-
1
-
-
0032749652
-
Estimates of the worldwide mortality from 25 cancers in 1990
-
Pisani, P., Parkin, D. M., Bray, F. & Ferlay, J. Estimates of the worldwide mortality from 25 cancers in 1990. Int. J. Cancer 83, 870-873 (1999).
-
(1999)
Int. J. Cancer
, vol.83
, pp. 870-873
-
-
Pisani, P.1
Parkin, D.M.2
Bray, F.3
Ferlay, J.4
-
2
-
-
0003452109
-
-
(eds Potter, J. D. et al.) (World Cancer Research Fund/American Institute for Cancer Research)
-
Food, Nutrition and the Prevention of Cancer: a Global Perspective (eds Potter, J. D. et al.) (World Cancer Research Fund/American Institute for Cancer Research, 1997).
-
(1997)
Food, Nutrition and the Prevention of Cancer: A Global Perspective
-
-
-
3
-
-
0036370334
-
Helicobacter pylori and gastrointestinal tract adenocarcinomas
-
Peek R. M. Jr & Blaser, M. J. Helicobacter pylori and gastrointestinal tract adenocarcinomas. Nature Rev. Cancer 2, 28-37 (2002).
-
(2002)
Nature Rev. Cancer
, vol.2
, pp. 28-37
-
-
Peek R.M., Jr.1
Blaser, M.J.2
-
4
-
-
0031802252
-
Meta-analysis of the relationship between Helicobacter pylori seropositivity and gastric cancer
-
Huang, J. Q., Sridhar, S., Chen, Y. & Hunt, R. H. Meta-analysis of the relationship between Helicobacter pylori seropositivity and gastric cancer. Gastroenterology 114, 1169-1179 (1998). Meta-analysis of the relationship between H. pylori infection and gastric cancer shows that infection with these bacteria is equally associated with the intestinal or diffuse types of gastric cancer.
-
(1998)
Gastroenterology
, vol.114
, pp. 1169-1179
-
-
Huang, J.Q.1
Sridhar, S.2
Chen, Y.3
Hunt, R.H.4
-
5
-
-
12644292106
-
The two histological main types of gastric carcinoma: Diffuse and so-called intestinal-type carcinoma
-
Lauren, P. The two histological main types of gastric carcinoma: diffuse and so-called intestinal-type carcinoma. Acta Pathol. Microbiol. Scand. 64, 31-49 (1965).
-
(1965)
Acta Pathol. Microbiol. Scand.
, vol.64
, pp. 31-49
-
-
Lauren, P.1
-
6
-
-
0027065034
-
Human gastric carcinogenesis: A multistep and multifactorial process - First American Cancer Society Award Lecture on Cancer Epidemiology and Prevention
-
Correa, P. Human gastric carcinogenesis: a multistep and multifactorial process - First American Cancer Society Award Lecture on Cancer Epidemiology and Prevention Cancer Res. 52, 6735-6740 (1992).
-
(1992)
Cancer Res.
, vol.52
, pp. 6735-6740
-
-
Correa, P.1
-
7
-
-
0036782277
-
Deregulated homeobox gene expression in cancer: Cause or consequence?
-
Abate-Shen, C. Deregulated homeobox gene expression in cancer: cause or consequence? Nature Rev. Cancer 2, 777-785 (2002). Proposes that homeobox genes can be defined as tumour modulators rather than as oncogenes or tumour suppressors, based on deregulated gene expression in cancer.
-
(2002)
Nature Rev. Cancer
, vol.2
, pp. 777-785
-
-
Abate-Shen, C.1
-
8
-
-
0034161299
-
Endoderm development: From patterning to organogenesis
-
Grapin-Botton, A. & Melton D. A. Endoderm development: from patterning to organogenesis. Trends Genet. 16, 124-130 (2000).
-
(2000)
Trends Genet.
, vol.16
, pp. 124-130
-
-
Grapin-Botton, A.1
Melton, D.A.2
-
9
-
-
0030916211
-
GATA 4 transcription factor is required for ventral morphogenesis and heart tube formation
-
Kuo, C. T. et al. GATA4 transcription factor is required for ventral morphogenesis and heart tube formation. Genes Dev. 11, 1048-1060 (1997).
-
(1997)
Genes Dev.
, vol.11
, pp. 1048-1060
-
-
Kuo, C.T.1
-
10
-
-
0030996908
-
Requirement of the transcription factor GATA 4 for heart tube formation and ventral morphogenesis
-
Molkentin, J. D., Lin, Q., Duncan, S. A. & Olson, E. N. Requirement of the transcription factor GATA4 for heart tube formation and ventral morphogenesis. Genes Dev. 11, 1061-1072 (1997).
-
(1997)
Genes Dev.
, vol.11
, pp. 1061-1072
-
-
Molkentin, J.D.1
Lin, Q.2
Duncan, S.A.3
Olson, E.N.4
-
11
-
-
0032915460
-
Early embryonic lethality in Bmp5; Bmp 7 double mutant mice suggests functional redundancy within the 60A subgroup
-
Solloway, M. J. & Robertson, E. J. Early embryonic lethality in Bmp5; Bmp7 double mutant mice suggests functional redundancy within the 60A subgroup. Development 126, 1753-1768 (1999).
-
(1999)
Development
, vol.126
, pp. 1753-1768
-
-
Solloway, M.J.1
Robertson, E.J.2
-
12
-
-
0034061209
-
Homeobox genes and gut development
-
Beck, F., Tata, F. & Chawengsaksophak, K. Homeobox genes and gut development. Bioessays 22, 431-441 (2000).
-
(2000)
Bioessays
, vol.22
, pp. 431-441
-
-
Beck, F.1
Tata, F.2
Chawengsaksophak, K.3
-
13
-
-
0036159690
-
Region-specific gastrointestinal Hox code during murine embryonal gut development
-
Kawazoe, Y. et al. Region-specific gastrointestinal Hox code during murine embryonal gut development. Dev Growth Differ. 44, 77-84 (2002).
