메뉴 건너뛰기




Volumn 3, Issue FEB, 2012, Pages

The succinate receptor as a novel therapeutic target for oxidative and metabolic stress-related conditions

Author keywords

Diabetes mellitus; GPCR; GPR91; Oxidative stress; Renal disease; Rennin; Succinate; SUCNR1

Indexed keywords


EID: 84864570953     PISSN: None     EISSN: 16642392     Source Type: Journal    
DOI: 10.3389/fendo.2012.00022     Document Type: Review
Times cited : (156)

References (40)
  • 3
    • 20044376702 scopus 로고    scopus 로고
    • The pathobiol-ogy of diabetic complications: a unifying mechanism
    • Brownlee, M. (2005). The pathobiol-ogy of diabetic complications: a unifying mechanism. Diabetes 54, 1615-1625.
    • (2005) Diabetes , vol.54 , pp. 1615-1625
    • Brownlee, M.1
  • 6
    • 33947651719 scopus 로고    scopus 로고
    • Resi-dent dendritic cells are the predomi-nant TNF-secreting cell in early renal ischemia-reperfusion injury
    • Dong, X., Swaminathan, S., Bachman, L. A., Croatt, A. J., Nath, K. A., and Griffin, M. D. (2007). Resi-dent dendritic cells are the predomi-nant TNF-secreting cell in early renal ischemia-reperfusion injury. Kidney Int. 71, 619-628.
    • (2007) Kidney Int , vol.71 , pp. 619-628
    • Dong, X.1    Swaminathan, S.2    Bachman, L.A.3    Croatt, A.J.4    Nath, K.A.5    Griffin, M.D.6
  • 7
    • 33744979253 scopus 로고    scopus 로고
    • Nonezymatic formation of succi-nate in mitochondria under oxida-tive stress
    • Fedotcheva, N. I., Sokolov, A. P., and Kondrashova, M. N. (2006). Nonezymatic formation of succi-nate in mitochondria under oxida-tive stress. Free Radic. Biol. Med. 41, 56-64.
    • (2006) Free Radic. Biol. Med. , vol.41 , pp. 56-64
    • Fedotcheva, N.I.1    Sokolov, A.P.2    Kondrashova, M.N.3
  • 8
    • 0031819666 scopus 로고    scopus 로고
    • Tricarboxylic acid cycle intermediate pool size and estimated cycle flux in human muscle during exercise
    • Gibala, M. J., MacLean, D. A., Gra-ham, T. E., and Saltin, B. (1998). Tricarboxylic acid cycle intermediate pool size and estimated cycle flux in human muscle during exercise. Am. J. Physiol. 275, E235-E242.
    • (1998) Am. J. Physiol. , vol.275
    • Gibala, M.J.1    MacLean, D.A.2    Gra-ham, T.E.3    Saltin, B.4
  • 12
    • 0014870775 scopus 로고
    • Effects of ischaemia on content of metabolites in rat liver and kidney in-vivo
    • Hems, D. A., and Brosnan, J. T. (1970). Effects of ischaemia on content of metabolites in rat liver and kidney in-vivo. Biochem. J. 120, 105.
    • (1970) Biochem. J. , vol.120 , pp. 105
    • Hems, D.A.1    Brosnan, J.T.2
  • 14
    • 79251578024 scopus 로고    scopus 로고
    • Succi-nate independently stimulates full platelet activation via cAMP and phosphoinositide 3-kinase-beta sig-naling
    • Hogberg, C., Gidlof, O., Tan, C., Svens-son, S., Nilsson-Ohman, J., Erlinge, D., and Olde, B. (2011). Succi-nate independently stimulates full platelet activation via cAMP and phosphoinositide 3-kinase-beta sig-naling. J. Thromb. Haemost. 9, 361-372.
    • (2011) J. Thromb. Haemost. , vol.9 , pp. 361-372
    • Hogberg, C.1    Gidlof, O.2    Tan, C.3    Svens-son, S.4    Nilsson-Ohman, J.5    Erlinge, D.6    Olde, B.7
  • 15
    • 3242793421 scopus 로고    scopus 로고
    • The role of mitochondria in ischemia//reperfusion injury in organ transplantation
    • Jassem, W., and Heaton, N. D. (2004). The role of mitochondria in ischemia//reperfusion injury in organ transplantation. Kidney Int. 66, 514-517.
    • (2004) Kidney Int , vol.66 , pp. 514-517
    • Jassem, W.1    Heaton, N.D.2
  • 16
    • 0037223063 scopus 로고    scopus 로고
