Anatomical Profiling of G Protein-Coupled Receptor Expression

Cell

Volumn 135, Issue 3, 2008, Pages 561-571

  Regard, Jean B ^a   Sato, Isaac T ^a   Coughlin, Shaun R ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

MOLNEURO; RNA; SIGNALING

Indexed keywords

G PROTEIN COUPLED RECEPTOR; G PROTEIN COUPLED RECEPTOR 91; LIGAND; SUCCINIC ACID; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; CITRIC ACID CYCLE; CLUSTER ANALYSIS; CONTROLLED STUDY; ENERGY BALANCE; GENE EXPRESSION PROFILING; LIPOLYSIS; MOUSE; MULTIGENE FAMILY; NONHUMAN; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; REGULATORY MECHANISM; SIGNAL TRANSDUCTION; WHITE ADIPOSE TISSUE;

ANIMALS; GENE EXPRESSION; GENOME; LIPOLYSIS; MICE; RECEPTORS, G-PROTEIN-COUPLED; SUCCINIC ACID;

EID: 54549087794     PISSN: 00928674     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cell.2008.08.040     Document Type: Article

References (94)

1. Amizuka N., Lee H.S., Kwan M.Y., Arazani A., Warshawsky H., Hendy G.N., Ozawa H., White J.H., and Goltzman D. Cell-specific expression of the parathyroid hormone (PTH)/PTH-related peptide receptor gene in kidney from kidney-specific and ubiquitous promoters. Endocrinology 138 (1997) 469-481
2. Bates B., Zhang L., Nawoschik S., Kodangattil S., Tseng E., Kopsco D., Kramer A., Shan Q., Taylor N., Johnson J., et al. Characterization of Gpr101 expression and G-protein coupling selectivity. Brain Res. 1087 (2006) 1-14
3. Benyo Z., Gille A., Kero J., Csiky M., Suchankova M.C., Nusing R.M., Moers A., Pfeffer K., and Offermanns S. GPR109A (PUMA-G/HM74A) mediates nicotinic acid-induced flushing. J. Clin. Invest. 115 (2005) 3634-3640
4. Benyo Z., Gille A., Bennett C.L., Clausen B.E., and Offermanns S. Nicotinic acid-induced flushing is mediated by activation of epidermal langerhans cells. Mol. Pharmacol. 70 (2006) 1844-1849
5. Birkenbach M., Josefsen K., Yalamanchili R., Lenoir G., and Kieff E. Epstein-Barr virus-induced genes: First lymphocyte-specific G protein-coupled peptide receptors. J. Virol. 67 (1993) 2209-2220
6. Brailoiu E., Dun S.L., Brailoiu G.C., Mizuo K., Sklar L.A., Oprea T.I., Prossnitz E.R., and Dun N.J. Distribution and characterization of estrogen receptor G protein-coupled receptor 30 in the rat central nervous system. J. Endocrinol. 193 (2007) 311-321
7. Butcher R.W., and Carlson L.A. Effects of secretin on fat mobilizing lipolysis and cyclic AMP levels in rat adipose tissue. Acta Physiol. Scand. 79 (1970) 559-563
8. Calver A.R., Medhurst A.D., Robbins M.J., Charles K.J., Evans M.L., Harrison D.C., Stammers M., Hughes S.A., Hervieu G., Couve A., et al. The expression of GABA(B1) and GABA(B2) receptor subunits in the cNS differs from that in peripheral tissues. Neuroscience 100 (2000) 155-170
9. Carlson L.A. Nicotinic acid: The broad-spectrum lipid drug. A 50th anniversary review. J. Intern. Med. 258 (2005) 94-114
10. Chen P., Hao W., Rife L., Wang X.P., Shen D., Chen J., Ogden T., Van Boemel G.B., Wu L., Yang M., et al. A photic visual cycle of rhodopsin regeneration is dependent on Rgr. Nat. Genet. 28 (2001) 256-260
