Raf proteins and cancer: B-Raf is identified as a mutational target

Biochimica et Biophysica Acta - Reviews on Cancer

Volumn 1653, Issue 1, 2003, Pages 25-40

  Mercer, Kathryn E ^a   Pritchard, Catrin A ^a  

^a UNIVERSITY OF LEICESTER   (United Kingdom)

Author keywords

Malignant melanoma; Mutation; Raf protein

Indexed keywords

GLUTAMIC ACID; MITOGEN ACTIVATED PROTEIN KINASE; NUCLEOTIDE; RAF PROTEIN; SERINE; THREONINE; VALINE;

BIOCHEMISTRY; BRAF GENE; CANCER; CANCER THERAPY; CELL MEMBRANE; CELL TYPE; CHICKEN; COLON CANCER; DRUG TARGETING; ENZYME ACTIVITY; GENE; GENE ACTIVATION; GENE ACTIVITY; GENE CONTROL; GENE MUTATION; HUMAN; MELANOMA; MUTATIONAL ANALYSIS; NONHUMAN; ONCOGENE; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; REVIEW; SEQUENCE HOMOLOGY; SIGNAL TRANSDUCTION;

EID: 0038697566     PISSN: 0304419X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0304-419X(03)00016-7     Document Type: Review

References (151)