    • Regulation of g protein-coupled receptor kinases and arrestins during receptor desen-sitization
    • Kohout, T. A., and Lefkowitz, R. J. (2003). Regulation of g protein-coupled receptor kinases and arrestins during receptor desen-sitization. Mol. Pharmacol. 63, 9-18.
    • (2003) Mol. Pharmacol. , vol.63 , pp. 9-18
    • Kohout, T.A.1    Lefkowitz, R.J.2
  • 17
    • 0014724544 scopus 로고
    • Rate control of the tricarboxylic acid cycle
    • Krebs, H. A. (1970). Rate control of the tricarboxylic acid cycle. Adv. Enzyme Regul. 8, 335-353.
    • (1970) Adv. Enzyme Regul. , vol.8 , pp. 335-353
    • Krebs, H.A.1
  • 18
    • 0034781986 scopus 로고    scopus 로고
    • Analysis of dicarboxylic acids by tandem mass spectrometry. High-throughput quantitative measurement of methylmalonic acid in serum, plasma, and urine
    • Kushnir, M. M., Komaromy-Hiller, G., Shushan, B., Urry, F. M., and Roberts, W. L. (2001). Analysis of dicarboxylic acids by tandem mass spectrometry. High-throughput quantitative measurement of methylmalonic acid in serum, plasma, and urine. Clin. Chem. 47, 1993-2002.
    • (2001) Clin. Chem. , vol.47 , pp. 1993-2002
    • Kushnir, M.M.1    Komaromy-Hiller, G.2    Shushan, B.3    Urry, F.M.4    Roberts, W.L.5
  • 21
    • 1242317685 scopus 로고    scopus 로고
    • The SLC13 gene family of sodium sulphate/carboxylate cotransporters
    • Markovich, D., and Murer, H (2004). The SLC13 gene family of sodium sulphate/carboxylate cotransporters. Pflugers Arch. 447, 594-602.
    • (2004) Pflugers Arch , vol.447 , pp. 594-602
    • Markovich, D.1    Murer, H.2
  • 22
    • 35648940290 scopus 로고    scopus 로고
    • Transporter-mediated uptake into cellular compartments
    • Oswald, S., Grube, M., Siegmund, W., and Kroemer, H. K. (2007). Transporter-mediated uptake into cellular compartments. Xenobiotica 37, 1171-1195.
    • (2007) Xenobiotica , vol.37 , pp. 1171-1195
    • Oswald, S.1    Grube, M.2    Siegmund, W.3    Kroemer, H.K.4
  • 23
    • 29944444676 scopus 로고    scopus 로고
    • Molecular proper-ties of the SLC13 family of dicar-boxylate and sulfate transporters
    • Pajor, A. M. (2006). Molecular proper-ties of the SLC13 family of dicar-boxylate and sulfate transporters. Pflugers Arch. 451, 597-605.
    • (2006) Pflugers Arch , vol.451 , pp. 597-605
    • Pajor, A.M.1
  • 24
    • 52449104845 scopus 로고    scopus 로고
    • Activation of the renal renin-angiotensin system in diabetes -new concepts
    • Peti-Peterdi, J., Kang, J. J., and Toma, I. (2008).Activation of the renal renin-angiotensin system in diabetes -new concepts. Nephrol. Dial. Transplant. 23, 3047-3049.
    • (2008) Nephrol. Dial. Transplant. , vol.23 , pp. 3047-3049
    • Peti-Peterdi, J.1    Kang, J.J.2    Toma, I.3
  • 25
    • 54549087794 scopus 로고    scopus 로고
    • Anatomical pro-filing of G protein-coupled receptor expression
    • Regard, J. B., Sato, I. T., and Cough-lin, S. R. (2008). Anatomical pro-filing of G protein-coupled receptor expression. Cell 135, 561-571.
    • (2008) Cell , vol.135 , pp. 561-571
    • Regard, J.B.1    Sato, I.T.2    Cough-lin, S.R.3
  • 26
    • 71149117826 scopus 로고    scopus 로고
    • Local-ization of the succinate receptor in the distal nephron and its signaling in polarized MDCK cells
    • Robben,J. H.,Fenton,R.A.,Vargas,S. L., Schweer, H., Peti-Peterdi, J., Deen, P. M., and Milligan, G. (2009). Local-ization of the succinate receptor in the distal nephron and its signaling in polarized MDCK cells. Kidney Int. 76, 1258-1267.
    • (2009) Kidney Int , vol.76 , pp. 1258-1267
    • Robben, J.H.1    Fenton, R.A.2    Vargas, S.L.3    Schweer, H.4    Peti-Peterdi, J.5    Deen, P.M.6    Milligan, G.7
  • 27
