-
1
-
-
0027158031
-
Clues to the pathogenesis of familial colorectal cancer
-
Aaltonen, L.A., Peltomaki, P., Leach, F.S., Sistonen, P., Pylkkanen, L., Mecklin, J.P., Jarvinen, H., Powell, S.M., Jen, J., Hamilton, S.R., et al. (1993). Clues to the pathogenesis of familial colorectal cancer. Science 260, 812-816.
-
(1993)
Science
, vol.260
, pp. 812-816
-
-
Aaltonen, L.A.1
Peltomaki, P.2
Leach, F.S.3
Sistonen, P.4
Pylkkanen, L.5
Mecklin, J.P.6
Jarvinen, H.7
Powell, S.M.8
Jen, J.9
Hamilton, S.R.10
-
2
-
-
0025163524
-
Too many rodent carcinogens: Mitogenesis increases mutagenesis
-
Ames, B.N., and Gold, L.S. (1990). Too many rodent carcinogens: mitogenesis increases mutagenesis. Science 249, 970-971.
-
(1990)
Science
, vol.249
, pp. 970-971
-
-
Ames, B.N.1
Gold, L.S.2
-
3
-
-
0025634118
-
p53 gene mutations occur in combination with 17p allelic deletions as late events in colorectal tumorigenesis
-
Baker, S.J., Preisinger, A.C., Jessup, J.M., Paraskeva, C., Markowitz, S., Willson, J.K., Hamilton, S., and Vogelstein, B. (1990). p53 gene mutations occur in combination with 17p allelic deletions as late events in colorectal tumorigenesis. Cancer Res. 50, 7717-7722.
-
(1990)
Cancer Res.
, vol.50
, pp. 7717-7722
-
-
Baker, S.J.1
Preisinger, A.C.2
Jessup, J.M.3
Paraskeva, C.4
Markowitz, S.5
Willson, J.K.6
Hamilton, S.7
Vogelstein, B.8
-
4
-
-
0029781509
-
Functional interaction of beta-catenin with the transcription factor LEF-1
-
Behrens, J., von Kries, J.P., Kuhl, M., Bruhn, L., Wedlich, D., Grosschedl, R., and Birchmeier, W. (1996). Functional interaction of beta-catenin with the transcription factor LEF-1. Nature 382, 638-642.
-
(1996)
Nature
, vol.382
, pp. 638-642
-
-
Behrens, J.1
Von Kries, J.P.2
Kuhl, M.3
Bruhn, L.4
Wedlich, D.5
Grosschedl, R.6
Birchmeier, W.7
-
5
-
-
0029247944
-
Cell death in health and disease: The biology and regulation of apoptosis
-
Bellamy, C.O., Malcomson, R.D., Harrison, D.J., and Wyllie, A.H. (1995). Cell death in health and disease: the biology and regulation of apoptosis. Semin. Cancer Biol. 6, 3-16.
-
(1995)
Semin. Cancer Biol.
, vol.6
, pp. 3-16
-
-
Bellamy, C.O.1
Malcomson, R.D.2
Harrison, D.J.3
Wyllie, A.H.4
-
6
-
-
0029994517
-
A new member of the frizzled family from Drosophila functions as a Wingless receptor
-
Bhanot, P., Brink, M., Samos, C.H., Hsieh, J.-C., Wang, Y., Macke, J.P., Andrew, D., Nathans, J.,and Nusse, R. (1996). A new member of the frizzled family from Drosophila functions as a Wingless receptor. Nature 382, 225-230.
-
(1996)
Nature
, vol.382
, pp. 225-230
-
-
Bhanot, P.1
Brink, M.2
Samos, C.H.3
Hsieh, J.-C.4
Wang, Y.5
Macke, J.P.6
Andrew, D.7
Nathans, J.8
Nusse, R.9
-
7
-
-
0028224645
-
Mutator phenotypes in human colorectal carcinoma cell lines
-
Bhattacharyya, N.P., Skandalis, A., Ganesh, A., Groden, J., and Meuth, M. (1994). Mutator phenotypes in human colorectal carcinoma cell lines. Proc. Natl. Acad. Sci USA 91, 6319-6323.
-
(1994)
Proc. Natl. Acad. Sci USA
, vol.91
, pp. 6319-6323
-
-
Bhattacharyya, N.P.1
Skandalis, A.2
Ganesh, A.3
Groden, J.4
Meuth, M.5
-
8
-
-
0029895818
-
Genomic instability in colorectal carcinomas: Comparison of different evaluation methods and their biological significance
-
Bocker, M., Schlegel, J., Kullman, F., Stumm, G., Zirngibl, H., Epplen, J.T., and Ruschoff, J. (1996). Genomic instability in colorectal carcinomas: comparison of different evaluation methods and their biological significance. J. Pathology 179, 15-19.
-
(1996)
J. Pathology
, vol.179
, pp. 15-19
-
-
Bocker, M.1
Schlegel, J.2
Kullman, F.3
Stumm, G.4
Zirngibl, H.5
Epplen, J.T.6
Ruschoff, J.7
-
9
-
-
0023223410
-
Localization of the gene for familial adenomatous polyposis on chromosome 5
-
Bodmer, W., Bailey, C., Bodmer, J., Bussey, H., Ellis, A., Gorman, P., Lucibello, F., Murday, V., Rider, S., and Scambler, P. (1987). Localization of the gene for familial adenomatous polyposis on chromosome 5. Nature 328, 614-616.
-
(1987)
Nature
, vol.328
, pp. 614-616
-
-
Bodmer, W.1
Bailey, C.2
Bodmer, J.3
Bussey, H.4
Ellis, A.5
Gorman, P.6
Lucibello, F.7
Murday, V.8
Rider, S.9
Scambler, P.10
-
10
-
-
9344257283
-
Cyclooxygenase-2 overexpression and tumor formation are blocked by sulindac in a murine model of familial adenomatous polyposis
-
Boolbol, S.K., Dannenberg, A.J., Chadurn, A., Martucci, C., Guo, X., Ramonetti, J.T., Abreu-Goris, M., Newmark, H.L., Lipkin, M.L., DeCosse, J.J., and Bertagnolli, M.M. (1996). Cyclooxygenase-2 overexpression and tumor formation are blocked by sulindac in a murine model of familial adenomatous polyposis. Cancer Res. 56, 2556-2560.
-
(1996)
Cancer Res.
, vol.56
, pp. 2556-2560
-
-
Boolbol, S.K.1
Dannenberg, A.J.2
Chadurn, A.3
Martucci, C.4
Guo, X.5
Ramonetti, J.T.6
Abreu-Goris, M.7
Newmark, H.L.8
Lipkin, M.L.9
DeCosse, J.J.10
Bertagnolli, M.M.11
-
11
-
-
0029267352
-
Immune surveillance in colorectal carcinoma
-
Branch, P., Bicknell, D.C., Rowan, A., Bodmer, W.F., and Karran, P. (1995). Immune surveillance in colorectal carcinoma. Nat. Genet. 9, 231-232.
-
(1995)
Nat. Genet.
, vol.9
, pp. 231-232
-
-
Branch, P.1
Bicknell, D.C.2
Rowan, A.3
Bodmer, W.F.4
Karran, P.5
-
12
-
-
0023753017
-
Common inheritance of susceptibility to colonic adenomatous polyps and associated colorectal cancers
-
Cannon-Albright, L.A., Skolnick, M.H., Bishop, D.T., Lee, R.G., and Burt, R.W. (1988). Common inheritance of susceptibility to colonic adenomatous polyps and associated colorectal cancers. N. Engl. J. Med. 319, 533-537.
