Cell death by mitotic catastrophe: A molecular definition

Oncogene

Volumn 23, Issue 16 REV. ISS. 2, 2004, Pages 2825-2837

  Castedo, Maria ^a   Perfettini, Jean Luc ^a   Roumier, Thomas ^a   Andreau, Karine ^a   Medema, Rene ^b   Kroemer, Guido ^a  

^a INSTITUT GUSTAVE ROUSSY   (France)

^b NETHERLANDS CANCER INSTITUTE   (Netherlands)

Author keywords

Apoptosis; Bcl 2; Caspases; Cdk1; Chk2

Indexed keywords

1,3 BIS(2 FLUOROETHYL)NITROSOUREA; 7 HYDROXYSTAUROSPORINE; ANTINEOPLASTIC AGENT; APOPTOSIS INDUCING FACTOR; BENZYLOXYCARBONYLVALYLALANYLASPARTYL FLUOROMETHYL KETONE; CASEIN KINASE I; CASPASE 2; CASPASE 3; CASPASE 9; CELL CYCLE PROTEIN; CYCLIN B1; CYCLIN DEPENDENT KINASE 1; CYTOCHROME C; DEPSIPEPTIDE; DOXORUBICIN; FLUOROURACIL; IC 261; MACROGOL; NOCODAZOLE; OLOMOUCINE; OXAMFLATIN; PACLITAXEL; PHOSPHOTRANSFERASE; PHOSPHOTRANSFERASE INHIBITOR; PROTEIN BCL 2; PROTEIN P53; ROSCOVITINE; SURVIVIN; UNCLASSIFIED DRUG; VORINOSTAT; CHECKPOINT KINASE 2; CYCLIN B; PLX2 PROTEIN, XENOPUS; PROTEIN SERINE THREONINE KINASE; XENOPUS PROTEIN;

ANAPHASE; ANEUPLOIDY; APOPTOSIS; CARCINOGENESIS; CELL CYCLE; CELL DAMAGE; CELL DEATH; CELL DIVISION; CHROMOSOME ABERRATION; CHROMOSOME SEGREGATION; DNA DAMAGE; DNA STRUCTURE; ENZYME ACTIVATION; GENE MUTATION; HUMAN; LARGE CELL LYMPHOMA; MELANOMA; MEMBRANE PERMEABILITY; METAPHASE; MITOCHONDRIAL MEMBRANE; MITOSIS; MITOSIS SPINDLE; MORPHOLOGY; NONHUMAN; PRIORITY JOURNAL; REVIEW; ANIMAL; GENETICS; NEOPLASM; PATHOLOGY; PHYSIOLOGY; POLYPLOIDY;

ANIMALS; APOPTOSIS; CDC2 PROTEIN KINASE; CELL CYCLE PROTEINS; CYCLIN B; DNA DAMAGE; HUMANS; MITOSIS; NEOPLASMS; POLYPLOIDY; PROTEIN-SERINE-THREONINE KINASES; TUMOR SUPPRESSOR PROTEIN P53; XENOPUS PROTEINS;

EID: 2342635919     PISSN: 09509232     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.onc.1207528     Document Type: Review

References (158)