1. Rapp U.R., Goldsborough M.D., Mark G.E., Bonner T.I., Groffen J., Reynolds F.H. Jr., Stephenson J.R. Proc. Natl. Acad. Sci. U. S. A. 80:1983;4218-4222.
2. Jansen H.W., Lurz R., Bister K., Bonner T.I., Mark G.E., Rapp U.R. Nature. 307:1984;281-284.
3. Sutrave P., Bonner T.I., Rapp U.R., Jansen H.W., Patschinsky T., Bister K. Nature. 309:1984;85-88.
4. Avruch J., Zhang X.F., Kyriakis J.M. Trends Biochem. Sci. 19:1994;279-283.
5. Bos J.L. Cancer Res. 49:1989;4682-4689.
6. Marshall C.J. Curr. Opin. Genet. Dev. 4:1994;82-89.
7. Marais R., Marshall C.J. Cancer Surv. 27:1996;101-125.
8. Davies H., Bignell G.R., Cox C., Stephens P., Edkins S., Clegg S., Teague J., Woffendin H., Garnett M.J., Bottomley W., Davis N., Dicks E., Ewing R., Floyd Y., Gray K., Hall S., Hawes R., Hughes J., Kosmidou V., Menzies A., Mould C., Parker A., Stevens C., Watt S., Hooper S., Wilson R., Jayatilake H., Gusterson B.A., Cooper C., Shipley J., Hargrave D., Pritchard-Jones K., Maitland N., Chenevix-Trench G., Riggins G.J., Bigner D.D., Palmieri G., Cossu A., Flanagan A., Nicholson A., Ho J.W., Leung S.Y., Yuen S.T., Weber B.L., Seigler H.F., Darrow T.L., Paterson H., Marais R., Marshall C.J., Wooster R., Stratton M.R., Futreal P.A. Nature. 417:2002;949-954.
9. Wojnowski L., Stancato L.F., Larner A.C., Rapp U.R., Zimmer A. Mech. Dev. 91:2000;97-104.
10. Hüser M., Luckett J., Chiloeches A., Mercer K., Iwobi M., Giblett S., Sun X.M., Brown J., Marais R., Pritchard C. EMBO J. 20:2001;1940-1951.
11. Mikula M., Schreiber M., Husak Z., Kucerova L., Ruth J., Wieser R., Zatloukal K., Beug H., Wagner E.F., Baccarini M. EMBO J. 20:2001;1952-1962.
12. Mason C.S., Springer C.J., Cooper R.G., Superti-Furga G., Marshall C.J., Marais R. EMBO J. 18:1999;2137-2148.
13. Zhang B.H., Guan K.L. EMBO J. 19:2000;5429-5439.
14. Huebner K., ar-Rushdi A., Griffin C.A., Isobe M., Kozak C., Emanuel B.S., Nagarajan L., Cleveland J.L., Bonner T.I., Goldsborough M.D.et al. Proc. Natl. Acad. Sci. U. S. A. 83:1986;3934-3938.
15. Ikawa S., Fukui M., Ueyama Y., Tamaoki N., Yamamoto T., Toyoshima K. Mol. Cell. Biol. 8:1988;2651-2654.
16. Balmain A., Pragnell I.B. Nature. 303:1983;72-74.
17. Vousden K.H., Marshall C.J. EMBO J. 3:1984;913-917.
18. Johnson L., Mercer K., Greenbaum D., Bronson R.T., Crowley D., Tuveson D.A., Jacks T. Nature. 410:2001;1111-1116.
19. Schaeffer H.J., Weber M.J. Mol. Cell. Biol. 19:1999;2435-2444.
20. Pearson G., Robinson F., Beers Gibson T., Xu B.E., Karandikar M., Berman K., Cobb M.H. Endocr. Rev. 22:2001;153-183.
21. Hanahan D., Weinberg R.A. Cell. 100:2000;57-70.
22. Hoshino R., Chatani Y., Yamori T., Tsuruo T., Oka H., Yoshida O., Shimada Y., Ari-i S., Wada H., Fujimoto J., Kohno M. Oncogene. 18:1999;813-822.
23. Berger D.H., Jardines L.A., Chang H., Ruggeri B. J. Surg. Res. 69:1997;199-204.
24. Callans L.S., Naama H., Khandelwal M., Plotkin R., Jardines L. Ann. Surg. Oncol. 2:1995;38-42.
25. Storm S.M., Brennscheidt U., Sithanandam G., Rapp U.R. Crit. Rev. Oncog. 2:1990;1-8.
26. Pollock P.M., Harper U.L., Hansen K.S., Yudt L.M., Stark M., Robbins C.M., Moses T.Y., Hostetter G., Wagner U., Kakareka J., Salem G., Pohida T., Heenan P., Duray P., Kallioniemi O., Hayward N.K., Trent J.M., Meltzer P.S. Nat. Genet. 33:2003;19-20.
