz, R. Prohaska, J.L. Battini, J. Delaunay, M. Sitbon, and N. Taylor Response: Species diversity in GLUT expression and function Cell 137 2009 201 202
-
(2009)
Cell
, vol.137
, pp. 201-202
-
-
Montel-Hagen, A.1
Kinet, S.2
Manel, N.3
Mongellaz, C.4
Prohaska, R.5
Battini, J.L.6
Delaunay, J.7
Sitbon, M.8
Taylor, N.9
-
30
-
-
0021248051
-
The pathways of glutamate and glutamine oxidation by tumor cell mitochondria. Role of mitochondrial NAD(P)+-dependent malic enzyme
-
R.W. Moreadith, and A.L. Lehninger The pathways of glutamate and glutamine oxidation by tumor cell mitochondria. Role of mitochondrial NAD(P)+-dependent malic enzyme J. Biol. Chem. 259 1984 6215 6221
-
(1984)
J. Biol. Chem.
, vol.259
, pp. 6215-6221
-
-
Moreadith, R.W.1
Lehninger, A.L.2
-
31
-
-
59049087460
-
Bidirectional transport of amino acids regulates mTOR and autophagy
-
P. Nicklin, P. Bergman, B. Zhang, E. Triantafellow, H. Wang, B. Nyfeler, H. Yang, M. Hild, C. Kung, and C. Wilson et al. Bidirectional transport of amino acids regulates mTOR and autophagy Cell 136 2009 521 534
-
(2009)
Cell
, vol.136
, pp. 521-534
-
-
Nicklin, P.1
Bergman, P.2
Zhang, B.3
Triantafellow, E.4
Wang, H.5
Nyfeler, B.6
Yang, H.7
Hild, M.8
Kung, C.9
Wilson, C.10
-
32
-
-
48249139469
-
Age-dependent changes in uptake and recycling of ascorbic acid in erythrocytes of Beagle dogs
-
E. Ogawa Age-dependent changes in uptake and recycling of ascorbic acid in erythrocytes of Beagle dogs J. Comp. Physiol. B 178 2008 699 704
-
(2008)
J. Comp. Physiol. B
, vol.178
, pp. 699-704
-
-
Ogawa, E.1
-
33
-
-
67650096912
-
Enhancing CD8 T-cell memory by modulating fatty acid metabolism
-
E.L. Pearce, M.C. Walsh, P.J. Cejas, G.M. Harms, H. Shen, L.S. Wang, R.G. Jones, and Y. Choi Enhancing CD8 T-cell memory by modulating fatty acid metabolism Nature 460 2009 103 107
-
(2009)
Nature
, vol.460
, pp. 103-107
-
-
Pearce, E.L.1
Walsh, M.C.2
Cejas, P.J.3
Harms, G.M.4
Shen, H.5
Wang, L.S.6
Jones, R.G.7
Choi, Y.8
-
34
-
-
84895071580
-
Control of glutamine metabolism by the tumor suppressor Rb
-
M.R. Reynolds, A.N. Lane, B. Robertson, S. Kemp, Y. Liu, B.G. Hill, D.C. Dean, and B.F. Clem Control of glutamine metabolism by the tumor suppressor Rb Oncogene 33 2014 556 566
-
(2014)
Oncogene
, vol.33
, pp. 556-566
-
-
Reynolds, M.R.1
Lane, A.N.2
Robertson, B.3
Kemp, S.4
Liu, Y.5
Hill, B.G.6
Dean, D.C.7
Clem, B.F.8
-
35
-
-
79959588949
-
Glucose, not glutamine, is the dominant energy source required for proliferation and survival of head and neck squamous carcinoma cells
-
