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Volumn 26, Issue 7, 2011, Pages 1680-1683

GPRC6A mediates responses to osteocalcin in β-cells in vitro and pancreas in vivo

Author keywords

GPCR; GPRC6A; Insulin; Osteocalcin receptor; Pancreatic cells

Indexed keywords

G PROTEIN COUPLED RECEPTOR KINASE 6; OSTEOCALCIN; POLYCYSTIN 1;

EID: 79959507054     PISSN: 08840431     EISSN: 15234681     Source Type: Journal    
DOI: 10.1002/jbmr.390     Document Type: Article
Times cited : (202)

References (20)
  • 1
    • 0025723423 scopus 로고
    • Impairment of gamma carboxylation of circulating osteocalcin (bone gla protein) in elderly women
    • Plantalech L, Guillaumont M, Vergnaud P, Leclercq M, Delmas PD,. Impairment of gamma carboxylation of circulating osteocalcin (bone gla protein) in elderly women. J Bone Miner Res. 1991; 6: 1211-1216.
    • (1991) J Bone Miner Res. , vol.6 , pp. 1211-1216
    • Plantalech, L.1    Guillaumont, M.2    Vergnaud, P.3    Leclercq, M.4    Delmas, P.D.5
  • 2
    • 77955082747 scopus 로고    scopus 로고
    • Insulin-receptor signaling in osteoblasts regulates postnatal bone acquisition and body composition
    • Fulzele K, Riddle RC, DiGirolamo DJ, et al. Insulin-receptor signaling in osteoblasts regulates postnatal bone acquisition and body composition. Cell. 2010; 142: 309-219.
    • (2010) Cell. , vol.142 , pp. 309-219
    • Fulzele, K.1    Riddle, R.C.2    Digirolamo, D.J.3
  • 3
    • 77955035304 scopus 로고    scopus 로고
    • Insulin signaling in osteoblasts integrates bone remodeling and energy metabolism
    • Ferron M, Wei J, Yoshizawa T, et al. Insulin signaling in osteoblasts integrates bone remodeling and energy metabolism. Cell. 2010; 142: 296-308.
    • (2010) Cell. , vol.142 , pp. 296-308
    • Ferron, M.1    Wei, J.2    Yoshizawa, T.3
  • 6
    • 0032588353 scopus 로고    scopus 로고
    • GABA(B) receptors make it to the top - As dimers
    • DOI 10.1016/S0165-6147(99)01323-1, PII S0165614799013231
    • Mohler H, Fritschy JM,. GABAB receptors make it to the top-as dimers. Trends Pharmacol Sci. 1999; 20: 87-89. (Pubitemid 29306929)
    • (1999) Trends in Pharmacological Sciences , vol.20 , Issue.3 , pp. 87-89
    • Mohler, H.1    Fritschy, J.-M.2
  • 7
    • 0029187946 scopus 로고
    • The metabotropic glutamate receptors: Structure and functions
    • Pin JP, Duvoisin R,. The metabotropic glutamate receptors: structure and functions. Neuropharmacology. 1995; 34: 1-26.
    • (1995) Neuropharmacology. , vol.34 , pp. 1-26
    • Pin, J.P.1    Duvoisin, R.2
  • 10
    • 19244382287 scopus 로고    scopus 로고
    • Sequence and expression pattern of a novel human orphan G-protein- coupled receptor, GPRC5B, a family C receptor with a short amino-terminal domain
    • DOI 10.1006/geno.2000.6164
    • Brauner-Osborne H, Krogsgaard-Larsen P,. Sequence and expression pattern of a novel human orphan G-protein-coupled receptor, GPRC5B, a family C receptor with a short amino-terminal domain. Genomics. 2000; 65: 121-128. (Pubitemid 30314419)
    • (2000) Genomics , vol.65 , Issue.2 , pp. 121-128
    • Brauner-Osborne, H.1    Krogsgaard-Larsen, P.2
  • 12
    • 17444394482 scopus 로고    scopus 로고
    • Cloning and characterization of a Family C orphan G-protein coupled receptor
    • DOI 10.1111/j.1471-4159.2005.03025.x
    • Kuang D, Yao Y, Lam J, Tsushima RG, Hampson DR,. Cloning and characterization of a family C orphan G-protein coupled receptor. J Neurochem. 2005; 93: 383-391. (Pubitemid 40547495)
    • (2005) Journal of Neurochemistry , vol.93 , Issue.2 , pp. 383-391
    • Kuang, D.1    Yao, Y.2    Lam, J.3    Tsushima, R.G.4    Hampson, D.R.5
