Toward accurate screening in computer-aided enzyme design

Biochemistry

Volumn 48, Issue 14, 2009, Pages 3046-3056

  Roca, Maite ^a,b   Vardi Kilshtain, Alexandra ^a   Warshel, Arieh ^a  

^a UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

^b UNIVERSITAT JAUME I   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVATION FREE ENERGIES; ACTIVE SITES; BINDING FREE ENERGIES; CATALYTIC POWER; CHORISMATE MUTASE; CURRENT GENERATIONS; DESIGN APPROACHES; ENZYME CATALYSIS; FAST SCREENINGS; GAS-PHASE; NATIVE ENZYMES; PREORGANIZATION; QUALITATIVE SCREENINGS; SIMULATION APPROACHES; SMALL CLUSTERS; TRANSITION STATE; VALENCE BONDS;

ACTIVATION ENERGY; BINDING ENERGY; BIOCHEMISTRY; CATALYSTS; DESIGN; FREE ENERGY; IONIZATION OF GASES;

ENZYMES;

CHORISMATE MUTASE; DNA POLYMERASE; PREPHENATE DEHYDROGENASE;

ACCURACY; ARTICLE; BACILLUS SUBTILIS; CATALYSIS; COMPUTER AIDED DESIGN; ELECTRICITY; ELECTRON TRANSPORT; ENERGY; ENZYME ANALYSIS; ENZYME BINDING; ENZYME CONFORMATION; ENZYME MECHANISM; ENZYME STRUCTURE; ESCHERICHIA COLI; IONIZATION; PRIORITY JOURNAL; PROTEIN INTERACTION; QUALITATIVE ANALYSIS; RELIABILITY; SCREENING; SIMULATION;

CATALYSIS; CATALYTIC DOMAIN; CHORISMATE MUTASE; COMPUTER SIMULATION; COMPUTER-AIDED DESIGN; ENZYMES; MODELS, MOLECULAR; PROTEIN ENGINEERING; STATIC ELECTRICITY; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 65249154106     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi802191b     Document Type: Article

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