V.C. Sandulache, T.J. Ow, C.R. Pickering, M.J. Frederick, G. Zhou, I. Fokt, M. Davis-Malesevich, W. Priebe, and J.N. Myers Glucose, not glutamine, is the dominant energy source required for proliferation and survival of head and neck squamous carcinoma cells Cancer 117 2011 2926 2938
-
(2011)
Cancer
, vol.117
, pp. 2926-2938
-
-
Sandulache, V.C.1
Ow, T.J.2
Pickering, C.R.3
Frederick, M.J.4
Zhou, G.5
Fokt, I.6
Davis-Malesevich, M.7
Priebe, W.8
Myers, J.N.9
-
36
-
-
19944433653
-
Succinate links TCA cycle dysfunction to oncogenesis by inhibiting HIF-alpha prolyl hydroxylase
-
M.A. Selak, S.M. Armour, E.D. MacKenzie, H. Boulahbel, D.G. Watson, K.D. Mansfield, Y. Pan, M.C. Simon, C.B. Thompson, and E. Gottlieb Succinate links TCA cycle dysfunction to oncogenesis by inhibiting HIF-alpha prolyl hydroxylase Cancer Cell 7 2005 77 85
-
(2005)
Cancer Cell
, vol.7
, pp. 77-85
-
-
Selak, M.A.1
Armour, S.M.2
Mackenzie, E.D.3
Boulahbel, H.4
Watson, D.G.5
Mansfield, K.D.6
Pan, Y.7
Simon, M.C.8
Thompson, C.B.9
Gottlieb, E.10
-
37
-
-
79960369458
-
HIF1alpha-dependent glycolytic pathway orchestrates a metabolic checkpoint for the differentiation of TH17 and Treg cells
-
L.Z. Shi, R. Wang, G. Huang, P. Vogel, G. Neale, D.R. Green, and H. Chi HIF1alpha-dependent glycolytic pathway orchestrates a metabolic checkpoint for the differentiation of TH17 and Treg cells J. Exp. Med. 208 2011 1367 1376
-
(2011)
J. Exp. Med.
, vol.208
, pp. 1367-1376
-
-
Shi, L.Z.1
Wang, R.2
Huang, G.3
Vogel, P.4
Neale, G.5
Green, D.R.6
Chi, H.7
-
38
-
-
77956205122
-
The distinct metabolic profile of hematopoietic stem cells reflects their location in a hypoxic niche
-
T. Simsek, F. Kocabas, J. Zheng, R.J. Deberardinis, A.I. Mahmoud, E.N. Olson, J.W. Schneider, C.C. Zhang, and H.A. Sadek The distinct metabolic profile of hematopoietic stem cells reflects their location in a hypoxic niche Cell Stem Cell 7 2010 380 390
-
(2010)
Cell Stem Cell
, vol.7
, pp. 380-390
-
-
Simsek, T.1
Kocabas, F.2
Zheng, J.3
Deberardinis, R.J.4
Mahmoud, A.I.5
Olson, E.N.6
Schneider, J.W.7
Zhang, C.C.8
Sadek, H.A.9
-
39
-
-
84876514626
-
Control of amino-acid transport by antigen receptors coordinates the metabolic reprogramming essential for T cell differentiation
-
L.V. Sinclair, J. Rolf, E. Emslie, Y.B. Shi, P.M. Taylor, and D.A. Cantrell Control of amino-acid transport by antigen receptors coordinates the metabolic reprogramming essential for T cell differentiation Nat. Immunol. 14 2013 500 508
-
(2013)
Nat. Immunol.
, vol.14
, pp. 500-508
-
-
Sinclair, L.V.1
Rolf, J.2
Emslie, E.3
Shi, Y.B.4
Taylor, P.M.5
Cantrell, D.A.6
-
40
-
-
0001477074
-
Substrate specificity of brain hexokinase
-
A. Sols, and R.K. Crane Substrate specificity of brain hexokinase J. Biol. Chem. 210 1954 581 595
-
(1954)
