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Volumn 295, Issue 5564, 2002, Pages 2387-2392
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Matrix metalloproteinase inhibitors and cancer: Trials and tribulations
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Author keywords
[No Author keywords available]
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Indexed keywords
ENZYME INHIBITION;
ONCOLOGY;
SUBSTRATES;
MALIGNANT TISSUES;
TUMORS;
AE 941;
CARBOPLATIN;
CISPLATIN;
COLLAGENASE 3;
CYTOTOXIC AGENT;
GELATINASE A;
GELATINASE B;
GEMCITABINE;
IMATINIB;
INTERSTITIAL COLLAGENASE;
MARIMASTAT;
MATRILYSIN;
MATRIX METALLOPROTEINASE;
MATRIX METALLOPROTEINASE 14;
MATRIX METALLOPROTEINASE INHIBITOR;
MITOXANTRONE;
PACLITAXEL;
PLACEBO;
PREDNISONE;
PRINOMASTAT;
PROTEIN TYROSINE KINASE INHIBITOR;
REBIMASTAT;
STROMELYSIN;
STROMELYSIN 2;
STROMELYSIN 3;
TANOMASTAT;
TISSUE INHIBITOR OF METALLOPROTEINASE 1;
TISSUE INHIBITOR OF METALLOPROTEINASE 2;
CANCER;
DRUG DEVELOPMENT;
ANTINEOPLASTIC ACTIVITY;
BONE PAIN;
CANCER COMBINATION CHEMOTHERAPY;
CANCER INHIBITION;
CANCER STAGING;
CLINICAL TRIAL;
CONTROLLED CLINICAL TRIAL;
CONTROLLED STUDY;
DRUG INDUCED DISEASE;
DRUG MECHANISM;
DRUG RESEARCH;
ENZYME INHIBITION;
HUMAN;
INFLAMMATION;
MALIGNANT NEOPLASTIC DISEASE;
MYALGIA;
PHASE 1 CLINICAL TRIAL;
PHASE 2 CLINICAL TRIAL;
PHASE 3 CLINICAL TRIAL;
PRIORITY JOURNAL;
REVIEW;
ANIMALS;
ANTINEOPLASTIC AGENTS;
CLINICAL TRIALS;
DISEASE PROGRESSION;
DRUG EVALUATION, PRECLINICAL;
EXTRACELLULAR MATRIX;
HUMANS;
MATRIX METALLOPROTEINASES;
NEOPLASM METASTASIS;
NEOPLASMS;
PROTEASE INHIBITORS;
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EID: 0037192458
PISSN: 00368075
EISSN: None
Source Type: Journal
DOI: 10.1126/science.1067100 Document Type: Review |
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Times cited : (2479)
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References (59)
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