-
22
-
-
0034511179
-
Chasing the cancer demon
-
Knudson AG (2000) Chasing the cancer demon. Annu. Rev. Genet. 34, 1-19
-
(2000)
Annu. Rev. Genet.
, vol.34
, pp. 1-19
-
-
Knudson, A.G.1
-
23
-
-
0035902166
-
Cancer genetics
-
Ponder BAJ (2001) Cancer genetics. Nature 411, 336-341
-
(2001)
Nature
, vol.411
, pp. 336-341
-
-
Ponder, B.A.J.1
-
24
-
-
0036427359
-
The cancer genome anatomy project: Online resources to reveal the molecular signatures of cancer
-
Strausberg RL et al (2002) The cancer genome anatomy project: online resources to reveal the molecular signatures of cancer. Cancer Invest. 20, 1038-1050
-
(2002)
Cancer Invest.
, vol.20
, pp. 1038-1050
-
-
Strausberg, R.L.1
-
25
-
-
0037370476
-
The genetics and genomics of cancer
-
Balmain A, Gray J, Ponder B (2003) The genetics and genomics of cancer. Nat. Genet. 33 Suppl. 238-244
-
(2003)
Nat. Genet.
, vol.33
, Issue.SUPPL.
, pp. 238-244
-
-
Balmain, A.1
Gray, J.2
Ponder, B.3
-
27
-
-
1542515338
-
A census of human cancer genes
-
Futreal PA (2004) A census of human cancer genes. Nat. Rev. Cancer 4, 177-183
-
(2004)
Nat. Rev. Cancer
, vol.4
, pp. 177-183
-
-
Futreal, P.A.1
-
28
-
-
0034707047
-
The DNA damage response: Putting checkpoints in perspective
-
Zhou BBS, Elledge SJ (2000) The DNA damage response: putting checkpoints in perspective. Nature 408, 433-439
-
(2000)
Nature
, vol.408
, pp. 433-439
-
-
Zhou, B.B.S.1
Elledge, S.J.2
-
29
-
-
0035902108
-
Genome maintenance mechanisms preventing cancer
-
Hoeijmakers JHJ (2001) Genome maintenance mechanisms preventing cancer. Nature 411, 366-374
-
(2001)
Nature
, vol.411
, pp. 366-374
-
-
Hoeijmakers, J.H.J.1
-
30
-
-
0036480427
-
Double-strand breaks and translocations in cancer
-
Elliott B, Jasin M (2002) Double-strand breaks and translocations in cancer. CMLS 59, 373-385
-
(2002)
CMLS
, vol.59
, pp. 373-385
-
-
Elliott, B.1
Jasin, M.2
-
32
-
-
18444388265
-
Chromosomal aberrations: Formation, identification and distribution
-
Obe G et al (2002) Chromosomal aberrations: formation, identification and distribution. Mutat. Res. 504, 17-36
-
(2002)
Mutat. Res.
, vol.504
, pp. 17-36
-
-
Obe, G.1
-
33
-
-
0345276580
-
Metallothioneins in human tumors and potential roles in carcinogenesis
-
Cherian MG, Jayasurya A, Bay BH (2003) Metallothioneins in human tumors and potential roles in carcinogenesis. Mutat. Res. 533, 201-209
-
(2003)
Mutat. Res.
, vol.533
, pp. 201-209
-
-
Cherian, M.G.1
Jayasurya, A.2
Bay, B.H.3
-
34
-
-
0242331221
-
Mechanisms of human DNA repair: An update
-
Christmann M (2003) Mechanisms of human DNA repair: an update. Toxicology 193, 3-34
-
(2003)
Toxicology
, vol.193
, pp. 3-34
-
-
Christmann, M.1
-
35
-
-
0038799736
-
Oxidative DNA damage: Mechanisms, mutation, and disease
-
Cooke MS, Evans MD, Dizdaroglu M, Lunec J (2003) Oxidative DNA damage: mechanisms, mutation, and disease. FASEB J. 17, 1195-1214
-
(2003)
FASEB J.
, vol.17
, pp. 1195-1214
-
-
Cooke, M.S.1
Evans, M.D.2
Dizdaroglu, M.3
Lunec, J.4
-
37
-
-
0345448169
-
Substrate specificities and excision kinetics of DNA glycosylases involved in baseexcision repair of oxidative DNA damage
-
Dizdaroglu M (2003) Substrate specificities and excision kinetics of DNA glycosylases involved in baseexcision repair of oxidative DNA damage. Mutat Res. 531, 109-126
-
(2003)
Mutat Res.
, vol.531
, pp. 109-126
-
-
Dizdaroglu, M.1
-
38
-
-
0037288474
-
Chromosome instability in cancer: How, when, and why?
-
Gisselson D (2003) Chromosome instability in cancer: how, when, and why? Adv. Cancer Res. 88, 1-29
-
(2003)
Adv. Cancer Res.
, vol.88
, pp. 1-29
-
-
Gisselson, D.1
-
39
-
-
0141890083
-
Hereditary nonpolyposis colorectal cancer and related conditions
-
Lucci-Cordisco E et al (2003) Hereditary nonpolyposis colorectal cancer and related conditions. Am. J. Med. Genet. 122A, 325-334
-
(2003)
Am. J. Med. Genet.
, vol.122 A
, pp. 325-334
-
-
Lucci-Cordisco, E.1
-
40
-
-
0141534462
-
Roles of BRCA1 and BRCA2 in homologous recombination, DNA replication fidelity and the cellular response to ionizing radiation
-
Powell SN, Kachnic LA (2003) Roles of BRCA1 and BRCA2 in homologous recombination, DNA replication fidelity and the cellular response to ionizing radiation. Oncogene 22, 5784-5791
-
(2003)
Oncogene
, vol.22
, pp. 5784-5791
-
-
Powell, S.N.1
Kachnic, L.A.2
-
41
-
-
0042872991
-
Chemistry and biology of DNA repair
-
Scharer OD (2003) Chemistry and biology of DNA repair. Angew. Chem. 42, 2946-2974
-
(2003)
Angew. Chem.
, vol.42
, pp. 2946-2974
-
-
Scharer, O.D.1
-
42
-
-
0037365789
-
ATM and related protein kinases: Safeguarding genome integrity
-
Shiloh Y (2003) ATM and related protein kinases: safeguarding genome integrity. Nat. Rev. Cancer 3, 155-165
-
(2003)
Nat. Rev. Cancer
, vol.3
, pp. 155-165
-
-
Shiloh, Y.1
-
43
-
-
0038345017
-
Cancer drugs, genetic variation and the glutathione-S-transferase gene family
-
Townsend D, Tew K (2003) Cancer drugs, genetic variation and the glutathione-S-transferase gene family. Am. J. Pharmacogenomics 3, 157-172
-
(2003)
Am. J. Pharmacogenomics
, vol.3
, pp. 157-172
-
-
Townsend, D.1
Tew, K.2
-
48
-
-
0034644537
-
Ras and Rho GTPases: A family reunion
-
Bar-Sagi D, Hall A (2000) Ras and Rho GTPases: a family reunion. Cell 103, 227-238
-
(2000)
Cell
, vol.103
, pp. 227-238
-
-
Bar-Sagi, D.1
Hall, A.2
-
49
-
-
0034644539
-
Cell signaling by receptor tyrosine kinases
-
Schlessinger J (2000) Cell signaling by receptor tyrosine kinases. Cell 103, 211-225
-
(2000)
Cell
, vol.103
, pp. 211-225
-
-
Schlessinger, J.1
-
50
-
-
0033729838
-
Control of the eukaryotic cell cycle by MAP kinase signaling pathways
-
Wilkinson MG, Millar JBA (2000) Control of the eukaryotic cell cycle by MAP kinase signaling pathways. FASEB J. 14, 2147-2157
-
(2000)
FASEB J.
, vol.14
, pp. 2147-2157
-
-
Wilkinson, M.G.1
Millar, J.B.A.2
-
51
-
-
0035902180
-
Oncogenic kinase signalling
-
Blume-Jensen P, Hunter T (2001) Oncogenic kinase signalling. Nature 411, 355-365
-
(2001)
Nature
, vol.411
, pp. 355-365
-
-
Blume-Jensen, P.1
Hunter, T.2
-
52
-
-
0034989234
-
The Ras-Raf relationship: An unfinished puzzle
-
Kerkhoff E, Rapp UR (2001) The Ras-Raf relationship: an unfinished puzzle. Adv. Enzyme Regul. 41, 261-267
-
(2001)
Adv. Enzyme Regul.
, vol.41
, pp. 261-267
-
-
Kerkhoff, E.1
Rapp, U.R.2
-
53
-
-
0035954234
-
Amplification of oncogenes revisited: From expression profiling to clinical application
-
Savelyeva L, Schwab M (2001) Amplification of oncogenes revisited: from expression profiling to clinical application. Cancer Lett. 167, 115-123
-
(2001)
Cancer Lett.
, vol.167
, pp. 115-123
-
-
Savelyeva, L.1
Schwab, M.2
-
54
-
-
0036364945
-
Perspectives in studies of human tumor viruses
-
Klein G (2002) Perspectives in studies of human tumor viruses. Front Biosci. 7, d268-274
-
(2002)
Front Biosci.
, vol.7
-
-
Klein, G.1
-
55
-
-
0036781812
-
C-MYC: More that just a matter of life and death
-
Pelengaris S, Khan M, Evan G (2002) c-MYC: more that just a matter of life and death. Nat. Rev. Cancer 2, 764-776
-
(2002)
Nat. Rev. Cancer
, vol.2
, pp. 764-776
-
-
Pelengaris, S.1
Khan, M.2
Evan, G.3
-
56
-
-
0037235453
-
Retroviral insertional mutagenesis: Tagging cancer pathways
-
Mikkers H, Berns A (2003) Retroviral insertional mutagenesis: tagging cancer pathways. Adv. Cancer Res. 88, 53-99
-
(2003)
Adv. Cancer Res.
, vol.88
, pp. 53-99
-
-
Mikkers, H.1
Berns, A.2
-
57
-
-
1642430733
-
Myc pathways provoking cell suicide and cancer
-
Nilson JA, Cleveland JL (2003) Myc pathways provoking cell suicide and cancer. Oncogene 22, 9007-9021
-
(2003)
Oncogene
, vol.22
, pp. 9007-9021
-
-
Nilson, J.A.1
Cleveland, J.L.2
-
58
-
-
0038697566
-
Raf proteins and cancer: B-Raf is identified as a mutational target
-
Mercer KE, Pritchard CA (2003) Raf proteins and cancer: B-Raf is identified as a mutational target. BBA 1653, 25-40
-
(2003)
BBA
, vol.1653
, pp. 25-40
-
-
Mercer, K.E.1
Pritchard, C.A.2
-
60
-
-
0030240944
-
How cancer arises
-
Weinberg RA (1996) How cancer arises. Sci. Am. 275, 62-70
-
(1996)
Sci. Am.
, vol.275
, pp. 62-70
-
-
Weinberg, R.A.1
-
61
-
-
0030932869
-
Gatekeepers and caretakers
-
Kinzler KW, Vogelstein B (1997) Gatekeepers and caretakers. Nature 386, 761-762
-
(1997)
Nature
, vol.386
, pp. 761-762
-
-
Kinzler, K.W.1
Vogelstein, B.2
-
62
-
-
0032517341
-
The p16INK4a/CDKN2A tumor suppressor and its relatives
-
Ruas M, Peters G (1998) The p16INK4a/CDKN2A tumor suppressor and its relatives. BBA 1378, F115-177
-
(1998)
BBA
, vol.1378
-
-
Ruas, M.1
Peters, G.2
-
63
-
-
0034511179
-
Chasing the cancer demon
-
Knudson AG (2000) Chasing the cancer demon. Annu. Rev. Genet. 34, 1-19
-
(2000)
Annu. Rev. Genet.
