Computational design gains momentum in enzyme catalysis engineering

FEBS Journal

Volumn 280, Issue 13, 2013, Pages 2948-2960

  Wijma, Hein J ^a   Janssen, Dick B ^a  

^a UNIVERSITY OF GRONINGEN   (Netherlands)

Author keywords

biocatalysis; computer aided enzyme design; computer aided protein design; enzymatic activity; in silico design; loop grafting; ranking; stability; substrate scope; substrate specificity

Indexed keywords

ALGORITHM; BINDING AFFINITY; BIOCATALYST; CATALYSIS; COMPUTATIONAL DESIGN; CONFERENCE PAPER; ENERGY; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME CONFORMATION; ENZYME ENGINEERING; ENZYME STRUCTURE; ENZYME SUBSTRATE; ENZYME SUBSTRATE COMPLEX; MATHEMATICAL COMPUTING; MICHAELIS CONSTANT; MOLECULAR DYNAMICS; POINT MUTATION; PRIORITY JOURNAL; PROTEIN ENGINEERING; SEARCH ALGORITHM; X RAY CRYSTALLOGRAPHY;

ANIMALS; BIOCATALYSIS; BIOMEDICAL RESEARCH; BIOTECHNOLOGY; COMPUTATIONAL BIOLOGY; HUMANS; MODELS, MOLECULAR; MOLECULAR DYNAMICS SIMULATION; PROTEIN ENGINEERING; RECOMBINANT PROTEINS;

EID: 84879219232     PISSN: 1742464X     EISSN: 17424658     Source Type: Journal    
DOI: 10.1111/febs.12324     Document Type: Conference Paper

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