Computational design of an endo-1,4-β-xylanase ligand binding site

Protein Engineering, Design and Selection

Volumn 24, Issue 6, 2011, Pages 503-516

  Morin, Andrew ^a   Kaufmann, Kristian W ^a   Fortenberry, Carie ^a   Harp, Joel M ^b   Mizoue, Laura S ^b   Meiler, Jens ^a  

^a VANDERBILT UNIVERSITY   (United States)

^b VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

xylanase fold; computational protein design; protein dynamics; proteinligand interface; Rosetta

Indexed keywords

COMPUTATIONAL PROTEIN DESIGN; PROTEIN DYNAMICS; PROTEINLIGAND INTERFACE; ROSETTA; XYLANASES;

AMINO ACIDS; BINDING ENERGY; BIOCHEMICAL ENGINEERING; LIGANDS; PROTEINS;

SCAFFOLDS (BIOLOGY);

AGAR; AMINO ACID; DOCKING PROTEIN; ENDO 1,4 BETA XYLANASE; LIGAND;

ACCURACY; AMINO ACID SUBSTITUTION; ANISOTROPY; ARTICLE; BINDING AFFINITY; BINDING SITE; CATALYSIS; COMPUTER MODEL; CONFORMATION; CRYSTALLOGRAPHY; MATHEMATICAL ANALYSIS; NONHUMAN; NONOMURAEA FLEXUOSA; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN STRUCTURE; THERMOPHILE; VALIDATION STUDY; YEAST;

ACTINOMYCETALES; BINDING SITES; COMPUTATIONAL BIOLOGY; COMPUTER SIMULATION; CRYSTALLOGRAPHY; ENDO-1,4-BETA XYLANASES; MOLECULAR DYNAMICS SIMULATION; MONTE CARLO METHOD; PROTEIN ENGINEERING; PROTEIN STRUCTURE, TERTIARY; SOFTWARE; VANCOMYCIN;

THERMOPOLYSPORA FLEXUOSA;

EID: 79956080813     PISSN: 17410126     EISSN: 17410134     Source Type: Journal    
DOI: 10.1093/protein/gzr006     Document Type: Article

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