-
(2002)
Dev Growth Differ.
, vol.44
, pp. 77-84
-
-
Kawazoe, Y.1
-
14
-
-
0028875032
-
Sonic hedgehog is an endodermal signal inducing Bmp- 4 and Hox genes during induction and regionalization of the chick hindgut
-
Roberts, D. J. et al. Sonic hedgehog is an endodermal signal inducing Bmp-4 and Hox genes during induction and regionalization of the chick hindgut. Development 121, 3163-3174 (1995).
-
(1995)
Development
, vol.121
, pp. 3163-3174
-
-
Roberts, D.J.1
-
15
-
-
0031661708
-
Epithelial-mesenchymal signaling during the regionalization of the chick gut
-
Roberts, D. J., Smith, D. M., Goff, D. J. & Tabin, C. J. Epithelial-mesenchymal signaling during the regionalization of the chick gut. Development 125, 2791-2801 (1998).
-
(1998)
Development
, vol.125
, pp. 2791-2801
-
-
Roberts, D.J.1
Smith, D.M.2
Goff, D.J.3
Tabin, C.J.4
-
16
-
-
0033769822
-
Cdx 1 and Cdx2 expression during intestinal development
-
Silberg, D. G., Swain, G. P., Suh, E. R. & Traber, P. G. Cdx1 and Cdx2 expression during intestinal development. Gastroenterology 119, 961-971 (2000).
-
(2000)
Gastroenterology
, vol.119
, pp. 961-971
-
-
Silberg, D.G.1
Swain, G.P.2
Suh, E.R.3
Traber, P.G.4
-
17
-
-
0029868156
-
PDX- 1 is required for pancreatic outgrowth and differentiation of the rostral duodenum
-
Offield, M. F. et al. PDX-1 is required for pancreatic outgrowth and differentiation of the rostral duodenum. Development 122, 983-995 (1996).
-
(1996)
Development
, vol.122
, pp. 983-995
-
-
Offield, M.F.1
-
18
-
-
0030937750
-
Homeosis and intestinal tumours in Cdx2 mutant mice
-
Chawengsaksophak, K., James, R., Hammond, V. E., Kontgen, F. & Beck, F. Homeosis and intestinal tumours in Cdx2 mutant mice. Nature 386, 84-87 (1997). Mice with heterozygous disruptions in Cdx2 develop many colonic polyps, indicating a tumour-suppressive activity of Cdx2.
-
(1997)
Nature
, vol.386
, pp. 84-87
-
-
Chawengsaksophak, K.1
James, R.2
Hammond, V.E.3
Kontgen, F.4
Beck, F.5
-
19
-
-
0033594940
-
Reprogramming of intestinal differentiation and intercalary regeneration in Cdx 2 mutant mice
-
Beck, F., Chawengsaksophak, K,. Waring, P., Playford, R. J. & Furness, J. B. Reprogramming of intestinal differentiation and intercalary regeneration in Cdx2 mutant mice. Proc. Natl Acad. Sci. USA 96, 7318-7323 (1999).
-
(1999)
Proc. Natl. Acad. Sci. USA
, vol.96
, pp. 7318-7323
-
-
Beck, F.1
Chawengsaksophak, K.2
Waring, P.3
Playford, R.J.4
Furness, J.B.5
-
20
-
-
0031440118
-
Key role of the Cdx2 homeobox gene in extracellular matrix-mediated intestinal cell differentiation
-
Lorentz, O. et al. Key role of the Cdx2 homeobox gene in extracellular matrix-mediated intestinal cell differentiation. J. Cell Biol. 139, 1553-1565 (1997).
-
(1997)
J. Cell Biol.
, vol.139
, pp. 1553-1565
-
-
Lorentz, O.1
-
21
-
-
0031672472
-
Transducing positional information to the Hox genes: Critical interaction of Cdx gene products with position-sensitive regulatory elements
-
Charite, J. et al. Transducing positional information to the Hox genes: critical interaction of Cdx gene products with position-sensitive regulatory elements. Development 125, 4349-4358 (1998).
-
(1998)
Development
, vol.125
, pp. 4349-4358
-
-
Charite, J.1
-
22
-
-
0028800024
-
Disruption of the murine homeobox gene Cdx 1 affects axial skeletal identities by altering the mesodermal expression domains of Hox genes
-
Subramanian, V., Meyer, B. I. & Gruss, P. Disruption of the murine homeobox gene Cdx1 affects axial skeletal identities by altering the mesodermal expression domains of Hox genes. Cell 83, 641-653 (1995).
-
(1995)
Cell
, vol.83
, pp. 641-653
-
-
Subramanian, V.1
Meyer, B.I.2
Gruss, P.3
-
23
-
-
0028149890
-
Insulin-promoter-factor 1 is required for pancreas development in mice
-
Jonsson, J., Carlsson, L., Edlund, T. & Edlund, H. Insulin-promoter-factor 1 is required for pancreas development in mice. Nature 371, 606-609 (1994).
-
(1994)
Nature
, vol.371
, pp. 606-609
-
-
Jonsson, J.1
Carlsson, L.2
Edlund, T.3
Edlund, H.4
-
24
-
-
0034960799
-
Expression patterns of Wnt genes in mouse gut development
-
Lickert, H., Kispert, A., Kutsch, S. & Kemler, R. Expression patterns of Wnt genes in mouse gut development. Mech. Dev. 105, 181-184 (2001).
-
(2001)
Mech. Dev.
, vol.105
, pp. 181-184
-
-
Lickert, H.1
Kispert, A.2
Kutsch, S.3
Kemler, R.4
-
25
-
-
0345039872
-
Wnt signaling components in the chicken intestinal tract
-
McBride, H. J., Fatke, B. & Fraser, S. E. Wnt signaling components in the chicken intestinal tract. Dev. Biol. 256, 18-33 (2003).
