Design of a switchable eliminase

Proceedings of the National Academy of Sciences of the United States of America

Volumn 108, Issue 17, 2011, Pages 6823-6827

  Korendovych, Ivan V ^a   Kulp, Daniel W ^a   Wu, Yibing ^a   Cheng, Hong ^b   Roder, Heinrich ^a,b   DeGrado, William F ^a,b  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b FOX CHASE CANCER CENTER   (United States)

Author keywords

Catalysis; pKa; Protein design

Indexed keywords

ALLEYCAT PROTEIN; ASPARTIC ACID; CALCIUM ION; CALMODULIN; CARBOXYLIC ACID; ELIMINASE; GLUTAMIC ACID; GLUTAMINE; LYASE; MUTANT PROTEIN; UNCLASSIFIED DRUG;

ALLOSTERISM; ARTICLE; CATALYST; ELIMINATION REACTION; ENZYME ACTIVE SITE; ENZYME ANALYSIS; ENZYME CONFORMATION; ENZYME MECHANISM; ENZYME STABILITY; ENZYME SUBSTRATE; MICHAELIS CONSTANT; PKA; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN FOLDING;

ALLOSTERIC REGULATION; AMINO ACID SUBSTITUTION; ANIMALS; CALMODULIN; CATALYSIS; CHICKENS; COMPUTER SIMULATION; MODELS, MOLECULAR; MUTATION, MISSENSE; PROTEIN FOLDING; PROTEIN STRUCTURE, TERTIARY;

EID: 79955570791     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1018191108     Document Type: Article

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