-
(1988)
N. Engl. J. Med.
, vol.319
, pp. 533-537
-
-
Cannon-Albright, L.A.1
Skolnick, M.H.2
Bishop, D.T.3
Lee, R.G.4
Burt, R.W.5
-
13
-
-
0025168534
-
Cell proliferation in carcinogenesis
-
Cohen, S.M., and Ellwein, L.B. (1990). Cell proliferation in carcinogenesis. Science 249, 1007-1011.
-
(1990)
Science
, vol.249
, pp. 1007-1011
-
-
Cohen, S.M.1
Ellwein, L.B.2
-
14
-
-
0028859670
-
Polymerase delta variants in RER colorectal tumours
-
da Costa, L.T., Liu, B., El-Deiry, W., Hamilton, S.R., Kinzler, K.W., Vogelstein, B., Markowitz, S., Willson, J.K., de la Chapelle, A., Downey, K.M., and So, A.G. (1995). Polymerase delta variants in RER colorectal tumours. Nat. Genet. 9, 10-11.
-
(1995)
Nat. Genet.
, vol.9
, pp. 10-11
-
-
Da Costa, L.T.1
Liu, B.2
El-Deiry, W.3
Hamilton, S.R.4
Kinzler, K.W.V.B.5
Markowitz, S.6
Willson, J.K.7
De La Chapelle, A.8
Downey, K.M.9
So, A.G.10
-
15
-
-
0028915012
-
Instability of microsatellites in human gliomas
-
Dams, E., Van de Kelft, E.J., Martin, J.J., Verlooy, J., and Willems, P.J. (1995). Instability of microsatellites in human gliomas. Cancer Res. 55, 1547-1549.
-
(1995)
Cancer Res.
, vol.55
, pp. 1547-1549
-
-
Dams, E.1
Van De Kelft, E.J.2
Martin, J.J.3
Verlooy, J.4
Willems, P.J.5
-
16
-
-
0028883366
-
Severe Gardner syndrome in families with mutations restricted to a specific region of the APC gene
-
Davies, D., Armstrong, J., Thakker, N., Horner, K., Guy, S., Clancy, T., Sloan, P., Blair, V., Dodd, C., and Warnes, T., et al. (1995). Severe Gardner syndrome in families with mutations restricted to a specific region of the APC gene. Am. J. Hum. Genet. 57, 1151-1158.
-
(1995)
Am. J. Hum. Genet.
, vol.57
, pp. 1151-1158
-
-
Davies, D.1
Armstrong, J.2
Thakker, N.3
Horner, K.4
Guy, S.5
Clancy, T.6
Sloan, P.7
Blair, V.8
Dodd, C.9
Warnes, T.10
-
17
-
-
0027363063
-
Genetic identification of Mom-1, a major modifier locus affecting Min-induced intestinal neoplasia in the mouse
-
Dietrich, W.F., Lander, E.S., Smith, J.S., Moser, A.R., Gould, K.A., Luongo, C., Borenstein, N., and Dove, W. (1993). Genetic identification of Mom-1, a major modifier locus affecting Min-induced intestinal neoplasia in the mouse. Cell 75, 631-639.
-
(1993)
Cell
, vol.75
, pp. 631-639
-
-
Dietrich, W.F.1
Lander, E.S.2
Smith, J.S.3
Moser, A.R.4
Gould, K.A.5
Luongo, C.6
Borenstein, N.7
Dove, W.8
-
18
-
-
0028887597
-
Increased mutation rate at the hprt locus accompanies microsatellite instability in colon cancer
-
Eshleman, J.R., Lang, E.Z., Bowerfind, G.K., Parsons, R., Vogelstein, B., Willson, J.K., Veigl, M.L., Sedwick, W.D., and Markowitz, S.D. (1995). Increased mutation rate at the hprt locus accompanies microsatellite instability in colon cancer. Oncogene 10, 33-37.
-
(1995)
Oncogene
, vol.10
, pp. 33-37
-
-
Eshleman, J.R.1
Lang, E.Z.2
Bowerfind, G.K.3
Parsons, R.4
Vogelstein, B.5
Willson, J.K.6
Veigl, M.L.7
Sedwick, W.D.8
Markowitz, S.D.9
-
19
-
-
0027742295
-
The human mutator gene homolog MSH2 and its association with hereditary nonpolyposis colon cancer
-
Fishel, R., Lescoe, M.K., Rao, M.R., Copeland, N.G., Jenkins, N.A., Garber, J., Kane, M., and Kolodner, R. (1993). The human mutator gene homolog MSH2 and its association with hereditary nonpolyposis colon cancer. Cell 75, 1027-1038.
-
(1993)
Cell
, vol.75
, pp. 1027-1038
-
-
Fishel, R.1
Lescoe, M.K.2
Rao, M.R.3
Copeland, N.G.4
Jenkins, N.A.5
Garber, J.6
Kane, M.7
Kolodner, R.8
-
20
-
-
0026324439
-
Follow-up study of twenty-four families with Li-Fraumeni syndrome
-
Garber, J.E., Goldstein, A.M., Kantor, A.F., Dreyfus, M.G., Fraumeni, J.F., Jr., and Li, F.P. (1991). Follow-up study of twenty-four families with Li-Fraumeni syndrome. Cancer Res. 51, 6094-6607.
-
(1991)
Cancer Res.
, vol.51
, pp. 6094-6607
-
-
Garber, J.E.1
Goldstein, A.M.2
Kantor, A.F.3
Dreyfus, M.G.4
Fraumeni J.F., Jr.5
Li, F.P.6
-
21
-
-
0002545071
-
Gastrointestinal polyposis sydromes and hereditary nonpolyposis colorectal cancer
-
A.K. Rustgi, ed. (Philadelphia: Lippincott-Raven)
-
Giardiello, F.M. (1995). Gastrointestinal polyposis sydromes and hereditary nonpolyposis colorectal cancer. In Gastrointestinal Cancers: Biology, Diagnosis, and Therapy, A.K. Rustgi, ed. (Philadelphia: Lippincott-Raven), pp. 367-377.
-
(1995)
Gastrointestinal Cancers: Biology, Diagnosis, and Therapy
, pp. 367-377
-
-
Giardiello, F.M.1
-
22
-
-
0027197062
-
Treatment of colonic and rectal adenomas with sulindac in familial adenomatous polyposis
-
Giardiello, F.M., Hamilton, S.R., Krush, A.J., Piantadosi, S., Hylind, L.M., Celano, P., Booker, S.V., Robinson, C.R., and Offerhaus, G.J. (1993). Treatment of colonic and rectal adenomas with sulindac in familial adenomatous polyposis. N. Engl. J. Med. 328, 1313-1316.
-
(1993)
N. Engl. J. Med.
, vol.328
, pp. 1313-1316
-
-
Giardiello, F.M.1
Hamilton, S.R.2
Krush, A.J.3
Piantadosi, S.4
Hylind, L.M.5
Celano, P.6
Booker, S.V.7
Robinson, C.R.8
Offerhaus, G.J.9
-
23
-
-
0028576901
-
Dietary factors and risk of colon cancer
-
Giovannucci, E., and Willett, W.C. (1994). Dietary factors and risk of colon cancer. Ann. Med. 26, 443-452.
-
(1994)
Ann. Med.
, vol.26
, pp. 443-452
-
-
Giovannucci, E.1
Willett, W.C.2
-
24
-
-
0025938038
-
Identification and characterization of the familial adenomatous polyposis coli gene
-
Groden, J., Thliveris, A., Samowitz, W., Carlson, M., Gelbert, L., Albertsen, H., Joslyn, G., Stevens, J., Spirio, L., Robertson, M., et al. (1991). Identification and characterization of the familial adenomatous polyposis coli gene. Cell 66, 589-600.