-
(2003)
Dev. Biol.
, vol.256
, pp. 18-33
-
-
McBride, H.J.1
Fatke, B.2
Fraser, S.E.3
-
26
-
-
0034093614
-
Early mouse endoderm is patterned by soluble factors from adjacent germ layers
-
Wells, J. M. & Melton, D. A. Early mouse endoderm is patterned by soluble factors from adjacent germ layers. Development 127, 1563-1572 (2000).
-
(2000)
Development
, vol.127
, pp. 1563-1572
-
-
Wells, J.M.1
Melton, D.A.2
-
27
-
-
0031758247
-
Region-specific expression of chicken Sox2 in the developing gut and lung epithelium: Regulation by epithelial-mesenchymal interactions
-
Ishii, Y., Rex, M., Scotting, P. J. & Yasugi, S. Region-specific expression of chicken Sox2 in the developing gut and lung epithelium: regulation by epithelial-mesenchymal interactions. Dev. Dyn. 213, 464-475 (1998).
-
(1998)
Dev. Dyn.
, vol.213
, pp. 464-475
-
-
Ishii, Y.1
Rex, M.2
Scotting, P.J.3
Yasugi, S.4
-
28
-
-
0029074587
-
Epithelial immaturity and multiorgan failure in mice lacking epidermal growth factor receptor
-
Miettinen, P. J. et al. Epithelial immaturity and multiorgan failure in mice lacking epidermal growth factor receptor. Nature 376, 337-341 (1995).
-
(1995)
Nature
, vol.376
, pp. 337-341
-
-
Miettinen, P.J.1
-
29
-
-
0032974961
-
Targeted disruption of the homeobox transcription factor Nkx2- 3 in mice results in postnatal lethality and abnormal development of small intestine and spleen
-
Pabst, O., Zweigerdt, R, & Arnold, H, H. Targeted disruption of the homeobox transcription factor Nkx2-3 in mice results in postnatal lethality and abnormal development of small intestine and spleen. Development 126, 2215-2225 (1999).
-
(1999)
Development
, vol.126
, pp. 2215-2225
-
-
Pabst, O.1
Zweigerdt, R.2
Arnold, H.H.3
-
30
-
-
0034235484
-
Role for cGATA-5 in transcriptional regulation of the embryonic chicken pepsinogen gene by epithelial-mesenchymal interactions in the developing chicken stomach
-
Sakamoto, N. et al. Role for cGATA-5 in transcriptional regulation of the embryonic chicken pepsinogen gene by epithelial-mesenchymal interactions in the developing chicken stomach Dev. Biol. 223, 103-113 (2000).
-
(2000)
Dev. Biol.
, vol.223
, pp. 103-113
-
-
Sakamoto, N.1
-
31
-
-
0030920026
-
Transcriptional activation of H+/K+-ATPase genes by gastric GATA binding proteins
-
Nishi, T., Kubo, K., Hasebe, M., Maeda, M. & Futai, M. Transcriptional activation of H+/K+-ATPase genes by gastric GATA binding proteins. J. Biochem. 121, 922-929 (1997).
-
(1997)
J. Biochem.
, vol.121
, pp. 922-929
-
-
Nishi, T.1
Kubo, K.2
Hasebe, M.3
Maeda, M.4
Futai, M.5
-
32
-
-
0036149471
-
Genetic mosaic analysis reveals that GATA- 4 is required for proper differentiation of mouse gastric epithelium
-
Jacobsen, C. M. et al. Genetic mosaic analysis reveals that GATA-4 is required for proper differentiation of mouse gastric epithelium. Dev. Biol. 241, 34-46 (2002).
-
(2002)
Dev. Biol.
, vol.241
, pp. 34-46
-
-
Jacobsen, C.M.1
-
33
-
-
0030448129
-
Pancreatic-duodenal homeobox 1: Role in gastric endocrine patterning
-
Larsson, L. I., Madsen, O. D., Serup, P., Jonsson, J. & Edlund, H. Pancreatic-duodenal homeobox 1: role in gastric endocrine patterning. Mech. Dev. 60, 175-184 (1996).
-
(1996)
Mech. Dev.
, vol.60
, pp. 175-184
-
-
Larsson, L.I.1
Madsen, O.D.2
Serup, P.3
Jonsson, J.4
Edlund, H.5
-
34
-
-
0032321929
-
The Cdx-1 and Cdx- 2 homeobox genes in the intestine
-
Freund, J. N., Domon-Dell, C., Kedinger, M. & Duluc, I. The Cdx-1 and Cdx-2 homeobox genes in the intestine. Biochem. Cell Biol. 76, 957-969 (1998).
-
(1998)
Biochem. Cell Biol.
, vol.76
, pp. 957-969
-
-
Freund, J.N.1
Domon-Dell, C.2
Kedinger, M.3
Duluc, I.4
-
35
-
-
0037462878
-
Homeodomain protein CDX 2 regulates goblet specific MUC2 gene expression
-
Yamamoto, H., Bai, Y.-Q. & Yuasa, Y. Homeodomain protein CDX2 regulates goblet specific MUC2 gene expression. Biochem. Biophys. Res. Commun. 300, 813-818 (2003).
-
(2003)
Biochem. Biophys. Res. Commun.
, vol.300
, pp. 813-818
-
-
Yamamoto, H.1
Bai, Y.-Q.2
Yuasa, Y.3
-
36
-
-
0036829210
-
CDX2 regulates liver intestine-cadherin expression in normal and malignant colon epithelium and intestinal metaplasia
-
Hinoi, T. et al. CDX2 regulates liver intestine-cadherin expression in normal and malignant colon epithelium and intestinal metaplasia. Gastroenterology 122, 1565-1577 (2002).