, vol.34
, pp. 1-19
-
-
Knudson, A.G.1
-
65
-
-
0035902115
-
Proliferation, cell cycle and apoptosis
-
Evan GI, Vousden KH (2001) Proliferation, cell cycle and apoptosis. Nature 411, 342-348
-
(2001)
Nature
, vol.411
, pp. 342-348
-
-
Evan, G.I.1
Vousden, K.H.2
-
66
-
-
0034927749
-
P53 family update: P73 and p63 develop their own identities
-
Irwin MS, Kaelin WG (2001) p53 family update: p73 and p63 develop their own identities. Cell Growth Different. 12, 337-349
-
(2001)
Cell Growth Different
, vol.12
, pp. 337-349
-
-
Irwin, M.S.1
Kaelin, W.G.2
-
67
-
-
0036884829
-
The retinoblastoma tumour suppressor in development and cancer
-
Classon M, Harlow E (2002) The retinoblastoma tumour suppressor in development and cancer. Nat. Rev. Cancer 2, 910-917
-
(2002)
Nat. Rev. Cancer
, vol.2
, pp. 910-917
-
-
Classon, M.1
Harlow, E.2
-
68
-
-
0036884063
-
SV40 and human tumours: Myth, association or causality?
-
Gazdar AF, Butel JS, Carbone M (2002) SV40 and human tumours: myth, association or causality? Nat. Rev. Cancer 2, 957-964
-
(2002)
Nat. Rev. Cancer
, vol.2
, pp. 957-964
-
-
Gazdar, A.F.1
Butel, J.S.2
Carbone, M.3
-
69
-
-
0036273559
-
Activation et modifications post-traductionnelles de p53 après dommage de l'ADN
-
Leblanc V, May P (2002) Activation et modifications post-traductionnelles de p53 après dommage de l'ADN. Med. Sci. 18, 577-584
-
(2002)
Med. Sci.
, vol.18
, pp. 577-584
-
-
Leblanc, V.1
May, P.2
-
70
-
-
0001510491
-
The RB and p53 pathways in cancer
-
Sherr CJ, McCormick F (2002) The RB and p53 pathways in cancer. Cancer Cell 2, 103-112
-
(2002)
Cancer Cell
, vol.2
, pp. 103-112
-
-
Sherr, C.J.1
McCormick, F.2
-
71
-
-
0036386059
-
Retinoblastoma tumor suppressor and genome stability
-
Zheng L, Lee WH (2002) Retinoblastoma tumor suppressor and genome stability. Adv. Cancer Res. 85, 13-50
-
(2002)
Adv. Cancer Res.
, vol.85
, pp. 13-50
-
-
Zheng, L.1
Lee, W.H.2
-
72
-
-
1542353401
-
Control of apoptosis by p53
-
Fridman JS, Lowe SW (2003) Control of apoptosis by p53. Oncogene 22, 9030-9040
-
(2003)
Oncogene
, vol.22
, pp. 9030-9040
-
-
Fridman, J.S.1
Lowe, S.W.2
-
75
-
-
0037309326
-
Tumor suppression by Ink4a-Arf: Progress and puzzles
-
Lowe SW, Sherr CJ (2003) Tumor suppression by Ink4a-Arf: progress and puzzles. Curr. Opin. Genet. Devel. 13, 77-83
-
(2003)
Curr. Opin. Genet. Devel.
, vol.13
, pp. 77-83
-
-
Lowe, S.W.1
Sherr, C.J.2
-
77
-
-
2542432915
-
Haploinsufficiency for tumour suppressor genes: When you don't need to go all the way
-
Santarosa M, Ashworth A (2004) Haploinsufficiency for tumour suppressor genes: when you don't need to go all the way. BBA 1654, 105-122
-
(2004)
BBA
, vol.1654
, pp. 105-122
-
-
Santarosa, M.1
Ashworth, A.2
-
78
-
-
0842346437
-
Principles of tumor suppression
-
Sherr CJ (2004) Principles of tumor suppression. Cell 116, 235-246
-
(2004)
Cell
, vol.116
, pp. 235-246
-
-
Sherr, C.J.1
-
80
-
-
0033895709
-
Wnt signaling and cancer
-
Polakis P (2000) Wnt signaling and cancer. Genes Devel. 14, 1837-1851
-
(2000)
Genes Devel.
, vol.14
, pp. 1837-1851
-
-
Polakis, P.1
-
81
-
-
0035902140
-
The Hedgehog and Wnt signalling pathways in cancer
-
Taipale J, Beachy PA (2001) The Hedgehog and Wnt signalling pathways in cancer. Nature 411, 349-354
-
(2001)
Nature
, vol.411
, pp. 349-354
-
-
Taipale, J.1
Beachy, P.A.2
-
82
-
-
0037204990
-
Signal transduction by the TGF β superfamily
-
Attisano L, Wrana JL (2002) Signal transduction by the TGF β superfamily. Science 296, 1646-1647
-
(2002)
Science
, vol.296
, pp. 1646-1647
-
-
Attisano, L.1
Wrana, J.L.2
-
83
-
-
0037205048
-
The Phosphoinositide 3-Kinase pathway
-
Cantley LC (2002) The Phosphoinositide 3-Kinase pathway. Science 296, 1655-1657
-
(2002)
Science
, vol.296
, pp. 1655-1657
-
-
Cantley, L.C.1
-
84
-
-
0036488589
-
Role of integrins in cell invasion and migration
-
Hood JD, Cheresh DA (2002) Role of integrins in cell invasion and migration. Nat. Rev. Cancer 2, 91-100
-
(2002)
Nat. Rev. Cancer
, vol.2
, pp. 91-100
-
-
Hood, J.D.1
Cheresh, D.A.2
-
85
-
-
0037205002
-
Integrin connections map: To infinity and beyond
-
Martin KH et al (2002) Integrin connections map: to infinity and beyond. Science 296, 1652-1653
-
(2002)
Science
, vol.296
, pp. 1652-1653
-
-
Martin, K.H.1
-
86
-
-
0037023755
-
Signaling networks that link cell proliferation and cell fate
-
Sears RC, Nevins JR (2002) Signaling networks that link cell proliferation and cell fate. JBC 277, 11617-11620
-
(2002)
JBC
, vol.277
, pp. 11617-11620
-
-
Sears, R.C.1
Nevins, J.R.2
-
87
-
-
0036632368
-
The phosphatidylinositol 3-kinase/AKT pathway in human cancer
-
Vivanco I, Sawyers CL (2002) The phosphatidylinositol 3-kinase/AKT pathway in human cancer. Nat. Rev. Cancer 2, 489-501
-
(2002)
Nat. Rev. Cancer
, vol.2
, pp. 489-501
-
-
Vivanco, I.1
Sawyers, C.L.2
-
88
-
-
0142104985
-
Smad-dependent and Smad-independent pathways in TGF-β family signalling
-
Derynck R, Zhang YE (2003) Smad-dependent and Smad-independent pathways in TGF-β family signalling. Nature 425, 577-584
-
(2003)
Nature
, vol.425
, pp. 577-584
-
-
Derynck, R.1
Zhang, Y.E.2
-
89
-
-
0041677606
-
Principles of interleukin (IL)-6-type cytokine signalling and its regulation
-
Heinrich PC et al (2003) Principles of interleukin (IL)-6-type cytokine signalling and its regulation. Biochem. J. 374, 1-20
-
(2003)
Biochem. J.
, vol.374
, pp. 1-20
-
-
Heinrich, P.C.1
-
90
-
-
0037864520
-
Tuberous sclerosis complex (TSC) gene involvement in sporadic tumours
-
Knowles MA, Hornigold N, Pitt E (2003) Tuberous sclerosis complex (TSC) gene involvement in sporadic tumours. Biochem. Soc. Transact. 31, 597-602
-
(2003)
Biochem. Soc. Transact.
, vol.31
, pp. 597-602
-
-
Knowles, M.A.1
Hornigold, N.2
Pitt, E.3
-
91
-
-
0042286558
-
Notch and cancer: Best to avoid the ups and downs
-
Maillard I, Pear WS (2003) Notch and cancer: best to avoid the ups and downs. Cancer Cell 1, 203-205
-
(2003)
Cancer Cell
, vol.1
, pp. 203-205
-
-
Maillard, I.1
Pear, W.S.2
-
92
-
-
0242456129
-
Notch signaling as a therapeutic target in cancer: A new approach to the development of cell fate modifying agents
-
Nickoloff BJ, Osborne BA, Miele L (2003) Notch signaling as a therapeutic target in cancer: a new approach to the development of cell fate modifying agents. Oncogene 22, 6598-6608
-
(2003)
Oncogene
, vol.22
, pp. 6598-6608
-
-
Nickoloff, B.J.1
Osborne, B.A.2
Miele, L.3
-
93
-
-
0037509990
-
Focal adhesion kinase: The first ten years
-
Parsons JT (2003) Focal adhesion kinase: the first ten years. J. Cell Sci. 116, 1409-1416
-
(2003)
J. Cell Sci.
, vol.116
, pp. 1409-1416
-
-
Parsons, J.T.1
-
94
-
-
0041926731
-
Fidelity and spatio-temporal control in MAP kinase (ERKs) signalling
-
Pouysségur J, Lenormand P (2003) Fidelity and spatio-temporal control in MAP kinase (ERKs) signalling. Eur. J. Biochem. 270, 3291-3299
-
(2003)
Eur. J. Biochem.
, vol.270
, pp. 3291-3299
-
-
Pouysségur, J.1
Lenormand, P.2
-
95
-
-
0142259346
-
The role of Notch in tumorigenesis: Oncogene or tumour suppressor
-
Radtke F, Raj K (2003) The role of Notch in tumorigenesis: oncogene or tumour suppressor. Nat. Rev. Cancer 3, 756-767
-
(2003)
Nat. Rev. Cancer
, vol.3
, pp. 756-767
-
-
Radtke, F.1
Raj, K.2
-
96
-
-
0242499448
-
Cytostatic and apoptotic actions of TGF-β in homeostasis and cancer
-
Siegel PM, Massagué J (2003) Cytostatic and apoptotic actions of TGF-β in homeostasis and cancer. Nat Rev Cancer 3:807-820
-
(2003)
Nat Rev Cancer
, vol.3
, pp. 807-820
-
-
Siegel, P.M.1
Massagué, J.2
-
97
-
-
0037309239
-
You Wnt some, you lose some: Oncogenes in the Wnt signaling pathway
-
Van Es, Barker N, Clevers H (2003) You Wnt some, you lose some: oncogenes in the Wnt signaling pathway. Curr. Opin. Genet. Devel. 13, 28-33
-
(2003)
Curr. Opin. Genet. Devel.
, vol.13
, pp. 28-33
-
-
Van, E.S.1
Barker, N.2
Clevers, H.3
-
98
-
-
1542328234
-
The IKK/NF-kappaB activation pathway - A target for prevention and treatment of cancer
-
Greten FR, Karin M (2004) The IKK/NF-kappaB activation pathway - a target for prevention and treatment of cancer. Cancer Lett. 206, 193-199
-
(2004)
Cancer Lett.
, vol.206
, pp. 193-199
-
-
Greten, F.R.1
Karin, M.2
-
99
-
-
1542269303
-
Integrins: Roles in cancer development and as treatment targets
-
Jin H, Varner J (2004) Integrins: roles in cancer development and as treatment targets. Brit. J. Cancer 90, 561-565
-
(2004)
Brit. J. Cancer
, vol.90
, pp. 561-565
-
-
Jin, H.1
Varner, J.2
-
100
-
-
2942738996
-
The hedgehog response network: Sensors, switches and routers
-
Lum L, Beachy PA (2004) The hedgehog response network: sensors, switches and routers. Science 304, 1755-1759
-
(2004)
Science
, vol.304
, pp. 1755-1759
-
-
Lum, L.1
Beachy, P.A.2
-
101
-
-
2342461756
-
To die or not to die: How does p53 decide?
-
Slee EA, O'Connor DJ, Lu X (2004) To die or not to die: how does p53 decide? Oncogene 23, 2809-2818
-
(2004)
Oncogene
, vol.23
, pp. 2809-2818
-
-
Slee, E.A.1
O'Connor, D.J.2
Lu, X.3
-
102
-
-
1042302005
-
The STATs of cancer - New molecular targets come of age
-
Yu H, Jove R (2004) The STATs of cancer - new molecular targets come of age. Nat. Rev. Cancer 4, 97-105
-
(2004)
Nat. Rev. Cancer
, vol.4
, pp. 97-105
-
-
Yu, H.1
Jove, R.2
-
104
-
-
0034912853
-
Caspases: More than just killers?
-
Los M et al (2001) Caspases: more than just killers? Trends Immunol. 22, 31-34
-
(2001)
Trends Immunol.