    • 70349735841 scopus 로고    scopus 로고
    • Review article: kidney den-dritic cells: their role in homeostasis, inflammation and transplantation
    • Rogers,N. M.,Matthews,T. J.,Kausman, J. Y., Kitching, A. R., and Coates, P. T. (2009). Review article: kidney den-dritic cells: their role in homeostasis, inflammation and transplantation. Nephrology (Carlton) 14, 625-635.
    • (2009) Nephrology (Carlton) , vol.14 , pp. 625-635
    • Rogers, N.M.1    Matthews, T.J.2    Kausman, J.Y.3    Kitching, A.R.4    Coates, P.T.5
  • 34
    • 70449484613 scopus 로고    scopus 로고
    • The evolving story of the RAAS in hypertension, diabetes and CV dis-ease: moving from macrovascular to microvascular targets
    • Steckelings, U. M., Rompe, F., Kaschina, E., and Unger, T. (2009). The evolving story of the RAAS in hypertension, diabetes and CV dis-ease: moving from macrovascular to microvascular targets. Fundam. Clin. Pharmacol. 23, 693-703.
    • (2009) Fundam. Clin. Pharmacol. , vol.23 , pp. 693-703
    • Steckelings, U.M.1    Rompe, F.2    Kaschina, E.3    Unger, T.4
  • 36
    • 38149059911 scopus 로고    scopus 로고
    • Mitochondria and cellular oxygen sensing in the HIF pathway
    • Taylor, C. T. (2008). Mitochondria and cellular oxygen sensing in the HIF pathway. Biochem. J. 409, 19-26.
    • (2008) Biochem. J. , vol.409 , pp. 19-26
    • Taylor, C.T.1
  • 37
    • 46749087465 scopus 로고    scopus 로고
    • Suc-cinate receptor GPR91 provides a direct link between high glucose lev-els and renin release in murine and rabbit kidney
    • Toma, I., Kang, J. J., Sipos, A., Var-gas, S., Bansal, E., Hanner, F., Meer, E., and Peti-Peterdi, J. (2008). Suc-cinate receptor GPR91 provides a direct link between high glucose lev-els and renin release in murine and rabbit kidney. J. Clin. Invest. 118, 2526-2534.
    • (2008) J. Clin. Invest. , vol.118 , pp. 2526-2534
    • Toma, I.1    Kang, J.J.2    Sipos, A.3    Var-gas, S.4    Bansal, E.5    Hanner, F.6    Meer, E.7    Peti-Peterdi, J.8
  • 38
    • 65649111290 scopus 로고    scopus 로고
    • Activation of the succinate receptor GPR91 in macula densa cells causes renin release
    • Vargas, S. L., Toma, I., Kang, J. J., Meer, E. J., and Peti-Peterdi, J. (2009). Activation of the succinate receptor GPR91 in macula densa cells causes renin release. J. Am. Soc. Nephrol. 20, 1002-1011.
    • (2009) J. Am. Soc. Nephrol. , vol.20 , pp. 1002-1011
    • Vargas, S.L.1    Toma, I.2    Kang, J.J.3    Meer, E.J.4    Peti-Peterdi, J.5
  • 39
    • 0034646270 scopus 로고    scopus 로고
    • Mitochondrial dysfunction during hypoxia/reoxygenation and its correction by anaerobic metab-olism of citric acid cycle intermedi-ates
    • Weinberg, J. M., Venkatachalam, M. A., Roeser, N. F., and Nissim, I. (2000). Mitochondrial dysfunction during hypoxia/reoxygenation and its correction by anaerobic metab-olism of citric acid cycle intermedi-ates. Proc. Natl. Acad. Sci. U.S.A. 97, 2826-2831.
    • (2000) Proc. Natl. Acad. Sci. U. S. A. , vol.97 , pp. 2826-2831
    • Weinberg, J.M.1    Venkatachalam, M.A.2    Roeser, N.F.3    Nissim, I.4
  • 40
    • 0035970294 scopus 로고    scopus 로고
    • An expressed sequence tag (EST) data mining strategy succeeding in the discovery of new G-protein coupled receptors
    • Wittenberger, T., Schaller, H. C., and Hellebrand, S. (2001). An expressed sequence tag (EST) data mining strategy succeeding in the discovery of new G-protein coupled receptors. J. Mol. Biol. 307, 799-813
    • (2001) J. Mol. Biol. , vol.307 , pp. 799-813
    • Wittenberger, T.1    Schaller, H.C.2    Hellebrand, S.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.