-
(2002)
Gastroenterology
, vol.122
, pp. 1565-1577
-
-
Hinoi, T.1
-
37
-
-
18544404101
-
Control of endodermal endocrine development by Hes-1
-
Jensen, J. et al Control of endodermal endocrine development by Hes-1. Nature Genet. 24, 36-44 (2000)
-
(2000)
Nature Genet.
, vol.24
, pp. 36-44
-
-
Jensen, J.1
-
38
-
-
0035824487
-
Requirement of Math 1 for secretory cell lineage commitment in the mouse intestine
-
Yang, Q., Bermingham, N. A. Finegold, M. J. & Zoghbi, H. Y. Requirement of Math1 for secretory cell lineage commitment in the mouse intestine. Science 294, 2155-2158 (2001).
-
(2001)
Science
, vol.294
, pp. 2155-2158
-
-
Yang, Q.1
Bermingham, N.A.2
Finegold, M.J.3
Zoghbi, H.Y.4
-
39
-
-
0034878894
-
Helicobacter and Cancer Collaborative Group. Gastric cancer and Helicobacter pylori: A combined analysis of 12 case control studies nested within prospective cohorts
-
Helicobacter and Cancer Collaborative Group. Gastric cancer and Helicobacter pylori: a combined analysis of 12 case control studies nested within prospective cohorts. Gut 49, 347-353 (2001).
-
(2001)
Gut
, vol.49
, pp. 347-353
-
-
-
40
-
-
0037169076
-
SHP-2 tyrosine phosphatase as an intracellular target of Helicobacter pylori CagA protein
-
Higashi, H. et al. SHP-2 tyrosine phosphatase as an intracellular target of Helicobacter pylori CagA protein. Science 295, 683-686 (2002).
-
(2002)
Science
, vol.295
, pp. 683-686
-
-
Higashi, H.1
-
41
-
-
0038352053
-
Radical causes of cancer
-
Hussain, S. P., Hofseth, L. J. & Harris, C. C. Radical causes of cancer. Nature Rev. Cancer 3, 276-285 (2003).
-
(2003)
Nature Rev. Cancer
, vol.3
, pp. 276-285
-
-
Hussain, S.P.1
Hofseth, L.J.2
Harris, C.C.3
-
42
-
-
0034704880
-
Interleukin-1 polymorphisms associated with increased risk of gastric cancer
-
El-Omar, E. M. et al. Interleukin-1 polymorphisms associated with increased risk of gastric cancer. Nature 404, 398-402 (2000). Shows that the IL-1β polymorphism can determine why some individuals infected with H. pylori develop gastric cancer but others do not.
-
(2000)
Nature
, vol.404
, pp. 398-402
-
-
El-Omar, E.M.1
-
43
-
-
85047656659
-
CDX2, a homeobox transcription factor up-regulates transcription of the p21/WAF1/CIP1 gene
-
in the press
-
Bai, Y.-Q., Miyake, S., Iwai, T. & Yuasa, Y. CDX2, a homeobox transcription factor up-regulates transcription of the p21/WAF1/CIP1 gene. Oncogene (in the press).
-
Oncogene
-
-
Bai, Y.-Q.1
Miyake, S.2
Iwai, T.3
Yuasa, Y.4
-
44
-
-
18244362326
-
Ectopic expression of homeodomain protein CDX2 in intestinal metaplasia and carcinomas of the stomach
-
Bai, Y.-Q. et al. Ectopic expression of homeodomain protein CDX2 in intestinal metaplasia and carcinomas of the stomach. Cancer Lett. 176, 47-55 (2002). The expression of the intestine-specific homeoprotein CDX2 was found in intestinal metaplasia and carcinomas of the stomach, indicating its involvement in these lesions.
-
(2002)
Cancer Lett.
, vol.176
, pp. 47-55
-
-
Bai, Y.-Q.1
-
45
-
-
0036180974
-
Cdx2 ectopic expression induces gastric intestinal metaplasia in transgenic mice
-
Silberg, D. G. et al. Cdx2 ectopic expression induces gastric intestinal metaplasia in transgenic mice. Gastroenterology 122, 689-696 (2002). Cdx2 ectopic expression in the stomach induces intestinal metaplasia in transgenic mice, showing that Cdx2 is involved in the initiation of intestinal metaplasia formation.
-
(2002)
Gastroenterology
, vol.122
, pp. 689-696
-
-
Silberg, D.G.1
-
46
-
-
0030955272
-
Early specification of intestinal epithelium in the chicken embryo: A study on the localization and regulation of CdxA expression
-
Ishii, Y., Fukuda, K., Saiga, H., Matsushita, S. & Yasugi, S. Early specification of intestinal epithelium in the chicken embryo: a study on the localization and regulation of CdxA expression. Dev. Growth Differ. 39, 643-653 (1997).
-
(1997)
Dev. Growth Differ.
, vol.39
, pp. 643-653
-
-
Ishii, Y.1
Fukuda, K.2
Saiga, H.3
Matsushita, S.4
Yasugi, S.5
-
47
-
-
0033607763
-
Cell type-specific autoregulation of the caudal-related homeobox gene Cdx-2/3
-
Xu, F., Li, H. & Jin, T. Cell type-specific autoregulation of the caudal-related homeobox gene Cdx-2/3. J. Biol. Chem. 274, 34310-34316 (1999).
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 34310-34316
-
-
Xu, F.1
Li, H.2
Jin, T.3
-
48
-
-
0030795415
-
CDX1 protein expression in normal, metaplastic, and neoplastic human alimentary tract epithelium
-
Silberg, D. G. et al. CDX1 protein expression in normal, metaplastic, and neoplastic human alimentary tract epithelium. Gastroenterology 113, 478-486 (1997).