, vol.22
, pp. 31-34
-
-
Los, M.1
-
105
-
-
0037204948
-
TNF-R1 signaling: A beautiful pathway
-
Chen G, Goeddel DV (2002) TNF-R1 signaling: a beautiful pathway. Science 296, 1634-1635
-
(2002)
Science
, vol.296
, pp. 1634-1635
-
-
Chen, G.1
Goeddel, D.V.2
-
106
-
-
0037204952
-
The Fas signaling pathway: More than a paradigm
-
Wajant H (2002) The Fas signaling pathway: more than a paradigm. Science 296, 1635-1636
-
(2002)
Science
, vol.296
, pp. 1635-1636
-
-
Wajant, H.1
-
107
-
-
0037340380
-
Insights into the mitochondrial signaling pathway: What lessons for chemotherapy?
-
Brenner C, Le Bras M, Kroemer G (2003) Insights into the mitochondrial signaling pathway: what lessons for chemotherapy? J. Clin. Immunol. 23, 73-80
-
(2003)
J. Clin. Immunol.
, vol.23
, pp. 73-80
-
-
Brenner, C.1
Le Bras, M.2
Kroemer, G.3
-
108
-
-
0142117313
-
The Bcl-2 family: Roles in cell survival and oncogenesis
-
Cory S, Huang DC, Adams JM (2003) The Bcl-2 family: roles in cell survival and oncogenesis. Oncogene 22, 8590-8607
-
(2003)
Oncogene
, vol.22
, pp. 8590-8607
-
-
Cory, S.1
Huang, D.C.2
Adams, J.M.3
-
109
-
-
0042386051
-
Telomere dysfunction and the initiation of genomic instability
-
Feldser DM, Hackett JA, Greider CW (2003) Telomere dysfunction and the initiation of genomic instability. Nat. Rev. Cancer 3, 623-627
-
(2003)
Nat. Rev. Cancer
, vol.3
, pp. 623-627
-
-
Feldser, D.M.1
Hackett, J.A.2
Greider, C.W.3
-
110
-
-
1642471831
-
PI3K/Akt and apoptosis: Size matters
-
Franke TF et al (2003) PI3K/Akt and apoptosis: size matters. Oncogene 22, 8983-8998
-
(2003)
Oncogene
, vol.22
, pp. 8983-8998
-
-
Franke, T.F.1
-
111
-
-
0038350026
-
Role of telomeres and telomerase in the pathogenesis of human cancer
-
Hahn WC (2003) Role of telomeres and telomerase in the pathogenesis of human cancer. J. Clin. Oncol. 21, 2034-2043
-
(2003)
J. Clin. Oncol.
, vol.21
, pp. 2034-2043
-
-
Hahn, W.C.1
-
112
-
-
1642553460
-
To be, or not to be: NFkB is the answer - Role of Rel/NFkB in the regulation of apoptosis
-
Kucharczak J et al (2003) To be, or not to be: NFkB is the answer - role of Rel/NFkB in the regulation of apoptosis. Oncogene 22, 8961-8982
-
(2003)
Oncogene
, vol.22
, pp. 8961-8982
-
-
Kucharczak, J.1
-
113
-
-
0642314384
-
Non-apoptotic functions of caspases in cellular proliferation and differentiation
-
Schwerk C, Schulze-Osthoff K (2003) Non-apoptotic functions of caspases in cellular proliferation and differentiation. Biochem Pharmacol. 66, 1453-1458
-
(2003)
Biochem Pharmacol.
, vol.66
, pp. 1453-1458
-
-
Schwerk, C.1
Schulze-Osthoff, K.2
-
114
-
-
1542781659
-
When cells get stressed: An integrative view of cellular senescence
-
Ben-Porath I, Weinberg RA (2004) When cells get stressed: an integrative view of cellular senescence. J. Clin. Invest. 113, 8-13
-
(2004)
J. Clin. Invest.
, vol.113
, pp. 8-13
-
-
Ben-Porath, I.1
Weinberg, R.A.2
-
115
-
-
2342635919
-
Cell death by mitotic catastrophe: A molecular definition
-
Castedo M et al (2004) Cell death by mitotic catastrophe: a molecular definition. Oncogene 23, 2825-2837
-
(2004)
Oncogene
, vol.23
, pp. 2825-2837
-
-
Castedo, M.1
-
116
-
-
2342453921
-
Death receptors in chemotherapy and cancer
-
Debatin KM, Krammer PH (2004) Death receptors in chemotherapy and cancer. Oncogene 23, 2950-2966
-
(2004)
Oncogene
, vol.23
, pp. 2950-2966
-
-
Debatin, K.M.1
Krammer, P.H.2
-
117
-
-
85047689866
-
Telomeres, stem cells, senescence, and cancer
-
Sharpless NE, De Pinho RA (2004) Telomeres, stem cells, senescence, and cancer. J. Clin. Invest. 113, 160-168
-
(2004)
J. Clin. Invest.
, vol.113
, pp. 160-168
-
-
Sharpless, N.E.1
De Pinho, R.A.2
-
120
-
-
0033949401
-
Retinoids in embryonic development
-
Ross SA (2000) Retinoids in embryonic development. Physiol Rev. 80, 1021-1054
-
(2000)
Physiol Rev.
, vol.80
, pp. 1021-1054
-
-
Ross, S.A.1
-
121
-
-
0035962637
-
The Rb/chromatin connection and epigenetic control: Opinion
-
Fereira R (2001) The Rb/chromatin connection and epigenetic control: opinion. Oncogene 20, 3128-3133
-
(2001)
Oncogene
, vol.20
, pp. 3128-3133
-
-
Fereira, R.1
-
122
-
-
0037068353
-
DNA methylation in cancer: Too much, but also too little
-
Ehrlich M (2002) DNA methylation in cancer: too much, but also too little. Oncogene 21, 5400-5413
-
(2002)
Oncogene
, vol.21
, pp. 5400-5413
-
-
Ehrlich, M.1
-
123
-
-
0036383067
-
Chromatin remodeling, histone modifications, and DNA methylation: How does it all fit together
-
Geiman TM, Robertson KD (2002) Chromatin remodeling, histone modifications, and DNA methylation: how does it all fit together. J. Cell. Biochem. 87, 117-125
-
(2002)
J. Cell. Biochem.
, vol.87
, pp. 117-125
-
-
Geiman, T.M.1
Robertson, K.D.2
-
124
-
-
0037150730
-
Polycomb repression: From cellular memory to cellular proliferation and cancer
-
Jacobs JJL, van Lohuizen M (2002) Polycomb repression: from cellular memory to cellular proliferation and cancer. BBA 1602, 151-161
-
(2002)
BBA
, vol.1602
, pp. 151-161
-
-
Jacobs, J.J.L.1
Van Lohuizen, M.2
-
125
-
-
0036527775
-
Histone-deacetylase inhibitors: Novel drugs for the treatment of cancer
-
Johnstone RW (2002) Histone-deacetylase inhibitors: novel drugs for the treatment of cancer. Nat. Rev. Drug Discov. 1, 287-299
-
(2002)
Nat. Rev. Drug Discov.
, vol.1
, pp. 287-299
-
-
Johnstone, R.W.1
-
126
-
-
0036274359
-
The fundamental role of epigenetic events in cancer
-
Jones PA, Baylin SB (2002) The fundamental role of epigenetic events in cancer. Nat. Rev. Genet. 3, 415-428
-
(2002)
Nat. Rev. Genet.
, vol.3
, pp. 415-428
-
-
Jones, P.A.1
Baylin, S.B.2
-
127
-
-
0036733675
-
Chromatin modification and epigenetic reprogramming in mammalian development
-
Li E (2002) Chromatin modification and epigenetic reprogramming in mammalian development. Nat. Rev. Genet. 3, 662-673
-
(2002)
Nat. Rev. Genet.
, vol.3
, pp. 662-673
-
-
Li, E.1
-
128
-
-
0036990102
-
Tumor-stroma interactions directing phenotype and progression of epithelial skin tumor cells
-
Mueller MM, Fusenig NE (2002) Tumor-stroma interactions directing phenotype and progression of epithelial skin tumor cells. Differentiation 70, 486-497
-
(2002)
Differentiation
, vol.70
, pp. 486-497
-
-
Mueller, M.M.1
Fusenig, N.E.2
-
130
-
-
0345017786
-
Transcription factors in liver development, differentiation, and regeneration
-
Costa RH et al (2003) Transcription factors in liver development, differentiation, and regeneration. Hepatology 38, 1331-1347
-
(2003)
Hepatology
, vol.38
, pp. 1331-1347
-
-
Costa, R.H.1
-
131
-
-
0141645511
-
Cancer epigenetics: DNA methylation and chromatin alterations in human cancer
-
Esteller M (2003) Cancer epigenetics: DNA methylation and chromatin alterations in human cancer. Adv. Exp. Med. Biol. 532, 39-49
-
(2003)
Adv. Exp. Med. Biol.
, vol.532
, pp. 39-49
-
-
Esteller, M.1
-
132
-
-
0345357773
-
Gene silencing in cancer in association with promoter hypermethylation
-
Herman JG, Baylin SB (2003) Gene silencing in cancer in association with promoter hypermethylation. NEJM 349, 2042-2054
-
(2003)
NEJM
, vol.349
, pp. 2042-2054
-
-
Herman, J.G.1
Baylin, S.B.2
-
133
-
-
0037372003
-
Epigenetic regulation of gene expression: How the genome integrates intrinsic and environmental signals
-
Jaenisch R, Bird A (2003) Epigenetic regulation of gene expression: how the genome integrates intrinsic and environmental signals. Nat. Genet. 33 Suppl., 245-254
-
(2003)
Nat. Genet.
, vol.33
, Issue.SUPPL.
, pp. 245-254
-
-
Jaenisch, R.1
Bird, A.2
-
134
-
-
0347379799
-
Epigenetic theories of cancer initiation
-
Jaffe LF (2003) Epigenetic theories of cancer initiation. Adv. Cancer Res. 90, 209-230
-
(2003)
Adv. Cancer Res.
, vol.90
, pp. 209-230
-
-
Jaffe, L.F.1
-
135
-
-
0037673984
-
Bmi-1 determines the proliferative capacity of normal and leukaemic stem cells
-
Lessard J, Sauvageau G (2003) Bmi-1 determines the proliferative capacity of normal and leukaemic stem cells. Nature 423, 255-260
-
(2003)
Nature
, vol.423
, pp. 255-260
-
-
Lessard, J.1
Sauvageau, G.2
-
136
-
-
0042933857
-
The cell cycle, chromatin and cancer: Mechanism-based therapeutics come of age
-
McLaughlin F, Finn P, La Thangue NB (2003) The cell cycle, chromatin and cancer: mechanism-based therapeutics come of age. Drug Discov Today 8, 793-802
-
(2003)
Drug Discov Today
, vol.8
, pp. 793-802
-
-
McLaughlin, F.1
Finn, P.2
La Thangue, N.B.3
-
137
-
-
0037235309
-
Epigenetic variability and the evolution of human cancer
-
Ohlsson R et al (2003) Epigenetic variability and the evolution of human cancer. Adv. Cancer Res. 88, 145-168
-
(2003)
Adv. Cancer Res.
, vol.88
, pp. 145-168
-
-
Ohlsson, R.1
-
138
-
-
0141785202
-
Gene repression by Polycomb group protein complexes: A distinct complex for every occasion?
-
Otte AP, Kwaks THJ (2003) Gene repression by Polycomb group protein complexes: a distinct complex for every occasion? Curr. Opin. Genet. Devel. 13, 448-454
-
(2003)
Curr. Opin. Genet. Devel.
, vol.13
, pp. 448-454
-
-
Otte, A.P.1
Kwaks, T.H.J.2
-
139
-
-
0141483064
-
Normal and leukemic hematopoesis: Are leukemias a stem cell disorder or a reacquisition of stem cell characteristics
-
Passaguè E et al (2003) Normal and leukemic hematopoesis: Are leukemias a stem cell disorder or a reacquisition of stem cell characteristics. PNAS USA 100, Suppl.1, 11842-11849
-
(2003)
PNAS USA
, vol.100
, Issue.SUPPL.1
, pp. 11842-11849
-
-
Passaguè, E.1
-
140
-
-
0242348752
-
Histone lysine methylation: A signature for chromatin function
-
Sims III RJ, Nishioka K, Reinberg D (2003) Histone lysine methylation: a signature for chromatin function. Trends Genet. 19, 629-639
-
(2003)
Trends Genet.
