Endogenous metabolites as ligands for G protein-coupled receptors modulating risk factors for metabolic and cardiovascular disease

American Journal of Physiology - Heart and Circulatory Physiology

Volumn 304, Issue 4, 2013, Pages

  Tonack, Sarah ^a   Tang, Cong ^a   Offermanns, Stefan ^a,b  

^a MAX PLANCK INSTITUTE FOR HEART AND LUNG RESEARCH   (Germany)

^b GOETHE UNIVERSITY   (Germany)

Author keywords

Bile acid; Carbohydrates; Fatty acid; G protein coupled receptors; Ketone bodies; Lactate

Indexed keywords

2 OXOGLUTARIC ACID; 3 HYDROXYBUTYRIC ACID; ACYLGLYCEROL PALMITOYLTRANSFERASE; AMINO ACID DERIVATIVE; AROMATIC AMINO ACID; BILE ACID; CALCIUM SENSING RECEPTOR; CARBOHYDRATE; DISACCHARIDE; FRUCTOSE; G PROTEIN COUPLED RECEPTOR; G PROTEIN COUPLED RECEPTOR 119; G PROTEIN COUPLED RECEPTOR 120; G PROTEIN COUPLED RECEPTOR 93; G PROTEIN COUPLED RECEPTOR C6A; G PROTEIN COUPLED RECEPTOR84; GLUCOSE; KETONE BODY; LACTIC ACID; LACTOSE; LONG CHAIN FATTY ACID; MALTOSE; MEDIUM CHAIN FATTY ACID; MONOSACCHARIDE; PEPTONE; SHORT CHAIN FATTY ACID; SUCCINIC ACID; SUCROSE; TASTE TYPE 1 RECEPTOR 2; TASTE TYPE 1 RECEPTOR 3; UNCLASSIFIED DRUG;

ADIPOSE TISSUE; CARDIOVASCULAR DISEASE; CARDIOVASCULAR SYSTEM; DIABETES MELLITUS; DRUG TARGETING; DYSLIPIDEMIA; ENDOCRINE GLAND; FOOD INTAKE; GASTROINTESTINAL TRACT; HUMAN; IMMUNOCOMPETENT CELL; KIDNEY; METABOLIC DISORDER; METABOLISM; NONHUMAN; OBESITY; OXIDATION; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; REVIEW; RISK FACTOR; TASTE BUD;

AMINO ACIDS; ANIMALS; CARBOHYDRATE METABOLISM; CARDIOVASCULAR DISEASES; FEMALE; HUMANS; LIGANDS; LIPID METABOLISM; MALE; MICE; PEPTONES; RATS; RECEPTORS, G-PROTEIN-COUPLED; RISK FACTORS;

EID: 84874059987     PISSN: 03636135     EISSN: 15221539     Source Type: Journal    
DOI: 10.1152/ajpheart.00641.2012     Document Type: Review

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