-
(1991)
Cell
, vol.66
, pp. 589-600
-
-
Groden, J.1
Thliveris, A.2
Samowitz, W.3
Carlson, M.4
Gelbert, L.5
Albertsen, H.6
Joslyn, G.7
Stevens, J.8
Spirio, L.9
Robertson, M.10
-
25
-
-
0028982101
-
Signal transduction of beta-catenin
-
Gumbiner, B.M. (1995). Signal transduction of beta-catenin. Curr. Opin. Cell Biol. 7, 634-640.
-
(1995)
Curr. Opin. Cell Biol.
, vol.7
, pp. 634-640
-
-
Gumbiner, B.M.1
-
26
-
-
0030593038
-
Dpc4, a candidate tumor suppressor gene at human chromosome 18q21.1
-
Hahn, S.A., Schutte, M., Hoque, A.T.M.S., Moskaluk, C.A., Dacosta, L.T., Rozenblum, E., Weinstein, C.L., Fischer, A., Yeo, C.J., Hruban, R.H., and Kern, S.E. (1996). Dpc4, a candidate tumor suppressor gene at human chromosome 18q21.1. Science 271, 350-353.
-
(1996)
Science
, vol.271
, pp. 350-353
-
-
Hahn, S.A.1
Schutte, M.2
Hoque, A.T.M.S.3
Moskaluk, C.A.4
Dacosta, L.T.5
Rozenblum, E.6
Weinstein, C.L.7
Fischer, A.8
Yeo, C.J.9
Hruban, R.H.10
Kern, S.E.11
-
27
-
-
0028970197
-
The molecular basis of Turcot's syndrome
-
Hamilton, S.R., Liu, B., Parsons, R.E., Papadopoulos, N., Jen, J., Powell, S.M., Krush, A.J., Berk, T., Cohen, Z., Tetu, B., et al. (1995). The molecular basis of Turcot's syndrome. N Engl J Med 332, 839-847.
-
(1995)
N Engl J Med
, vol.332
, pp. 839-847
-
-
Hamilton, S.R.1
Liu, B.2
Parsons, R.E.3
Papadopoulos, N.4
Jen, J.5
Powell, S.M.6
Krush, A.J.7
Berk, T.8
Cohen, Z.9
Tetu, B.10
-
28
-
-
0027489384
-
Clinical implications of the p53 tumor-suppressor gene
-
Harris, C.C., and Hollstein, M. (1993). Clinical implications of the p53 tumor-suppressor gene. N. Engl. J. Med. 329, 1318-1327.
-
(1993)
N. Engl. J. Med.
, vol.329
, pp. 1318-1327
-
-
Harris, C.C.1
Hollstein, M.2
-
29
-
-
0022810104
-
Gardner syndrome in a man with an interstitial deletion of 5q
-
Herrera, L., Kakati, S., Gibas, L., Pietrzak, E., and Sandberg, A. (1986). Gardner syndrome in a man with an interstitial deletion of 5q. Am. J. Med. Genet. 25, 473-476.
-
(1986)
Am. J. Med. Genet.
, vol.25
, pp. 473-476
-
-
Herrera, L.1
Kakati, S.2
Gibas, L.3
Pietrzak, E.4
Sandberg, A.5
-
30
-
-
0026699483
-
Dominant genes for colorectal cancer are not rare
-
Houlston, R.S., Collins, A., Slack, J., and Morton, N.E. (1992). Dominant genes for colorectal cancer are not rare. Ann. Hum. Genet. 56, 99-103.
-
(1992)
Ann. Hum. Genet.
, vol.56
, pp. 99-103
-
-
Houlston, R.S.1
Collins, A.2
Slack, J.3
Morton, N.E.4
-
31
-
-
0010945939
-
APC mutations in colorectal tumors with mismatch repair deficiency
-
Huang, J., Papadopoulos, N., McKinley, A.J., Farrington, S.M., Curtis, L.J., Wyllie, A.H., Zheng, S., Willson, J.K.V., Markowitz, S.D., Morin, P., et al. (1996). APC mutations in colorectal tumors with mismatch repair deficiency. Proc. Natl. Acad. Sci. USA 93, 9049-9054.
-
(1996)
Proc. Natl. Acad. Sci. USA
, vol.93
, pp. 9049-9054
-
-
Huang, J.1
Papadopoulos, N.2
McKinley, A.J.3
Farrington, S.M.4
Curtis, L.J.5
Wyllie, A.H.6
Zheng, S.7
Willson, J.K.V.8
Markowitz, S.D.9
Morin, P.10
-
32
-
-
0026920079
-
Inactivation of both APC alleles in an early stage of colon adenomas in a patient with familial adenomatous polyposis (FAP)
-
Ichii, S., Horii, A., Nakatsuru, S., Furuyama, J., Utsunomiya, J., and Nakamura, Y. (1992). Inactivation of both APC alleles in an early stage of colon adenomas in a patient with familial adenomatous polyposis (FAP). Hum. Mol. Genet. 1, 387-390.
-
(1992)
Hum. Mol. Genet.
, vol.1
, pp. 387-390
-
-
Ichii, S.1
Horii, A.2
Nakatsuru, S.3
Furuyama, J.4
Utsunomiya, J.5
Nakamura, Y.6
-
33
-
-
0027285475
-
Ubiquitous somatic mutations in simple repeated sequences reveal a new mechanism for colonic carcinogenesis
-
Ionov, Y., Peinado, M.A., Malkhosyan, S., Shibata, D., and Perucho, M. (1993). Ubiquitous somatic mutations in simple repeated sequences reveal a new mechanism for colonic carcinogenesis. Nature 363, 558-561.
-
(1993)
Nature
, vol.363
, pp. 558-561
-
-
Ionov, Y.1
Peinado, M.A.2
Malkhosyan, S.3
Shibata, D.4
Perucho, M.5
-
34
-
-
0027973077
-
Molecular determinants of dysplasia in colorectal lesions
-
Jen, J., Powell, S.M., Papadopoulos, N., Smith, K.J., Hamilton, S.R., Vogelstein, B., and Kinzler, K.W. (1994). Molecular determinants of dysplasia in colorectal lesions. Cancer Res. 54, 5523-5526.
-
(1994)
Cancer Res.
, vol.54
, pp. 5523-5526
-
-
Jen, J.1
Powell, S.M.2
Papadopoulos, N.3
Smith, K.J.4
Hamilton, S.R.5
Vogelstein, B.6
Kinzler, K.W.7
-
35
-
-
0027361020
-
Dimer formation by an N-terminal coiled coil in the APC protein
-
Joslyn, G., Richardson, D.S., White, R., and Alber, T. (1993). Dimer formation by an N-terminal coiled coil in the APC protein. Proc. Natl. Acad. Sci. USA 90, 11109-11113.
-
(1993)
Proc. Natl. Acad. Sci. USA
, vol.90
, pp. 11109-11113
-
-
Joslyn, G.1
Richardson, D.S.2
White, R.3
Alber, T.4
-
36
-
-
0028878974
-
Specific 5′-GGGA-3′→5′-GGA-3′ mutation of the Apc gene in rat colon tumors induced by 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine
-
Kakiuchi, H., Watanabe, M., Ushijima, T., Toyota, M., Imai, K., Weisburger, J.H., Sugimura, T., and Nagao, M. (1995). Specific 5′-GGGA-3′→5′-GGA-3′ mutation of the Apc gene in rat colon tumors induced by 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine. Proc. Natl. Acad. Sci. USA 92, 910-914.
