-
1
-
-
33749048568
-
Hypertension and antihypertensive treatment of diabetic nephropathy
-
Ritz E, Dikow R. Hypertension and antihypertensive treatment of diabetic nephropathy. Nat Clin Pract Nephrol 2006; 2: 562-567.
-
(2006)
Nat Clin Pract Nephrol
, vol.2
, pp. 562-567
-
-
Ritz, E.1
Dikow, R.2
-
2
-
-
37549035027
-
Diabetic nephropathy: Mechanisms of renal disease progression
-
Kanwar YS, Wada J, Sun L et al. Diabetic nephropathy: mechanisms of renal disease progression. Exp Biol Med (Maywood) 2008; 233: 4-11.
-
(2008)
Exp Biol Med (Maywood)
, vol.233
, pp. 4-11
-
-
Kanwar, Y.S.1
Wada, J.2
Sun, L.3
-
3
-
-
48249127629
-
From fibrosis to sclerosis: Mechanisms of glomerulosclerosis in diabetic nephropathy
-
Qian Y, Feldman E, Pennathur S et al. From fibrosis to sclerosis: mechanisms of glomerulosclerosis in diabetic nephropathy. Diabetes 2008; 57: 1439-1445.
-
(2008)
Diabetes
, vol.57
, pp. 1439-1445
-
-
Qian, Y.1
Feldman, E.2
Pennathur, S.3
-
4
-
-
0347511753
-
Mediators of diabetic renal disease: The case for TGF-beta as the major mediator
-
Ziyadeh FN. Mediators of diabetic renal disease: the case for TGF-beta as the major mediator. J Am Soc Nephrol 2004; 15: S55-S57.
-
(2004)
J Am Soc Nephrol
, vol.15
-
-
Ziyadeh, F.N.1
-
5
-
-
66149140626
-
Transcription factors in the pathogenesis of diabetic nephropathy
-
Sanchez AP, Sharma K. Transcription factors in the pathogenesis of diabetic nephropathy. Expert Rev Mol Med 2009; 11: e13.
-
(2009)
Expert Rev Mol Med
, vol.11
-
-
Sanchez, A.P.1
Sharma, K.2
-
6
-
-
0035922441
-
Effects of losartan on renal and cardiovascular outcomes in patients with type 2 diabetes and nephropathy
-
Brenner BM, Cooper ME, de Zeeuw D et al. Effects of losartan on renal and cardiovascular outcomes in patients with type 2 diabetes and nephropathy. N Engl J Med 2001; 345: 861-869.
-
(2001)
N Engl J Med
, vol.345
, pp. 861-869
-
-
Brenner, B.M.1
Cooper, M.E.2
De Zeeuw, D.3
-
7
-
-
34047247353
-
The renin-angiotensin system and diabetic nephropathy
-
Gurley SB, Coffman TM. The renin-angiotensin system and diabetic nephropathy. Semin Nephrol 2007; 27: 144-152.
-
(2007)
Semin Nephrol
, vol.27
, pp. 144-152
-
-
Gurley, S.B.1
Coffman, T.M.2
-
8
-
-
58049197816
-
Inhibition of the renin-angiotensin system: Is more better?
-
Anderson S, Komers R. Inhibition of the renin-angiotensin system: is more better? Kidney Int 2009; 75: 12-14.
-
(2009)
Kidney Int
, vol.75
, pp. 12-14
-
-
Anderson, S.1
Komers, R.2
-
9
-
-
0035139809
-
Ornithine decarboxylase kidney size and the tubular hypothesis of glomerular hyperfiltration in experimental diabetes
-
Thomson SC, Deng A, Bao D et al. Ornithine decarboxylase, kidney size, and the tubular hypothesis of glomerular hyperfiltration in experimental diabetes. J Clin Invest 2001; 107: 217-224.
-
(2001)
J Clin Invest
, vol.107
, pp. 217-224
-
-
Thomson, S.C.1
Deng, A.2
Bao, D.3
-
10
-
-
44349096948
-
Lack of A1 adenosine receptors augments diabetic hyperfiltration and glomerular injury
-
Faulhaber-Walter R, Chen L, Oppermann M et al. Lack of A1 adenosine receptors augments diabetic hyperfiltration and glomerular injury. J Am Soc Nephrol 2008; 19: 722-730.