27. Rajagopalan H., Bardelli A., Lengauer C., Kinzler K.W., Vogelstein B., Velculescu V.E. Nature. 418:2002;934.
28. Yuen S.T., Davies H., Chan T.L., Ho J.W., Bignell G.R., Cox C., Stephens P., Edkins S., Tsui W.W., Chan A.S., Futreal P.A., Stratton M.R., Wooster R., Leung S.Y. Cancer Res. 62:2002;6451-6455.
29. Brose M.S., Volpe P., Feldman M., Kumar M., Rishi I., Gerrero R., Einhorn E., Herlyn M., Minna J., Nicholson A., Roth J.A., Albelda S.M., Davies H., Cox C., Brignell G., Stephens P., Futreal P.A., Wooster R., Stratton M.R., Weber B.L. Cancer Res. 62:2002;6997-7000.
30. Naoki K., Chen T.H., Richards W.G., Sugarbaker D.J., Meyerson M. Cancer Res. 62:2002;7001-7003.
31. Storm S.M., Cleveland J.L., Rapp U.R. Oncogene. 5:1990;345-351.
32. Luckett J.C., Huser M.B., Giagtzoglou N., Brown J.E., Pritchard C.A. Cell Growth Differ. 11:2000;163-171.
33. Barnier J.V., Papin C., Eychene A., Lecoq O., Calothy G. J. Biol. Chem. 270:1995;23381-23389.
34. Busca R., Abbe P., Mantoux F., Aberdam E., Peyssonnaux C., Eychene A., Ortonne J.P., Ballotti R. EMBO J. 19:2000;2900-2910.
35. Scheffler J.E., Waugh D.S., Bekesi E., Kiefer S.E., LoSardo J.E., Neri A., Prinzo K.M., Tsao K.L., Wegrzynski B., Emerson S.D.et al. J. Biol. Chem. 269:1994;22340-22346.
36. Vojtek A.B., Hollenberg S.M., Cooper J.A. Cell. 74:1993;205-214.
37. Mott H.R., Carpenter J.W., Zhong S., Ghosh S., Bell R.M., Campbell S.L. Proc. Natl. Acad. Sci. U. S. A. 93:1996;8312-8317.
38. Beck T.W., Huleihel M., Gunnell M., Bonner T.I., Rapp U.R. Nucleic Acids Res. 15:1987;595-609.
39. Ghosh S., Bell R.M. J. Biol. Chem. 269:1994;30785-30788.
40. Daum G., Eisenmann-Tappe I., Fries H.W., Troppmair J., Rapp U.R. Trends Biochem. Sci. 19:1994;474-480.
41. Morrison D.K., Cutler R.E. Curr. Opin. Cell Biol. 9:1997;174-179.
42. Johnson L.N., Lowe E.D., Noble M.E., Owen D.J. FEBS Lett. 430:1998;1-11.
43. Papin C., Denouel-Galy A., Laugier D., Calothy G., Eychene A. J. Biol. Chem. 273:1998;24939-24947.
44. Stephens R.M., Sithanandam G., Copeland T.D., Kaplan D.R., Rapp U.R., Morrison D.K. Mol. Cell. Biol. 12:1992;3733-3742.
45. Hemmer W., McGlone M., Tsigelny I., Taylor S.S. J. Biol. Chem. 272:1997;16946-16954.
46. Grant B.D., Hemmer W., Tsigelny I., Adams J.A., Taylor S.S. Biochemistry. 37:1998;7708-7715.
47. Guan K.L., Figueroa C., Brtva T.R., Zhu T., Taylor J., Barber T.D., Vojtek A.B. J. Biol. Chem. 275:2000;27354-27359.
48. Kolch W., Heidecker G., Lloyd P., Rapp U.R. Nature. 349:1991;426-428.
49. Koide H., Satoh T., Nakafuku M., Kaziro Y. Proc. Natl. Acad. Sci. U. S. A. 90:1993;8683-8686.
50. Van Aelst L., Barr M., Marcus S., Polverino A., Wigler M. Proc. Natl. Acad. Sci. U. S. A. 90:1993;6213-6217.
51. Warne P.H., Viciana P.R., Downward J. Nature. 364:1993;352-355.
52. Zhang X.F., Settleman J., Kyriakis J.M., Takeuchi-Suzuki E., Elledge S.J., Marshall M.S., Bruder J.T., Rapp U.R., Avruch J. Nature. 364:1993;308-313.
53. Brtva T.R., Drugan J.K., Ghosh S., Terrell R.S., Campbell-Burk S., Bell R.M., Der C.J. J. Biol. Chem. 270:1995;9809-9812.
54. Hu C.D., Kariya K., Tamada M., Akasaka K., Shirouzu M., Yokoyama S., Kataoka T. J. Biol. Chem. 270:1995;30274-30277.