-
(1997)
Gastroenterology
, vol.113
, pp. 478-486
-
-
Silberg, D.G.1
-
49
-
-
0036559186
-
Gli and hedgehog in cancer: Tumours, embryos and stem cells
-
Ruiz I Altaba, A., Sanchez, P. & Dahmane, N. Gli and hedgehog in cancer: tumours, embryos and stem cells. Nature Rev. Cancer 2, 361-372 (2002).
-
(2002)
Nature Rev. Cancer
, vol.2
, pp. 361-372
-
-
Ruiz, I.1
Altaba, A.2
Sanchez, P.3
Dahmane, N.4
-
50
-
-
0033916281
-
Hedgehog signals regulate multiple aspects of gastrointestinal development
-
Ramalho-Santos, M., Melton, D. A. & McMahon, A. P. Hedgehog signals regulate multiple aspects of gastrointestinal development. Development 127, 2763-2772 (2000).
-
(2000)
Development
, vol.127
, pp. 2763-2772
-
-
Ramalho-Santos, M.1
Melton, D.A.2
McMahon, A.P.3
-
51
-
-
0036839405
-
Sonic hedgehog expression correlates with fundic gland differentiation in the adult gastrointestinal tract
-
van den Brink, G. R. et al. Sonic hedgehog expression correlates with fundic gland differentiation in the adult gastrointestinal tract. Gut 51, 628-633 (2002).
-
(2002)
Gut
, vol.51
, pp. 628-633
-
-
Van den Brink, G.R.1
-
52
-
-
0037097981
-
Neurogenin 3 is essential for the proper specification of gastric enteroendocrine cells and the maintenance of gastric epithelial cell identity
-
Lee, C. S., Perreault, N., Brestelli, J. E. & Kaestner, K. H. Neurogenin 3 is essential for the proper specification of gastric enteroendocrine cells and the maintenance of gastric epithelial cell identity. Genes Dev. 16, 1488-1497 (2002).
-
(2002)
Genes Dev.
, vol.16
, pp. 1488-1497
-
-
Lee, C.S.1
Perreault, N.2
Brestelli, J.E.3
Kaestner, K.H.4
-
53
-
-
0035083916
-
Augmented intestinal trefoil factor (TFF3) and loss of pS2 (TFF1) expression precedes metaplastic differentiation of gastric epithelium
-
Taupin, D. et al. Augmented intestinal trefoil factor (TFF3) and loss of pS2 (TFF1) expression precedes metaplastic differentiation of gastric epithelium. Lab. Invest. 81, 397-408 (2001).
-
(2001)
Lab. Invest.
, vol.81
, pp. 397-408
-
-
Taupin, D.1
-
54
-
-
0030032310
-
An intestine-specific homeobox gene regulates proliferation and differentiation
-
Suh, E. & Traber, P. G. An intestine-specific homeobox gene regulates proliferation and differentiation. Mol. Cell. Biol. 16, 619-625 (1996).
-
(1996)
Mol. Cell. Biol.
, vol.16
, pp. 619-625
-
-
Suh, E.1
Traber, P.G.2
-
55
-
-
0032577692
-
Expression of the Cdx1 and Cdx2 homeotic genes leads to reduced malignancy in colon cancer-derived cells
-
Mallo, G. V. et al. Expression of the Cdx1 and Cdx2 homeotic genes leads to reduced malignancy in colon cancer-derived cells. J. Biol. Chem. 273, 14030-14036 (1998).
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 14030-14036
-
-
Mallo, G.V.1
-
56
-
-
0029156944
-
Cdx-2 homeodomain protein expression in human and rat colorectal adenoma and carcinoma
-
Ee, H. C., Erler, T., Bhathal, P. S., Young, G. P. & James, R. J. Cdx-2 homeodomain protein expression in human and rat colorectal adenoma and carcinoma. Am. J. Pathol. 147, 586-592 (1995).
-
(1995)
Am. J. Pathol.
, vol.147
, pp. 586-592
-
-
Ee, H.C.1
Erler, T.2
Bhathal, P.S.3
Young, G.P.4
James, R.J.5
-
57
-
-
17344392128
-
Molecular cloning, sequencing and expression of the mRNA encoding human Cdx1 and Cdx2 homeobox. Down-regulation of Cdx 1 and Cdx2 mRNA expression during colorectal carcinogenesis
-
Mallo, G. V. et al. Molecular cloning, sequencing and expression of the mRNA encoding human Cdx1 and Cdx2 homeobox. Down-regulation of Cdx1 and Cdx2 mRNA expression during colorectal carcinogenesis. Int. J. Cancer 74, 35-44 (1997).
-
(1997)
Int. J. Cancer
, vol.74
, pp. 35-44
-
-
Mallo, G.V.1
-
58
-
-
0032737566
-
Cdx 1 promotes differentiation in a rat intestinal epithelial cell line
-
Soubeyran, P. et al. Cdx1 promotes differentiation in a rat intestinal epithelial cell line. Gastroenterology 117, 1326-1338 (1999).
-
(1999)
Gastroenterology
, vol.117
, pp. 1326-1338
-
-
Soubeyran, P.1
-
59
-
-
0033531262
-
Downregulation of the colon tumour-suppressor homeobox gene Cdx- 2 by oncogenic ras
-
Lorentz, O. et al. Downregulation of the colon tumour-suppressor homeobox gene Cdx-2 by oncogenic ras. Oncogene 18, 87-92 (1999).
-
(1999)
Oncogene
, vol.18
, pp. 87-92
-
-
Lorentz, O.1
-
60
-
-
0033833108
-
Wnt/β-catenin signaling regulates the expression of the homeobox gene Cdx 1 in embryonic intestine
-
Lickert, H. et al. Wnt/β-catenin signaling regulates the expression of the homeobox gene Cdx1 in embryonic intestine. Development 127, 3805-3813 (2000).
