Increasing sequence diversity with flexible backbone protein design: The complete redesign of a protein hydrophobic core

Structure

Volumn 20, Issue 6, 2012, Pages 1086-1096

  Murphy, Grant S ^a   Mills, Jeffrey L ^b,c   Miley, Michael J ^c,d   Machius, Mischa ^c,d   Szyperski, Thomas ^b,c   Kuhlman, Brian ^c,d  

^a University of North Carolina at Chapel Hill   (United States)

^b UNIVERSITY AT BUFFALO   (United States)

^c UNIVERSITY OF NORTH CAROLINA   (United States)

^d UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIAL PROTEIN; PROTEIN DRAA; PROTEIN DRNN; PROTEIN FBAA; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; ARTICLE; HYDROPHOBICITY; NONHUMAN; NUCLEAR MAGNETIC RESONANCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN STRUCTURE; TEMPERATURE MEASUREMENT;

ALGORITHMS; AMINO ACID SEQUENCE; BACTERIAL PROTEINS; CRYSTALLOGRAPHY, X-RAY; HYDROGEN BONDING; HYDROPHOBIC AND HYDROPHILIC INTERACTIONS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MONTE CARLO METHOD; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR; PROTEIN ENGINEERING; PROTEIN STABILITY; PROTEIN STRUCTURE, SECONDARY; THERMOTOGA MARITIMA; TRANSITION TEMPERATURE;

EID: 84861966405     PISSN: 09692126     EISSN: 18784186     Source Type: Journal    
DOI: 10.1016/j.str.2012.03.026     Document Type: Article

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