11. Cheng Z., Tu C., Rodriguez L., Chen T.H., Dvorak M.M., Margeta M., Gassmann M., Bettler B., Shoback D., and Chang W. Type B gamma-aminobutyric acid receptors modulate the function of the extracellular Ca2+-sensing receptor and cell differentiation in murine growth plate chondrocytes. Endocrinology 148 (2007) 4984-4992
12. Chiu M.I., Zack D.J., Wang Y., and Nathans J. Murine and bovine blue cone pigment genes: Cloning and characterization of two new members of the S family of visual pigments. Genomics 21 (1994) 440-443
13. Cohen A.I., Todd R.D., Harmon S., and O'Malley K.L. Photoreceptors of mouse retinas possess D4 receptors coupled to adenylate cyclase. Proc. Natl. Acad. Sci. USA 89 (1992) 12093-12097
14. Collins S.R., Kemmeren P., Zhao X.C., Greenblatt J.F., Spencer F., Holstege F.C., Weissman J.S., and Krogan N.J. Toward a comprehensive atlas of the physical interactome of Saccharomyces cerevisiae. Mol. Cell. Proteomics 6 (2007) 439-450
15. Collins S.R., Miller K.M., Maas N.L., Roguev A., Fillingham J., Chu C.S., Schuldiner M., Gebbia M., Recht J., Shales M., et al. Functional dissection of protein complexes involved in yeast chromosome biology using a genetic interaction map. Nature 446 (2007) 806-810
16. Connolly A.J., Ishihara H., Kahn M.L., Farese Jr. R.V., and Coughlin S.R. Role of the thrombin receptor in development and evidence for a second receptor. Nature 381 (1996) 516-519
17. Date Y., Mondal M.S., Matsukura S., Ueta Y., Yamashita H., Kaiya H., Kangawa K., and Nakazato M. Distribution of orexin/hypocretin in the rat median eminence and pituitary. Brain Res. Mol. Brain Res. 76 (2000) 1-6
18. Dryja T.P., McGee T.L., Berson E.L., Fishman G.A., Sandberg M.A., Alexander K.R., Derlacki D.J., and Rajagopalan A.S. Night blindness and abnormal cone electroretinogram ON responses in patients with mutations in the GRM6 gene encoding mGluR6. Proc. Natl. Acad. Sci. USA 102 (2005) 4884-4889
19. Eisen M.B., Spellman P.T., Brown P.O., and Botstein D. Cluster analysis and display of genome-wide expression patterns. Proc. Natl. Acad. Sci. USA 95 (1998) 14863-14868
20. Filliol D., Ghozland S., Chluba J., Martin M., Matthes H.W., Simonin F., Befort K., Gaveriaux-Ruff C., Dierich A., LeMeur M., et al. Mice deficient for delta- and mu-opioid receptors exhibit opposing alterations of emotional responses. Nat. Genet. 25 (2000) 195-200
21. Forni L.G., McKinnon W., Lord G.A., Treacher D.F., Peron J.M., and Hilton P.J. Circulating anions usually associated with the Krebs cycle in patients with metabolic acidosis. Crit. Care 9 (2005) R591-R595
22. Forster R., Mattis A.E., Kremmer E., Wolf E., Brem G., and Lipp M. A putative chemokine receptor, BLR1, directs B cell migration to defined lymphoid organs and specific anatomic compartments of the spleen. Cell 87 (1996) 1037-1047
23. Forster R., Schubel A., Breitfeld D., Kremmer E., Renner-Muller I., Wolf E., and Lipp M. CCR7 coordinates the primary immune response by establishing functional microenvironments in secondary lymphoid organs. Cell 99 (1999) 23-33