-
(2008)
J Am Soc Nephrol
, vol.19
, pp. 722-730
-
-
Faulhaber-Walter, R.1
Chen, L.2
Oppermann, M.3
-
11
-
-
34250657467
-
Diabetes-induced hyperfiltration in adenosine A(1)-receptor deficient mice lacking the tubuloglomerular feedback mechanism
-
Sällström J, Carlsson PO, Fredholm BB et al. Diabetes-induced hyperfiltration in adenosine A(1)-receptor deficient mice lacking the tubuloglomerular feedback mechanism. Acta Physiol (Oxf) 2007; 190: 253-259.
-
(2007)
Acta Physiol (Oxf)
, vol.190
, pp. 253-259
-
-
Sällström, J.1
Carlsson, P.O.2
Fredholm, B.B.3
-
12
-
-
2442649129
-
Citric acid cycle intermediates as ligands for orphan G-protein-coupled receptors
-
He W, Miao FJ, Lin DC et al. Citric acid cycle intermediates as ligands for orphan G-protein-coupled receptors. Nature 2004; 429: 188-193.
-
(2004)
Nature
, vol.429
, pp. 188-193
-
-
He, W.1
Miao, F.J.2
Lin, D.C.3
-
13
-
-
46749087465
-
Succinate receptor GPR91 provides a direct link between high glucose levels and renin release in murine and rabbit kidney
-
Toma I, Kang JJ, Sipos A et al. Succinate receptor GPR91 provides a direct link between high glucose levels and renin release in murine and rabbit kidney. J Clin Invest 2008; 118: 2526-2534.
-
(2008)
J Clin Invest
, vol.118
, pp. 2526-2534
-
-
Toma, I.1
Kang, J.J.2
Sipos, A.3
-
14
-
-
65649111290
-
Activation of the succinate receptor GPR91 in macula densa cells causes renin release
-
Vargas SL, Toma I, Kang JJ et al. Activation of the succinate receptor GPR91 in macula densa cells causes renin release. J Am Soc Nephrol 2009; 20: 1002-1011.
-
(2009)
J Am Soc Nephrol
, vol.20
, pp. 1002-1011
-
-
Vargas, S.L.1
Toma, I.2
Kang, J.J.3
-
15
-
-
52449104845
-
Activation of the renal renin-angiotensin system in diabetes-new concepts
-
Peti-Peterdi J, Kang JJ, Toma I. Activation of the renal renin-angiotensin system in diabetes-new concepts. Nephrol Dial Transplant 2008; 23: 3047-3049.
-
(2008)
Nephrol Dial Transplant
, vol.23
, pp. 3047-3049
-
-
Peti-Peterdi, J.1
Kang, J.J.2
Toma, I.3
-
16
-
-
2442683201
-
Physiology: Orphan detectors of metabolism
-
Hebert SC. Physiology: orphan detectors of metabolism. Nature 2004; 429: 143-145.
-
(2004)
Nature
, vol.429
, pp. 143-145
-
-
Hebert, S.C.1
-
17
-
-
35348843343
-
Circulating succinate is elevated in rodent models of hypertension and metabolic disease
-
Sadagopan N, Li W, Roberds SL et al. Circulating succinate is elevated in rodent models of hypertension and metabolic disease. Am J Hypertens 2007; 20: 1209-1215.
-
(2007)
Am J Hypertens
, vol.20
, pp. 1209-1215
-
-
Sadagopan, N.1
Li, W.2
Roberds, S.L.3
-
18
-
-
33744979253
-
Nonenzymatic formation of succinate in mitochondria under oxidative stress
-
Fedotcheva NI, Sokolov AP, Kondrashova MN. Nonenzymatic formation of succinate in mitochondria under oxidative stress. Free Radic Biol Med 2006; 41: 56-64.
-
(2006)
Free Radic Biol Med
, vol.41
, pp. 56-64
-
-
Fedotcheva, N.I.1
Sokolov, A.P.2
Kondrashova, M.N.3
-
19
-
-
19944433653
-
Succinate links TCA cycle dysfunction to oncogenesis by inhibiting HIF-alpha prolyl hydroxylase
-
Selak MA, Armour SM, MacKenzie ED et al. Succinate links TCA cycle dysfunction to oncogenesis by inhibiting HIF-alpha prolyl hydroxylase. Cancer Cell 2005; 7: 77-85.
