Construction of a catalytically active iron superoxide dismutase by rational protein design

Proceedings of the National Academy of Sciences of the United States of America

Volumn 94, Issue 11, 1997, Pages 5562-5567

  Pinto, Ann L ^a   Hellinga, Homme W ^b   Caradonna, John P ^a  

^a YALE UNIVERSITY   (United States)

^b DUKE UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

Dismutation; Metalloenzymes; Nonheme iron; Rational protein design; Superoxide ion

Indexed keywords

IRON; SUPEROXIDE DISMUTASE;

ARTICLE; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME SYNTHESIS; ESCHERICHIA COLI; GENE EXPRESSION; MOLECULAR CLONING; NONHUMAN; PRIORITY JOURNAL;

ALGORITHMS; APOENZYMES; BINDING SITES; COMPUTER SIMULATION; ESCHERICHIA COLI; IRON; MODELS, STRUCTURAL; MUTAGENESIS, SITE-DIRECTED; PROTEIN ENGINEERING; PROTEIN STRUCTURE, SECONDARY; RECOMBINANT FUSION PROTEINS; SUPEROXIDE DISMUTASE; THIOREDOXIN;

ESCHERICHIA COLI;

EID: 0030978103     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.94.11.5562     Document Type: Article

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