24. Fredriksson R., Lagerstrom M.C., Lundin L.G., and Schioth H.B. The G-protein-coupled receptors in the human genome form five main families. Phylogenetic analysis, paralogon groups, and fingerprints. Mol. Pharmacol. 63 (2003) 1256-1272
25. Fredriksson R., and Schioth H.B. The repertoire of G-protein-coupled receptors in fully sequenced genomes. Mol. Pharmacol. 67 (2005) 1414-1425
26. Gelling R.W., Du X.Q., Dichmann D.S., Romer J., Huang H., Cui L., Obici S., Tang B., Holst J.J., Fledelius C., et al. Lower blood glucose, hyperglucagonemia, and pancreatic alpha cell hyperplasia in glucagon receptor knockout mice. Proc. Natl. Acad. Sci. USA 100 (2003) 1438-1443
27. Gomeza J., Shannon H., Kostenis E., Felder C., Zhang L., Brodkin J., Grinberg A., Sheng H., and Wess J. Pronounced pharmacologic deficits in M2 muscarinic acetylcholine receptor knockout mice. Proc. Natl. Acad. Sci. USA 96 (1999) 1692-1697
28. Gotoh C., Hong Y.H., Iga T., Hishikawa D., Suzuki Y., Song S.H., Choi K.C., Adachi T., Hirasawa A., Tsujimoto G., et al. The regulation of adipogenesis through GPR120. Biochem. Biophys. Res. Commun. 354 (2007) 591-597
29. He W., Miao F.J., Lin D.C., Schwandner R.T., Wang Z., Gao J., Chen J.L., Tian H., and Ling L. Citric acid cycle intermediates as ligands for orphan G-protein-coupled receptors. Nature 429 (2004) 188-193
30. Hill C.A., Fox A.N., Pitts R.J., Kent L.B., Tan P.L., Chrystal M.A., Cravchik A., Collins F.H., Robertson H.M., and Zwiebel L.J. G protein-coupled receptors in Anopheles gambiae. Science 298 (2002) 176-178
31. Ho C., Conner D.A., Pollak M.R., Ladd D.J., Kifor O., Warren H.B., Brown E.M., Seidman J.G., and Seidman C.E. A mouse model of human familial hypocalciuric hypercalcemia and neonatal severe hyperparathyroidism. Nat. Genet. 11 (1995) 389-394
32. Hochachka P.W., and Dressendorfer R.H. Succinate accumulation in man during exercise. Eur. J. Appl. Physiol. Occup. Physiol. 35 (1976) 235-242
33. Hopkins A.L., and Groom C.R. The druggable genome. Nat. Rev. Drug Discov. 1 (2002) 727-730
34. Humbles A.A., Lloyd C.M., McMillan S.J., Friend D.S., Xanthou G., McKenna E.E., Ghiran S., Gerard N.P., Yu C., Orkin S.H., et al. A critical role for eosinophils in allergic airways remodeling. Science 305 (2004) 1776-1779
35. Incerti B., Cortese K., Pizzigoni A., Surace E.M., Varani S., Coppola M., Jeffery G., Seeliger M., Jaissle G., Bennett D.C., et al. Oa1 knock-out: New insights on the pathogenesis of ocular albinism type 1. Hum. Mol. Genet. 9 (2000) 2781-2788
36. Ito M., Oliverio M.I., Mannon P.J., Best C.F., Maeda N., Smithies O., and Coffman T.M. Regulation of blood pressure by the type 1A angiotensin II receptor gene. Proc. Natl. Acad. Sci. USA 92 (1995) 3521-3525
37. Jones K.A., Borowsky B., Tamm J.A., Craig D.A., Durkin M.M., Dai M., Yao W.J., Johnson M., Gunwaldsen C., Huang L.Y., et al. GABA(B) receptors function as a heteromeric assembly of the subunits GABA(B)R1 and GABA(B)R2. Nature 396 (1998) 674-679
38. Joost P., and Methner A. Phylogenetic analysis of 277 human G-protein-coupled receptors as a tool for the prediction of orphan receptor ligands. Genome Biol. 3 (2002) RESEARCH0063