, vol.19
, pp. 629-639
-
-
Sims III, R.J.1
Nishioka, K.2
Reinberg, D.3
-
142
-
-
2642531973
-
Epigenetics in human disease and prospects for epigenetic therapy
-
Egger G et al (2004) Epigenetics in human disease and prospects for epigenetic therapy. Nature 429, 457-463
-
(2004)
Nature
, vol.429
, pp. 457-463
-
-
Egger, G.1
-
143
-
-
3843106187
-
GSTP1 CpG island hypermethylation as a molecular biomarker for prostate cancer
-
Nakayama M et al (2004) GSTP1 CpG island hypermethylation as a molecular biomarker for prostate cancer. J. Cell. Biochem. 91, 540-552
-
(2004)
J. Cell. Biochem.
, vol.91
, pp. 540-552
-
-
Nakayama, M.1
-
144
-
-
1042290351
-
The SWI/SNF complex - Chromatin and cancer
-
Roberts CWM, Orkin SH (2004) The SWI/SNF complex - chromatin and cancer. Nat. Rev. Cancer 4, 133-142
-
(2004)
Nat. Rev. Cancer
, vol.4
, pp. 133-142
-
-
Roberts, C.W.M.1
Orkin, S.H.2
-
145
-
-
0034443811
-
Metastasis of cancer: A conceptual history from antiquity to the 1990s
-
Weiss L (2000) Metastasis of cancer: a conceptual history from antiquity to the 1990s. Cancer Metastasis Rev. 19, 193-400
-
(2000)
Cancer Metastasis Rev.
, vol.19
, pp. 193-400
-
-
Weiss, L.1
-
146
-
-
0035819527
-
Development of matrix metalloproteinase inhibitors in cancer therapy
-
Hidalgo M, Eckhardt SG (2001) Development of matrix metalloproteinase inhibitors in cancer therapy. J. Natl. Cancer Inst. 93, 178-193
-
(2001)
J. Natl. Cancer Inst.
, vol.93
, pp. 178-193
-
-
Hidalgo, M.1
Eckhardt, S.G.2
-
147
-
-
0035902141
-
The microenvironment of the tumour-host interface
-
Liotta LA, Kohn EC (2001) The microenvironment of the tumour-host interface. Nature 411, 375-379
-
(2001)
Nature
, vol.411
, pp. 375-379
-
-
Liotta, L.A.1
Kohn, E.C.2
-
148
-
-
0035856010
-
Chemokines and molecular basis of cancer
-
Murphy PM (2001) Chemokines and molecular basis of cancer. NEJM 354, 833-835
-
(2001)
NEJM
, vol.354
, pp. 833-835
-
-
Murphy, P.M.1
-
149
-
-
0036674501
-
Dissemination and growth of cancer cells in metastatic sites
-
Chambers AF, Groom AC, MacDonald IC (2002) Dissemination and growth of cancer cells in metastatic sites. Nat. Rev. Cancer 2, 563-572
-
(2002)
Nat. Rev. Cancer
, vol.2
, pp. 563-572
-
-
Chambers, A.F.1
Groom, A.C.2
MacDonald, I.C.3
-
150
-
-
0037192458
-
Matrix metalloproteinase inhibitors and cancer: Trials and tribulations
-
Coussens LM, Fingleton B, Matrisian LM (2002) Matrix metalloproteinase inhibitors and cancer: trials and tribulations. Science 295, 2387-2392
-
(2002)
Science
, vol.295
, pp. 2387-2392
-
-
Coussens, L.M.1
Fingleton, B.2
Matrisian, L.M.3
-
151
-
-
0036108620
-
Cadherin and Catenin alterations in human cancer
-
Hajra KM, Fearon ER (2002) Cadherin and Catenin alterations in human cancer. Genes Chromosomes Cancer 34, 255-268
-
(2002)
Genes Chromosomes Cancer
, vol.34
, pp. 255-268
-
-
Hajra, K.M.1
Fearon, E.R.2
-
152
-
-
0036359548
-
Hypoxia - A key regulatory factor in tumour growth
-
Harris AL (2002) Hypoxia - a key regulatory factor in tumour growth. Nat. Rev. Cancer 2, 38-47
-
(2002)
Nat. Rev. Cancer
, vol.2
, pp. 38-47
-
-
Harris, A.L.1
-
154
-
-
0037967272
-
Tumorigenesis and the angiogenic switch
-
Bergers G, Benjamin LE (2003) Tumorigenesis and the angiogenic switch. Nat. Rev. Cancer 3, 401-410
-
(2003)
Nat. Rev. Cancer
, vol.3
, pp. 401-410
-
-
Bergers, G.1
Benjamin, L.E.2
-
155
-
-
0345601083
-
MET, metastasis, motility and more
-
Birchmeier C et al (2003) MET, metastasis, motility and more. Nat. Rev. Mol. Cell Biol. 4, 915-925
-
(2003)
Nat. Rev. Mol. Cell Biol.
, vol.4
, pp. 915-925
-
-
Birchmeier, C.1
-
156
-
-
0037904987
-
The integrin-actin connection, an eternal love affair
-
Brakebusch C, Fässler R (2003) The integrin-actin connection, an eternal love affair. EMBO J. 22, 2324-2333
-
(2003)
EMBO J.
, vol.22
, pp. 2324-2333
-
-
Brakebusch, C.1
Fässler, R.2
-
157
-
-
0037926778
-
How tumors make bad blood vessels and stroma
-
Dvorak HF (2003) How tumors make bad blood vessels and stroma. Am. J. Pathol. 162, 1747-1757
-
(2003)
Am. J. Pathol.
, vol.162
, pp. 1747-1757
-
-
Dvorak, H.F.1
-
158
-
-
0038236716
-
The basement membrane matrix in malignancy
-
Engbring JA, Kleinman HK (2003) The basement membrane matrix in malignancy. J. Pathol. 200, 465-470
-
(2003)
J. Pathol.
, vol.200
, pp. 465-470
-
-
Engbring, J.A.1
Kleinman, H.K.2
-
160
-
-
0038049137
-
Tumour-cell invasion and migration: Diversity and escape mechanisms
-
Friedl P, Wolf K (2003) Tumour-cell invasion and migration: diversity and escape mechanisms. Nat. Rev. Cancer 3, 362-374
-
(2003)
Nat. Rev. Cancer
, vol.3
, pp. 362-374
-
-
Friedl, P.1
Wolf, K.2
-
161
-
-
0037362947
-
Metastasis suppression: The evolving role of metastasis suppressor genes for regulating cancer cell growth at the secondary site
-
Kauffman EC et al (2003) Metastasis suppression: the evolving role of metastasis suppressor genes for regulating cancer cell growth at the secondary site. J. Urol. 169, 1122-1133
-
(2003)
J. Urol.
, vol.169
, pp. 1122-1133
-
-
Kauffman, E.C.1
-
162
-
-
0037226593
-
A molecular signature of metastasis in primary tumors
-
Ramaswamy S, Ross KN, Lander ES, Golub TR (2003) A molecular signature of metastasis in primary tumors. Nat. Genet. 33, 49-54
-
(2003)
Nat. Genet.
, vol.33
, pp. 49-54
-
-
Ramaswamy, S.1
Ross, K.N.2
Lander, E.S.3
Golub, T.R.4
-
163
-
-
0037279517
-
The hypoxic tumour microenvironment and metastatic progression
-
Subarsky P, Hill RP (2003) The hypoxic tumour microenvironment and metastatic progression. Clin. Exp. Metastasis 20, 237-250
-
(2003)
Clin. Exp. Metastasis
, vol.20
, pp. 237-250
-
-
Subarsky, P.1
Hill, R.P.2
-
164
-
-
3042822267
-
Cancer and the chemokine network
-
Balkwill F (2004) Cancer and the chemokine network. Nat. Rev. Cancer 4, 540-550
-
(2004)
Nat. Rev. Cancer
, vol.4
, pp. 540-550
-
-
Balkwill, F.1
-
165
-
-
1042267263
-
Cell adhesion and signalling by cadherins and Ig-CAMs in cancer
-
Cavallaro U, Christofori G (2004) Cell adhesion and signalling by cadherins and Ig-CAMs in cancer. Nat. Rev. Cancer 4, 118-132
-
(2004)
Nat. Rev. Cancer
, vol.4
, pp. 118-132
-
-
Cavallaro, U.1
Christofori, G.2
-
167
-
-
0033561797
-
Deconstructing a disease: RARα, its fusion partners, and their roles in the pathogenesis of APL
-
Melnick A, Licht JD (1999) Deconstructing a disease: RARα, its fusion partners, and their roles in the pathogenesis of APL. Blood 93, 3167-3215
-
(1999)
Blood
, vol.93
, pp. 3167-3215
-
-
Melnick, A.1
Licht, J.D.2
-
168
-
-
0033565561
-
The biology of CML
-
Faderl S et al (1999) The biology of CML. NEJM 341, 164-172
-
(1999)
NEJM
, vol.341
, pp. 164-172
-
-
Faderl, S.1
-
169
-
-
0034670036
-
The molecular biology of chronic myeloid leukemia
-
Deininger MW, Goldman JM, Melo JV (2000) The molecular biology of chronic myeloid leukemia. Blood 96, 3343-3356
-
(2000)
Blood
, vol.96
, pp. 3343-3356
-
-
Deininger, M.W.1
Goldman, J.M.2
Melo, J.V.3
-
170
-
-
0034327890
-
Molecular biology of Burkitt's lymphoma
-
Hecht JL, Aster JC (2000) Molecular biology of Burkitt's lymphoma. J. Clin Oncol. 18, 3707-3721
-
(2000)
J. Clin Oncol.
, vol.18
, pp. 3707-3721
-
-
Hecht, J.L.1
Aster, J.C.2
-
171
-
-
0036799298
-
Spotlight on APL: Controversies and challenges
-
1893ff editorial
-
Melnick A (2002) Spotlight on APL: controversies and challenges. Leukemia 16, 1893ff (editorial, see also following articles)
-
(2002)
Leukemia
, vol.16
-
-
Melnick, A.1
-
172
-
-
0037169341
-
The role of PML in tumor suppression
-
Salomoni P, Pandolfi PP (2002) The role of PML in tumor suppression. Cell 108, 165-170
-
(2002)
Cell
, vol.108
, pp. 165-170
-
-
Salomoni, P.1
Pandolfi, P.P.2
-
173
-
-
0036050013
-
CML: Mechanisms underlying disease progression
-
Shet AS et al (2002) CML: Mechanisms underlying disease progression. Leukemia 16, 1402-1411
-
(2002)
Leukemia
, vol.16
, pp. 1402-1411
-
-
Shet, A.S.1
-
174
-
-
0037409182
-
The molecular pathogenesis of acute promyelocytic leukemia: Implications for the clinical management of the disease
-
Mistry AR et al (2003) The molecular pathogenesis of acute promyelocytic leukemia: implications for the clinical management of the disease. Blood Rev. 17, 71-97
-
(2003)
Blood Rev.
, vol.17
, pp. 71-97
-
-
Mistry, A.R.1
-
175
-
-
0141483064
-
Normal and leukemic hematopoesis: Are leukemias a stem cell disorder or a reacquisition of stem cell characteristics
-
Passaguè E et al (2003) Normal and leukemic hematopoesis: Are leukemias a stem cell disorder or a reacquisition of stem cell characteristics. PNAS USA 100, Suppl.1, 11842-11849
-
(2003)
PNAS USA
, vol.100
, Issue.SUPPL.1
, pp. 11842-11849
-
-
Passaguè, E.1
-
176
-
-
0141725596
-
Retinoid target genes in acute promyelocytic leukemia
-
Pitha-Rowe I et al (2003) Retinoid target genes in acute promyelocytic leukemia. Leukemia 17, 1723-1730
-
(2003)
Leukemia
, vol.17
, pp. 1723-1730
-
-
Pitha-Rowe, I.1
-
177
-
-
0037315894
-
Disruption of differentiation in human cancer: AML shows the way
-
Tenen TG (2003) Disruption of differentiation in human cancer: AML shows the way. Nat. Rev. Cancer 3, 89-101
-
(2003)
Nat. Rev. Cancer
, vol.3
, pp. 89-101
-
-
Tenen, T.G.1
-
179
-
-
0035835816
-
Wilms tumor and the WT1 gene
-
Lee SB, Haber DA (2001) Wilms tumor and the WT1 gene. Exp. Cell Res. 264, 74-99
-
(2001)
Exp. Cell Res.