1. Allen JB, Zhou Z, Sied W, Friedberg EC and Elledge SJ. (1994). Genes Dev., 8, 2401-2415.
2. Altieri DC. (2003). Adv. Cancer Res., 88, 31-52.
3. Andreassen PR, Lacroix FB, Lohez OD and Margolis RL. (2001a). Cancer Res., 61, 7660-7668.
4. Andreassen PR, Lohez OD, Lacroix FB and Margolis RL. (2001b). Mol. Cell. Biol., 12, 1315-1328.
5. Ayscough K, Hayles J, MacNeill SA and Nurse P. (1992). Mol. Gen. Genet., 232, 344-350.
6. Baek KH, Yoo JK, Cho JH, Choi YH, Sung YC, McKeon F and Lee CW. (2003). J. Leukocyte Biol., 73, 850-861.
7. Behrend L, Milne DM, Stoter M, Deppert W, Campbell LE, Meek DW and Knippschild U. (2000). Oncogene, 19, 5303-5313.
8. Bell DW, Varley JM, Szydlo TE, Kang DH, Wahrer DC, Shannon KE, Lubratovich M, Verselis SJ, Isselbacher KJ, Fraumeni JF, Birch JM, Li FP, Garber JE and Haber DA. (1999). Science, 286, 2528-2531.
9. Blount PL, Galipeau PC, Sanchez CA, Neshat K, Levine DS, Yin J, Suzuki H, Abraham JM, Meltzer SJ and Reid BJ. (1994). Cancer Res., 54, 2292-2295.
10. Brinkley BR. (2001). Trends Cell Biol., 11, 18-21.
11. Bunz F, Dutriaux A, Lengauer C, Waldman T, Zhou S, Brown JP, Sedivy JM, Kinzler KW and Vogelstein B. (1998). Science, 282, 1497-1501.
12. Burke DJ. (2000). Curr. Opin. Genet. Dev., 10, 26-31.
13. Burns TF, Fei P, Scata KA, Dicker DT and El-Deiry WS. (2003). Mol. Cell. Biol., 23, 5556-5571.
14. Cahill DP, Lengauer C, Yu J, Riggins GJ, Willson JK, Markovitz SD, Kinzler KW and Vogelstein B. (1998). Nature, 392, 300-303.
15. Cande C, Cecconi F, Dessen P and Kroemer G. (2002). J. Cell Sci., 115, 4727-4734.
16. Carter BZ, Wang RY, Schober WD, Milella M, Chism D and Andreeff M. (2003). Cell Cycle, 2, 488-493.
17. Carvalho A, Carmena M, Sambade C, Earnshaw WC and Wheatley SP. (2003). J. Cell Sci., 116, 2987-2998.
18. Castedo M, Ferri KF, Blanco J, Roumier T, Larochette N, Barretina J, Amendola A, Nardacci R, Metivier D, Este JA, Piacentini M and Kroemer G. (2001). J. Exp. Med., 194, 1097-1110.
19. Castedo M, Perfettini J-L, Roumier T and Kroemer G. (2002a). Cell Death Differ., 9, 1287-1293.
20. Castedo M, Perfettini J-L, Roumier T, Valent A, Raslova H, Yakushijin K, Horne DA, Feunteun J, Lenoir G, Vainchenker W and Kroemer G. (2004a). Oncogene, (in press).
21. Castedo M, Perfettini J-L, Roumier T, Yakushijin K, Horne DA, Medema R and Kroemer G. (2004b). Oncogene, (in press).
22. Castedo M, Roumier T, Blanco J, Ferri KF, Barretina J, Andreau K, Perfettini J-L, Armendola A, Nardacci R, LeDuc P, Ingber DE, Este JA, Modjtahedi N, Piacentini M and Kroemer G. (2002b). EMBO J., 21, 4070-4080.
23. Chakrabarti A and Chakrabarti S. (1987). Neoplasma, 34, 557-562.
24. Chan TA, Hermeking H, Lengauer C, Kinzler KW and Vogelstein B. (1999). Nature, 401, 616-620.
25. Chehab NH, Malikzay A, Appel M and Halazonetis TD. (2000). Genes Dev., 14, 278-288.
