The moderately efficient enzyme: Evolutionary and physicochemical trends shaping enzyme parameters

Biochemistry

Volumn 50, Issue 21, 2011, Pages 4402-4410

  Bar Even, Arren ^a   Noor, Elad ^a   Savir, Yonatan ^a   Liebermeister, Wolfram ^a   Davidi, Dan ^a   Tawfik, Dan S ^a   Milo, Ron ^a  

^a WEIZMANN INSTITUTE OF SCIENCE   (Israel)

Author keywords

[No Author keywords available]

Indexed keywords

BIOLOGICAL PROCESS; CATALYTIC EFFICIENCIES; DIFFUSION LIMITS; EVOLUTIONARY SELECTION; GLOBAL TRENDS; LOW MOLECULAR MASS; MAXIMAL RATES; NATURAL SUBSTRATES; PHYSICOCHEMICAL PROPERTY; SECONDARY METABOLISM; SELECTION PRESSURES;

CATALYSTS; KINETIC PARAMETERS; METABOLISM; PHYSIOLOGY; SUBSTRATES;

ENZYMES;

ARTICLE; DIFFUSION; ENZYME KINETICS; ENZYME MECHANISM; ENZYME METABOLISM; ENZYME SUBSTRATE; HUMAN; HYDROPHOBICITY; MOLECULAR WEIGHT; NATURAL SELECTION; NONHUMAN; PHYSICAL CHEMISTRY; PRIORITY JOURNAL; PROTEIN DATABASE;

BIOLOGICAL EVOLUTION; ENZYMES; KINETICS; PRESSURE;

EID: 79958097953     PISSN: 00062960     EISSN: 15204995     Source Type: Journal    
DOI: 10.1021/bi2002289     Document Type: Article

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