Peroxisome proliferator-activated receptor γ regulates expression of the anti-lipolytic G-protein-coupled receptor 81 (GPR81/Gpr81)

Journal of Biological Chemistry

Volumn 284, Issue 39, 2009, Pages 26385-26393

  Jeninga, Ellen H ^a,b   Bugge, Anne ^c   Nielsen, Ronni ^c   Kersten, Sander ^d   Hamers, Nicole ^a,b   Dani, Christian ^e   Wabitsch, Martin ^f   Berger, Ruud ^a,b   Stunneberg, Hendrik G ^g   Mandrup, Susanne ^c   Kalkhoven, Eric ^a,b  

^a UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

^b NETHERLANDS METABOLOMICS CENTRE   (Netherlands)

^c UNIVERSITY OF SOUTHERN DENMARK   (Denmark)

^d WAGENINGEN UNIVERSITY   (Netherlands)

^e UNIVERSITÉ CÔTE D'AZUR   (France)

^f UNIVERSITY OF ULM   (Germany)

^g RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

3T3-L1 ADIPOCYTES; ADIPOCYTES; CHROMATIN IMMUNOPRECIPITATION; ELECTROMOBILITY; FREE FATTY ACID; G PROTEIN COUPLED RECEPTORS; IN-VIVO; INHIBITORY EFFECT; INSULIN RESISTANCE; LIPOLYTIC; MOLECULAR TARGETS; MRNA EXPRESSION; NUCLEAR RECEPTORS; PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR; PROTEIN EXPRESSIONS; REPORTER ASSAY; RETINOID X RECEPTOR; ROSIGLITAZONE; SEQUENCING ANALYSIS; SMALL INTERFERING RNA; TARGET GENES;

ACID RESISTANCE; ACIDS; ASSAYS; BINDING ENERGY; BINDING SITES; CYTOLOGY; FATTY ACIDS; INSULIN; NUCLEIC ACIDS; RNA; TARGETS; WELL STIMULATION;

GENES;

2,4 THIAZOLIDINEDIONE DERIVATIVE; CELL NUCLEUS RECEPTOR; FATTY ACID; G PROTEIN COUPLED RECEPTOR 109A; G PROTEIN COUPLED RECEPTOR 109B; G PROTEIN COUPLED RECEPTOR 81; INSULIN SENSITIZING AGENT; MESSENGER RNA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; RECEPTOR; RETINOID X RECEPTOR; ROSIGLITAZONE; SMALL INTERFERING RNA; UNCLASSIFIED DRUG;

ADIPOCYTE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BINDING SITE; CELL DIFFERENTIATION; CELL FUNCTION; CHROMATIN IMMUNOPRECIPITATION; CONTROLLED STUDY; DRUG MECHANISM; DRUG TARGETING; EPIDIDYMIS FAT; GEL MOBILITY SHIFT ASSAY; GENE CONTROL; GENE EXPRESSION; GENE INDUCTION; GENE TARGETING; INSULIN RESISTANCE; LIPOLYSIS; MALE; MOUSE; NONHUMAN; OBESITY; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; SEQUENCE ANALYSIS;

3T3-L1 CELLS; ADIPOCYTES; ANIMALS; BASE SEQUENCE; BLOTTING, WESTERN; CELL DIFFERENTIATION; CELLS, CULTURED; CHROMATIN IMMUNOPRECIPITATION; GENE EXPRESSION REGULATION; HUMANS; MICE; MICE, INBRED STRAINS; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PPAR GAMMA; PROMOTER REGIONS, GENETIC; PROTEIN BINDING; RECEPTORS, G-PROTEIN-COUPLED; RECEPTORS, NICOTINIC; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA INTERFERENCE; SEQUENCE HOMOLOGY, NUCLEIC ACID; THIAZOLIDINEDIONES;

MURINAE; MUS;

EID: 70350400862     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M109.040741     Document Type: Article

References (53)