-
(1995)
Proc. Natl. Acad. Sci. USA
, vol.92
, pp. 910-914
-
-
Kakiuchi, H.1
Watanabe, M.2
Ushijima, T.3
Toyota, M.4
Imai, K.5
Weisburger, J.H.6
Sugimura, T.7
Nagao, M.8
-
37
-
-
0027185632
-
From cadherins to catenins: Cytoplasmic protein interactions and regulation of cell adhesion
-
Kemler, R. (1993). From cadherins to catenins: cytoplasmic protein interactions and regulation of cell adhesion. Trends Genet. 9, 317-321.
-
(1993)
Trends Genet.
, vol.9
, pp. 317-321
-
-
Kemler, R.1
-
38
-
-
0027504088
-
Antioncogenes and human cancer
-
Knudson, A.G. (1993). Antioncogenes and human cancer. Proc. Natl. Acad. Sci. USA 90, 10914-10921.
-
(1993)
Proc. Natl. Acad. Sci. USA
, vol.90
, pp. 10914-10921
-
-
Knudson, A.G.1
-
39
-
-
0027936057
-
Human chromosome 3 corrects mismatch repair deficiency and microsatellite instability and reduces N-methyl-N′-nitro-N-nitrosoguanidine tolerance in colon tumor cells with homozygous hMLH1 mutation
-
Koi, M., Umar, A., Chauhan, D.P., Cherian, S.P., Carethers, J.M., Kunkel, T.A., and Boland, C.R. (1994). Human chromosome 3 corrects mismatch repair deficiency and microsatellite instability and reduces N-methyl-N′-nitro-N-nitrosoguanidine tolerance in colon tumor cells with homozygous hMLH1 mutation. Cancer Res. 54, 4308-4312.
-
(1994)
Cancer Res.
, vol.54
, pp. 4308-4312
-
-
Koi, M.1
Umar, A.2
Chauhan, D.P.3
Cherian, S.P.4
Carethers, J.M.5
Kunkel, T.A.6
Boland, C.R.7
-
40
-
-
0027145633
-
Mutations of a mutS homolog in hereditary nonpolyposis colorectal cancer
-
Leach, F.S., Nicolaides, N.C., Papadopoulos, N., Liu, B., Jen, J., Parsons, R., Peltomaki, P., Sistonen, P., Aaltonen, L.A., Nystrom-Lahti, M., et al. (1993). Mutations of a mutS homolog in hereditary nonpolyposis colorectal cancer. Cell 75, 1215-1225.
-
(1993)
Cell
, vol.75
, pp. 1215-1225
-
-
Leach, F.S.1
Nicolaides, N.C.2
Papadopoulos, N.3
Liu, B.4
Jen, J.5
Parsons, R.6
Peltomaki, P.7
Sistonen, P.8
Aaltonen, L.A.9
Nystrom-Lahti, M.10
-
41
-
-
0023572211
-
The gene for familial polyposis coli maps to the long arm of chromosome 5
-
Leppert, M., Dobbs, M., Scambler, P., O'Connell, P., Nakamura, Y., Stauffer, D., Woodward, S., Burt, R., Hughes, J., Gardner, E., and White, R. (1987). The gene for familial polyposis coli maps to the long arm of chromosome 5. Science 238, 1411-1443.
-
(1987)
Science
, vol.238
, pp. 1411-1443
-
-
Leppert, M.1
Dobbs, M.2
Scambler, P.3
O'Connell, P.4
Nakamura, Y.5
Stauffer, D.6
Woodward, S.7
Burt, R.8
Hughes, J.9
Gardner, E.10
White, R.11
-
42
-
-
0028051822
-
Inactivation of both APC alleles in human and mouse tumors
-
Levy, D.B., Smith, K.J., Beazer-Barclay, Y., Hamilton, S.R., Vogelstein, B., and Kinzler, K.W. (1994). Inactivation of both APC alleles in human and mouse tumors. Cancer Res. 54, 5953-5958.
-
(1994)
Cancer Res.
, vol.54
, pp. 5953-5958
-
-
Levy, D.B.1
Smith, K.J.2
Beazer-Barclay, Y.3
Hamilton, S.R.4
Vogelstein, B.5
Kinzler, K.W.6
-
43
-
-
0027485551
-
Genetic mapping of a second locus predisposing to hereditary non-polyposis colon cancer
-
Lindblom, A., Tannergard, P., Werelius, B., and Nordenskjold, M. (1993). Genetic mapping of a second locus predisposing to hereditary non-polyposis colon cancer. Nat. Genet. 5, 279-282.
-
(1993)
Nat. Genet.
, vol.5
, pp. 279-282
-
-
Lindblom, A.1
Tannergard, P.2
Werelius, B.3
Nordenskjold, M.4
-
44
-
-
0028859671
-
Mismatch repair gene defects in sporadic colorectal cancers with microsatellite instability
-
Liu, B., Nicolaides, N.C., Markowitz, S., Willson, J.K., Parsons, R.E., Jen, J., Papadopolous, N., Peltomaki, P., de la Chapelle, A., Hamilton, S.R., et al. (1995). Mismatch repair gene defects in sporadic colorectal cancers with microsatellite instability. Nat. Genet. 9, 48-55.
-
(1995)
Nat. Genet.
, vol.9
, pp. 48-55
-
-
Liu, B.1
Nicolaides, N.C.2
Markowitz, S.3
Willson, J.K.4
Parsons, R.E.5
Jen, J.6
Papadopolous, N.7
Peltomaki, P.8
De La Chapelle, A.9
Hamilton, S.R.10
-
45
-
-
2942569549
-
Analysis of mismatch repair genes in hereditary non-polyposis colorectal cancer patients
-
Liu, B., Parsons, R., Papadopoulos, N., Nicolaides, N.C., Lynch, H.T., Watson, P., Jass, J.R., Dunlop, M., Wyllie, A., Peltomaki, P., de la Chapelle, A., Hamilton, S.R., Vogelstein, B., and Kinzler, K.W. (1996). Analysis of mismatch repair genes in hereditary non-polyposis colorectal cancer patients. Nature Medicine 2, 169-174.
-
(1996)
Nature Medicine
, vol.2
, pp. 169-174
-
-
Liu, B.1
Parsons, R.2
Papadopoulos, N.3
Nicolaides, N.C.4
Lynch, H.T.5
Watson, P.6
Jass, J.R.7
Dunlop, M.8
Wyllie, A.9
Peltomaki, P.10
De La Chapelle, A.11
Hamilton, S.R.12
Vogelstein, B.13
Kinzler, K.W.14
-
46
-
-
0025773554
-
Mutator phenotype may be required for multistage carcinogenesis
-
Loeb, L.A. (1991). Mutator phenotype may be required for multistage carcinogenesis. Cancer Res. 51, 3075-3079.
-
(1991)
Cancer Res.
, vol.51
, pp. 3075-3079
-
-
Loeb, L.A.1
-
47
-
-
0027938331
-
Loss of Apc+ in intestinal adenomas from Min mice
-
Luongo, C., Moser, A.R., Gledhill, S., and Dove, W.F. (1994). Loss of Apc+ in intestinal adenomas from Min mice. Cancer Res. 54, 5947-5952.
-
(1994)
Cancer Res.
, vol.54
, pp. 5947-5952
-
-
Luongo, C.1
Moser, A.R.2
Gledhill, S.3
Dove, W.F.4
-
48
-
-
0029915034
-
Overview of natural history, pathology, molecular genetics and management of HNPCC (Lynch Syndrome)
-
Lynch, H.T., Smyrk, T., and Lynch, J.F. (1996). Overview of natural history, pathology, molecular genetics and management of HNPCC (Lynch Syndrome). Int. J. Cancer 69, 38-43.
