Agonists at GPR119 mediate secretion of GLP-1 from mouse enteroendocrine cells through glucose-independent pathways

British Journal of Pharmacology

Volumn 165, Issue 8, 2012, Pages 2799-2807

  Lan, Hong ^a,b   Lin, H V ^a   Wang, C F ^a   Wright, M J ^a   Xu, S ^a   Kang, L ^a   Juhl, K ^a   Hedrick, J A ^a   Kowalski, T J ^a  

^a MERCK RESEARCH LABORATORIES   (United States)

^b ASTRAZENECA   (United Kingdom)

Author keywords

Calcium influx; cAMP; GLP 1; Glucose; GPR119; Insulin

Indexed keywords

AR 231453; CALCIUM CHANNEL L TYPE; G PROTEIN COUPLED RECEPTOR; GLUCAGON LIKE PEPTIDE 1; GLUCOSE; MBX 2982; N OLEOYLETHANOLAMINE; NITRENDIPINE; PROTEIN GPR119; SMALL MOLECULE TRANSPORT AGENT; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL STRAIN; CELL STRAIN GLUTAG; CELL STRAIN MIN6; CONTROLLED STUDY; ENTEROENDOCRINE CELL; GLUCOSE TOLERANCE TEST; HORMONE RELEASE; IN VIVO STUDY; INSULIN RELEASE; L CELL; MALE; MOLECULAR MECHANICS; MOUSE; NONHUMAN; PANCREAS ISLET BETA CELL; PRIORITY JOURNAL; PROTEIN SECRETION; PROTEIN SYNTHESIS INHIBITION; SIGNAL TRANSDUCTION;

ANIMALS; CALCIUM; CELL LINE; COLON; ENTEROENDOCRINE CELLS; FORSKOLIN; GLUCAGON-LIKE PEPTIDE 1; GLUCOSE; INSULIN-SECRETING CELLS; MALE; MICE; MICE, INBRED C57BL; OLEIC ACIDS; RECEPTORS, G-PROTEIN-COUPLED;

EID: 84859069133     PISSN: 00071188     EISSN: 14765381     Source Type: Journal    
DOI: 10.1111/j.1476-5381.2011.01754.x     Document Type: Article

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