-
(2000)
Development
, vol.127
, pp. 3805-3813
-
-
Lickert, H.1
-
61
-
-
0034635456
-
The caudal-related homeodomain protein Cdx1 inhibits proliferation of intestinal epithelial cells by down-regulation of D-type cyclins
-
Lynch, J. et al. The caudal-related homeodomain protein Cdx1 inhibits proliferation of intestinal epithelial cells by down-regulation of D-type cyclins. J. Biol. Chem. 275, 4499-4506 (2000).
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 4499-4506
-
-
Lynch, J.1
-
62
-
-
0034076957
-
Helicobacter pylori infection and carcinogenesis of the stomach
-
Kuniyasu, H., Yasui, W., Yokozaki, H. & Tahara, E. Helicobacter pylori infection and carcinogenesis of the stomach. Langenbecks Arch. Surg. 385, 69-74 (2000).
-
(2000)
Langenbecks Arch. Surg.
, vol.385
, pp. 69-74
-
-
Kuniyasu, H.1
Yasui, W.2
Yokozaki, H.3
Tahara, E.4
-
63
-
-
0036966399
-
Inverse relationship between APC gene mutation in gastric adenomas and development of adenocarcinoma
-
Lee, J. H. et al. Inverse relationship between APC gene mutation in gastric adenomas and development of adenocarcinoma Am. J. Pathol. 161, 611-618 (2002).
-
(2002)
Am. J. Pathol.
, vol.161
, pp. 611-618
-
-
Lee, J.H.1
-
64
-
-
0030592517
-
Lessons from hereditary colorectal cancer
-
Kinzler K. W. & Vogelstein, B. Lessons from hereditary colorectal cancer. Cell 87, 159-170 (1996).
-
(1996)
Cell
, vol.87
, pp. 159-170
-
-
Kinzler, K.W.1
Vogelstein, B.2
-
65
-
-
0026948827
-
Somatic mutation of the APC gene in gastric cancer: Frequent mutations in very well differentiated adenocarcinoma and signet-ring cell carcinoma
-
Nakatsuru, S. et al. Somatic mutation of the APC gene in gastric cancer: frequent mutations in very well differentiated adenocarcinoma and signet-ring cell carcinoma. Hum. Mol. Genet. 1, 559-563 (1992).
-
(1992)
Hum. Mol. Genet.
, vol.1
, pp. 559-563
-
-
Nakatsuru, S.1
-
66
-
-
0028222940
-
Mutations of the APC gene occur during early stages of gastric adenoma development
-
Tamura, G. et al. Mutations of the APC gene occur during early stages of gastric adenoma development. Cancer Res. 54, 1149-1151 (1994).
-
(1994)
Cancer Res.
, vol.54
, pp. 1149-1151
-
-
Tamura, G.1
-
68
-
-
0001436407
-
Frequent somatic mutations of the β-catenin gene in intestinal-type gastric cancer
-
Park, W. S. et al. Frequent somatic mutations of the β-catenin gene in intestinal-type gastric cancer. Cancer Res. 59, 4257-4260 (1999).
-
(1999)
Cancer Res.
, vol.59
, pp. 4257-4260
-
-
Park, W.S.1
-
69
-
-
0034530165
-
Targeted mutations of transforming growth factor-β genes reveal important roles in mouse development and adult homeostasis
-
Dunker, N. & Krieglstein, K. Targeted mutations of transforming growth factor-β genes reveal important roles in mouse development and adult homeostasis. Eur. J. Biochem. 267, 6982-6988 (2000).
-
(2000)
Eur. J. Biochem.
, vol.267
, pp. 6982-6988
-
-
Dunker, N.1
Krieglstein, K.2
-
70
-
-
0030069171
-
Gastric lesions in transforming growth factor β- 1 heterozygous mice
-
Boivin, G. P., Molina, J. R., Ormsby I., Stemmermann, G. & Doetschman, T. Gastric lesions in transforming growth factor β-1 heterozygous mice. Lab. Invest. 74, 513-518 (1996).
-
(1996)
Lab. Invest.
, vol.74
, pp. 513-518
-
-
Boivin, G.P.1
Molina, J.R.2
Ormsby, I.3
Stemmermann, G.4
Doetschman, T.5
-
71
-
-
0028556486
-
Genetic changes in the transforming growth factor β (TGF-β) type II receptor gene in human gastric cancer cells: Correlation with sensitivity to growth inhibition by TGF-β
-
Park, K. et al. Genetic changes in the transforming growth factor β (TGF-β) type II receptor gene in human gastric cancer cells: correlation with sensitivity to growth inhibition by TGF-β. Proc. Natl Acad. Sci. USA 91, 8772-8776 (1994).
-
(1994)
Proc. Natl. Acad. Sci. USA
, vol.91
, pp. 8772-8776
-
-
Park, K.1
-
72
-
-
0032054728
-
Clinicopathological significance of altered loci of replication error and microsatellite instability-associated mutations in gastric cancer
-
Wu, M. S. et al. Clinicopathological significance of altered loci of replication error and microsatellite instability-associated mutations in gastric cancer. Cancer Res. 58, 1494-1497 (1998).
-
(1998)
Cancer Res.
, vol.58
, pp. 1494-1497
-
-
Wu, M.S.1
-
73
-
-
0032848687
-
Distinct methylation pattern and microsatellite instability in sporadic gastric cancer
-
Suzuki, H. et al. Distinct methylation pattern and microsatellite instability in sporadic gastric cancer. Int. J. Cancer 83, 309-313 (1999).
-
(1999)
Int. J. Cancer
, vol.83
, pp. 309-313
-
-
Suzuki, H.1
-
74
-
-
0033053670
-
Gastric carcinomas with microsatellite instability: Clinical features and mutations to the TGF-β type II receptor, IGFII receptor, and BAX genes
-
Iacopetta, B. J., Soong, R., House, A. K. & Hamelin, R. Gastric carcinomas with microsatellite instability: clinical features and mutations to the TGF-β type II receptor, IGFII receptor, and BAX genes. J. Pathol. 187, 428-432 (1999).