55. Chuang E., Barnard D., Hettich L., Zhang X.F., Avruch J., Marshall M.S. Mol. Cell. Biol. 14:1994;5318-5325.
56. Voice J.K., Klemke R.L., Le A., Jackson J.H. J. Biol. Chem. 274:1999;17164-17170.
57. Leevers S.J., Paterson H.F., Marshall C.J. Nature. 369:1994;411-414.
58. Stokoe D., Macdonald S.G., Cadwallader K., Symons M., Hancock J.F. Science. 264:1994;1463-1467.
59. Marais R., Light Y., Paterson H.F., Mason C.S., Marshall C.J. J. Biol. Chem. 272:1997;4378-4383.
60. Shinkai M., Masuda T., Kariya K., Tamada M., Shirouzu M., Yokoyama S., Kataoka T. Biochem. Biophys. Res. Commun. 223:1996;729-734.
61. Okada T., Hu C.D., Jin T.G., Kariya K., Yamawaki-Kataoka Y., Kataoka T. Mol. Cell. Biol. 19:1999;6057-6064.
62. Yamamori B., Kuroda S., Shimizu K., Fukui K., Ohtsuka T., Takai Y. J. Biol. Chem. 270:1995;11723-11726.
63. Hamilton M., Wolfman A. Oncogene. 16:1998;1417-1428.
64. Hamilton M., Liao J., Cathcart M.K., Wolfman A. J. Biol. Chem. 276:2001;29079-29090.
65. Weber C.K., Slupsky J.R., Kalmes H.A., Rapp U.R. Cancer Res. 61:2001;3595-3598.
66. Mizutani S., Inouye K., Koide H., Kaziro Y. FEBS Lett. 507:2001;295-298.
67. Vossler M.R., Yao H., York R.D., Pan M.G., Rim C.S., Stork P.J. Cell. 89:1997;73-82.
68. York R.D., Yao H., Dillon T., Ellig C.L., Eckert S.P., McCleskey E.W., Stork P.J. Nature. 392:1998;622-626.
69. Bos J.L., de Rooij J., Reedquist K.A. Nat. Rev., Mol. Cell Biol. 2:2001;369-377.
70. Rosario M., Paterson H.F., Marshall C.J. EMBO J. 18:1999;1270-1279.
71. Dhillon A.S., Meikle S., Yazici Z., Eulitz M., Kolch W. EMBO J. 21:2002;64-71.
72. King A.J., Sun H., Diaz B., Barnard D., Miao W., Bagrodia S., Marshall M.S. Nature. 396:1998;180-183.
73. Bagrodia S., Cerione R.A. Trends Cell Biol. 9:1999;350-355.
74. Daniels R.H., Bokoch G.M. Trends Biochem. Sci. 24:1999;350-355.
75. Sun H., King A.J., Diaz H.B., Marshall M.S. Curr. Biol. 10:2000;281-284.
76. Chiloeches A., Mason C.S., Marais R. Mol. Cell. Biol. 21:2001;2423-2434.
77. Zhang B.H., Tang E.D., Zhu T., Greenberg M.E., Vojtek A.B., Guan K.L. J. Biol. Chem. 276:2001;31620-31626.
78. Kolch W. Biochem. J. 351:2000;289-305.
79. Peyssonnaux C., Eychene A. Biol. Cell. 93:2001;53-62.
80. Schaeffer H.J., Catling A.D., Eblen S.T., Collier L.S., Krauss A., Weber M.J. Science. 281:1998;1668-1671.
81. Yeung K., Seitz T., Li S., Janosch P., McFerran B., Kaiser C., Fee F., Katsanakis K.D., Rose D.W., Mischak H., Sedivy J.M., Kolch W. Nature. 401:1999;173-177.
82. Cacace A.M., Michaud N.R., Therrien M., Mathes K., Copeland T., Rubin G.M., Morrison D.K. Mol. Cell. Biol. 19:1999;229-240.
83. Denouel-Galy A., Douville E.M., Warne P.H., Papin C., Laugier D., Calothy G., Downward J., Eychene A. Curr. Biol. 8:1998;46-55.
84. Yu W., Fantl W.J., Harrowe G., Williams L.T. Curr. Biol. 8:1998;56-64.
85. Xing H., Kornfeld K., Muslin A.J. Curr. Biol. 7:1997;294-300.
86. Therrien M., Michaud N.R., Rubin G.M., Morrison D.K. Genes Dev. 10:1996;2684-2695.
87. Nguyen A., Burack W.R., Stock J.L., Kortum R., Chaika O.V., Afkarian M., Muller W.J., Murphy K.M., Morrison D.K., Lewis R.E., McNeish J., Shaw A.S. Mol. Cell. Biol. 22:2002;3035-3045.
88. Catling A.D., Reuter C.W., Cox M.E., Parsons S.J., Weber M.J. J. Biol. Chem. 269:1994;30014-30021.
