Binding Pocket Optimization by Computational Protein Design

PLoS ONE

Volumn 7, Issue 12, 2012, Pages

  Malisi, Christoph ^a   Schumann, Marcel ^b,d   Toussaint, Nora C ^b,c   Kageyama, Jorge ^a   Kohlbacher, Oliver ^b   Höcker, Birte ^a  

^a MAX PLANCK INSTITUTE FOR DEVELOPMENTAL BIOLOGY   (Germany)

^b UNIVERSITY OF TÜBINGEN   (Germany)

^c THOMAS JEFFERSON UNIVERSITY   (United States)

^d MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALGORITHM; ARTICLE; BINDING AFFINITY; COMPUTATIONAL PROTEIN DESIGN; GENE MUTATION; GEOMETRY; HYDROGEN BOND; LIGAND BINDING; MATHEMATICAL MODEL; MOLECULAR MODEL; PREDICTION; PROCESS DEVELOPMENT; PROCESS OPTIMIZATION; PROTEIN BINDING; PROTEIN MODIFICATION; PROTEIN TARGETING; QUALITY CONTROL;

BENCHMARKING; BINDING SITES; COMPUTATIONAL BIOLOGY; DRUG DESIGN; LIGANDS; PROTEIN BINDING; PROTEINS; SOFTWARE;

EQUUS ASINUS;

EID: 84871644617     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0052505     Document Type: Article

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