1. James, W. P. (2008) J. Intern. Med. 263, 336-352
2. Rosen, E. D., and Spiegelman, B. M. (2006) Nature 444, 847-853
3. Duncan, R. E., Ahmadian, M., Jaworski, K., Sarkadi-Nagy, E., and Sul, H. S. (2007) Annu. Rev. Nutr. 27, 79-101
4. Reynisdottir, S., Langin, D., Carlström, K., Holm, C., Rössner, S., and Arner, P. (1995) Clin. Sci. 89, 421-429
5. Large, V., Peroni, O., Letexier, D., Ray, H., and Beylot, M. (2004) Diabetes Metab. 30, 294-309
6. Jensen, M. D., Haymond, M. W., Rizza, R. A., Cryer, P. E., and Miles, J. M. (1989) J. Clin. Invest. 83, 1168-1173
7. Hotamisligil, G. S., Shargill, N. S., and Spiegelman, B. M. (1993) Science 259, 87-91
8. Bays, H., Mandarino, L., and DeFronzo, R. A. (2004) J. Clin. Endocrinol. Metab. 89, 463-478
9. Lehrke, M., and Lazar, M. A. (2005) Cell 123, 993-999
10. Glass, C. K., and Rosenfeld, M. G. (2000) Genes Dev. 14, 121-141
11. Lehmann, J. M., Moore, L. B., Smith-Oliver, T. A., Wilkison, W. O., Willson, T. M., and Kliewer, S. A. (1995) J. Biol. Chem. 270, 12953-12956
12. Nielsen, R., Pedersen, T. A., Hagenbeek, D., Moulos, P., Siersbaek, R., Megens, E., Denissov, S., Börgesen, M., Francoijs, K. J., Mandrup, S., and Stunnenberg, H. G. (2008) Genes Dev. 22, 2953-2967
13. Boden, G. (1997) Diabetes 46, 3-10
14. Dalen, K. T., Schoonjans, K., Ulven, S. M., Weedon-Fekjaer, M. S., Bentzen, T. G., Koutnikova, H., Auwerx, J., and Nebb, H. I. (2004) Diabetes 53, 1243-1252
15. Kershaw, E. E., Schupp, M., Guan, H. P., Gardner, N. P., Lazar, M. A., and Flier, J. S. (2007) Am. J. Physiol. Endocrinol. Metab. 293, E1736-E1745
16. Yajima, H., Kobayashi, Y., Kanaya, T., and Horino, Y. (2007) Biochem. Biophys. Res. Commun. 352, 526-531
17. Lenhard, J. M., Kliewer, S. A., Paulik, M. A., Plunket, K. D., Lehmann, J. M., and Weiel, J. E. (1997) Biochem. Pharmacol. 54, 801-808
18. Wang, P., Renes, J., Bouwman, F., Bunschoten, A., Mariman, E., and Keijer, J. (2007) Diabetologia 50, 654-665
19. McTernan, P. G., Harte, A. L., Anderson, L. A., Green, A., Smith, S. A., Holder, J. C., Barnett, A. H., Eggo, M. C., and Kumar, S. (2002) Diabetes 51, 1493-1498
20. Souza, S. C., Yamamoto, M. T., Franciosa, M. D., Lien, P., and Greenberg, A. S. (1998) Diabetes 47, 691-695
21. Okazaki, H., Osuga, J., Tamura, Y., Yahagi, N., Tomita, S., Shionoiri, F., Iizuka, Y., Ohashi, K., Harada, K., Kimura, S., Gotoda, T., Shimano, H., Yamada, N., and Ishibashi, S. (2002) Diabetes 51, 3368-3375
22. Tamori, Y., Masugi, J., Nishino, N., and Kasuga, M. (2002) Diabetes 51, 2045-2055
23. Miles, J. M., Wooldridge, D., Grellner, W. J., Windsor, S., Isley, W. L., Klein, S., and Harris, W. S. (2003) Diabetes 52, 675-681
24. Boden, G., Cheung, P., Mozzoli, M., and Fried, S. K. (2003) Metabolism 52, 753-759
25. Mayerson, A. B., Hundal, R. S., Dufour, S., Lebon, V., Befroy, D., Cline, G. W., Enocksson, S., Inzucchi, S. E., Shulman, G. I., and Petersen, K. F. (2002) Diabetes 51, 797-802
26. Racette, S. B., Davis, A. O., McGill, J. B., and Klein, S. (2002) Metabolism 51, 169-174
27. Ausubel, F. M., Brent, R., Kingston, R., Moore, D., Seidman, J. J., Smith, J., and Struhl, K. (1993) Current Protocols in Molecular Biology, John Wiley & Sons, Inc., New York
28. Jeninga, E. H., van Beekum, O., van Dijk, A. D., Hamers, N., Hendriks-Stegeman, B. I., Bonvin, A. M., Berger, R., and Kalkhoven, E. (2007) Mol. Endocrinol. 21, 1049-1065
29. Wabitsch, M., Brenner, R. E., Melzner, I., Braun, M., Möller, P., Heinze, E., Debatin, K. M., and Hauner, H. (2001) Int. J. Obes. Relat Metab. Disord. 25, 8-15