-
(1996)
Int. J. Cancer
, vol.69
, pp. 38-43
-
-
Lynch, H.T.1
Smyrk, T.2
Lynch, J.F.3
-
49
-
-
0028998255
-
The secretory phospholipase A2 gene is a candidate for the Mom1 locus, a major modifier of ApcMin-induced intestinal neoplasia
-
MacPhee, M., Chepenik, K., Liddell, R., Nelson, K., Siracusa, L., and Buchberg, A. (1995). The secretory phospholipase A2 gene is a candidate for the Mom1 locus, a major modifier of ApcMin-induced intestinal neoplasia. Cell 81, 957-966.
-
(1995)
Cell
, vol.81
, pp. 957-966
-
-
Macphee, M.1
Chepenik, K.2
Liddell, R.3
Nelson, K.4
Siracusa, L.5
Buchberg, A.6
-
50
-
-
0029741089
-
Frameshift mutator mutations
-
Malkhosyan, S., Rampino, N., Yamamoto, H., and Perucho, M. (1996). Frameshift mutator mutations. Nature 382, 499-500.
-
(1996)
Nature
, vol.382
, pp. 499-500
-
-
Malkhosyan, S.1
Rampino, N.2
Yamamoto, H.3
Perucho, M.4
-
51
-
-
0029066689
-
Inactivation of the type II TGF-beta receptor in colon cancer cells with microsatellite instability
-
Markowitz, S., Wang, J., Myeroff, L., Parsons, R., Sun, L., Lutterbaugh, J., Fan, R.S., Zborowska, E., Kinzler, K.W., Vogelstein, B., et al. (1995). Inactivation of the type II TGF-beta receptor in colon cancer cells with microsatellite instability. Science 268, 1336-1338.
-
(1995)
Science
, vol.268
, pp. 1336-1338
-
-
Markowitz, S.1
Wang, J.2
Myeroff, L.3
Parsons, R.4
Sun, L.5
Lutterbaugh, J.6
Fan, R.S.7
Zborowska, E.8
Kinzler, K.W.9
Vogelstein, B.10
-
52
-
-
0029089259
-
Hereditary nonpolyposis colorectal cancer: The syndrome, the genes, and historical perspectives
-
Marra, G., and Boland, C.R. (1995). Hereditary nonpolyposis colorectal cancer: the syndrome, the genes, and historical perspectives. J. Natl. Cancer Inst. 87, 1114-1125.
-
(1995)
J. Natl. Cancer Inst.
, vol.87
, pp. 1114-1125
-
-
Marra, G.1
Boland, C.R.2
-
53
-
-
9344271549
-
Binding of APC to the human homolog of the drosophila discs large tumor suppressor protein
-
Matsumine, A., Ogai, A., Senda, T., Okumura, N., Satoh, K., Baeg, G.-H., Kawahara, T., Kobayashi, S., Okada, M., Toyoshima, K., and Akiyama, T. (1996). Binding of APC to the human homolog of the drosophila discs large tumor suppressor protein. Science 272, 1020-1023.
-
(1996)
Science
, vol.272
, pp. 1020-1023
-
-
Matsumine, A.1
Ogai, A.2
Senda, T.3
Okumura, N.4
Satoh, K.5
Baeg, G.-H.6
Kawahara, T.7
Kobayashi, S.8
Okada, M.9
Toyoshima, K.10
Akiyama, T.11
-
54
-
-
0029102368
-
Subcellular localization of the APC protein: Immunoelectron microscopic study of the association of the APC protein with catenin
-
Miyashiro, I., Senda, T., Matsumine, A., Baeg, G.H., Kuroda, T., Shimano, T., Miura, S., Noda, T., Kobayashi, S., Monden, M., Toyoshima, K., and Akiyama, T. (1995). Subcellular localization of the APC protein: immunoelectron microscopic study of the association of the APC protein with catenin. Oncogene 11, 89-96.
-
(1995)
Oncogene
, vol.11
, pp. 89-96
-
-
Miyashiro, I.1
Senda, T.2
Matsumine, A.3
Baeg, G.H.4
Kuroda, T.5
Shimano, T.6
Miura, S.7
Noda, T.8
Kobayashi, S.9
Monden, M.10
Toyoshima, K.11
Akiyama, T.12
-
55
-
-
0026894053
-
Somatic mutations of the APC gene in colorectal tumors: Mutation cluster region in the APC gene
-
Miyoshi, Y., Nagase, H., Ando, H., Horii, A., Ichii, S., Nakatsuru, S., Aoki, T., Miki, Y., Mori, T., and Nakamura, Y. (1992). Somatic mutations of the APC gene in colorectal tumors: mutation cluster region in the APC gene. Hum. Mol. Genet. 1, 229-233.
-
(1992)
Hum. Mol. Genet.
, vol.1
, pp. 229-233
-
-
Miyoshi, Y.1
Nagase, H.2
Ando, H.3
Horii, A.4
Ichii, S.5
Nakatsuru, S.6
Aoki, T.7
Miki, Y.8
Mori, T.9
Nakamura, Y.10
-
56
-
-
0029654337
-
Mismatch repair, genetic stability and tumour avoidance
-
Modrich, P. (1995). Mismatch repair, genetic stability and tumour avoidance. Phil. R. Soc. Lond. B. Biol. Sci. 347, 89-95.
-
(1995)
Phil. R. Soc. Lond. B. Biol. Sci.
, vol.347
, pp. 89-95
-
-
Modrich, P.1
-
57
-
-
0001003110
-
XTcf-3 transcription factor mediates beta-catenin-induced axis formation in Xenopus embryos
-
Molenaar, M., van de Wetering, M., Oosterwegel, M., Peterson-Maduro, J., Godsave, S., Korinek, V., Roose, J., Destree, O., and Clevers, H. (1996). XTcf-3 transcription factor mediates beta-catenin-induced axis formation in Xenopus embryos. Cell 86, 391-399.
-
(1996)
Cell
, vol.86
, pp. 391-399
-
-
Molenaar, M.1
Van De Wetering, M.2
Oosterwegel, M.3
Peterson-Maduro, J.4
Godsave, S.5
Korinek, V.6
Roose, J.7
Destree, O.8
Clevers, H.9
-
58
-
-
0029799144
-
Apoptosis and APC in colorectal tumorigenesis
-
Morin, P.J., Vogelstein, B., and Kinzler, K.W. (1996). Apoptosis and APC in colorectal tumorigenesis. Proc. Natl. Acad. Sci. USA 93, 7950-7954.
-
(1996)
Proc. Natl. Acad. Sci. USA
, vol.93
, pp. 7950-7954
-
-
Morin, P.J.1
Vogelstein, B.2
Kinzler, K.W.3
-
59
-
-
0027930066
-
The APC gene product associates with microtubules in vivo and promotes their assembly in vitro
-
Munemitsu, S., Souza, B., Muller, O., Albert, I., Rubinfeld, B., and Polakis, P. (1994). The APC gene product associates with microtubules in vivo and promotes their assembly in vitro. Cancer Res. 54, 3676-3681.
-
(1994)
Cancer Res.
, vol.54
, pp. 3676-3681
-
-
Munemitsu, S.1
Souza, B.2
Muller, O.3
Albert, I.4
Rubinfeld, B.5
Polakis, P.6
-
60
-
-
0028987249
-
Regulation of intracellular beta-catenin levels by the adenomatous polyposis coli (APC) tumor-suppressor protein
-
Munemitsu, S., Albert, I., Souza, B., Rubinfeld, B., and Polakis, P. (1995). Regulation of intracellular beta-catenin levels by the adenomatous polyposis coli (APC) tumor-suppressor protein. Proc. Natl. Acad. Sci. USA 92, 3046-3050.