39. Karsak M., Gaffal E., Date R., Wang-Eckhardt L., Rehnelt J., Petrosino S., Starowicz K., Steuder R., Schlicker E., Cravatt B., et al. Attenuation of allergic contact dermatitis through the endocannabinoid system. Science 316 (2007) 1494-1497
40. Kaupmann K., Malitschek B., Schuler V., Heid J., Froestl W., Beck P., Mosbacher J., Bischoff S., Kulik A., Shigemoto R., et al. GABA(B)-receptor subtypes assemble into functional heteromeric complexes. Nature 396 (1998) 683-687
41. Kelly M.A., Rubinstein M., Asa S.L., Zhang G., Saez C., Bunzow J.R., Allen R.G., Hnasko R., Ben-Jonathan N., Grandy D.K., et al. Pituitary lactotroph hyperplasia and chronic hyperprolactinemia in dopamine D2 receptor-deficient mice. Neuron 19 (1997) 103-113
42. Kim C.H., Kunkel E.J., Boisvert J., Johnston B., Campbell J.J., Genovese M.C., Greenberg H.B., and Butcher E.C. Bonzo/CXCR6 expression defines type 1-polarized T-cell subsets with extralymphoid tissue homing potential. J. Clin. Invest. 107 (2001) 595-601
43. Krebs H.A. Chemical composition of blood plasma and serum. Annu. Rev. Biochem. 19 (1950) 409-430
44. Krogan N.J., Cagney G., Yu H., Zhong G., Guo X., Ignatchenko A., Li J., Pu S., Datta N., Tikuisis A.P., et al. Global landscape of protein complexes in the yeast Saccharomyces cerevisiae. Nature 440 (2006) 637-643
45. Kumar U., Laird D., Srikant C.B., Escher E., and Patel Y.C. Expression of the five somatostatin receptor (SSTR1-5) subtypes in rat pituitary somatotrophes: Quantitative analysis by double-layer immunofluorescence confocal microscopy. Endocrinology 138 (1997) 4473-4476
46. Kuner R., Kohr G., Grunewald S., Eisenhardt G., Bach A., and Kornau H.C. Role of heteromer formation in GABAB receptor function. Science 283 (1999) 74-77
47. Kushnir M.M., Komaromy-Hiller G., Shushan B., Urry F.M., and Roberts W.L. Analysis of dicarboxylic acids by tandem mass spectrometry. High-throughput quantitative measurement of methylmalonic acid in serum, plasma, and urine. Clin. Chem. 47 (2001) 1993-2002
48. Le L.Q., Kabarowski J.H., Weng Z., Satterthwaite A.B., Harvill E.T., Jensen E.R., Miller J.F., and Witte O.N. Mice lacking the orphan G protein-coupled receptor G2A develop a late-onset autoimmune syndrome. Immunity 14 (2001) 561-571
49. Liberles S.D., and Buck L.B. A second class of chemosensory receptors in the olfactory epithelium. Nature 442 (2006) 645-650
50. Lin S.C., Lin C.R., Gukovsky I., Lusis A.J., Sawchenko P.E., and Rosenfeld M.G. Molecular basis of the little mouse phenotype and implications for cell type-specific growth. Nature 364 (1993) 208-213
51. Lindemann L., Meyer C.A., Jeanneau K., Bradaia A., Ozmen L., Bluethmann H., Bettler B., Wettstein J.G., Borroni E., Moreau J.L., et al. Trace amine-associated receptor 1 modulates dopaminergic activity. J. Pharmacol. Exp. Ther. 324 (2008) 948-956
52. Liu Y., Wada R., Yamashita T., Mi Y., Deng C.X., Hobson J.P., Rosenfeldt H.M., Nava V.E., Chae S.S., Lee M.J., et al. Edg-1, the G protein-coupled receptor for sphingosine-1-phosphate, is essential for vascular maturation. J. Clin. Invest. 106 (2000) 951-961