-
(2005)
Cancer Cell
, vol.7
, pp. 77-85
-
-
Selak, M.A.1
Armour, S.M.2
MacKenzie, E.D.3
-
20
-
-
0025697093
-
Evidence for a preglomerular oxygen diffusion shunt in rat renal cortex
-
Schurek HJ, Jost U, Baumgartl H et al. Evidence for a preglomerular oxygen diffusion shunt in rat renal cortex. Am J Physiol 1990; 259: F910-F915.
-
(1990)
Am J Physiol
, vol.259
-
-
Schurek, H.J.1
Jost, U.2
Baumgartl, H.3
-
22
-
-
25844513144
-
Oxidative stress and nitric oxide deficiency in the kidney: A critical link to hypertension?
-
Wilcox CS. Oxidative stress and nitric oxide deficiency in the kidney: a critical link to hypertension? Am J Physiol Regul Integr Comp Physiol 2005; 289: R913-R935.
-
(2005)
Am J Physiol Regul Integr Comp Physiol
, vol.289
-
-
Wilcox, C.S.1
-
23
-
-
0014724544
-
Rate control of the tricarboxylic acid cycle
-
Krebs HA. Rate control of the tricarboxylic acid cycle. Adv Enzyme Regul 1970; 8: 335-353.
-
(1970)
Adv Enzyme Regul
, vol.8
, pp. 335-353
-
-
Krebs, H.A.1
-
24
-
-
0014011226
-
Effects of changes in brain metabolism on the levels of citric acid cycle intermediates
-
Goldberg ND, Passonneau JV, Lowry OH. Effects of changes in brain metabolism on the levels of citric acid cycle intermediates. J Biol Chem 1966; 241: 3997-4003.
-
(1966)
J Biol Chem
, vol.241
, pp. 3997-4003
-
-
Goldberg, N.D.1
Passonneau, J.V.2
Lowry, O.H.3
-
25
-
-
54549087794
-
Anatomical profiling of G proteincoupled receptor expression
-
Regard JB, Sato IT, Coughlin SR. Anatomical profiling of G proteincoupled receptor expression. Cell 2008; 135: 561-571.
-
(2008)
Cell
, vol.135
, pp. 561-571
-
-
Regard, J.B.1
Sato, I.T.2
Coughlin, S.R.3
-
26
-
-
34447095853
-
Succinate is a paracrine signal for liver damage
-
Correa PR, Kruglov EA, Thompson M et al. Succinate is a paracrine signal for liver damage. J Hepatol 2007; 47: 262-269.
-
(2007)
J Hepatol
, vol.47
, pp. 262-269
-
-
Correa, P.R.1
Kruglov, E.A.2
Thompson, M.3
-
27
-
-
54549089749
-
Triggering the succinate receptor GPR91 on dendritic cells enhances immunity
-
Rubic T, Lametschwandtner G, Jost S et al. Triggering the succinate receptor GPR91 on dendritic cells enhances immunity. Nat Immunol 2008; 9: 1261-1269.
-
(2008)
Nat Immunol
, vol.9
, pp. 1261-1269
-
-
Rubic, T.1
Lametschwandtner, G.2
Jost, S.3
-
29
-
-
53549118277
-
The succinate receptor GPR91 in neurons has a major role in retinal angiogenesis
-
Sapieha P, Sirinyan M, Hamel D et al. The succinate receptor GPR91 in neurons has a major role in retinal angiogenesis. Nat Med 2008; 14: 1067-1076.
-
(2008)
Nat Med
, vol.14
, pp. 1067-1076
-
-
Sapieha, P.1
Sirinyan, M.2
Hamel, D.3
-
30
-
-
33646358954
-
High glucose blunts vascular endothelial growth factor response to hypoxia via the oxidative stressregulated hypoxia-inducible factor/hypoxia- responsible element pathway
-
Katavetin P, Miyata T, Inagi R et al. High glucose blunts vascular endothelial growth factor response to hypoxia via the oxidative stressregulated hypoxia-inducible factor/hypoxia-responsible element pathway. J Am Soc Nephrol 2006; 17: 1405-1413.