-
(1995)
Proc. Natl. Acad. Sci. USA
, vol.92
, pp. 3046-3050
-
-
Munemitsu, S.1
Albert, I.2
Souza, B.3
Rubinfeld, B.4
Polakis, P.5
-
61
-
-
0027146559
-
Mutations of the APC (adenomatous polyposis coli) gene
-
Nagase, H., and Nakamura, Y. (1993). Mutations of the APC (adenomatous polyposis coli) gene. Hum. Mutat. 2, 425-434.
-
(1993)
Hum. Mutat.
, vol.2
, pp. 425-434
-
-
Nagase, H.1
Nakamura, Y.2
-
62
-
-
0025899162
-
Mutations of chromosome 5q21 genes in FAP and colorectal cancer patients
-
Nishisho, I., Nakamura, Y., Miyoshi, Y., Miki, Y., Ando, H., Horii, A., Koyama, K., Utsunomiya, J., Baba, S., and Hedge, P., et al. (1991). Mutations of chromosome 5q21 genes in FAP and colorectal cancer patients. Science 253, 665-669.
-
(1991)
Science
, vol.253
, pp. 665-669
-
-
Nishisho, I.1
Nakamura, Y.2
Miyoshi, Y.3
Miki, Y.4
Ando, H.5
Horii, A.6
Koyama, K.7
Utsunomiya, J.8
Baba, S.9
Hedge, P.10
-
63
-
-
0026772731
-
Wnt genes
-
Nusse, R., and Varmus, H.E. (1992). Wnt genes. Cell 69, 1073-1087.
-
(1992)
Cell
, vol.69
, pp. 1073-1087
-
-
Nusse, R.1
Varmus, H.E.2
-
64
-
-
0027769633
-
Restriction of ocular fundus lesions to a specific subgroup of APC mutations in adenomatous polyposis coli patients
-
Olschwang, S., Tiret, A., Laurent-Puig, P., Muleris, M., Parc, R., and Thomas, G. (1993). Restriction of ocular fundus lesions to a specific subgroup of APC mutations in adenomatous polyposis coli patients. Cell 75, 959-968.
-
(1993)
Cell
, vol.75
, pp. 959-968
-
-
Olschwang, S.1
Tiret, A.2
Laurent-Puig, P.3
Muleris, M.4
Parc, R.5
Thomas, G.6
-
65
-
-
0029008683
-
GTBP, a 160-kilodalton protein essential for mismatch-binding activity in human cells
-
Palombo, F., Gallinari, P., Iaccarino, I., Lettieri, T., Hughes, M., A., D.A., Truong, O., Hsuan, J.J., and Jiricny, J. (1995). GTBP, a 160-kilodalton protein essential for mismatch-binding activity in human cells. Science 268, 1912-1914.
-
(1995)
Science
, vol.268
, pp. 1912-1914
-
-
Palombo, F.1
Gallinari, P.2
Iaccarino, I.3
Lettieri, T.4
Hughes, M.5
A., D.A.6
Truong, O.7
Hsuan, J.J.8
Jiricny, J.9
-
66
-
-
0029659046
-
hMutSβ, a heterodimer of hMSH2 and hMSH3, binds to insertion/deletion loops in DNA
-
Palombo, F., Iaccarino, I., Nakajima, E., Ikejima, M., Shimada, T., and Jiriony, J. (1996). hMutSβ, a heterodimer of hMSH2 and hMSH3, binds to insertion/deletion loops in DNA. Curr. Biol. 6, 1181-1184.
-
(1996)
Curr. Biol.
, vol.6
, pp. 1181-1184
-
-
Palombo, F.1
Iaccarino, I.2
Nakajima, E.3
Ikejima, M.4
Shimada, T.5
Jiriony, J.6
-
67
-
-
0029069972
-
Mutations of GTBP in genetically unstable cells
-
Papadopoulos, N., Nicolaides, N.C., Liu, B., Parsons, R., Lengauer, C., Palombo, F., A, D.A., Markowitz, S., Willson, J.K., Kinzler, K.W., Jiricny, J.W., and Vogelstein, B. (1995). Mutations of GTBP in genetically unstable cells. Science 268, 1915-1917.
-
(1995)
Science
, vol.268
, pp. 1915-1917
-
-
Papadopoulos, N.1
Nicolaides, N.C.2
Liu, B.3
Parsons, R.4
Lengauer, C.5
Palombo, F.6
A., D.A.7
Markowitz, S.8
Willson, J.K.9
Kinzler, K.W.10
Jiricny, J.W.11
Vogelstein, B.12
-
68
-
-
0030043446
-
Cancer statistics, 1996
-
Parker, S., Tong, T., Bolden, S., and Wingo, P. (1996). Cancer statistics, 1996. CA Cancer J. Clin. 46, 5-27.
-
(1996)
CA Cancer J. Clin.
, vol.46
, pp. 5-27
-
-
Parker, S.1
Tong, T.2
Bolden, S.3
Wingo, P.4
-
69
-
-
0027137935
-
Hypermutability and mismatch repair deficiency in RER+ tumor cells
-
Parsons, R., Li, G.M., Longley, M.J., Fang, W.H., Papadopoulos, N., Jen, J., de la Chapelle, A., Kinzler, K.W., Vogelstein, B., and Modrich, P. (1993). Hypermutability and mismatch repair deficiency in RER+ tumor cells. Cell 75, 1227-1236.
-
(1993)
Cell
, vol.75
, pp. 1227-1236
-
-
Parsons, R.1
Li, G.M.2
Longley, M.J.3
Fang, W.H.4
Papadopoulos, N.5
Jen, J.6
De La Chapelle, A.7
Kinzler, K.W.8
Vogelstein, B.9
Modrich, P.10
-
70
-
-
0029061638
-
Mismatch repair deficiency in phenotypically normal human cells
-
Parsons, R., Li, G.M., Longley, M., Modrich, P., Liu, B., Berk, T., Hamilton, S.R., Kinzler, K.W., and Vogelstein, B. (1995). Mismatch repair deficiency in phenotypically normal human cells. Science 268, 738-740.
-
(1995)
Science
, vol.268
, pp. 738-740
-
-
Parsons, R.1
Li, G.M.2
Longley, M.3
Modrich, P.4
Liu, B.5
Berk, T.6
Hamilton, S.R.7
Kinzler, K.W.8
Vogelstein, B.9
-
71
-
-
0026439207
-
Isolation and characterization of allelic losses and gains in colorectal tumors by arbitrarily primed polymerase chain reaction
-
Peinado, M.A., Malkhosyan, S., Velazquez, A., and Perucho, M. (1992). Isolation and characterization of allelic losses and gains in colorectal tumors by arbitrarily primed polymerase chain reaction. Proc. Natl. Acad. Sci. USA 89, 10065-10069.
-
(1992)
Proc. Natl. Acad. Sci. USA
, vol.89
, pp. 10065-10069
-
-
Peinado, M.A.1
Malkhosyan, S.2
Velazquez, A.3
Perucho, M.4
-
72
-
-
0027263363
-
Genetic mapping of a locus predisposing to human colorectal cancer
-
Peltomaki, P., Aaltonen, L.A., Sistonen, P., Pylkkanen, L., Mecklin, J.P., Jarvinen, H., Green, J.S., Jass, J.R., Weber, J.L., Leach, F.S., Petersen, G.M., Hamilton, S.R., de la Chapelle, A., and Vogelstein, B. (1993). Genetic mapping of a locus predisposing to human colorectal cancer. Science 260, 810-812.
