Backrub-Like Backbone Simulation Recapitulates Natural Protein Conformational Variability and Improves Mutant Side-Chain Prediction

Journal of Molecular Biology

Volumn 380, Issue 4, 2008, Pages 742-756

  Smith, Colin A ^a,b   Kortemme, Tanja ^a,b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

backrub motion; flexible backbone sampling; Monte Carlo; point mutation; triosephosphate isomerase loop 6

Indexed keywords

PROTEIN;

ARTICLE; CONFORMATIONAL TRANSITION; CRYSTAL STRUCTURE; MODEL; PRIORITY JOURNAL; PROTEIN CONFORMATION; SAMPLING; SIMULATION;

EID: 45649084560     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jmb.2008.05.023     Document Type: Article

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