A synthetic homing endonuclease-based gene drive system in the human malaria mosquito

Nature

Volumn 473, Issue 7346, 2011, Pages 212-215

  Windbichler, Nikolai ^a   Menichelli, Miriam ^a   Papathanos, Philippos Aris ^a   Thyme, Summer B ^b,c   Li, Hui ^c   Ulge, Umut Y ^c   Hovde, Blake T ^c   Baker, David ^b,c   Monnat, Raymond J ^c   Burt, Austin ^a   Crisanti, Andrea ^a,d  

^a IMPERIAL COLLEGE LONDON   (United Kingdom)

^b UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF WASHINGTON   (United States)

^d UNIVERSITY OF PERUGIA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

ENDONUCLEASE; HOMING ENDONUCLEASE; INSECT PROTEIN; PROTEIN I SCEI; UNCLASSIFIED DRUG;

CHROMOSOME; DISEASE CONTROL; DISEASE RESISTANCE; DISEASE TRANSMISSION; DISEASE VECTOR; ENZYME ACTIVITY; GENE EXPRESSION; GENETIC ANALYSIS; GENETIC ENGINEERING; GENETICALLY MODIFIED ORGANISM; MALARIA; MOLECULAR ANALYSIS; MOSQUITO; POPULATION STRUCTURE;

ANIMAL EXPERIMENT; ANOPHELES GAMBIAE; ARTICLE; CHROMOSOME; CONTROLLED STUDY; EMBRYO; ENZYME SYNTHESIS; FEMALE; GENE CONTROL; GENE CONVERSION; GENE EXPRESSION; GERM LINE; HUMAN; INSECT GENETICS; MALARIA; MALE; MOLECULAR DYNAMICS; MOSQUITO; NONHUMAN; NUCLEOTIDE SEQUENCE; PARASITE TRANSMISSION; PARASITE VECTOR; PRIORITY JOURNAL; PROGENY; PROTEIN TRANSPORT; RECEPTIVE FIELD; REGULATOR GENE; TRANSGENIC ANIMAL;

ANIMALS; ANIMALS, GENETICALLY MODIFIED; ANOPHELES GAMBIAE; DEOXYRIBONUCLEASES, TYPE II SITE-SPECIFIC; FEMALE; GENES, REPORTER; GENETIC ENGINEERING; GENOTYPE; INSECT VECTORS; MALE; MOLECULAR SEQUENCE DATA; MOSQUITO CONTROL; SACCHAROMYCES CEREVISIAE PROTEINS;

ANOPHELES GAMBIAE;

EID: 79955922770     PISSN: 00280836     EISSN: 14764687     Source Type: Journal    
DOI: 10.1038/nature09937     Document Type: Article

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