-
(1993)
Science
, vol.260
, pp. 810-812
-
-
Peltomaki, P.1
Aaltonen, L.A.2
Sistonen, P.3
Pylkkanen, L.4
Mecklin, J.P.5
Jarvinen, H.6
Green, J.S.7
Jass, J.R.8
Weber, J.L.9
Leach, F.S.10
Petersen, G.M.11
Hamilton, S.R.12
De La Chapelle, A.13
Vogelstein, B.14
-
73
-
-
0026630266
-
APC mutations occur early during colorectal tumorigenesis
-
Powell, S.M., Zilz, N., Beazer-Barclay, Y., Bryan, T.M., Hamilton, S.R., Thibodeau, S.N., Vogelstein, B., and Kinzler, K.W. (1992). APC mutations occur early during colorectal tumorigenesis. Nature 359, 235-237.
-
(1992)
Nature
, vol.359
, pp. 235-237
-
-
Powell, S.M.1
Zilz, N.2
Beazer-Barclay, Y.3
Bryan, T.M.4
Hamilton, S.R.5
Thibodeau, S.N.6
Vogelstein, B.7
Kinzler, K.W.8
-
74
-
-
0027763498
-
Molecular diagnosis of familial adenomatous polyposis
-
Powell, S.M., Petersen, G.M., Krush, A.J., Booker, S., Jen, J., Giardiello, F.M., Hamilton, S.R., Vogelstein, B., and Kinzler, K.W. (1993). Molecular diagnosis of familial adenomatous polyposis. N. Engl. J. Med. 329, 1982-1987.
-
(1993)
N. Engl. J. Med.
, vol.329
, pp. 1982-1987
-
-
Powell, S.M.1
Petersen, G.M.2
Krush, A.J.3
Booker, S.4
Jen, J.5
Giardiello, F.M.6
Hamilton, S.R.7
Vogelstein, B.8
Kinzler, K.W.9
-
75
-
-
0027138093
-
K-ras mutations in putative preneoplastic lesions in human colon
-
Pretlow, T.P., Brasitus, T.A., Fulton, N.C., Cheyer, C., and Kaplan, E.L. (1993). K-ras mutations in putative preneoplastic lesions in human colon. J. Natl. Cancer Inst. 85, 2004-2007.
-
(1993)
J. Natl. Cancer Inst.
, vol.85
, pp. 2004-2007
-
-
Pretlow, T.P.1
Brasitus, T.A.2
Fulton, N.C.3
Cheyer, C.4
Kaplan, E.L.5
-
76
-
-
8944262831
-
MSH2 deficiency contributes to accelerated APC-mediated intestinal tumorigenesis
-
Reitmair, A.H., Cai, J.-C., Bjerknes, M., Redston, M., Cheng, H., Pind, M.T.L, Hay, K., Mitri, A., Bapat, B.V., Mak, T.W., and Gallinger, S. (1996). MSH2 deficiency contributes to accelerated APC-mediated intestinal tumorigenesis. Cancer Res. 56, 2922-2926.
-
(1996)
Cancer Res.
, vol.56
, pp. 2922-2926
-
-
Reitmair, A.H.1
Cai, J.-C.2
Bjerknes, M.3
Redston, M.4
Cheng, H.5
Pind, M.T.L.6
Hay, K.7
Mitri, A.8
Bapat, B.V.9
Mak, T.W.10
Gallinger, S.11
-
77
-
-
15844387270
-
Mad-related genes in the human
-
Riggins, G.J., Thiagalingam, S., Rozenblum, E., Weinstein, C.L., Kern, S.E., Hamilton, S.R., Willson, J.K.V., Markowitz, S.D., Kinzler, K.W., and Vogelstein, B. (1996). Mad-related genes in the human. Nature Genetics 13, 347-349.
-
(1996)
Nature Genetics
, vol.13
, pp. 347-349
-
-
Riggins, G.J.1
Thiagalingam, S.2
Rozenblum, E.3
Weinstein, C.L.4
Kern, S.E.5
Hamilton, S.R.6
Willson, J.K.V.7
Markowitz, S.D.8
Kinzler, K.W.9
Vogelstein, B.10
-
78
-
-
0027738023
-
Association of the APC gene product with beta-catenin
-
Rubinfeld, B., Souza, B., Albert, I., Muller, O., Chamberlain, S.H., Masiarz, F.R., Munemitsu, S., and Polakis, P. (1993). Association of the APC gene product with beta-catenin. Science 262, 1731-1734.
-
(1993)
Science
, vol.262
, pp. 1731-1734
-
-
Rubinfeld, B.1
Souza, B.2
Albert, I.3
Muller, O.4
Chamberlain, S.H.5
Masiarz, F.R.6
Munemitsu, S.7
Polakis, P.8
-
79
-
-
0029664368
-
Binding of GSK3-beta to the APC-beta-catenin complex and regulation of complex assembly
-
Rubinfeld, B., Albert, I., Porfiri, E., Fiol, C., Munemitsu, S., and Polakis, P. (1996). Binding of GSK3-beta to the APC-beta-catenin complex and regulation of complex assembly. Science 272, 1023-1025.
-
(1996)
Science
, vol.272
, pp. 1023-1025
-
-
Rubinfeld, B.1
Albert, I.2
Porfiri, E.3
Fiol, C.4
Munemitsu, S.5
Polakis, P.6
-
80
-
-
0027196626
-
Genetic heterogeneity of the c-K-ras locus in colorectal adenomas but not in adenocarcinomas
-
Shibata, D., Schaeffer, J., Li, Z.H., Capella, G., and Perucho, M. (1993). Genetic heterogeneity of the c-K-ras locus in colorectal adenomas but not in adenocarcinomas. J. Natl. Cancer Inst. 85, 1058-1063.
-
(1993)
J. Natl. Cancer Inst.
, vol.85
, pp. 1058-1063
-
-
Shibata, D.1
Schaeffer, J.2
Li, Z.H.3
Capella, G.4
Perucho, M.5
-
81
-
-
0028362325
-
Genomic instability in repeated sequences is an early somatic event in colorectal tumorigenesis that persists after transformation
-
Shibata, D., Peinado, M.A., Ionov, Y., Malkhosyan, S., and Perucho, M. (1994). Genomic instability in repeated sequences is an early somatic event in colorectal tumorigenesis that persists after transformation. Nat. Genet. 6, 273-281.
-
(1994)
Nat. Genet.
, vol.6
, pp. 273-281
-
-
Shibata, D.1
Peinado, M.A.2
Ionov, Y.3
Malkhosyan, S.4
Perucho, M.5
-
82
-
-
0030037367
-
Natural history of aberrant crypt foci
-
Shpitz, B.H.K., Medline, A., Bruce, W.R., Bull, S.B., Gallinger, S., and Stern, H. (1996). Natural history of aberrant crypt foci. Dis. Colon Rectum 39, 763-767.
-
(1996)
Dis. Colon Rectum
, vol.39
, pp. 763-767
-
-
Shpitz, B.H.K.1
Medline, A.2
Bruce, W.R.3
Bull, S.B.4
Gallinger, S.5
Stern, H.6
-
83
-
-
0027394231
-
The APC gene product in normal and tumor cells
-
Smith, K.J., Johnson, K.A., Bryan, T.M., Hill, D.E., Markowitz, S., Willson, J.K., Paraskeva, C., Petersen, G.M., Hamilton, S.R., Vogelstein, B., and Kinzler, K.W. (1993). The APC gene product in normal and tumor cells. Proc. Natl. Acad. Sci. USA 90, 2846-2850.
-
(1993)
Proc. Natl. Acad. Sci. USA
, vol.90
, pp. 2846-2850
-
-
Smith, K.J.1
Johnson, K.A.2
Bryan, T.M.3
Hill, D.E.4
Markowitz, S.5
Willson, J.K.6
Paraskeva, C.7
Petersen, G.M.8
Hamilton, S.R.9
Vogelstein, B.10
Kinzler, K.W.11
-
84
-
-
0027991585
-
Wild-type but not mutant APC associates with the microtubule cytoskeleton
-
Smith, K.J., Levy, D.B., Maupin, P., Pollard, T.D., Vogelstein, B., and Kinzler, K.W. (1994). Wild-type but not mutant APC associates with the microtubule cytoskeleton. Cancer Res 54, 3672-3675.
