New algorithms and an in silico benchmark for computational enzyme design

Protein Science

Volumn 15, Issue 12, 2006, Pages 2785-2794

  Zanghellini, Alexandre ^a,b   Jiang, Lin ^a,b   Wollacott, Andrew M ^a   Cheng, Gong ^a,b   Meiler, Jens ^c   Althoff, Eric A ^a   Röthlisberger, Daniela ^a   Baker, David ^a,b  

^a UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF WASHINGTON   (United States)

^c VANDERBILT UNIVERSITY   (United States)

Author keywords

Active site recapitulation; Enzyme design; Geometric hashing; Protein design; Protein ligand interactions

Indexed keywords

SCAFFOLD PROTEIN;

ALGORITHM; ARTICLE; CATALYSIS; CHEMICAL REACTION; COMPUTER MODEL; CRYSTAL STRUCTURE; ENZYME ACTIVE SITE; ENZYME STRUCTURE; GEOMETRY; MATHEMATICAL COMPUTING; METHODOLOGY; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN CONFORMATION;

ALGORITHMS; ANIMALS; BACILLUS; BINDING SITES; CARBOXY-LYASES; CATTLE; COMPUTATIONAL BIOLOGY; CRYSTALLOGRAPHY; ENZYME ACTIVATION; ENZYMES; ESCHERICHIA COLI; FRUCTOSE-BISPHOSPHATE ALDOLASE; MODELS, MOLECULAR; PLANT VIRUSES; PROTEIN CONFORMATION; PROTEIN ENGINEERING; SACCHAROMYCES CEREVISIAE;

EID: 33751525692     PISSN: 09618368     EISSN: 1469896X     Source Type: Journal    
DOI: 10.1110/ps.062353106     Document Type: Article

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