53. Lorsignol A., Vande Vijver V., Ramaekers D., Vankelecom H., and Denef C. Detection of melanocortin-3 receptor mRNA in immature rat pituitary: Functional relation to gamma3-MSH-induced changes in intracellular Ca2+ concentration?. J. Neuroendocrinol. 11 (1999) 171-179
54. Lovenberg T.W., Baron B.M., de Lecea L., Miller J.D., Prosser R.A., Rea M.A., Foye P.E., Racke M., Slone A.L., Siegel B.W., et al. A novel adenylyl cyclase-activating serotonin receptor (5-HT7) implicated in the regulation of mammalian circadian rhythms. Neuron 11 (1993) 449-458
55. Malone M.H., Wang Z., and Distelhorst C.W. The glucocorticoid-induced gene tdag8 encodes a pro-apoptotic G protein-coupled receptor whose activation promotes glucocorticoid-induced apoptosis. J. Biol. Chem. 279 (2004) 52850-52859
56. Marsh D.J., Hollopeter G., Kafer K.E., and Palmiter R.D. Role of the Y5 neuropeptide Y receptor in feeding and obesity. Nat. Med. 4 (1998) 718-721
57. Mazella J., Botto J.M., Guillemare E., Coppola T., Sarret P., and Vincent J.P. Structure, functional expression, and cerebral localization of the levocabastine-sensitive neurotensin/neuromedin N receptor from mouse brain. J. Neurosci. 16 (1996) 5613-5620
58. McGee J., Goodyear R.J., McMillan D.R., Stauffer E.A., Holt J.R., Locke K.G., Birch D.G., Legan P.K., White P.C., Walsh E.J., et al. The very large G-protein-coupled receptor VLGR1: A component of the ankle link complex required for the normal development of auditory hair bundles. J. Neurosci. 26 (2006) 6543-6553
59. Moreno F.J., Mills I., Garcia-Sainz J.A., and Fain J.N. Effects of pertussis toxin treatment on the metabolism of rat adipocytes. J. Biol. Chem. 258 (1983) 10938-10943
60. Moskowitz J., and Fain J.N. Hormonal regulation of lipolysis and phosphorylase activity in human fat cells. J. Clin. Invest. 48 (1969) 1802-1808
61. Muller G. Towards 3D structures of G protein-coupled receptors: A multidisciplinary approach. Curr. Med. Chem. 7 (2000) 861-888
62. Nagasawa T., Hirota S., Tachibana K., Takakura N., Nishikawa S., Kitamura Y., Yoshida N., Kikutani H., and Kishimoto T. Defects of B-cell lymphopoiesis and bone-marrow myelopoiesis in mice lacking the CXC chemokine PBSF/SDF-1. Nature 382 (1996) 635-638
63. Nathans J., and Hogness D.S. Isolation, sequence analysis, and intron-exon arrangement of the gene encoding bovine rhodopsin. Cell 34 (1983) 807-814
64. Nordmann J., and Nordmann R. Organic acids in blood and urine. Adv. Clin. Chem. 4 (1961) 53-120
65. Peirson S.N., Butler J.N., and Foster R.G. Experimental validation of novel and conventional approaches to quantitative real-time PCR data analysis. Nucleic Acids Res. 31 (2003) e73
66. Popova N.K., Naumenko V.S., and Plyusnina I.Z. Involvement of brain serotonin 5-HT1A receptors in genetic predisposition to aggressive behavior. Neurosci. Behav. Physiol. 37 (2007) 631-635
67. Rao S., Garrett-Sinha L.A., Yoon J., and Simon M.C. The Ets factors PU.1 and Spi-B regulate the transcription in vivo of P2Y10, a lymphoid restricted heptahelical receptor. J. Biol. Chem. 274 (1999) 34245-34252