  • 13
    • 2942519523 scopus 로고    scopus 로고
    • Molecular cloning, expression, and sequence analysis of GPRC6A, a novel family C G-protein-coupled receptor
    • DOI 10.1016/j.gene.2004.03.003, PII S0378111904001490
    • Wellendorph P, Brauner-Osborne H,. Molecular cloning, expression, and sequence analysis of GPRC6A, a novel family C G-protein-coupled receptor. Gene. 2004; 335: 37-46. (Pubitemid 38759751)
    • (2004) Gene , vol.335 , Issue.1-2 , pp. 37-46
    • Wellendorph, P.1    Brauner-Osborne, H.2
  • 14
    • 57349197966 scopus 로고    scopus 로고
    • GPRC6A null mice exhibit osteopenia, feminization and metabolic syndrome
    • Pi M, Chen L, Huang MZ, et al. GPRC6A null mice exhibit osteopenia, feminization and metabolic syndrome. PLoS ONE. 2008; 3: e3858.
    • (2008) PLoS ONE. , vol.3
    • Pi, M.1    Chen, L.2    Huang, M.Z.3
  • 16
    • 42449096306 scopus 로고    scopus 로고
    • Osteocalcin differentially regulates β cell and adipocyte gene expression and affects the development of metabolic diseases in wild-type mice
    • DOI 10.1073/pnas.0711119105
    • Ferron M, Hinoi E, Karsenty G, Ducy P,. Osteocalcin differentially regulates beta cell and adipocyte gene expression and affects the development of metabolic diseases in wild-type mice. Proc Natl Acad Sci U S A. 2008; 105: 5266-5270. (Pubitemid 351738545)
    • (2008) Proceedings of the National Academy of Sciences of the United States of America , vol.105 , Issue.13 , pp. 5266-5270
    • Ferron, M.1    Hinoi, E.2    Karsenty, G.3    Ducy, P.4
  • 17
    • 14944341203 scopus 로고    scopus 로고
    • Deorphanization of GPRC6A: A promiscuous L-α-amino acid receptor with preference for basic amino acids
    • DOI 10.1124/mol.104.007559
    • Wellendorph P, Hansen KB, Balsgaard A, Greenwood JR, Egebjerg J, Brauner-Osborne H,. Deorphanization of GPRC6A: a promiscuous L-alpha-amino acid receptor with preference for basic amino acids. Mol Pharmacol. 2005; 67: 589-597. (Pubitemid 40365305)
    • (2005) Molecular Pharmacology , vol.67 , Issue.3 , pp. 589-597
    • Wellendorph, P.1    Hansen, K.B.2    Balsgaard, A.3    Greenwood, J.R.4    Egebjerg, J.5    Brauner-Osborne, H.6
  • 18
    • 0032837888 scopus 로고    scopus 로고
    • Evidence that conditionally immortalized human osteoblasts express an osteocalcin receptor
    • DOI 10.1016/S8756-3282(99)00213-6, PII S8756328299002136
    • Bodine PV, Komm BS,. Evidence that conditionally immortalized human osteoblasts express an osteocalcin receptor. Bone. 1999; 25: 535-543. (Pubitemid 29469459)
    • (1999) Bone , vol.25 , Issue.5 , pp. 535-543
    • Bodine, P.V.N.1    Komm, B.S.2
  • 19
    • 0036314198 scopus 로고    scopus 로고
    • Granuphilin modulates the exocytosis of secretory granules through interaction with syntaxin 1a
    • DOI 10.1128/MCB.22.15.5518-5526.2002
    • Torii S, Zhao S, Yi Z, Takeuchi T, Izumi T,. Granuphilin modulates the exocytosis of secretory granules through interaction with syntaxin 1a. Mol Cell Biol. 2002; 22: 5518-5526. (Pubitemid 34755761)
    • (2002) Molecular and Cellular Biology , vol.22 , Issue.15 , pp. 5518-5526
    • Torii, S.1    Zhao, S.2    Yi, Z.3    Takeuchi, T.4    Izumi, T.5
  • 20
    • 58249087541 scopus 로고    scopus 로고
    • Regulation of PKD by the MAPK p38delta in insulin secretion and glucose homeostasis
    • Sumara G, Formentini I, Collins S, et al. Regulation of PKD by the MAPK p38delta in insulin secretion and glucose homeostasis. Cell. 2009; 136: 235-248.
    • (2009) Cell. , vol.136 , pp. 235-248
    • Sumara, G.1    Formentini, I.2    Collins, S.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.