-
(2006)
J Am Soc Nephrol
, vol.17
, pp. 1405-1413
-
-
Katavetin, P.1
Miyata, T.2
Inagi, R.3
-
31
-
-
33750866706
-
Altered gene expression related to glomerulogenesis and podocyte structure in early diabetic nephropathy of db/db mice and its restoration by pioglitazone
-
Makino H, Miyamoto Y, Sawai K et al. Altered gene expression related to glomerulogenesis and podocyte structure in early diabetic nephropathy of db/db mice and its restoration by pioglitazone. Diabetes 2006; 55: 2747-2756.
-
(2006)
Diabetes
, vol.55
, pp. 2747-2756
-
-
Makino, H.1
Miyamoto, Y.2
Sawai, K.3
-
32
-
-
64549148523
-
A new mouse model resembling human diabetic nephropathy: Uncoupling of VEGF with eNOS as a novel pathogenic mechanism
-
Nakagawa T. A new mouse model resembling human diabetic nephropathy: uncoupling of VEGF with eNOS as a novel pathogenic mechanism. Clin Nephrol 2009; 71: 103-109.
-
(2009)
Clin Nephrol
, vol.71
, pp. 103-109
-
-
Nakagawa, T.1
-
33
-
-
37249086816
-
Adaptation to hypoxia in the diabetic rat kidney
-
Rosenberger C, Khamaisi M, Abassi Z et al. Adaptation to hypoxia in the diabetic rat kidney. Kidney Int 2008; 73: 34-42.
-
(2008)
Kidney Int
, vol.73
, pp. 34-42
-
-
Rosenberger, C.1
Khamaisi, M.2
Abassi, Z.3
-
34
-
-
33947520506
-
Inhibition of hypoxia-inducible factor (HIF) hydroxylases by citric acid cycle intermediates: Possible links between cell metabolism and stabilization of HIF
-
Koivunen P, Hirsilä M, Remes AM et al. Inhibition of hypoxia-inducible factor (HIF) hydroxylases by citric acid cycle intermediates: possible links between cell metabolism and stabilization of HIF. J Biol Chem 2007; 282: 4524-4532.
-
(2007)
J Biol Chem
, vol.282
, pp. 4524-4532
-
-
Koivunen, P.1
Hirsilä, M.2
Remes, A.M.3
-
35
-
-
0034924523
-
P38 MAPK and MAPK kinase 3/6 mRNA and activities are increased in early diabetic glomeruli
-
Kang SW, Adler SG, Lapage J et al. p38 MAPK and MAPK kinase 3/6 mRNA and activities are increased in early diabetic glomeruli. Kidney Int 2001; 60: 543-552.
-
(2001)
Kidney Int
, vol.60
, pp. 543-552
-
-
Kang, S.W.1
Adler, S.G.2
Lapage, J.3
-
36
-
-
0035057565
-
Immunohistochemical and functional correlations of renal cyclooxygenase-2 in experimental diabetes
-
Komers R, Lindsley JN, Oyama TT et al. Immunohistochemical and functional correlations of renal cyclooxygenase-2 in experimental diabetes. J Clin Invest 2001; 107: 889-898.
-
(2001)
J Clin Invest
, vol.107
, pp. 889-898
-
-
Komers, R.1
Lindsley, J.N.2
Oyama, T.T.3
-
37
-
-
34249017571
-
Renal p38 MAP kinase activity in experimental diabetes
-
Komers R, Lindsley JN, Oyama TT et al. Renal p38 MAP kinase activity in experimental diabetes. Lab Invest 2007; 87: 548-558.
-
(2007)
Lab Invest
, vol.87
, pp. 548-558
-
-
Komers, R.1
Lindsley, J.N.2
Oyama, T.T.3
-
38
-
-
0036423877
-
Cyclooxygenase-2 inhibitor blocks expression of mediators of renal injury in a model of diabetes and hypertension
-
Cheng H-F, Wang CJ, Moeckel GW et al. Cyclooxygenase-2 inhibitor blocks expression of mediators of renal injury in a model of diabetes and hypertension. Kidney Int 2002; 62: 929-939.