-
(1999)
J. Pathol.
, vol.187
, pp. 428-432
-
-
Iacopetta, B.J.1
Soong, R.2
House, A.K.3
Hamelin, R.4
-
75
-
-
0033802550
-
Microsatellite instability, prognosis and metastasis in gastric cancers from a low-risk population
-
Schneider, B. G. et al. Microsatellite instability, prognosis and metastasis in gastric cancers from a low-risk population. Int. J. Cancer 89, 444-452 (2000).
-
(2000)
Int. J. Cancer
, vol.89
, pp. 444-452
-
-
Schneider, B.G.1
-
76
-
-
0029066689
-
Inactivation of the type II TGF-β receptor in colon cancer cells with microsatellite instability
-
Markowitz, S. et al. Inactivation of the type II TGF-β receptor in colon cancer cells with microsatellite instability. Science 268, 1336-1338 (1995).
-
(1995)
Science
, vol.268
, pp. 1336-1338
-
-
Markowitz, S.1
-
77
-
-
0028785603
-
Microsatellite instability and mutations of the transforming growth factor β type II receptor gene in colorectal cancer
-
Parsons, R. et al. Microsatellite instability and mutations of the transforming growth factor β type II receptor gene in colorectal cancer. Cancer Res. 55, 5548-5550 (1995).
-
(1995)
Cancer Res.
, vol.55
, pp. 5548-5550
-
-
Parsons, R.1
-
78
-
-
18344389720
-
Causal relationship between the loss of RUNX 3 expression and gastric cancer
-
Li, Q. L. et al. Causal relationship between the loss of RUNX3 expression and gastric cancer. Cell 109, 113-124 (2002).
-
(2002)
Cell
, vol.109
, pp. 113-124
-
-
Li, Q.L.1
-
79
-
-
0025914631
-
Occurrence of p 53 gene abnormalities in gastric carcinoma tumors and cell lines
-
Kim, J. H. et al. Occurrence of p53 gene abnormalities in gastric carcinoma tumors and cell lines. J. Natl Cancer Inst. 83, 938-943 (1991).
-
(1991)
J. Natl. Cancer Inst.
, vol.83
, pp. 938-943
-
-
Kim, J.H.1
-
80
-
-
0025880420
-
Detection of frequent p53 gene mutations in primary gastric cancer by cell sorting and polymerase chain reaction single-strand conformation polymorphism analysis
-
Tamura, G. et al. Detection of frequent p53 gene mutations in primary gastric cancer by cell sorting and polymerase chain reaction single-strand conformation polymorphism analysis. Cancer Res. 51, 3056-3058 (1991).
-
(1991)
Cancer Res.
, vol.51
, pp. 3056-3058
-
-
Tamura, G.1
-
81
-
-
0023110098
-
The relationship between columnar epithelial dysplasia and invasive adenocarcinoma arising in Barrett's esophagus
-
Hamilton, S. R. & Smith, R. R. The relationship between columnar epithelial dysplasia and invasive adenocarcinoma arising in Barrett's esophagus. Am. J. Clin. Pathol. 87, 301-312 (1987).
-
(1987)
Am. J. Clin. Pathol.
, vol.87
, pp. 301-312
-
-
Hamilton, S.R.1
Smith, R.R.2
-
82
-
-
0038744602
-
Chronic acid exposure leads to activation of the Cdx2 intestinal homeobox gene in a long-term culture of mouse esophageal keratinocytes
-
Marchetti, M., Caliot, E. & Pringault, E. Chronic acid exposure leads to activation of the Cdx2 intestinal homeobox gene in a long-term culture of mouse esophageal keratinocytes. J. Cell Sci. 116, 1429-1436 (2003). Shows that chronic acid exposure leads to activation of Cdx2 expression in mouse oesophageal keratinocytes.
-
(2003)
J. Cell Sci.
, vol.116
, pp. 1429-1436
-
-
Marchetti, M.1
Caliot, E.2
Pringault, E.3
-
83
-
-
0021710405
-
Significance of intestinal metaplasia for the evolution of cancer in the biliary tract
-
Kozuka, S., Kurashina, M., Tsubone, M., Hachisuka, K. & Yasui, A. Significance of intestinal metaplasia for the evolution of cancer in the biliary tract. Cancer 54, 2277-2285 (1984).
-
(1984)
Cancer
, vol.54
, pp. 2277-2285
-
-
Kozuka, S.1
Kurashina, M.2
Tsubone, M.3
Hachisuka, K.4
Yasui, A.5
-
84
-
-
0027692070
-
Cholangiocarcinoma: Epidemiology, mechanisms of carcinogenesis and prevention
-
Parkin, D. M., Ohshima, H., Srivatanakul, P. & Vatanasapt, V. Cholangiocarcinoma: epidemiology, mechanisms of carcinogenesis and prevention. Cancer Epidemiol. Biomarkers Prev. 2, 537-544 (1993).
-
(1993)
Cancer Epidemiol. Biomarkers Prev.
, vol.2
, pp. 537-544
-
-
Parkin, D.M.1
Ohshima, H.2
Srivatanakul, P.3
Vatanasapt, V.4
-
85
-
-
0022586610
-
Intestinal-type adenocarcinoma of the gallbladder. A clinicopathologic study of seven cases
-
Albores-Saavedra, J., Nadji, M. & Henson, D. E. Intestinal-type adenocarcinoma of the gallbladder. A clinicopathologic study of seven cases. Am. J. Surg. Pathol. 10, 19-25 (1986).
-
(1986)
Am. J. Surg. Pathol.