68. Regard J.B., Kataoka H., Cano D.A., Camerer E., Yin L., Zheng Y.W., Scanlan T.S., Hebrok M., and Coughlin S.R. Probing cell type-specific functions of G(i) in vivo identifies GPCR regulators of insulin secretion. J. Clin. Invest. 117 (2007) 4034-4043
69. Rodbell M. Metabolism of isolated fat cells. I. Effects of hormones on hlucose metabolism and lipolysis. J. Biol. Chem. 239 (1964) 375-380
70. Sadagopan N., Li W., Roberds S.L., Major T., Preston G.M., Yu Y., and Tones M.A. Circulating succinate is elevated in rodent models of hypertension and metabolic disease. Am. J. Hypertens. 20 (2007) 1209-1215
71. Saiardi A., Bozzi Y., Baik J.H., and Borrelli E. Antiproliferative role of dopamine: Loss of D2 receptors causes hormonal dysfunction and pituitary hyperplasia. Neuron 19 (1997) 115-126
72. Saldanha A.J. Java Treeview-extensible visualization of microarray data. Bioinformatics 20 (2004) 3246-3248
73. Schuldiner M., Collins S.R., Thompson N.J., Denic V., Bhamidipati A., Punna T., Ihmels J., Andrews B., Boone C., Greenblatt J.F., et al. Exploration of the function and organization of the yeast early secretory pathway through an epistatic miniarray profile. Cell 123 (2005) 507-519
74. Scrocchi L.A., Brown T.J., MaClusky N., Brubaker P.L., Auerbach A.B., Joyner A.L., and Drucker D.J. Glucose intolerance but normal satiety in mice with a null mutation in the glucagon-like peptide 1 receptor gene. Nat. Med. 2 (1996) 1254-1258
75. Segre D., Deluna A., Church G.M., and Kishony R. Modular epistasis in yeast metabolism. Nat. Genet. 37 (2005) 77-83
76. Shuster D.E., Kehrli Jr. M.E., and Ackermann M.R. Neutrophilia in mice that lack the murine IL-8 receptor homolog. Science 269 (1995) 1590-1591
77. Simonin F., Gaveriaux-Ruff C., Befort K., Matthes H., Lannes B., Micheletti G., Mattei M.G., Charron G., Bloch B., and Kieffer B. kappa-Opioid receptor in humans: cDNA and genomic cloning, chromosomal assignment, functional expression, pharmacology, and expression pattern in the central nervous system. Proc. Natl. Acad. Sci. USA 92 (1995) 7006-7010
78. Sinha T.K., Thajchayapong P., Queener S.F., Allen D.O., and Bell N.H. On the lipolytic action of parathyroid hormone in man. Metabolism 25 (1976) 251-260
79. Soga T., Kamohara M., Takasaki J., Matsumoto S., Saito T., Ohishi T., Hiyama H., Matsuo A., Matsushime H., and Furuichi K. Molecular identification of nicotinic acid receptor. Biochem. Biophys. Res. Commun. 303 (2003) 364-369
80. Soto H., Wang W., Strieter R.M., Copeland N.G., Gilbert D.J., Jenkins N.A., Hedrick J., and Zlotnik A. The CC chemokine 6Ckine binds the CXC chemokine receptor CXCR3. Proc. Natl. Acad. Sci. USA 95 (1998) 8205-8210
81. Stacey M., Chang G.W., Sanos S.L., Chittenden L.R., Stubbs L., Gordon S., and Lin H.H. EMR4, a novel epidermal growth factor (EGF)-TM7 molecule up-regulated in activated mouse macrophages, binds to a putative cellular ligand on B lymphoma cell line A20. J. Biol. Chem. 277 (2002) 29283-29293
82. Sugaya T., Nishimatsu S., Tanimoto K., Takimoto E., Yamagishi T., Imamura K., Goto S., Imaizumi K., Hisada Y., Otsuka A., et al. Angiotensin II type 1a receptor-deficient mice with hypotension and hyperreninemia. J. Biol. Chem. 270 (1995) 18719-18722