26. Chen Z, Xiao Z, Chen J, Ng SC, Sowin T, Sham H, Rosenberg S, Fesik S and Zhang H. (2003). Mol. Cancer Ther., 2, 543-548.
27. Choma D, Daures JP, Quantin X and Pujol JL. (2001). Br. J. Cancer, 85, 14-22.
28. Clarke DJ, Segal M, Andrews CA, Rudyak SG, Jensen S, Smith K and Reed SI. (2003). Nat. Cell Biol., 5, 928-935.
29. Clarke DJ, Segal M, Mondesert G and Reed SI. (1999). Nat. Cell Biol., 3, 619-627.
30. Cogswell JP, Brown CE, Bisi JE and Neill SD. (2000). Cell Growth Differ., 11, 615-623.
31. Colombel M, Radvanyi F, Blanche M, Abbou C, Buttyan R, Donehower LA, Chopin D and Thiery JP. (1995). Oncogene, 10, 1269-1274.
32. Cutts SM, Fowler KJ, Kile BT, Hii LL, O'Dowd RA, Hudson DF, Saffery R, Kalitsis P, Earle E and Choo KH. (1999). Hum. Mol. Genet., 8, 1145-1155.
33. D'Assoro AB, Lingle WL and Salisbury JL. (2002). Oncogene, 21, 6146-6153.
34. Datta NS and Long MW. (2002). Exp. Hematol., 30, 158-165.
35. Deacon K, Mistry P, Chernoff J, Blank JL and Patel R. (2003). Mol. Cell. Biol., 14, 2071-2087.
36. Debatin KM, Poncet D and Kroemer G. (2002). Oncogene, 21, 8786-8803.
37. DeLuca JG, Moree B, Hickey JM, Kilmartin JV and Salmon ED. (2002). J. Cell Biol., 159, 549-555.
38. DeWitt N and Knight J. (2002). Nature, 416, 354.
39. Di Leonardo A, Khan SH, Linke SP, Greco V, Seidita G and Wahl GM. (1997). Cancer Res., 57, 1013-1019.
40. Driessens G, Harsan L, Robaye B, Waroquier D, Browaeys P, Giannakopoulos X, Velu T and Bruyns C. (2003). Br. J. Cancer, 18, 727-729.
41. Elez R, Piiper A, Kronenberger B, Kock M, Brendel M, Hermann E, Pliquett U, Neumann E and Zeuzem S. (2003). Oncogene, 22, 69-80.
42. Falck J, Maitland N, Syljuasen RG, Bartek J and Lukas J. (2000). Nature, 410, 842-847.
43. Ferri KF, Jacotot E, Blanco J, Esté JA, Zamzami A, Susin SA, Brothers G, Reed JC, Penninger JM and Kroemer G. (2000a). J. Exp. Med., 192, 1081-1092.
44. Ferri KF, Jacotot E, Geuskens M and Kroemer G. (2000b). Cell Death Differ., 7, 1137-1139.
45. Ferri KF and Kroemer G. (2001a). Nat. Cell Biol., 2, E63-E64.
46. Ferri KF and Kroemer GK. (2001b). Nat. Cell Biol., 3, E255-E263.
47. Fotedar R, Flatt J, Gupta S, Margolis RL, Fitzgerald P, Messier H and Fotedar A. (1995). Mol. Cell. Biol., 15, 932-942.
48. Geley S, Kramer E, Gieffers C, Gannon J, Peters JM and Hunt T. (2001). J. Cell Biol., 153, 137-148.
49. Gillet R, Grimber G, Bennoun M, Caron de Fromentel C, Briand P and Joulin V. (2000). Oncogene, 19, 3498-3507.
50. Gisselsson D. (2003). Adv. Cancer Res., 97, 1-29.
51. Green DR and Kroemer G. (1998). Trends Cell Biol., 8, 267-271.
52. Grossman D, Kim PJ, Blanc-Brude OP, Brash DE, Tognin S, Marchisio PC and Altieri DC. (2001). J. Clin. Invest., 108, 991-999.
53. Guo Y, Srinivasula SM, Druilhe A, Fernandes-Alnemri T and Alnemri ES. (2002). J. Biol. Chem., 277, 13430-13437.