89. Dent P., Haser W., Haystead T.A., Vincent L.A., Roberts T.M., Sturgill T.W. Science. 257:1992;1404-1407.
90. Howe L.R., Leevers S.J., Gomez N., Nakielny S., Cohen P., Marshall C.J. Cell. 71:1992;335-342.
91. Kyriakis J.M., App H., Zhang X.F., Banerjee P., Brautigan D.L., Rapp U.R., Avruch J. Nature. 358:1992;417-421.
92. Pritchard C.A., Samuels M.L., Bosch E., McMahon M. Mol. Cell. Biol. 15:1995;6430-6442.
93. Reuter C.W., Catling A.D., Jelinek T., Weber M.J. J. Biol. Chem. 270:1995;7644-7655.
94. Alessi D.R., Saito Y., Campbell D.G., Cohen P., Sithanandam G., Rapp U., Ashworth A., Marshall C.J., Cowley S. EMBO J. 13:1994;1610-1619.
95. Yan M., Templeton D.J. J. Biol. Chem. 269:1994;19067-19073.
96. Zheng C.F., Guan K.L. EMBO J. 13:1994;1123-1131.
97. Catling A.D., Schaeffer H.J., Reuter C.W., Reddy G.R., Weber M.J. Mol. Cell. Biol. 15:1995;5214-5225.
98. Papin C., Eychene A., Brunet A., Pages G., Pouyssegur J., Calothy G., Barnier J.V. Oncogene. 10:1995;1647-1651.
99. Jaiswal R.K., Moodie S.A., Wolfman A., Landreth G.E. Mol. Cell. Biol. 14:1994;6944-6953.
100. Eychene A., Dusanter-Fourt I., Barnier J.V., Papin C., Charon M., Gisselbrecht S., Calothy G. Oncogene. 10:1995;1159-1165.
101. Jaiswal R.K., Weissinger E., Kolch W., Landreth G.E. J. Biol. Chem. 271:1996;23626-23629.
102. Traverse S., Cohen P. FEBS Lett. 350:1994;13-18.
103. Kao S., Jaiswal R.K., Kolch W., Landreth G.E. J. Biol. Chem. 276:2001;18169-18177.
104. Moodie S.A., Paris M.J., Kolch W., Wolfman A. Mol. Cell. Biol. 14:1994;7153-7162.
105. Papin C., Denouel A., Calothy G., Eychene A. Oncogene. 12:1996;2213-2221.
106. Gomez E., Pritchard C., Herbert T.P. J. Biol. Chem. 2:2002;2.
107. Pritchard C.A., Bolin L., Slattery R., Murray R., McMahon M. Curr. Biol. 6:1996;614-617.
108. Mercer K., Chiloeches A., Huser M., Kiernan M., Marais R., Pritchard C. Oncogene. 21:2002;347-355.
109. Wojnowski L., Zimmer A.M., Beck T.W., Hahn H., Bernal R., Rapp U.R., Zimmer A. Nat. Genet. 16:1997;293-297.
110. Brummer T., Shaw P.E., Reth M., Misawa Y. EMBO J. 21:2002;5611-5622.
111. Newton Bishop J.A. Cancer Metastasis Rev. 16:1997;141-154.
112. Ruas M., Peters G. Biochim. Biophys. Acta. 1378:1998;F115-F177.
113. Flores J.F., Walker G.J., Glendening J.M., Haluska F.G., Castresana J.S., Rubio M.P., Pastorfide G.C., Boyer L.A., Kao W.H., Bulyk M.L., Barnhill R.L., Hayward N.K., Housman D.E., Fountain J.W. Cancer Res. 56:1996;5023-5032.
114. Funk J.O., Schiller P.I., Barrett M.T., Wong D.J., Kind P., Sander C.A. J. Cutan. Pathol. 25:1998;291-296.
115. Rizos H., Darmanian A.P., Indsto J.O., Shannon J.A., Kefford R.F., Mann G.J. Melanoma Res. 9:1999;10-19.
116. Krimpenfort P., Quon K.C., Mooi W.J., Loonstra A., Berns A. Nature. 413:2001;83-86.
117. Sharpless N.E., Bardeesy N., Lee K.H., Carrasco D., Castrillon D.H., Aguirre A.J., Wu E.A., Horner J.W., DePinho R.A. Nature. 413:2001;86-91.
118. Kumar R., Sauroja I., Punnonen K., Jansen C., Hemminki K. Genes Chromosomes Cancer. 23:1998;273-277.
119. Lee J.Y., Dong S.M., Shin M.S., Kim S.Y., Lee S.H., Kang S.J., Lee J.D., Kim C.S., Kim S.H., Yoo N.J. Biochem. Biophys. Res. Commun. 237:1997;667-672.