30. Rodriguez, A. M., Elabd, C., Delteil, F., Astier, J., Vernochet, C., Saint-Marc, P., Guesnet, J., Guezennec, A., Amri, E. Z., Dani, C., and Ailhaud, G. (2004) Biochem. Biophys. Res. Commun. 315, 255-263
31. Stienstra, R., Duval, C., Keshtkar, S., van der Laak, J., Kersten, S., and Müller, M. (2008) J. Biol. Chem. 283, 22620-22627
32. Nielsen, R., Grøntved, L., Stunnenberg, H. G., and Mandrup, S. (2006) Mol. Cell. Biol. 26, 5698-5714
33. Lee, D. K., Nguyen, T., Lynch, K. R., Cheng, R., Vanti, W. B., Arkhitko, O., Lewis, T., Evans, J. F., George, S. R., and O'Dowd, B. F. (2001) Gene 275, 83-91
34. Wise, A., Foord, S. M., Fraser, N. J., Barnes, A. A., Elshourbagy, N., Eilert, M., Ignar, D. M., Murdock, P. R., Steplewski, K., Green, A., Brown, A. J., Dowell, S. J., Szekeres, P. G., Hassall, D. G., Marshall, F. H., Wilson, S., and Pike, N. B. (2003) J. Biol. Chem. 278, 9869-9874
35. Tunaru, S., Kero, J., Schaub, A., Wufka, C., Blaukat, A., Pfeffer, K., and Offermanns, S. (2003) Nat. Med. 9, 352-355
36. Soga, T., Kamohara, M., Takasaki, J., Matsumoto, S., Saito, T., Ohishi, T., Hiyama, H., Matsuo, A., Matsushime, H., and Furuichi, K. (2003) Biochem. Biophys. Res. Commun. 303, 364-369
37. Schaub, A., Fütterer, A., and Pfeffer, K. (2001) Eur. J. Immunol. 31, 3714-3725
38. Ge, H., Weiszmann, J., Reagan, J. D., Gupte, J., Baribault, H., Gyuris, T., Chen, J. L., Tian, H., and Li, Y. (2008) J. Lipid Res. 49, 797-803
39. Taggart, A. K., Kero, J., Gan, X., Cai, T. Q., Cheng, K., Ippolito, M., Ren, N., Kaplan, R., Wu, K., Wu, T. J., Jin, L., Liaw, C., Chen, R., Richman, J., Connolly, D., Offermanns, S., Wright, S. D., and Waters, M. G. (2005) J. Biol. Chem. 280, 26649-26652
40. Irukayama-Tomobe, Y., Tanaka, H., Yokomizo, T., Hashidate-Yoshida, T., Yanagisawa, M., and Sakurai, T. (2009) Proc. Natl. Acad. Sci. U.S.A. 106, 3930-3934
41. Cai, T. Q., Ren, N., Jin, L., Cheng, K., Kash, S., Chen, R., Wright, S. D., Taggart, A. K., and Waters, M. G. (2008) Biochem. Biophys. Res. Commun. 377, 987-991
42. Liu, C., Wu, J., Zhu, J., Kuei, C., Yu, J., Shelton, J., Sutton, S. W., Li, X., Yun, S. J., Mirzadegan, T., Mazur, C., Kamme, F., and Lovenberg, T. W. (2009) J. Biol. Chem. 284, 2811-2822
43. Boyd, A. E., 3rd, Giamber, S. R., Mager, M., and Lebovitz, H. E. (1974) Metabolism 23, 531-542
44. De Pergola, G., Cignarelli, M., Nardelli, G., Garruti, G., Corso, M., Di Paolo, S., Cardone, F., and Giorgino, R. (1989) Horm. Metab. Res. 21, 210-213
45. Offermanns, S. (2006) Trends Pharmacol. Sci. 27, 384-390
46. Hauser, S., Adelmant, G., Sarraf, P., Wright, H. M., Mueller, E., and Spiegelman, B. M. (2000) J. Biol. Chem. 275, 18527-18533
47. Sandelin, A., and Wasserman, W. W. (2005) Mol. Endocrinol. 19, 595-606
48. Barroso, I., Gurnell, M., Crowley, V. E., Agostini, M., Schwabe, J. W., Soos, M. A., Maslen, G. L., Williams, T. D., Lewis, H., Schafer, A. J., Chatterjee, V. K., and O'Rahilly, S. (1999) Nature 402, 880-883
49. Rosen, E. D., and Spiegelman, B. M. (2001) J. Biol. Chem. 276, 37731-37734
50. Lefterova, M. I., Zhang, Y., Steger, D. J., Schupp, M., Schug, J., Cristancho, A., Feng, D., Zhuo, D., Stoeckert, C. J., Jr., Liu, X. S., and Lazar, M. A. (2008) Genes Dev. 22, 2941-2952
51. West, A. G., and Fraser, P. (2005) Hum. Mol. Genet. 14, R101-R111
52. Ge, H., Li, X., Weiszmann, J., Wang, P., Baribault, H., Chen, J. L., Tian, H., and Li, Y. (2008) Endocrinology 149, 4519-4526
53. Hong, Y. H., Nishimura, Y., Hishikawa, D., Tsuzuki, H., Miyahara, H., Gotoh, C., Choi, K. C., Feng, D. D., Chen, C., Lee, H. G., Katoh, K., Roh, S. G., and Sasaki, S. (2005) Endocrinology 146, 5092-5099