, vol.264
, pp. 74-99
-
-
Lee, S.B.1
Haber, D.A.2
-
180
-
-
0034584526
-
Wilms' tumor: A paradigm for the new genetics
-
Malik K et al (2001) Wilms' tumor: a paradigm for the new genetics. Oncol. Res. 12, 441-449
-
(2001)
Oncol. Res.
, vol.12
, pp. 441-449
-
-
Malik, K.1
-
183
-
-
0037501301
-
Two molecular subgroups of Wilms' tumors with or without WT1 mutations
-
Schumacher V et al (2003) Two molecular subgroups of Wilms' tumors with or without WT1 mutations. Clin. Cancer Res. 9, 2005-2014
-
(2003)
Clin. Cancer Res.
, vol.9
, pp. 2005-2014
-
-
Schumacher, V.1
-
184
-
-
2342418469
-
Branching morphogenesis and kidney disease
-
Shah MM et al (2004) Branching morphogenesis and kidney disease. Development 131, 1449-1462
-
(2004)
Development
, vol.131
, pp. 1449-1462
-
-
Shah, M.M.1
-
186
-
-
0035902140
-
The Hedgehog and Wnt signalling pathways in cancer
-
Taipale J, Beachy PA (2001) The Hedgehog and Wnt signalling pathways in cancer. Nature 411, 349-354
-
(2001)
Nature
, vol.411
, pp. 349-354
-
-
Taipale, J.1
Beachy, P.A.2
-
187
-
-
0036245242
-
Getting under the skin of epidermal morphogenesis
-
Fuchs E, Raghavan S (2002) Getting under the skin of epidermal morphogenesis. Nat. Rev. Genet. 3, 199-209
-
(2002)
Nat. Rev. Genet.
, vol.3
, pp. 199-209
-
-
Fuchs, E.1
Raghavan, S.2
-
188
-
-
0036559186
-
Gli and Hedgehog in cancers: Tumours, embryos and stem cells
-
Ruiz i Altaba, Sánchez P, Dahmane N (2002) Gli and Hedgehog in cancers: tumours, embryos and stem cells. Nat. Rev. Cancer 2, 342-350
-
(2002)
Nat. Rev. Cancer
, vol.2
, pp. 342-350
-
-
Altaba, R.I.1
Sánchez, P.2
Dahmane, N.3
-
189
-
-
0037037787
-
Tumor suppressor genes on chromosome 3p involved in the pathogenesis of lung and other cancers
-
Zabarovsky ER, Lerman MI, Minna JD (2002) Tumor suppressor genes on chromosome 3p involved in the pathogenesis of lung and other cancers. Oncogene 21, 6915-6935
-
(2002)
Oncogene
, vol.21
, pp. 6915-6935
-
-
Zabarovsky, E.R.1
Lerman, M.I.2
Minna, J.D.3
-
190
-
-
0141706431
-
Stem cells of the skin epithelium
-
Alonso L, Fuchs E (2003) Stem cells of the skin epithelium. PNAS USA 100 Suppl 1., 11830-11835
-
(2003)
PNAS USA
, vol.100
, Issue.SUPPL. 1
, pp. 11830-11835
-
-
Alonso, L.1
Fuchs, E.2
-
191
-
-
0038456527
-
Understanding the progression of melanocytic neoplasia using genomic analysis: From fields to cancer
-
Bastian BC (2003) Understanding the progression of melanocytic neoplasia using genomic analysis: from fields to cancer. Oncogene 22, 3081-3086
-
(2003)
Oncogene
, vol.22
, pp. 3081-3086
-
-
Bastian, B.C.1
-
192
-
-
0038122762
-
Genetic epidemiology of melanoma
-
Bataille V (2003) Genetic epidemiology of melanoma. Eur. J. Cancer. 39, 1341-1347
-
(2003)
Eur. J. Cancer.
, vol.39
, pp. 1341-1347
-
-
Bataille, V.1
-
193
-
-
0042887050
-
The genetics of malignant melanoma: Lessons from mouse and man
-
Chin L (2003) The genetics of malignant melanoma: lessons from mouse and man. Nat. Rev. Cancer 3, 559-570
-
(2003)
Nat. Rev. Cancer
, vol.3
, pp. 559-570
-
-
Chin, L.1
-
194
-
-
0037217819
-
TP53 mutations in human skin cancers
-
Giglia-Mari G, Sarasin A (2003) TP53 mutations in human skin cancers. Hum. Mutat. 21, 217-228
-
(2003)
Hum. Mutat.
, vol.21
, pp. 217-228
-
-
Giglia-Mari, G.1
Sarasin, A.2
-
195
-
-
0037286724
-
Xeroderma pigmentosum
-
Norgauer J et al (2003) Xeroderma pigmentosum. Eur. J. Dermatol. 13, 4-9
-
(2003)
Eur. J. Dermatol.
, vol.13
, pp. 4-9
-
-
Norgauer, J.1
-
197
-
-
0346816585
-
Epitheliale Hauttumoren: Molekularbiologie und Pathogenesebasierende Therapie
-
Reifenberger J, Schön MP (2003) Epitheliale Hauttumoren: Molekularbiologie und Pathogenesebasierende Therapie. Hautarzt 54, 1164-1170
-
(2003)
Hautarzt
, vol.54
, pp. 1164-1170
-
-
Reifenberger, J.1
Schön, M.P.2
-
198
-
-
1842862755
-
TP53 mutation spectra and load: A tool for generating hypotheses on the etiology of cancer
-
Olivier M et al (2004) TP53 mutation spectra and load: a tool for generating hypotheses on the etiology of cancer. IARC Sci Publ. 157, 247-270
-
(2004)
IARC Sci Publ.
, vol.157
, pp. 247-270
-
-
Olivier, M.1
-
199
-
-
0030592517
-
Lessons from hereditary colorectal cancer
-
Kinzler KW, Vogelstein B (1996) Lessons from hereditary colorectal cancer. Cell 87, 159-170
-
(1996)
Cell
, vol.87
, pp. 159-170
-
-
Kinzler, K.W.1
Vogelstein, B.2
-
200
-
-
0035496616
-
Colorectal cancer prevention and treatment by inhibition of cyclooxygenase-2
-
Gupta RA, Du Bois R (2001) Colorectal cancer prevention and treatment by inhibition of cyclooxygenase-2. Nat. Rev. Cancer 1, 11-21
-
(2001)
Nat. Rev. Cancer
, vol.1
, pp. 11-21
-
-
Gupta, R.A.1
Du Bois, R.2
-
201
-
-
0035956878
-
Mechanisms underlying losses of heterozygosity in human colorectal cancers
-
Thiagalingam S et al (2001) Mechanisms underlying losses of heterozygosity in human colorectal cancers. PNAS USA 98, 2698-2702
-
(2001)
PNAS USA
, vol.98
, pp. 2698-2702
-
-
Thiagalingam, S.1
-
203
-
-
18644373146
-
The β-Catenin/TCF-4 complex imposes a crypt progenitor phenotype on colorectal cancer cells
-
Van de Wetering M et al (2002) The β-Catenin/TCF-4 complex imposes a crypt progenitor phenotype on colorectal cancer cells. Cell 111, 241-250
-
(2002)
Cell
, vol.111
, pp. 241-250
-
-
Van De Wetering, M.1
-
204
-
-
0036081685
-
Novel approaches for colon cancer prevention by cyclooxygenase-2 inhibitors
-
Reddy BS, Rao CV (2002) Novel approaches for colon cancer prevention by cyclooxygenase-2 inhibitors. J. Environ. Pathol. Toxicol. Oncol. 21, 155-164
-
(2002)
J. Environ. Pathol. Toxicol. Oncol.
, vol.21
, pp. 155-164
-
-
Reddy, B.S.1
Rao, C.V.2
-
205
-
-
0038359353
-
Caught up in a Wnt storm: Wnt signaling in cancer
-
Giles RH, van Es JH, Clevers H (2003) Caught up in a Wnt storm: Wnt signaling in cancer. BBA 1653, 1-24
-
(2003)
BBA
, vol.1653
, pp. 1-24
-
-
Giles, R.H.1
Van Es, J.H.2
Clevers, H.3
-
207
-
-
0141890083
-
Hereditary nonpolyposis colorectal cancer and related conditions
-
Lucci-Cordisco E et al (2003) Hereditary nonpolyposis colorectal cancer and related conditions. Am. J. Med. Genet. 122A, 325-334
-
(2003)
Am. J. Med. Genet.
, vol.122 A
, pp. 325-334
-
-
Lucci-Cordisco, E.1
-
208
-
-
0037778008
-
The Wnt signaling pathway and its role in tumor development
-
Lustig B, Behrens J (2003) The Wnt signaling pathway and its role in tumor development. J. Cancer Res. Clin. Oncol. 129, 199-221
-
(2003)
J. Cancer Res. Clin. Oncol.
, vol.129
, pp. 199-221
-
-
Lustig, B.1
Behrens, J.2
-
209
-
-
1242292420
-
Genomic instability and colon cancer
-
Grady WM (2004) Genomic instability and colon cancer. Cancer Metast. Rev. 23, 11-27
-
(2004)
Cancer Metast. Rev.
, vol.23
, pp. 11-27
-
-
Grady, W.M.1
-
210
-
-
3042788940
-
COX-2 inhibition and colorectal cancer
-
Koehne CH, Dubois RN (2004) COX-2 inhibition and colorectal cancer. Semin. Oncol. 31 Suppl. 7, 12-21
-
(2004)
Semin. Oncol.
, vol.31
, Issue.SUPPL. 7
, pp. 12-21
-
-
Koehne, C.H.1
Dubois, R.N.2
-
211
-
-
1542347695
-
Convergence of Wnt, beta-catenin, and cadherin pathways
-
Nelson WJ, Nusse R (2004) Convergence of Wnt, beta-catenin, and cadherin pathways. Science 303, 1483-1487
-
(2004)
Science
, vol.303
, pp. 1483-1487
-
-
Nelson, W.J.1
Nusse, R.2
-
216
-
-
0034902711
-
What we could do now: Molecular pathology of bladder cancer
-
Knowles MA (2001) What we could do now: molecular pathology of bladder cancer. Mol Pathol. 54, 215-221
-
(2001)
Mol Pathol.
, vol.54
, pp. 215-221
-
-
Knowles, M.A.1
-
217
-
-
0037201542
-
Molecular genetics and function of NAT1 and NAT2: Role in aromatic amine metabolism and carcinogenesis
-
Hein DW (2002) Molecular genetics and function of NAT1 and NAT2: role in aromatic amine metabolism and carcinogenesis. Mutat. Res. 506, 65-77
-
(2002)
Mutat. Res.
, vol.506
, pp. 65-77
-
-
Hein, D.W.1
-
218
-
-
0036272911
-
P53 gene mutations: Case study of a clinical marker for solid tumors
-
Liu MC, Gelmann EP (2002) P53 gene mutations: case study of a clinical marker for solid tumors. Semin. Oncol. 29, 246-257
-
(2002)
Semin. Oncol.
, vol.29
, pp. 246-257
-
-
Liu, M.C.1
Gelmann, E.P.2
-
219
-
-
10744222289
-
FGFR3 and TP53 gene mutations define two distinct pathways in urothelial cell carcinoma of the bladder
-
Bakkar AA et al (2003) FGFR3 and TP53 gene mutations define two distinct pathways in urothelial cell carcinoma of the bladder. Cancer Res. 63, 8108-8112
-
(2003)
Cancer Res.