120. Papp T., Pemsel H., Zimmermann R., Bastrop R., Weiss D.G., Schiffmann D. J. Med. Genet. 36:1999;610-614.
121. Zuo L., Weger J., Yang Q., Goldstein A.M., Tucker M.A., Walker G.J., Hayward N., Dracopoli N.C. Nat. Genet. 12:1996;97-99.
122. Woods D., Parry D., Cherwinski H., Bosch E., Lees E., McMahon M. Mol. Cell. Biol. 17:1997;5598-5611.
123. Ewanowich C., Brynes R.K., Medeiros L., McCourty A., Lai R. Arch. Pathol. Lab. Med. 125:2001;208-210.
124. Georgieva J., Sinha P., Schadendorf D. J. Clin. Pathol. 54:2001;229-235.
125. Trotter M.J., Tang L., Tron V.A. J. Cutan. Pathol. 24:1997;265-271.
126. Sparrow L.E., Eldon M.J., English D.R., Heenan P.J. Am. J. Dermatopathol. 20:1998;255-261.
127. LaBaer J., Garrett M.D., Stevenson L.F., Slingerland J.M., Sandhu C., Chou H.S., Fattaey A., Harlow E. Genes Dev. 11:1997;847-862.
128. Bartek J., Lukas J., Bartkova J. J. Pathol. 187:1999;95-99.
129. Welcker M., Lukas J., Strauss M., Bartek J. Cancer Res. 58:1998;5053-5056.
130. Halaban R. Cancer Metastasis Rev. 18:1999;333-343.
131. Kerkhoff E., Rapp U.R. Mol. Cell. Biol. 17:1997;2576-2586.
132. Sewing A., Wiseman B., Lloyd A.C., Land H. Mol. Cell. Biol. 17:1997;5588-5597.
133. Zhu J., Woods D., McMahon M., Bishop J.M. Genes Dev. 12:1998;2997-3007.
134. Cook S.J., Aziz N., McMahon M. Mol. Cell. Biol. 19:1999;330-341.
135. Ries S., Biederer C., Woods D., Shifman O., Shirasawa S., Sasazuki T., McMahon M., Oren M., McCormick F. Cell. 103:2000;321-330.
136. Polsky D., Bastian B.C., Hazan C., Melzer K., Pack J., Houghton A., Busam K., Cordon-Cardo C., Osman I. Cancer Res. 61:2001;7642-7646.
137. Landers J.E., Cassel S.L., George D.L. Cancer Res. 57:1997;3562-3568.
138. Gelsleichter L., Gown A.M., Zarbo R.J., Wang E., Coltrera M.D. Mod. Pathol. 8:1995;530-535.
139. Eliceiri B.P., Klemke R., Stromblad S., Cheresh D.A. J. Cell Biol. 140:1998;1255-1263.
140. Bonni A., Brunet A., West A.E., Datta S.R., Takasu M.A., Greenberg M.E. Science. 286:1999;1358-1362.
141. Erhardt P., Schremser E.J., Cooper G.M. Mol. Cell. Biol. 19:1999;5308-5315.
142. Woods D., Cherwinski H., Venetsanakos E., Bhat A., Gysin S., Humbert M., Bray P.F., Saylor V.L., McMahon M. Mol. Cell. Biol. 21:2001;3192-3205.
143. Albelda S.M., Mette S.A., Elder D.E., Stewart R., Damjanovich L., Herlyn M., Buck C.A. Cancer Res. 50:1990;6757-6764.
144. Klemke R.L., Cai S., Giannini A.L., Gallagher P.J., de Lanerolle P., Cheresh D.A. J. Cell Biol. 137:1997;481-492.
145. Herrera R., Sebolt-Leopold J.S. Trends Mol. Med. 8:2002;S27-S31.
146. Kolch W. Expert Opin. Pharmacother. 3:2002;709-718.
147. Hood J.D., Bednarski M., Frausto R., Guccione S., Reisfeld R.A., Xiang R., Cheresh D.A. Science. 296:2002;2404-2407.
148. Lackey K., Cory M., Davis R., Frye S.V., Harris P.A., Hunter R.N., Jung D.K., McDonald O.B., McNutt R.W., Peel M.R., Rutkowske R.D., Veal J.M., Wood E.R. Bioorg. Med. Chem. Lett. 10:2000;223-226.
149. Rudin C.M., Holmlund J., Fleming G.F., Mani S., Stadler W.M., Schumm P., Monia B.P., Johnston J.F., Geary R., Yu R.Z., Kwoh T.J., Dorr F.A., Ratain M.J. Clin. Cancer Res. 7:2001;1214-1220.
150. English J.M., Cobb M.H. Trends Pharmacol. Sci. 23:2002;40-45.
151. Sebolt-Leopold J.S. Oncogene. 19:2000;6594-6599.