-
(2002)
Kidney Int
, vol.62
, pp. 929-939
-
-
Cheng, H.-F.1
Wang, C.J.2
Moeckel, G.W.3
-
39
-
-
71149117826
-
Localization of the succinate receptor in the distal nephron and its signaling in polarized MDCK cells
-
Robben JH, Fenton RA, Vargas SL et al. Localization of the succinate receptor in the distal nephron and its signaling in polarized MDCK cells. Kidney Int 2009; 76: 1258-1267.
-
(2009)
Kidney Int
, vol.76
, pp. 1258-1267
-
-
Robben, J.H.1
Fenton, R.A.2
Vargas, S.L.3
-
40
-
-
0033404955
-
Elements of a paracrine tubular renin angiotensin system along the entire nephron
-
Rohrwasser A, Morgan T, Dillon HF et al. Elements of a paracrine tubular renin angiotensin system along the entire nephron. Hypertension 1999; 34: 1265-1274.
-
(1999)
Hypertension
, vol.34
, pp. 1265-1274
-
-
Rohrwasser, A.1
Morgan, T.2
Dillon, H.F.3
-
41
-
-
62549119072
-
Collecting duct renin: A major player in angiotensin II-dependent hypertension
-
Prieto-Carrasquero MC, Botros FT, Kobori H et al. Collecting duct renin: a major player in angiotensin II-dependent hypertension. J Am Soc Hypertens 2009; 3: 96-104.
-
(2009)
J Am Soc Hypertens
, vol.3
, pp. 96-104
-
-
Prieto-Carrasquero, M.C.1
Botros, F.T.2
Kobori, H.3
-
42
-
-
45849143635
-
The collecting duct is the major source of prorenin in diabetes
-
Kang JJ, Toma I, Sipos A et al. The collecting duct is the major source of prorenin in diabetes. Hypertension 2008; 51: 1597-1604.
-
(2008)
Hypertension
, vol.51
, pp. 1597-1604
-
-
Kang, J.J.1
Toma, I.2
Sipos, A.3
-
43
-
-
33746637130
-
Quantitative imaging of basic functions in renal (patho)physiology
-
Kang JJ, Toma I, Sipos A et al. Quantitative imaging of basic functions in renal (patho)physiology. Am J Physiol Renal Physiol 2006; 291: F495-F502.
-
(2006)
Am J Physiol Renal Physiol
, vol.291
-
-
Kang, J.J.1
Toma, I.2
Sipos, A.3
-
45
-
-
35848961934
-
Advances in renal (patho)physiology using multi-photon microscopy
-
Sipos A, Toma I, Kang JJ et al. Advances in renal (patho)physiology using multi-photon microscopy. Kidney Int 2007; 72: 1188-1191.
-
(2007)
Kidney Int
, vol.72
, pp. 1188-1191
-
-
Sipos, A.1
Toma, I.2
Kang, J.J.3
-
47
-
-
33747050068
-
Increased cyclooxygenase-2, hyperfiltration, glomerulosclerosis, and diabetic nephropathy: Put the blame on the (pro) renin receptor?
-
Nguyen G. Increased cyclooxygenase-2, hyperfiltration, glomerulosclerosis, and diabetic nephropathy: put the blame on the (pro)renin receptor? Kidney Int 2006; 70: 618-620.
-
(2006)
Kidney Int
, vol.70
, pp. 618-620
-
-
Nguyen, G.1
-
48
-
-
0033572643
-
Organization and sequence of the gene for the human mitochondrial dicarboxylate carrier: Evolution of the carrier family
-
Fiermonte G, Dolce V, Arrigoni R et al. Organization and sequence of the gene for the human mitochondrial dicarboxylate carrier: evolution of the carrier family. Biochem J 1999; 344: 953-960.
-
(1999)
Biochem J
, vol.344
, pp. 953-960
-
-
Fiermonte, G.1
Dolce, V.2
Arrigoni, R.3
-
49
-
-
1242317685
-
The SLC13 gene family of sodium sulphate/ carboxylate cotransporters
-
Markovich D, Murer H. The SLC13 gene family of sodium sulphate/ carboxylate cotransporters. Pflugers Arch 2004; 447: 594-602.
-
(2004)
Pflugers Arch
, vol.447
, pp. 594-602
-
-
Markovich, D.1
Murer, H.2
|