, vol.10
, pp. 19-25
-
-
Albores-Saavedra, J.1
Nadji, M.2
Henson, D.E.3
-
86
-
-
0031899969
-
Hepatic Helicobacter species identified in bile and gallbladder tissue from Chileans with chronic cholecystitis
-
Fox, J. G. et al. Hepatic Helicobacter species identified in bile and gallbladder tissue from Chileans with chronic cholecystitis. Gastroenterology 114, 755-763 (1998).
-
(1998)
Gastroenterology
, vol.114
, pp. 755-763
-
-
Fox, J.G.1
-
87
-
-
0037288305
-
Aberrant expression of CDX2 in Barrett's epithelium and inflammatory esophageal mucosa
-
Eda, A. et al. Aberrant expression of CDX2 in Barrett's epithelium and inflammatory esophageal mucosa. J. Gastroenterol. 38, 14-22 (2003).
-
(2003)
J. Gastroenterol.
, vol.38
, pp. 14-22
-
-
Eda, A.1
-
88
-
-
0036789215
-
PTEN and TNF-α regulation of the intestinal-specific Cdx-2 homeobox gene through a PI3K, PKB/Akt, and NF-κB-dependent pathway
-
Kim, S. et al. PTEN and TNF-α regulation of the intestinal-specific Cdx-2 homeobox gene through a PI3K, PKB/Akt, and NF-κB-dependent pathway. Gastroenterology 23, 1163-1178 (2002). Shows that CDX2 is a target of PTEN/ phosphatidylinositol 3-kinase signalling and tumour necrosis factor-α.
-
(2002)
Gastroenterology
, vol.23
, pp. 1163-1178
-
-
Kim, S.1
-
89
-
-
0037042220
-
Stimulation of Cdx1 by oncogenic β-catenin/-Tcf4 in colon cancer cells; opposite effect of the CDX 2 homeoprotein
-
Domon-Dell, C. & Freund, J. N. Stimulation of Cdx1 by oncogenic β-catenin/-Tcf4 in colon cancer cells; opposite effect of the CDX2 homeoprotein. FEBS Lett. 518, 83-87 (2002).
-
(2002)
FEBS Lett.
, vol.518
, pp. 83-87
-
-
Domon-Dell, C.1
Freund, J.N.2
-
90
-
-
0034614094
-
Chemoprevention of gastric dysplasia: Randomized trial of antioxidant supplements and anti-Helicobacter pylori therapy
-
Correa, P. Chemoprevention of gastric dysplasia: randomized trial of antioxidant supplements and anti-Helicobacter pylori therapy J. Natl. Cancer Inst. 92, 1881-1888 (2000).
-
(2000)
J. Natl. Cancer Inst.
, vol.92
, pp. 1881-1888
-
-
Correa, P.1
-
91
-
-
0036089466
-
Aberrant expression of CDX2 in the gastric mucosa with and without intestinal metaplasia: Effect of eradication of Helicobacter pylori
-
Satoh, K. et al. Aberrant expression of CDX2 in the gastric mucosa with and without intestinal metaplasia: effect of eradication of Helicobacter pylori. Helicobacter 7, 192-198 (2002).
-
(2002)
Helicobacter
, vol.7
, pp. 192-198
-
-
Satoh, K.1
-
92
-
-
0035870282
-
INK4a and histology-specific methylation of CpG islands by exposure to tobacco smoke in non-small cell lung cancer
-
INK4a and histology-specific methylation of CpG islands by exposure to tobacco smoke in non-small cell lung cancer. Cancer Res. 61, 3419-3424 (2001).
-
(2001)
Cancer Res.
, vol.61
, pp. 3419-3424
-
-
Kim, D.H.1
-
93
-
-
0023752982
-
Use of all-trans retinoic acid in the treatment of acute promyelocytic leukemia
-
Huang, M. E. et al. Use of all-trans retinoic acid in the treatment of acute promyelocytic leukemia. Blood 72, 567-572 (1988).
-
(1988)
Blood
, vol.72
, pp. 567-572
-
-
Huang, M.E.1
-
94
-
-
0036274359
-
The fundamental role of epigenetic events in cancer
-
Jones, P. A. & Baylin, S. B. The fundamental role of epigenetic events in cancer. Nature Rev. Genet. 3, 415-428 (2002).
-
(2002)
Nature Rev. Genet.
, vol.3
, pp. 415-428
-
-
Jones, P.A.1
Baylin, S.B.2
-
95
-
-
0028208313
-
E-cadherin gene mutations in human gastric carcinoma cell lines
-
Oda, T. et al. E-cadherin gene mutations in human gastric carcinoma cell lines. Proc. Natl Acad. Sci. USA 91, 1858-1862 (1994).
-
(1994)
Proc. Natl. Acad. Sci. USA
, vol.91
, pp. 1858-1862
-
-
Oda, T.1
-
96
-
-
0029114538
-
Silencing of the E-cadherin invasion-suppressor gene by CpG methylation in human carcinomas
-
Yoshiura, K. et al. Silencing of the E-cadherin invasion-suppressor gene by CpG methylation in human carcinomas. Proc. Natl Acad. Sci. USA 92, 7416-7419 (1995).
-
(1995)
Proc. Natl. Acad. Sci. USA
, vol.92
, pp. 7416-7419
-
-
Yoshiura, K.1
-
97
-
-
0032568370
-
E-cadherin germline mutations in familial gastric cancer
-
Guilford, P. et al. E-cadherin germline mutations in familial gastric cancer. Nature 392, 402-405 (1998). First presentation of germline mutations in E-cadherin in hereditary diffuse gastric carcinoma.
-
(1998)
Nature
, vol.392
, pp. 402-405
-
-
Guilford, P.1
-
98
-
-
0036595629
-
Epithelial-mesenchymal transitions in tumour progression
-
Thiery, J. P. et al. Epithelial-mesenchymal transitions in tumour progression. Nature Rev. Cancer 2, 442-454 (2002).
-
(2002)
Nature Rev. Cancer
, vol.2
, pp. 442-454
-
-
Thiery, J.P.1
|