83. Sun H., Gilbert D.J., Copeland N.G., Jenkins N.A., and Nathans J. Peropsin, a novel visual pigment-like protein located in the apical microvilli of the retinal pigment epithelium. Proc. Natl. Acad. Sci. USA 94 (1997) 9893-9898
84. Sun H., Macke J.P., and Nathans J. Mechanisms of spectral tuning in the mouse green cone pigment. Proc. Natl. Acad. Sci. USA 94 (1997) 8860-8865
85. Susulic V.S., Frederich R.C., Lawitts J., Tozzo E., Kahn B.B., Harper M.E., Himms-Hagen J., Flier J.S., and Lowell B.B. Targeted disruption of the beta 3-adrenergic receptor gene. J. Biol. Chem. 270 (1995) 29483-29492
86. Tsutsumi M., Zhou W., Millar R.P., Mellon P.L., Roberts J.L., Flanagan C.A., Dong K., Gillo B., and Sealfon S.C. Cloning and functional expression of a mouse gonadotropin-releasing hormone receptor. Mol. Endocrinol. 6 (1992) 1163-1169
87. Tunaru S., Kero J., Schaub A., Wufka C., Blaukat A., Pfeffer K., and Offermanns S. PUMA-G and HM74 are receptors for nicotinic acid and mediate its anti-lipolytic effect. Nat. Med. 9 (2003) 352-355
88. Valet P., Pages C., Jeanneton O., Daviaud D., Barbe P., Record M., Saulnier-Blache J.S., and Lafontan M. Alpha2-adrenergic receptor-mediated release of lysophosphatidic acid by adipocytes. A paracrine signal for preadipocyte growth. J. Clin. Invest. 101 (1998) 1431-1438
89. Varona R., Villares R., Carramolino L., Goya I., Zaballos A., Gutierrez J., Torres M., Martinez A.C., and Marquez G. CCR6-deficient mice have impaired leukocyte homeostasis and altered contact hypersensitivity and delayed-type hypersensitivity responses. J. Clin. Invest. 107 (2001) R37-R45
90. Vassilatis D.K., Hohmann J.G., Zeng H., Li F., Ranchalis J.E., Mortrud M.T., Brown A., Rodriguez S.S., Weller J.R., Wright A.C., et al. The G protein-coupled receptor repertoires of human and mouse. Proc. Natl. Acad. Sci. USA 100 (2003) 4903-4908
91. White J.H., Wise A., Main M.J., Green A., Fraser N.J., Disney G.H., Barnes A.A., Emson P., Foord S.M., and Marshall F.H. Heterodimerization is required for the formation of a functional GABA(B) receptor. Nature 396 (1998) 679-682
92. Willie J.T., Chemelli R.M., Sinton C.M., Tokita S., Williams S.C., Kisanuki Y.Y., Marcus J.N., Lee C., Elmquist J.K., Kohlmeier K.A., et al. Distinct narcolepsy syndromes in Orexin receptor-2 and Orexin null mice: Molecular genetic dissection of Non-REM and REM sleep regulatory processes. Neuron 38 (2003) 715-730
93. Wise A., Foord S.M., Fraser N.J., Barnes A.A., Elshourbagy N., Eilert M., Ignar D.M., Murdock P.R., Steplewski K., Green A., et al. Molecular identification of high and low affinity receptors for nicotinic acid. J. Biol. Chem. 278 (2003) 9869-9874
94. Wurbel M.A., Malissen M., Guy-Grand D., Meffre E., Nussenzweig M.C., Richelme M., Carrier A., and Malissen B. Mice lacking the CCR9 CC-chemokine receptor show a mild impairment of early T- and B-cell development and a reduction in T-cell receptor gammadelta(+) gut intraepithelial lymphocytes. Blood 98 (2001) 2626-2632