54. Habu T, Kim SH, Weinstein J and Matsumoto M. (2002). EMBO J., 21, 6419-6428.
55. Hawkins DS, Demers GW and Galloway DA. (1996). Cancer Res., 56, 892-898.
56. Heald R, McLoughlin M and McKeon F. (1993). Cell, 74, 463-474.
57. Hofmann WK, Miller CW, Tsukasaki K, Tavor S, Ikezoe T, Hoelzer D, Takeuchi S and Koeffler HP. (2001). Leukemia Res., 25, 333-338.
58. Ianzini F and Mackey MA. (1997). Int. J. Radiat. Biol., 72, 409-421.
59. Ibrado AM, Kim CN and Bhalla K. (1998). Leukemia, 12, 1930-1936.
60. Iotsova V and Stehelin D. (1995). Eur. J. Cell Biol., 68, 122-132.
61. Ivanov A, Cragg MS, Erenpreisa J, Emzinsh D, Lukman H and Illidge TM. (2003). J. Cell Sci., 116, 4095-4106.
62. Jallepalli PV and Lengaue C. (2001). Nat. Rev. Cancer, 1, 109-117.
63. Jin P, Hardy S and Morgan DO. (1998). J. Cell Biol., 141, 875-885.
64. Joza N, Susin SA, Daugas E, Stanford WL, Cho SK, Li CYJ, Sasaki T, Elia AJ, Cheng H-YM, Ravagnan L, Ferri KF, Zamzami N, Wakeham A, Hakem R, Yoshida H, Kong Y-Y, Zuñiga-Pflücker JC, Kroemer G and Penninger JM. (2001). Nature, 410, 549-554.
65. Kerr JFR, Wyllie AH and Currie AR. (1972). Br. J. Cancer, 26, 239-257.
66. Konishi Y, Lehtinen M, Donovan N and Bonni A. (2002). Mol. Cell, 9, 1005-1016.
67. Kroemer G and Reed JC. (2000). Nat. Med., 6, 513-519.
68. Lanni JS and Jacks T. (1998). Mol. Cell. Biol., 18, 1055-1064.
69. Lassus P, Opitz-Araya X and Lazebnik Y. (2002). Science, 297, 1352-1354.
70. Lee J-S, Collin KM, Brown AL, Lee C-H and Chung JH. (2000). Nature, 404, 201-204.
71. Lens SM, Wolthuis RM, Klompmaker R, Kauw J, Agami R, Brummelkamp T, Kops G and Medema RH. (2003). EMBO J., 22, 2934-2947.
72. Letai A, Bassik M, Walensky L, Sorcinelli M, Weiler S and Korsmeyer S. (2002). Cancer Cell, 2, 183.
73. Li F, Ackermann EJ, Bennett CF, Rothermel AL, Plescia J, Tognin S, Villa A, Marchisio PC and Altieri DC. (1999). Nat. Cell Biol., 1, 461-466.
74. Li F, Ambrosini G, Chu EY, Plescia J, Tognin S, Marchisio PC and Altieri DC. (1998). Nature, 396, 580-584.
75. Lingle WL, Barrett SL, Negron VC, D'Assoro AB, Boeneman K, Liu W, Whitehead CM, Reynolds C and Salisbury JL. (2002). Proc. Natl. Acad. Sci. USA, 99, 1978-1983.
76. Liu X and Erikson RL. (2003). Proc. Natl. Acad. Sci. USA, 100, 5789-5794.
77. Lock RB and Stribinskiene L. (1996). Cancer Res., 56, 4006-4012.
78. Mantel C, Braun SE, Reid S, Henegariu O, Liu L, Hangoc G and Broxmeyer HE. (1999). Blood, 93, 1390-1398.
79. Margottin-Goguet F, Hsu JY, Loktev A, Hsieh H-M, Reimann JDR and Jackson PK. (2003). Dev. Cell, 4, 813-826.
80. Masuda A and Takahashi T. (2002a). Oncogene, 21, 6884-6897.
81. Masuda A and Takahashi T. (2002b). Oncogene, 21, 6884-6897.