J. Biol. Chem.
, vol.210
, pp. 581-595
-
-
Sols, A.1
Crane, R.K.2
-
41
-
-
84875894714
-
Glutamine supports pancreatic cancer growth through a KRAS-regulated metabolic pathway
-
J. Son, C.A. Lyssiotis, H. Ying, X. Wang, S. Hua, M. Ligorio, R.M. Perera, C.R. Ferrone, E. Mullarky, and N. Shyh-Chang et al. Glutamine supports pancreatic cancer growth through a KRAS-regulated metabolic pathway Nature 496 2013 101 105
-
(2013)
Nature
, vol.496
, pp. 101-105
-
-
Son, J.1
Lyssiotis, C.A.2
Ying, H.3
Wang, X.4
Hua, S.5
Ligorio, M.6
Perera, R.M.7
Ferrone, C.R.8
Mullarky, E.9
Shyh-Chang, N.10
-
42
-
-
66749107425
-
Halofuginone inhibits TH17 cell differentiation by activating the amino acid starvation response
-
M.S. Sundrud, S.B. Koralov, M. Feuerer, D.P. Calado, A.E. Kozhaya, A. Rhule-Smith, R.E. Lefebvre, D. Unutmaz, R. Mazitschek, and H. Waldner et al. Halofuginone inhibits TH17 cell differentiation by activating the amino acid starvation response Science 324 2009 1334 1338
-
(2009)
Science
, vol.324
, pp. 1334-1338
-
-
Sundrud, M.S.1
Koralov, S.B.2
Feuerer, M.3
Calado, D.P.4
Kozhaya, A.E.5
Rhule-Smith, A.6
Lefebvre, R.E.7
Unutmaz, D.8
Mazitschek, R.9
Waldner, H.10
-
43
-
-
0020516425
-
2-Deoxyglucose as a substrate for glutathione regeneration in human and ruminant red blood cells
-
M. Suzuki, J.D. O'Dea, T. Suzuki, and N.S. Agar 2-Deoxyglucose as a substrate for glutathione regeneration in human and ruminant red blood cells Comp. Biochem. Physiol. B 75 1983 195 197
-
(1983)
Comp. Biochem. Physiol. B
, vol.75
, pp. 195-197
-
-
Suzuki, M.1
O'Dea, J.D.2
Suzuki, T.3
Agar, N.S.4
-
44
-
-
84872011926
-
Regulation of glycolysis by Pdk functions as a metabolic checkpoint for cell cycle quiescence in hematopoietic stem cells
-
K. Takubo, G. Nagamatsu, C.I. Kobayashi, A. Nakamura-Ishizu, H. Kobayashi, E. Ikeda, N. Goda, Y. Rahimi, R.S. Johnson, and T. Soga et al. Regulation of glycolysis by Pdk functions as a metabolic checkpoint for cell cycle quiescence in hematopoietic stem cells Cell Stem Cell 12 2013 49 61
-
(2013)
Cell Stem Cell
, vol.12
, pp. 49-61
-
-
Takubo, K.1
Nagamatsu, G.2
Kobayashi, C.I.3
Nakamura-Ishizu, A.4
Kobayashi, H.5
Ikeda, E.6
Goda, N.7
Rahimi, Y.8
Johnson, R.S.9
Soga, T.10
-
45
-
-
84876285741
-
Succinate is an inflammatory signal that induces IL-1β through HIF-1α
-
G.M. Tannahill, A.M. Curtis, J. Adamik, E.M. Palsson-McDermott, A.F. McGettrick, G. Goel, C. Frezza, N.J. Bernard, B. Kelly, and N.H. Foley et al. Succinate is an inflammatory signal that induces IL-1β through HIF-1α Nature 496 2013 238 242
-
(2013)
Nature
, vol.496
, pp. 238-242
-
-
Tannahill, G.M.1
Curtis, A.M.2
Adamik, J.3
Palsson-Mcdermott, E.M.4
McGettrick, A.F.5
Goel, G.6
Frezza, C.7
Bernard, N.J.8
Kelly, B.9
Foley, N.H.10
-
46
-
-
84872048038
-
Distinct metabolic flow enables large-scale purification of mouse and human pluripotent stem cell-derived cardiomyocytes
-
S. Tohyama, F. Hattori, M. Sano, T. Hishiki, Y. Nagahata, T. Matsuura, H. Hashimoto, T. Suzuki, H. Yamashita, and Y. Satoh et al. Distinct metabolic flow enables large-scale purification of mouse and human pluripotent stem cell-derived cardiomyocytes Cell Stem Cell 12 2013 127 137
-
(2013)
Cell Stem Cell
, vol.12
, pp. 127-137
-
-
Tohyama, S.1
Hattori, F.2
Sano, M.3
Hishiki, T.4
Nagahata, Y.5
Matsuura, T.6
Hashimoto, H.7
Suzuki, T.8
Yamashita, H.9
Satoh, Y.10
-
47
-
-
84865285455
-
Metabolic switching and fuel choice during T-cell differentiation and memory development
-
G.J. van der Windt, and E.L. Pearce Metabolic switching and fuel choice during T-cell differentiation and memory development Immunol. Rev. 249 2012 27 42
-
(2012)
Immunol. Rev.