-
(1994)
Cancer Res
, vol.54
, pp. 3672-3675
-
-
Smith, K.J.1
Levy, D.B.2
Maupin, P.3
Pollard, T.D.4
Vogelstein, B.5
Kinzler, K.W.6
-
85
-
-
0027724691
-
Alleles of the APC gene: An attenuated form of familial polyposis
-
Spirio, L., Olschwang, S., Groden, J., Robertson, M., Samowitz, W., Joslyn, G., Gelbert, L., Thliveris, A., Carlson, M., Otterud, B., et al. (1993). Alleles of the APC gene: an attenuated form of familial polyposis. Cell 75, 951-957.
-
(1993)
Cell
, vol.75
, pp. 951-957
-
-
Spirio, L.1
Olschwang, S.2
Groden, J.3
Robertson, M.4
Samowitz, W.5
Joslyn, G.6
Gelbert, L.7
Thliveris, A.8
Carlson, M.9
Otterud, B.10
-
86
-
-
0027306173
-
Destabilization of tracts of simple repetitive DNA in yeast by mutations affecting DNA mismatch repair
-
Strand, M., Prolla, T.A., Liskay, R.M., and Petes, T.D. (1993). Destabilization of tracts of simple repetitive DNA in yeast by mutations affecting DNA mismatch repair. Nature 365, 274-276.
-
(1993)
Nature
, vol.365
, pp. 274-276
-
-
Strand, M.1
Prolla, T.A.2
Liskay, R.M.3
Petes, T.D.4
-
87
-
-
0026562404
-
Multiple intestinal neoplasia caused by a mutation in the murine homolog of the APC gene
-
Su, L.K., Kinzler, K.W., Vogelstein, B., Preisinger, A.C., Moser, A.R., Luongo, C., Gould, K.A., and Dove, W.F. (1992). Multiple intestinal neoplasia caused by a mutation in the murine homolog of the APC gene. Science 256, 668-670.
-
(1992)
Science
, vol.256
, pp. 668-670
-
-
Su, L.K.1
Kinzler, K.W.2
Vogelstein, B.3
Preisinger, A.C.4
Moser, A.R.5
Luongo, C.6
Gould, K.A.7
Dove, W.F.8
-
88
-
-
0027756014
-
Association of the APC tumor suppressor protein with catenins
-
Su, L.K., Vogelstein, B., and Kinzler, K.W. (1993). Association of the APC tumor suppressor protein with catenins. Science 262, 1734-1737.
-
(1993)
Science
, vol.262
, pp. 1734-1737
-
-
Su, L.K.1
Vogelstein, B.2
Kinzler, K.W.3
-
89
-
-
0029066006
-
APC binds to the novel protein EB1
-
Su, LK., Burrell, M., Hill, D.E., Gyuris, J., Brent, R., Wiltshire, R., Trent, J., Vogelstein, B., and Kinzler, K.W. (1995). APC binds to the novel protein EB1. Cancer Res. 55, 2972-2977.
-
(1995)
Cancer Res.
, vol.55
, pp. 2972-2977
-
-
Su, L.K.1
Burrell, M.2
Hill, D.E.3
Gyuris, J.4
Brent, R.5
Wiltshire, R.6
Trent, J.7
Vogelstein, B.8
Kinzler, K.W.9
-
90
-
-
0029125296
-
Inherited breast and ovarian cancer
-
Szabo, C.I., and King, M.C. (1995). Inherited breast and ovarian cancer. Hum. Mol. Genet. 4, 1811-1817.
-
(1995)
Hum. Mol. Genet.
, vol.4
, pp. 1811-1817
-
-
Szabo, C.I.1
King, M.C.2
-
91
-
-
0027314411
-
Microsatellite instability in cancer of the proximal colon
-
Thibodeau, S.N., Bren, G., and Schaid, D. (1993). Microsatellite instability in cancer of the proximal colon. Science 260, 816-819.
-
(1993)
Science
, vol.260
, pp. 816-819
-
-
Thibodeau, S.N.1
Bren, G.2
Schaid, D.3
-
92
-
-
0028301255
-
Defective mismatch repair in extracts of colorectal and endometrial cancer cell lines exhibiting microsatellite instability
-
Umar, A., Boyer, J.C., Thomas, D.C., Nguyen, D.C., Risinger, J.I., Boyd, J., Ionov, Y., Perucho, M., and Kunkel, T.A. (1994). Defective mismatch repair in extracts of colorectal and endometrial cancer cell lines exhibiting microsatellite instability. J. Biol. Chem. 269, 14367-14370.
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 14367-14370
-
-
Umar, A.1
Boyer, J.C.2
Thomas, D.C.3
Nguyen, D.C.4
Risinger, J.I.5
Boyd, J.6
Ionov, Y.7
Perucho, M.8
Kunkel, T.A.9
-
93
-
-
0028289053
-
Rapid detection of translation-terminating mutations at the adenomatous polyposis coli (APC) gene by direct protein truncation test
-
van der Luijt, R., Khan, P.M., Vasen, H., van Leeuwen, C., Tops, C., Roest, P., den Dunnen, J., and Fodde, R. (1994). Rapid detection of translation-terminating mutations at the adenomatous polyposis coli (APC) gene by direct protein truncation test. Genomics 20, 1-4.
-
(1994)
Genomics
, vol.20
, pp. 1-4
-
-
Van Der Luijt, R.1
Khan, P.M.2
Vasen, H.3
Van Leeuwen, C.4
Tops, C.5
Roest, P.6
Den Dunnen, J.7
Fodde, R.8
-
94
-
-
0023748414
-
Genetic alterations during colorectal-tumor development
-
Vogelstein, B., Fearon, E.R., Hamilton, S.R., Kern, S.E., Preisinger, A.C., Leppert, M., Nakamura, Y., White, R., Smits, A.M., and Bos, J.L. (1988). Genetic alterations during colorectal-tumor development. N. Engl. J. Med. 319, 525-532.
-
(1988)
N. Engl. J. Med.
, vol.319
, pp. 525-532
-
-
Vogelstein, B.1
Fearon, E.R.2
Hamilton, S.R.3
Kern, S.E.4
Preisinger, A.C.5
Leppert, M.6
Nakamura, Y.7
White, R.8
Smits, A.M.9
Bos, J.L.10
-
95
-
-
0028889967
-
Expression cloning of oncogenes by retroviral transfer of cDNA libraries
-
Whitehead, I., Kirk, H., and Kay, R. (1995). Expression cloning of oncogenes by retroviral transfer of cDNA libraries. Mol. Cell. Biol. 15, 704-710.
-
(1995)
Mol. Cell. Biol.
, vol.15
, pp. 704-710
-
-
Whitehead, I.1
Kirk, H.2
Kay, R.3
-
96
-
-
0027452417
-
Genomic instability occurs in colorectal carcinomas but not in adenomas
-
Young, J., Leggett, B., Gustafson, C., Ward, M., Searle, J., Thomas, L., Buttenshaw, R., and Chenevix-Trench, G. (1993). Genomic instability occurs in colorectal carcinomas but not in adenomas. Hum. Mutat. 2, 351-354.
-
(1993)
Hum. Mutat.
, vol.2
, pp. 351-354
-
-
Young, J.1
Leggett, B.2
Gustafson, C.3
Ward, M.4
Searle, J.5
Thomas, L.6
Buttenshaw, R.7
Chenevix-Trench, G.8
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