82. Meijers-Heijboe H, van den Ouweland A, Klijn J, Wasielewski M, de Snoo A, Oldenburg R, Hollestelle A, Houben M, Crepin E, van Veghel-Plandsoen M, Elstrodt F, van Duijn C, Bartels C, Meijers C, Schutte M, McGuffog L, Thompson D, Easton D, Sodha N, Seal S, Barfoot R, Mangion J, Chang-Claude J, Eccles D, Eeles R, Evans DG, Houlston R, Murday V, Narod S, Peretz T, Peto J, Phelan C, Zhang HX, Szabo C, Devilee P, Goldgar D, Futreal PA, Nathanson KL, Weber B, Rahman N and Stratton MR. (2002). Nat. Genet., 31, 55-59.
83. Melo J and Toczyski D. (2002). Curr. Opin. Cell Biol., 14, 237-245.
84. Meraldi P, Honda R and Nigg EA. (2002). EMBO J., 21, 483-492.
85. Miller CW, Ikezoe T, Krug U, Hofmann WK, Tavor S, Vegesna V, Tsukasaki K, Takeuchi S and Koeffler HP. (2002). Genes Chromosomes Cancer, 33, 17-21.
86. Minn AJ, Boise LH and Thompson CB. (1996). Genes Dev., 10, 2621-2631.
87. Molz L, Boohe R, Young P and Beach D. (1989). Genetics, 773-782.
88. Nabha SM, Mohammad RM, Dandashi MH, Coupaye-Gerard B, Aboukameel A, Pettit GR and Al-Katib AM. (2002). Clin. Cancer Res., 8, 2735-2741.
89. Nigg EA. (2001). Nat. Rev. Mol. Cell. Biol., 2, 21-32.
90. Nitta M, Tsuiki H, Arima Y, Harada K, Nishizaki T, Sasaki K, Mimori T, Ushio Y and Saya H. (2003). Genes Cells, 7, 151-162.
91. Notterman D, Young S, Wainger B and Levine AJ. (1998). Oncogene, 17, 2743-2751.
92. O'Connor DS, Wall NR, Porter AC and Altieri DC. (2002). Cancer Cell, 2, 43-54.
93. Oberringer M, Lothschutz D, Jennewein M, Koschnick M, Mutschler W and Hanselmann RG. (1999). Mol. Cell. Biol. Res. Commun., 2, 190-196.
94. Paroni G, Henderson C, Schneider C and Brancolini C. (2002). J. Biol. Chem., 277, 15147-15161.
95. Peart MJ, Tainton KM, Ruefli AA, Dear AE, Sedelies KA, O'Reilly LA, Waterhouse NJ, Trapani JA and Johnstone RW. (2003). Cancer Res., 63, 4460-4471.
96. Peng C-Y, Graves PR, Thoma RS, Wu Z, Shaw AS and Piwnica-Worms H. (1997). Science, 277, 1501-1505.
97. Penninger JM and Kroemer G. (2003). Nat. Cell Biol., 5, 97-99.
98. Perfettini J-L, Roumier T, Castedo M, Larochette N, Boya P, Reynal B, Lazar V, Ciccosanti F, Nardacci R, Penninger JM, Piacentini M and Kroemer G. (2004). J. Exp. Med., 199, 620-640.
99. Peters JM. (2002). Mol. Cell, 9, 931-943.
100. Porter LA, Cukier IH and Lee JM. (2003). Blood, 101, 1928-1933.
101. Ramel S, Sanchez CA, Schimke MK, Neshat K, Cross SM, Raskind WH and Reid BJ. (1995). Pancreas, 11, 213-222.
102. Raslova H, Roy L, Vourch C, Lecouedic JP, Brison O, Metivier D, Feunteun J, Kroemer G, Debili N and Vainchenker W. (2003). Blood, 101, 541-544.
103. Read SH, Baliga BC, Ekert PG, Vaux DL and Kumar S. (2002). J. Cell Biol., 159, 739-745.
104. Robertson JD, Enoksson M, Suomela M, Zhivotovsky B and Orrenius S. (2002). J. Biol. Chem., 277, 29803-29809.
105. Roninson IB, Broude EV and Chang B-D. (2001). Drug Resistance Updates, 4, 303-313.
106. Rotter V, Schartz D, Almon E, Goldfinger N, Kapon A, Meshorer A, Donehower LA and Levine AJ. (1993). Proc. Natl. Acad. Sci. USA, 90, 9075-9079.