, vol.249
, pp. 27-42
-
-
Van Der Windt, G.J.1
Pearce, E.L.2
-
48
-
-
66249108601
-
Understanding the Warburg effect: The metabolic requirements of cell proliferation
-
M.G. Vander Heiden, L.C. Cantley, and C.B. Thompson Understanding the Warburg effect: the metabolic requirements of cell proliferation Science 324 2009 1029 1033
-
(2009)
Science
, vol.324
, pp. 1029-1033
-
-
Vander Heiden, M.G.1
Cantley, L.C.2
Thompson, C.B.3
-
49
-
-
78650181190
-
The hexosamine biosynthetic pathway couples growth factor-induced glutamine uptake to glucose metabolism
-
K.E. Wellen, C. Lu, A. Mancuso, J.M. Lemons, M. Ryczko, J.W. Dennis, J.D. Rabinowitz, H.A. Coller, and C.B. Thompson The hexosamine biosynthetic pathway couples growth factor-induced glutamine uptake to glucose metabolism Genes Dev. 24 2010 2784 2799
-
(2010)
Genes Dev.
, vol.24
, pp. 2784-2799
-
-
Wellen, K.E.1
Lu, C.2
Mancuso, A.3
Lemons, J.M.4
Ryczko, M.5
Dennis, J.W.6
Rabinowitz, J.D.7
Coller, H.A.8
Thompson, C.B.9
-
50
-
-
57749088701
-
Myc regulates a transcriptional program that stimulates mitochondrial glutaminolysis and leads to glutamine addiction
-
D.R. Wise, R.J. DeBerardinis, A. Mancuso, N. Sayed, X.Y. Zhang, H.K. Pfeiffer, I. Nissim, E. Daikhin, M. Yudkoff, S.B. McMahon, and C.B. Thompson Myc regulates a transcriptional program that stimulates mitochondrial glutaminolysis and leads to glutamine addiction Proc. Natl. Acad. Sci. USA 105 2008 18782 18787
-
(2008)
Proc. Natl. Acad. Sci. USA
, vol.105
, pp. 18782-18787
-
-
Wise, D.R.1
Deberardinis, R.J.2
Mancuso, A.3
Sayed, N.4
Zhang, X.Y.5
Pfeiffer, H.K.6
Nissim, I.7
Daikhin, E.8
Yudkoff, M.9
McMahon, S.B.10
Thompson, C.B.11
-
51
-
-
84872037830
-
Metabolic regulation by the mitochondrial phosphatase PTPMT1 is required for hematopoietic stem cell differentiation
-
W.M. Yu, X. Liu, J. Shen, O. Jovanovic, E.E. Pohl, S.L. Gerson, T. Finkel, H.E. Broxmeyer, and C.K. Qu Metabolic regulation by the mitochondrial phosphatase PTPMT1 is required for hematopoietic stem cell differentiation Cell Stem Cell 12 2013 62 74
-
(2013)
Cell Stem Cell
, vol.12
, pp. 62-74
-
-
Yu, W.M.1
Liu, X.2
Shen, J.3
Jovanovic, O.4
Pohl, E.E.5
Gerson, S.L.6
Finkel, T.7
Broxmeyer, H.E.8
Qu, C.K.9
|