, vol.63
, pp. 8108-8112
-
-
Bakkar, A.A.1
-
220
-
-
0038509103
-
Perspektiven der molekularen Diagnostik am Beispiel des Harnblasenkarzinoms
-
Grimm MO, Burchardt M, Schulz WA (2003) Perspektiven der molekularen Diagnostik am Beispiel des Harnblasenkarzinoms. Urologe 42, 650-659
-
(2003)
Urologe
, vol.42
, pp. 650-659
-
-
Grimm, M.O.1
Burchardt, M.2
Schulz, W.A.3
-
221
-
-
0038493552
-
Molecular prognostication in bladder cancer: A current perspective
-
Quek ML et al (2003) Molecular prognostication in bladder cancer: a current perspective. Eur. J. Cancer 39, 1501-1510
-
(2003)
Eur. J. Cancer
, vol.39
, pp. 1501-1510
-
-
Quek, M.L.1
-
222
-
-
0037772635
-
Markers of genetic susceptibility in human environmental hygiene and toxicology: The role of selected CYP, NAT and GST genes
-
Thier R et al (2003) Markers of genetic susceptibility in human environmental hygiene and toxicology: the role of selected CYP, NAT and GST genes. Int. J. Hyg. Environ. Health 206, 149-171
-
(2003)
Int. J. Hyg. Environ. Health
, vol.206
, pp. 149-171
-
-
Thier, R.1
-
223
-
-
1542405934
-
FGFR3 and P53 characterize alternative genetic pathways in the pathogenesis of urothelial cell carcinoma
-
van Rhijn BW et al (2004) FGFR3 and P53 characterize alternative genetic pathways in the pathogenesis of urothelial cell carcinoma. Cancer Res. 64, 1911-1914
-
(2004)
Cancer Res.
, vol.64
, pp. 1911-1914
-
-
Van Rhijn, B.W.1
-
225
-
-
0031255567
-
The Heidelberg classification of renal cell tumours
-
Kovacs G et al (1997) The Heidelberg classification of renal cell tumours. J. Pathol. 183, 131-133
-
(1997)
J. Pathol.
, vol.183
, pp. 131-133
-
-
Kovacs, G.1
-
226
-
-
0032834658
-
Mechanisms of epithelial development and neoplasia in the metanephric kidney
-
Davies JA, Perera AD, Walker CL (1999) Mechanisms of epithelial development and neoplasia in the metanephric kidney. Int. J. Dev. Biol. 43, 473-478
-
(1999)
Int. J. Dev. Biol.
, vol.43
, pp. 473-478
-
-
Davies, J.A.1
Perera, A.D.2
Walker, C.L.3
-
227
-
-
0035054565
-
Genotype-phenotype correlation in von Hippel-Lindau syndrome
-
Friedrich CA. (2001) Genotype-phenotype correlation in von Hippel-Lindau syndrome. Hum. Mol. Genet. 10, 763-767
-
(2001)
Hum. Mol. Genet.
, vol.10
, pp. 763-767
-
-
Friedrich, C.A.1
-
228
-
-
0035753424
-
FRA3B and other common fragile sites: The weakest links?
-
Huebner K, Croce CM (2001) FRA3B and other common fragile sites: the weakest links? Nat. Rev. Cancer 1, 214-221
-
(2001)
Nat. Rev. Cancer
, vol.1
, pp. 214-221
-
-
Huebner, K.1
Croce, C.M.2
-
229
-
-
0037202189
-
Renal cancer: Cytogenetic and molecular genetic aspects
-
Meloni-Ehrig AM (2002) Renal cancer: cytogenetic and molecular genetic aspects. Am. J. Med. Genet. 115, 164-172
-
(2002)
Am. J. Med. Genet.
, vol.115
, pp. 164-172
-
-
Meloni-Ehrig, A.M.1
-
230
-
-
0036799546
-
Understanding familial and non-familial renal cell cancer
-
Bodmer D et al (2002) Understanding familial and non-familial renal cell cancer. Hum. Mol. Genet. 11, 2489-2498
-
(2002)
Hum. Mol. Genet.
, vol.11
, pp. 2489-2498
-
-
Bodmer, D.1
-
231
-
-
18144437085
-
Genetically determined differences in P-glycoprotein function: Implications for disease risk
-
Fromm MF (2002) Genetically determined differences in P-glycoprotein function: implications for disease risk. Toxicology 181-182, 299-303
-
(2002)
Toxicology
, vol.181-182
, pp. 299-303
-
-
Fromm, M.F.1
-
232
-
-
0036718539
-
Molecular basis of the VHL hereditary cancer syndrome
-
Kaelin WG (2002) Molecular basis of the VHL hereditary cancer syndrome. Nat. Rev. Cancer 2, 673-682
-
(2002)
Nat. Rev. Cancer
, vol.2
, pp. 673-682
-
-
Kaelin, W.G.1
-
233
-
-
0036339479
-
Methylation of the RASSF1A gene in human cancers
-
Pfeifer GP et al (2002) Methylation of the RASSF1A gene in human cancers. Biol. Chem. 383, 907-914
-
(2002)
Biol. Chem.
, vol.383
, pp. 907-914
-
-
Pfeifer, G.P.1
-
234
-
-
0344825356
-
P-glycoprotein: From genomics to mechanism
-
Ambudkar SV et al (2003) P-glycoprotein: from genomics to mechanism. Oncogene 22, 7468-7485
-
(2003)
Oncogene
, vol.22
, pp. 7468-7485
-
-
Ambudkar, S.V.1
-
235
-
-
0042320457
-
Cytokine-based therapy for metastatic renal cell cancer
-
Gitlitz BJ, Figlin RA (2003) Cytokine-based therapy for metastatic renal cell cancer. Urol. Clin. North Am. 30, 589-600
-
(2003)
Urol. Clin. North Am.
, vol.30
, pp. 589-600
-
-
Gitlitz, B.J.1
Figlin, R.A.2
-
236
-
-
0037362890
-
HIF hydroxylation and the mammalian oxygen-sensing pathway
-
Safran M, Kaelin WG (2003) HIF hydroxylation and the mammalian oxygen-sensing pathway. J. Clin. Invest. 111, 779-783
-
(2003)
J. Clin. Invest.
, vol.111
, pp. 779-783
-
-
Safran, M.1
Kaelin, W.G.2
-
237
-
-
0242608613
-
The genetic basis of cancer of the kidney
-
Linehan WM, Walther MM, Zbar B (2003) The genetic basis of cancer of the kidney. J. Urol. 170, 2163-2172
-
(2003)
J. Urol.
, vol.170
, pp. 2163-2172
-
-
Linehan, W.M.1
Walther, M.M.2
Zbar, B.3
-
239
-
-
0038037735
-
Regulation of angiogenesis by hypoxia: Role of the HIF system
-
Pugh CW, Ratcliffe PJ (2003) Regulation of angiogenesis by hypoxia: role of the HIF system. Nat. Med. 9, 677-684
-
(2003)
Nat. Med.
, vol.9
, pp. 677-684
-
-
Pugh, C.W.1
Ratcliffe, P.J.2
-
240
-
-
0041819632
-
Tumor vaccines: From gene therapy to dendritic cells: The emerging frontier Urol
-
Vieweg J, Dannull J (2003) Tumor vaccines: from gene therapy to dendritic cells: the emerging frontier Urol. Clin. North Am. 30, 633-643
-
(2003)
Clin. North Am.
, vol.30
, pp. 633-643
-
-
Vieweg, J.1
Dannull, J.2
-
241
-
-
0038654360
-
Studying cancer families to identify kidney cancer genes Annu
-
Zbar B, Klausner R, Linehan WM (2003) Studying cancer families to identify kidney cancer genes Annu. Rev. Med. 54, 217-233
-
(2003)
Rev. Med.
, vol.54
, pp. 217-233
-
-
Zbar, B.1
Klausner, R.2
Linehan, W.M.3
-
244
-
-
0037061766
-
Genetic mechanisms of hepatocarcinogenesis
-
Feitelson MA et al (2001) Genetic mechanisms of hepatocarcinogenesis. Oncogene 21, 2593-2604
-
(2001)
Oncogene
, vol.21
, pp. 2593-2604
-
-
Feitelson, M.A.1
-
245
-
-
0036384160
-
Molecular pathogenesis of human hepatocellular carcinoma
-
Kern MA, Breuhahn K, Schirmacher P (2002) Molecular pathogenesis of human hepatocellular carcinoma. Adv. Cancer Res. 86, 67-112
-
(2002)
Adv. Cancer Res.
, vol.86
, pp. 67-112
-
-
Kern, M.A.1
Breuhahn, K.2
Schirmacher, P.3
-
246
-
-
0036216526
-
Genes involved in hepatocellular carcinoma: Deregulation in cell cycling and apoptosis
-
Tannapfel A, Wittekind C (2002) Genes involved in hepatocellular carcinoma: deregulation in cell cycling and apoptosis. Virchows Arch. 440, 345-352
-
(2002)
Virchows Arch.
, vol.440
, pp. 345-352
-
-
Tannapfel, A.1
Wittekind, C.2
-
247
-
-
0036699940
-
Molecular pathogenesis of human hepatocellular carcinoma
-
Thorgeirsson S, Grisham J (2002) Molecular pathogenesis of human hepatocellular carcinoma. Nat. Genet. 31, 339-346
-
(2002)
Nat. Genet.
, vol.31
, pp. 339-346
-
-
Thorgeirsson, S.1
Grisham, J.2
-
248
-
-
0042968962
-
Molecular viral oncology of hepatocellular carcinoma
-
Block TM, Mehta AS, Fimmel CJ, Jordan R (2003) Molecular viral oncology of hepatocellular carcinoma. Oncogene 22, 5093-5107
-
(2003)
Oncogene
, vol.22
, pp. 5093-5107
-
-
Block, T.M.1
Mehta, A.S.2
Fimmel, C.J.3
Jordan, R.4
-
251
-
-
0032954422
-
Molecular evolution of the metaplasia-dysplasia-adenocarcinoma sequence in the esophagus
-
Jankowski JA et al (1999) Molecular evolution of the metaplasia- dysplasia-adenocarcinoma sequence in the esophagus. Am. J. Pathol. 154, 965-973
-
(1999)
Am. J. Pathol.
, vol.154
, pp. 965-973
-
-
Jankowski, J.A.1
-
252
-
-
0034704880
-
Interleukin-1 polymorphisms associated with increased risk of gastric cancer
-
El-Omar EM et al. (2000) Interleukin-1 polymorphisms associated with increased risk of gastric cancer. Nature 404, 398-402
-
(2000)
Nature
, vol.404
, pp. 398-402
-
-
El-Omar, E.M.1
-
253
-
-
0037143090
-
Genetic susceptibility and gastric cancer risk
-
Gonzalez CA, Sala N, Capella G (2002) Genetic susceptibility and gastric cancer risk. Int. J. Cancer 100, 249-260
-
(2002)
Int. J. Cancer
, vol.100
, pp. 249-260
-
-
Gonzalez, C.A.1
Sala, N.2
Capella, G.3
-
254
-
-
0036108620
-
Cadherin and Catenin alterations in human cancer
-
Hajra KM, Fearon ER (2002) Cadherin and Catenin alterations in human cancer. Genes, Chromosomes Cancer 34, 255-268
-
(2002)
Genes, Chromosomes Cancer
, vol.34
, pp. 255-268
-
-
Hajra, K.M.1
Fearon, E.R.2
-
255
-
-
0036370334
-
Helicobacter pylori and gastrointestinal tract adenocarcinomas Nat
-
Peek RM, Blaser MJ (2002) Helicobacter pylori and gastrointestinal tract adenocarcinomas Nat. Rev. Cancer 2, 28-37
-
(2002)
Rev. Cancer
, vol.2
, pp. 28-37
-
-
Peek, R.M.1
Blaser, M.J.2
-
256
-
-
0037414170
-
Bacterial infections as a cause of cancer
-
Correa P (2003) Bacterial infections as a cause of cancer. J. Natl. Cancer Inst. 95, E3
-
(2003)
J. Natl. Cancer Inst.
, vol.95
-
-
Correa, P.1
-
257
-
-
0037143090
-
Genetic susceptibility and gastric cancer risk
-
Gonzalez CA, Sala N, Capella G (2002) Genetic susceptibility and gastric cancer risk. Int. J. Cancer 100, 249-260
-
(2002)
Int. J. Cancer
, vol.100
, pp. 249-260
-
-
Gonzalez, C.A.1
Sala, N.2
Capella, G.3
-
258
-
-
0042783125
-
Molecular mechanisms of carcinogenesis in gastric cancer
-
Höfler H, Becker KF (2003) Molecular mechanisms of carcinogenesis in gastric cancer. Rec. Res. Cancer Res. 162, 65-72
-
(2003)
Rec. Res. Cancer Res.