107. Roumier T, Castedo M, Perfettini J-L, Andreau K, Metivier D, Zamzami N and Kroemer G. (2003). Biochem. Pharmacol., 66.
108. Ruth AC and Roninson IB. (2000). Cancer Res., 60, 2576-2578.
109. Sato N, Mizumoto K, Nakamura M and Tanaka M. (2000). Exp. Cell Res., 255, 321-326.
110. Sen S, Zhou H, Zhan RD, Yoon DS, Vakar-Lopez F, Ito S, Jiang F, Johnston D, Grossman HB, Ruifrok AC, Katz RL, Brinkley W and Czerniak B. (2002). J. Natl. Cancer Inst., 94, 1320-1329.
111. Senderowicz AM. (2003). Cancer Chemother. Pharmacol., 52, S61-S73.
112. Seo GJ, Kim SE, Lee YM, Lee JW, Lee JR, Hahn MJ and Kim ST. (2003). Biochem. Biophys. Res. Commun., 304, 339-343.
113. Shah JV and Cleveland DW. (2000). Cell, 103, 997-1000.
114. Shankar SL, Mani S, O'Guin KN, Kandimalla ER, Agrawal S and Shafit-Zagardo B. (2001). J. Neurochem., 79, 426-436.
115. Sheih SY, Ahn J, Tamai K, Taya Y and Prives C. (2000). Genes Dev., 14, 289-300.
116. Shih I-M, Zhou W, Goodman SN, Lengauer CL, Kinzler KW and Vogelstein B. (2001). Cancer Res., 61, 818-822.
117. Shin DM, Charuruks N, Lippman SM, Lee JJ, Ro JY, Hong WK and Hittelman WN. (2001). Cancer Epidemiol. Biomarkers Prev., 10, 603-609.
118. Slovak ML, Kopecky KJ, Cassileth PA, Harrington DH, Theil KS, Mohamed A, Paietta E, Willman CL, Head DR, Rowe JM, Forman SJ and Appelbaum FR. (2000). Blood, 96, 4075-4083.
119. Smits VA and Medema RH. (2001). Biochim. Biophys. Acta, 1519, 1-12.
120. Song Z, Yao X and Wu M. (2003). J. Biol. Chem., 278, 23130-23140.
121. Spankuch-Schmitt B, Wolf G, Solbach C, Loibl S, Knecht R, Stegmuller M, von Minckwitz G, Kaufmann M and Strebhardt K. (2002). Oncogene, 21, 3162-3171.
122. Sperling K and Ra PN. (1974). Chromosoma, 14, 121-131.
123. Stevens C, Smith L and La Thangue NB. (2003). Nat. Cell Biol., 5, 401-409.
124. Strathdee G, Sansom OJ, Sim A, Clarke AR and Brown R. (2001). Oncogene, 20, 1923-1927.
125. Susin SA, Daugas E, Ravagnan L, Samejima K, Zamzami N, Loeffler M, Costantini P, Ferri KF, Irinopoulou T, Prévost M-C, Brothers G, Mak TW, Penninger J, Earnshaw WC and Kroemer G. (2000). J. Exp. Med., 192, 571-579.
126. Susin SA, Lorenzo HK, Zamzami N, Marzo I, Snow BE, Brothers GM, Mangion J, Jacotot E, Costantini P, Loeffler M, Larochette N, Goodlett DR, Aebersold R, Siderovski DP, Penninger JM and Kroemer G. (1999). Nature, 397, 441-446.
127. Swanson PE, Carroll SB, Zhang XF and Mackey MA. (1995). Am. J. Pathol., 146, 963-971.
128. Takada S, Kelkar A and Theurkauf WE. (2003). Cell, 113, 87-99.
129. Taylor WR, DePrimo SE, Agarwal A, Agarwal ML, Schonthal AH, Katula KS and Stark GR. (1999). Mol. Cell. Biol., 10, 3607-3622.
130. Taylor WR and Stark GR. (2001). Oncogene, 20, 1803-1815.
131. Terada N, Hamazaki T, Oka M, Hoki M, Mastalerz DM, Nakano Y, Meyer EM, Morel L, Petersen BE and Scott EW. (2002). Nature, 416, 542-545.