, vol.162
, pp. 65-72
-
-
Höfler, H.1
Becker, K.F.2
-
259
-
-
0042886962
-
Control of gut differentiation and intestinal-type gastric carcinogenesis
-
Yuasa Y (2003) Control of gut differentiation and intestinal-type gastric carcinogenesis. Nat. Rev. Cancer 3, 592-600
-
(2003)
Nat. Rev. Cancer
, vol.3
, pp. 592-600
-
-
Yuasa, Y.1
-
260
-
-
85047691456
-
Helicobacter pylori persistence: Biology and disease
-
Blaser MJ, Atherton JC (2004) Helicobacter pylori persistence: biology and disease. J. Clin. Invest. 113, 321-333
-
(2004)
J. Clin. Invest.
, vol.113
, pp. 321-333
-
-
Blaser, M.J.1
Atherton, J.C.2
-
261
-
-
1442310498
-
Focus on gastric cancer
-
Ushijima T, Sasako M (2004) Focus on gastric cancer. Cancer Cell 5, 121-125
-
(2004)
Cancer Cell
, vol.5
, pp. 121-125
-
-
Ushijima, T.1
Sasako, M.2
-
263
-
-
0034680102
-
Molecular portraits of human breast tumours
-
Perou CM et al (2000) Molecular portraits of human breast tumours. Nature 406, 747-752
-
(2000)
Nature
, vol.406
, pp. 747-752
-
-
Perou, C.M.1
-
264
-
-
0034707053
-
In search of the tumour-suppressor functions of BRCA1 and BRCA2
-
Scully R, Livingston DM (2000) In search of the tumour-suppressor functions of BRCA1 and BRCA2. Nature 408, 429-432
-
(2000)
Nature
, vol.408
, pp. 429-432
-
-
Scully, R.1
Livingston, D.M.2
-
266
-
-
0037137519
-
A gene-expression signature as a predictor of survival in breast cancer
-
van de Vijver et al (2002) A gene-expression signature as a predictor of survival in breast cancer. NEJM 347, 1999-2009
-
(2002)
NEJM
, vol.347
, pp. 1999-2009
-
-
Van De Vijver1
-
267
-
-
0037169354
-
Cancer susceptibility and the functions of BRCA1 and BRCA2
-
Venkitaraman AR (2000) Cancer susceptibility and the functions of BRCA1 and BRCA2. Cell 108, 171-182
-
(2000)
Cell
, vol.108
, pp. 171-182
-
-
Venkitaraman, A.R.1
-
268
-
-
0037204724
-
Connections and regulation of the human estrogen receptor
-
McDonnell DP, Norris JD (2002) Connections and regulation of the human estrogen receptor. Science 296, 1642-1644
-
(2002)
Science
, vol.296
, pp. 1642-1644
-
-
McDonnell, D.P.1
Norris, J.D.2
-
269
-
-
0037429725
-
The ErbB receptors and their role in cancer progression
-
Holbro T, Civenni G, Hynes NE (2003) The ErbB receptors and their role in cancer progression. Exp. Cell Res. 284, 99-110
-
(2003)
Exp. Cell Res.
, vol.284
, pp. 99-110
-
-
Holbro, T.1
Civenni, G.2
Hynes, N.E.3
-
270
-
-
0038244058
-
Gene expression predictors of breast cancer outcomes
-
Huang et al (2003) Gene expression predictors of breast cancer outcomes. Lancet 361, 1590-1596
-
(2003)
Lancet
, vol.361
, pp. 1590-1596
-
-
Huang1
-
271
-
-
0037304034
-
The biology of breast carcinoma
-
Keen JC, Davidson NE (2003) The biology of breast carcinoma. Cancer 97 Suppl. 825-833
-
(2003)
Cancer
, vol.97
, Issue.SUPPL.
, pp. 825-833
-
-
Keen, J.C.1
Davidson, N.E.2
-
272
-
-
0037226593
-
A molecular signature of metastasis in primary tumors
-
Ramaswamy S et al (2003) A molecular signature of metastasis in primary tumors. Nat. Genet. 33, 49-54
-
(2003)
Nat. Genet.
, vol.33
, pp. 49-54
-
-
Ramaswamy, S.1
-
273
-
-
0037429727
-
ErbBs in mammary development
-
Stern DF (2003) ErbBs in mammary development. Exp. Cell Res. 284, 89-98
-
(2003)
Exp. Cell Res.
, vol.284
, pp. 89-98
-
-
Stern, D.F.1
-
274
-
-
0037685164
-
Breast and ovarian cancer
-
Wooster R, Weber BL (2003) Breast and ovarian cancer. NEJM 348, 2339-2347
-
(2003)
NEJM
, vol.348
, pp. 2339-2347
-
-
Wooster, R.1
Weber, B.L.2
-
275
-
-
1642544604
-
Selective estrogen receptor modulation: Concept and consequences in the clinic
-
Jordan VC (2004) Selective estrogen receptor modulation: concept and consequences in the clinic. Cancer Cell 5, 207-213
-
(2004)
Cancer Cell
, vol.5
, pp. 207-213
-
-
Jordan, V.C.1
-
276
-
-
1942502234
-
Tracing the network connecting BRCA and Fanconi anaemia proteins
-
Venkitaraman AR (2004) Tracing the network connecting BRCA and Fanconi anaemia proteins. Nat. Rev. Cancer 4, 266-276
-
(2004)
Nat. Rev. Cancer
, vol.4
, pp. 266-276
-
-
Venkitaraman, A.R.1
-
279
-
-
0033153362
-
Osteomimetic properties of prostate cancer cells: A hypothesis supporting the predilection of prostate cancer metastasis and growth in the bone environment
-
Koeneman KS, Yeung F, Chung LWK (1999) Osteomimetic properties of prostate cancer cells: a hypothesis supporting the predilection of prostate cancer metastasis and growth in the bone environment. Prostate 39, 246-261
-
(1999)
Prostate
, vol.39
, pp. 246-261
-
-
Koeneman, K.S.1
Yeung, F.2
Chung, L.W.K.3
-
280
-
-
0033955413
-
Dysregulated expression of growth factors and their receptors in the development of prostate cancer
-
Djakiew D (2000) Dysregulated expression of growth factors and their receptors in the development of prostate cancer. Prostate 42, 150-160
-
(2000)
Prostate
, vol.42
, pp. 150-160
-
-
Djakiew, D.1
-
281
-
-
0035740250
-
Chromosomal deletions and tumor suppressor genes in prostate cancer
-
Dong JT (2001) Chromosomal deletions and tumor suppressor genes in prostate cancer. Cancer Metast. Rev. 20, 173-193
-
(2001)
Cancer Metast. Rev.
, vol.20
, pp. 173-193
-
-
Dong, J.T.1
-
282
-
-
0035496220
-
The development of androgen-independent prostate cancer
-
Feldman BJ, Feldman D (2001) The development of androgen-independent prostate cancer. Nat. Rev. Cancer 1, 34-45
-
(2001)
Nat. Rev. Cancer
, vol.1
, pp. 34-45
-
-
Feldman, B.J.1
Feldman, D.2
-
284
-
-
0036675220
-
Metastasis to bone: Causes, consequences and therapeutic opportunities
-
Mundy GR (2002) Metastasis to bone: causes, consequences and therapeutic
-
(2002)
Nat. Rev. Cancer
, vol.2
, pp. 584-593
-
-
Mundy, G.R.1
-
285
-
-
0036095853
-
Prostate cancer susceptibility genes
-
Simard J, Dumont M, Soucy P, Labrie F (2002) Prostate cancer susceptibility genes. Endocrinology 143, 2029-2040
-
(2002)
Endocrinology
, vol.143
, pp. 2029-2040
-
-
Simard, J.1
Dumont, M.2
Soucy, P.3
Labrie, F.4
-
287
-
-
0242692456
-
Molecular pathways to prostate cancer
-
Gonzalgo ML, Isaacs WB (2003) Molecular pathways to prostate cancer. J. Urol. 170, 2444-2452
-
(2003)
J. Urol.
, vol.170
, pp. 2444-2452
-
-
Gonzalgo, M.L.1
Isaacs, W.B.2
-
289
-
-
0242523099
-
The molecular genetics of prostate cancer
-
Visakorpi T (2003) The molecular genetics of prostate cancer. Urology 62, Suppl. 1, 3-10
-
(2003)
Urology
, vol.62
, Issue.SUPPL. 1
, pp. 3-10
-
-
Visakorpi, T.1
-
290
-
-
3843106187
-
GSTP1 CpG island hypermethylation as a molecular biomarker for prostate cancer
-
Nakayama M et al (2004) GSTP1 CpG island hypermethylation as a molecular biomarker for prostate cancer. J. Cell. Biochem. 91, 540-552
-
(2004)
J. Cell. Biochem.
, vol.91
, pp. 540-552
-
-
Nakayama, M.1
-
294
-
-
0036324027
-
Epidemiologic studies of folate and colorectal neoplasia: A review
-
Giovannucci E (2002) Epidemiologic studies of folate and colorectal neoplasia: a review. J. Nutr. 132, Suppl. 2350S-2355S
-
(2002)
J. Nutr.
, vol.132
, Issue.SUPPL.
-
-
Giovannucci, E.1
-
295
-
-
0035988620
-
The promise of biomarkers in cancer screening and detection
-
Negm RS, Verma M, Srivastava S (2002) The promise of biomarkers in cancer screening and detection. Trends Mol. Med. 8, 288-293
-
(2002)
Trends Mol. Med.
, vol.8
, pp. 288-293
-
-
Negm, R.S.1
Verma, M.2
Srivastava, S.3
-
296
-
-
0344394175
-
Retinoids in cancer therapy and chemoprevention: Promise meets resistance
-
Freemantle SJ, Spinella MJ, Dmitrovsky E (2003) Retinoids in cancer therapy and chemoprevention: promise meets resistance. Oncogene 22, 7305-7315
-
(2003)
Oncogene
, vol.22
, pp. 7305-7315
-
-
Freemantle, S.J.1
Spinella, M.J.2
Dmitrovsky, E.3
-
297
-
-
0038049147
-
Translational strategies for cancer prevention in liver
-
Kensler TW et al (2003) Translational strategies for cancer prevention in liver. Nat. Rev. Cancer 3, 321-329
-
(2003)
Nat. Rev. Cancer
, vol.3
, pp. 321-329
-
-
Kensler, T.W.1
-
298
-
-
0038013870
-
Challenges to cancer control by screening
-
Pollak MN, Foulkes WD (2003) Challenges to cancer control by screening. Nat. Rev. Cancer 3, 297-303
-
(2003)
Nat. Rev. Cancer
, vol.3
, pp. 297-303
-
-
Pollak, M.N.1
Foulkes, W.D.2
-
299
-
-
0141731350
-
Frontiers in cancer prevention research
-
Sabichi AL et al (2003) Frontiers in cancer prevention research. Cancer Res. 63, 5649-5655
-
(2003)
Cancer Res.
, vol.63
, pp. 5649-5655
-
-
Sabichi, A.L.1
-
300
-
-
1542410504
-
Genetic testing for cancer susceptibility: The promise and the pitfalls
-
Lerman C, Shields AE (2004) Genetic testing for cancer susceptibility: the promise and the pitfalls. Nat. Rev. Cancer 4, 235-241
-
(2004)
Nat. Rev. Cancer
, vol.4
, pp. 235-241
-
-
Lerman, C.1
Shields, A.E.2
-
301
-
-
0034887647
-
Genomic approaches to the pathogenesis of hematologic malignancies
-
Golub TR (2001) Genomic approaches to the pathogenesis of hematologic malignancies. Curr. Opin. Hematol. 81, 252-261
-
(2001)
Curr. Opin. Hematol.
, vol.81
, pp. 252-261
-
-
Golub, T.R.1
-
302
-
-
0035845511
-
Gene expression patterns of breast carcinomas distinguish tumor subclasses with clinical implications
-
Sorlie T et al (2001) Gene expression patterns of breast carcinomas distinguish tumor subclasses with clinical implications. PNAS 98, 10869-10874
-
(2001)
PNAS
, vol.98
, pp. 10869-10874
-
-
Sorlie, T.1
-
303
-
-
0036884307
-
Bloodborne biomolecular markers in prostate cancer: Development and progression
-
Bok RA, Small EJ (2002) Bloodborne biomolecular markers in prostate cancer: development and progression. Nat. Rev. Cancer 2, 918-926
-
(2002)
Nat. Rev. Cancer
, vol.2
, pp. 918-926
-
-
Bok, R.A.1
Small, E.J.2
-
304
-
-
0036898190
-
Molecular portraits and the family tree of cancer
-
Chung CH, Bernard PS, Perou CM (2002) Molecular portraits and the family tree of cancer. Nat. Genet. 32 Suppl. 533-540
-
(2002)
Nat. Genet.
, vol.32
, Issue.SUPPL.
, pp. 533-540
-
-
Chung, C.H.1
Bernard, P.S.2
Perou, C.M.3
-
305
-
-
18244409687
-
Gene expression profiling predicts clinical outcome of breast cancer
-
van't Veer et al (2002) Gene expression profiling predicts clinical outcome of breast cancer. Nature 415, 530-536
-
(2002)
Nature
, vol.415
, pp. 530-536
-
-
Van't Veer1
-
306
-
-
0036931648
-
Recent advances in the pharmacogenetics of cancer chemotherapy
-
Watters JW, McLeod HL (2002) Recent advances in the pharmacogenetics of cancer chemotherapy. Curr. Opin. Mol. Therapeut. 4, 565-571
-
(2002)
Curr. Opin. Mol. Therapeut.
, vol.4
, pp. 565-571
-
-
Watters, J.W.1
McLeod, H.L.2
-
307
-
-
0036154815
-
The potential prognostic, predictive, and therapeutic values of DNA methylation in cancer
-
Widschwendter M, Jones PA (2002) The potential prognostic, predictive, and therapeutic values of DNA methylation in cancer. Clin. Cancer Res. 8, 17-21
-
(2002)
Clin. Cancer Res.
, vol.8
, pp. 17-21
-
-
Widschwendter, M.1
Jones, P.A.2
-
308
-
-
0037648348
-
The case for early detection
-
Etzioni R et al (2003) The case for early detection. Nat. Rev. Cancer 3, 243-252
-
(2003)
Nat. Rev. Cancer
, vol.3
, pp. 243-252
-
-
Etzioni, R.1
-
310
-
-
0038576158
-
The power and the promise of DNA methylation markers
-
Laird PW (2003) The power and the promise of DNA methylation markers. Nat. Rev. Cancer 3, 253-266
-
(2003)
Nat. Rev. Cancer
, vol.3
, pp. 253-266
-
-
Laird, P.W.1
-
311
-
-
0037310651
-
Classification of cancers by expression profiling
-
Liu ET (2003) Classification of cancers by expression profiling. Curr. Opin. Genet. Devel. 13, 97-103
-
(2003)
Curr. Opin. Genet. Devel.
, vol.13
, pp. 97-103
-
-
Liu, E.T.1
-
312
-
-
0242405575
-
Advantages and limitations of microarray technology in human cancer
-
Russo G, Zegar C, Giordano A (2003) Advantages and limitations of microarray technology in human cancer. Oncogene 22. 6497-6507
-
(2003)
Oncogene
, vol.22
, pp. 6497-6507
-
-
Russo, G.1
Zegar, C.2
Giordano, A.3
-
313
-
-
0036319682
-
Pharmacogenomics
-
Tribut O et al (2003) Pharmacogenomics. Med. Sci. Monit. 8, RA152-163
-
(2003)
Med. Sci. Monit.
, vol.8
-
-
Tribut, O.1
-
314
-
-
0038040665
-
Detection of minimal residual disease in hematological malignancies by real-time quantitative PCR: Principles, approaches, and laboratory aspects
-
van der Velde VHJ et al (2003) Detection of minimal residual disease in hematological malignancies by real-time quantitative PCR: principles, approaches, and laboratory aspects. Leukemia 17, 1013-1034
-
(2003)
Leukemia
, vol.17
, pp. 1013-1034
-
-
Van Der Velde, V.H.J.1
-
319
-
-
0035037366
-
Molecular targets for breast cancer therapy and prevention
-
Bange J, Zwick E, Ullrich A (2001) Molecular targets for breast cancer therapy and prevention. Nat. Med. 7, 548-552
-
(2001)
Nat. Med.
, vol.7
, pp. 548-552
-
-
Bange, J.1
Zwick, E.2
Ullrich, A.3
-
320
-
-
0035902080
-
Progress in human tumour immunology and immunotherapy
-
Rosenberg SA (2001) Progress in human tumour immunology and immunotherapy. Nature 411, 380-384
-
(2001)
Nature
, vol.411
, pp. 380-384
-
-
Rosenberg, S.A.1
-
321
-
-
0035974798
-
Achilles' heel of cancer? (i.e.p53 inactivation)
-
Vogelstein B, Kinzler KW (2001) Achilles' heel of cancer? (i.e.p53 inactivation) Nature 412, 865-866
-
(2001)
Nature
, vol.412
, pp. 865-866
-
-
Vogelstein, B.1
Kinzler, K.W.2
-
322
-
-
0036747985
-
Farnesyl transferase inhibitors: A major breakthrough in anticancer therapy?
-
Caponigro F (2002) Farnesyl transferase inhibitors: a major breakthrough in anticancer therapy? Anticancer Drugs 13, 891-897
-
(2002)
Anticancer Drugs
, vol.13
, pp. 891-897
-
-
Caponigro, F.1
-
323
-
-
0036782706
-
Transcription factors as targets for cancer therapy
-
Darnell JE (2002) Transcription factors as targets for cancer therapy. Nat. Rev. Cancer 2, 740-749
-
(2002)
Nat. Rev. Cancer
, vol.2
, pp. 740-749
-
-
Darnell, J.E.1
-
324
-
-
0036519363
-
DNA and its associated processes as targets for cancer therapy
-
Hurley LH (2002) DNA and its associated processes as targets for cancer therapy. Nat. Rev. Cancer 2, 188-200
-
(2002)
Nat. Rev. Cancer
, vol.2
, pp. 188-200
-
-
Hurley, L.H.1
-
325
-
-
0037169358
-
Apoptosis: A link between cancer genetics and chemotherapy
-
Johnstone RW, Ruefli AA, Lowe SW (2002) Apoptosis: a link between cancer genetics and chemotherapy. Cell 108, 153-164
-
(2002)
Cell
, vol.108
, pp. 153-164
-
-
Johnstone, R.W.1
Ruefli, A.A.2
Lowe, S.W.3
-
326
-
-
0037429652
-
ErbB-targeted therapeutic approaches in human cancer
-
Arteaga CL (2003) ErbB-targeted therapeutic approaches in human cancer. Exp. Cell Res. 284, 122-130
-
(2003)
Exp. Cell Res.
, vol.284
, pp. 122-130
-
-
Arteaga, C.L.1
-
327
-
-
0242692686
-
Growth factor receptor tyrosine kinase inhibitors: Clinical development and potential for prostate cancer therapy
-
Blackledge G (2003) Growth factor receptor tyrosine kinase inhibitors: clinical development and potential for prostate cancer therapy. J. Urol. 170, S77-S83
-
(2003)
J. Urol.
, vol.170
-
-
Blackledge, G.1
-
328
-
-
0041466445
-
Specific targeted therapy of chronic myelogenous leukemia with imatinib
-
Deininger MW, Druker BJ (2003) Specific targeted therapy of chronic myelogenous leukemia with imatinib. Pharmacol. Rev. 55, 401-423
-
(2003)
Pharmacol. Rev.
, vol.55
, pp. 401-423
-
-
Deininger, M.W.1
Druker, B.J.2
-
329
-
-
0141757504
-
P53 and radiation responses
-
Fei P, el-Deiry WS (2003) P53 and radiation responses. Oncogene 22, 5774-5783
-
(2003)
Oncogene
, vol.22
, pp. 5774-5783
-
-
Fei, P.1
El-Deiry, W.S.2
-
330
-
-
0038387495
-
Cancer revoked: Oncogenes as therapeutic targets
-
Felscher DW (2003) Cancer revoked: oncogenes as therapeutic targets. Nat. Rev. Cancer 3, 375-379
-
(2003)
Nat. Rev. Cancer
, vol.3
, pp. 375-379
-
-
Felscher, D.W.1
-
331
-
-
0038718522
-
Developing inhibitors of the epidermal growth factor receptor for cancer treatment
-
Grünwald V, Hidalgo M (2003) Developing inhibitors of the Epidermal Growth Factor Receptor for cancer treatment. J. Natl. Cancer Inst. 95, 851-867
-
(2003)
J. Natl. Cancer Inst.
, vol.95
, pp. 851-867
-
-
Grünwald, V.1
Hidalgo, M.2
-
332
-
-
0042237781
-
Rethinking clinical trials for cytostatic drugs
-
Millar AW, Lynch KP (2003) Rethinking clinical trials for cytostatic drugs. Nat. Rev. Cancer 3, 540-544
-
(2003)
Nat. Rev. Cancer
, vol.3
, pp. 540-544
-
-
Millar, A.W.1
Lynch, K.P.2
-
334
-
-
0141994853
-
Towards integrated clinico-genomic models for personalized medicine: Combining gene expression signatures and clinical features in breast cancer outcomes prediction
-
Nevins J et al (2003) Towards integrated clinico-genomic models for personalized medicine: combining gene expression signatures and clinical features in breast cancer outcomes prediction. Hum. Mol. Genet. 12. Spec. No. 2, R153-157
-
(2003)
Hum. Mol. Genet.
, vol.12
, Issue.2
-
-
Nevins, J.1
-
335
-
-
0037899935
-
Improving the evaluation of new cancer treatments: Challenges and opportunities
-
Rothenberg ML, Carbone DP, Johnson DH (2003) Improving the evaluation of new cancer treatments: challenges and opportunities. Nat. Rev. Cancer 3, 303-309
-
(2003)
Nat. Rev. Cancer
, vol.3
, pp. 303-309
-
-
Rothenberg, M.L.1
Carbone, D.P.2
Johnson, D.H.3
-
336
-
-
0346125401
-
Blocked pathways: FTIs shut down oncogenic signals
-
Sebti SM (2003) Blocked pathways: FTIs shut down oncogenic signals. Oncologist 8 Suppl. 3, 30-38
-
(2003)
Oncologist
, vol.8
, Issue.SUPPL. 3
, pp. 30-38
-
-
Sebti, S.M.1
-
337
-
-
0344585042
-
Activation of tyrosine kinases in cancer
-
Vlahovic G, Crawford J (2003) Activation of tyrosine kinases in cancer. Oncologist 8, 531-538.
-
(2003)
Oncologist
, vol.8
, pp. 531-538
-
-
Vlahovic, G.1
Crawford, J.2
-
338
-
-
0346059610
-
Harnessing apoptosis for improved anticancer gene therapy
-
Waxman DJ, Schwartz PS (2003) Harnessing apoptosis for improved anticancer gene therapy. Cancer Res. 63, 8563-8572
-
(2003)
Cancer Res.
, vol.63
, pp. 8563-8572
-
-
Waxman, D.J.1
Schwartz, P.S.2
-
339
-
-
0842329999
-
Angiogenesis inhibitors in clinical development; where are we now and where are we going
-
Eskens FALM (2004) Angiogenesis inhibitors in clinical development; where are we now and where are we going. Brit. J. Cancer 90, 1-7
-
(2004)
Brit. J. Cancer
, vol.90
, pp. 1-7
-
-
Eskens, F.A.L.M.1
-
340
-
-
2142714017
-
Monoclonal antibodies as therapeutic agents for cancer
-
Harris M (2004) Monoclonal antibodies as therapeutic agents for cancer. Lancet Oncol. 5, 292-302
-
(2004)
Lancet Oncol.
, vol.5
, pp. 292-302
-
-
Harris, M.1
-
341
-
-
1642544604
-
Selective estrogen receptor modulation: Concept and consequences in the clinic
-
Jordan VC (2004) Selective estrogen receptor modulation: concept and consequences in the clinic. Cancer Cell 5, 207-213
-
(2004)
Cancer Cell
, vol.5
, pp. 207-213
-
-
Jordan, V.C.1
-
342
-
-
2942648713
-
The p53 pathway: Targets for the development of novel cancer therapeutics
-
Wang S, El-Deiry WS (2004) The p53 pathway: targets for the development of novel cancer therapeutics. Cancer Treat. Res. 119, 175-187
-
(2004)
Cancer Treat. Res.
, vol.119
, pp. 175-187
-
-
Wang, S.1
El-Deiry, W.S.2
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