132. Tort F, Hernandez S, Bea S, Martinez A, Estller M, Herman JG, Puig X, Camacho E, Sanchez M, Nayach I, Lopez-Guillermo A, Fernandez PL, Colomer D, Hernandez L and Campo E. (2003). Blood, 100.
133. Tsuiki H, Nitta M, Tada M, Inagaki M, Ushio Y and Saya H. (2001). Oncogene, 20, 420-429.
134. Tsvetkov L, Xu X, Li J and Stern DF. (2003). J. Biol. Chem., 278, 8468-8475.
135. Uren AG, Wong L, Pakusch M, Fowler KJ, Burrows FJ, Vaux DL and Choo KH. (2000). Curr. Biol., 10, 1319-1328.
136. Vahteristo P, Bartkova J, Eerola H, Syrjakoski K, Ojala S, Kilpivaara O, Tamminen A, Kononen J, Aittomaki K, Heikkila P, Holli K, Blomqvist C, Bartek J, Kallioniemi OP and Nevanlinna H. (2002). Am. J. Hum. Genet., 71, 432-438.
137. Vassilopoulos G, Wang PR and Russell DW. (2003). Nature, 422, 901-904.
138. Verdecia MA, Huang H, Dutil E, Kaiser DA, Hunter T and Noel JP. (2000). Nat. Struct. Biol., 7, 602-608.
139. Verdoodt B, Decordier I, Geleyns K, Cunha M, Cundari E and Kirsch-Volders M. (1999). Mutagenesis, 14, 513-520.
140. Verschuren EW, Klefstrom J, Evan GI and Jones N. (2002). Cancer Cell, 2, 229-241.
141. Vikhanskaya F, Vignati S, Beccaglia P, Ottoboni C, Russo P, D'Incalci M and Broggini M. (1998). Exp. Cell Res., 241, 96-101.
142. Wahl AF, Donaldson KL, Fairchild C, Lee FY, Foster SA, Demers GW and Galloway DA. (1996). Nat. Med., 2, 72-79.
143. Wall NR, O'Connor DS, Plescia J, Pommier Y and Altieri DC. (2003). Cancer Res., 63, 230-235.
144. Wang Q, Xie S, Chen J, Fukasawa K, Naik U, Traganos F, Darzynkiewicz Z, Jhanwar-Uniyal M and Dai W. (2002). Mol. Cell. Biol., 22, 3450-3459.
145. Weinert TA, Kiser GL and Hartwell LH. (1994). Genes Dev., 8, 652-665.
146. Wu GW, Nutt CL, Zlatescu MC, Keeney M, Chin-Yee I and Cairncross JG. (2001a). Cancer Res., 61, 4155-4159.
147. Wu X, Webster SR and Chen J. (2001b). J. Biol. Chem., 276, 2971-2974.
148. Wurmser AE and Gage FH. (2002). Nature, 416, 485-487.
149. Xu J and Du W. (2003). FEBS Lett., 19, 209-212.
150. Yang S, Kuo C, Bisi JE and Kim MK. (2002). Nat. Cell Biol., 4, 865-870.
151. Yin XY, Grove L, Datta NS, Long MW and Prochownik EV. (1999). Oncogene, 18, 1177-1184.
152. Yoshikawa R, Kusunoki M, Yanagi H, Noda M, Furuyama JI, Yamamura T and Hashimoto-Tamaoki T. (2001). Cancer Res., 61, 1029-1037.
153. Yu H. (2002). Curr. Opin. Cell Biol., 14, 706-714.
154. Yu Q, La Rose J, Zhang H, Takemura H, Kohn KW and Pommier Y. (2002). Cancer Res., 62, 5743-5748.
155. Yuan J, Kramer A, Eckerdt F, Kaufmann M and Strebhardt K. (2002). Cancer Res., 62, 4186-4190.
156. Yun J, Chae HD, Choy HE, Chung J, Yoo HS, Han MH and Shin DY. (1999). J. Biol. Chem., 274, 29677-29682.
157. Zamzami N, Brenner C, Marzo I, Susin SA and Kroemer G. (1998). Oncogene, 16, 2265-2282.
158. Zamzami N and Kroemer G. (2003). Curr. Biol., 13, R71-R73.