The orphan G protein-coupled receptor GPR40 is activated by medium and long chain fatty acids

Journal of Biological Chemistry

Volumn 278, Issue 13, 2003, Pages 11303-11311

  Briscoe, Celia P ^a,b   Tadayyon, Mohammad ^b,c   Andrews, John L ^a   Benson, William G ^a   Chambers, Jon K ^b   Eilert, Michelle M ^a   Ellis, Catherine ^a   Elshourbagy, Nabil A ^b   Goetz, Aaron S ^a   Minnick, Dana T ^a   Murdock, Paul R ^b   Sauls Jr , Howard R ^a   Shabon, Usman ^b   Spinage, Lisa D ^b,d   Strum, Jay C ^a   Szekeres, Philip G ^b   Tan, Kong B ^a   Way, James M ^a   Ignar, Diane M ^a   Wilson, Shelagh ^b   Muir, Alison I ^b   more..

^a GLAXOSMITHKLINE   (United States)

^b GLAXOSMITHKLINE   (United Kingdom)

^c BOEHRINGER INGELHEIM PHARMA GMBH AND CO KG   (Germany)

^d Upstate Ltd   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

BRAIN; CELLS; FATTY ACIDS; PROTEINS;

PROTEIN-COUPLED RECEPTORS;

BIOCHEMISTRY;

5,8,11 ICOSATRIENOIC ACID; CALCIUM ION; CARBON; CARBOXYLIC ACID; G PROTEIN COUPLED RECEPTOR; GUANINE NUCLEOTIDE BINDING PROTEIN; INSULIN; LIGAND; LONG CHAIN FATTY ACID; LUCIFERASE; MEDIUM CHAIN FATTY ACID; PERTUSSIS TOXIN; PROTEIN GPR40; UNCLASSIFIED DRUG; CALCIUM; CELL SURFACE RECEPTOR; FATTY ACID; FFAR1 PROTEIN, HUMAN; GPR40 PROTEIN, MOUSE; PRIMER DNA;

ANIMAL CELL; ARTICLE; BRAIN; CELL CULTURE; CELL LINE; CHO CELL; CONTROLLED STUDY; CULTURE MEDIUM; ENZYME ACTIVITY; ENZYME INDUCTION; ENZYME INHIBITION; FLUOROMETRY; HUMAN; HUMAN CELL; NONHUMAN; NUCLEOTIDE SEQUENCE; PANCREAS ISLET BETA CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; ANIMAL; DRUG EFFECT; GENETICS; HAMSTER; IN SITU HYBRIDIZATION; METABOLISM; MOLECULAR CLONING; MOLECULAR GENETICS;

ANIMALIA; CRICETINAE; CRICETULUS GRISEUS; RODENTIA;

ANIMALS; BASE SEQUENCE; CALCIUM; CELL LINE; CLONING, MOLECULAR; CRICETINAE; DNA PRIMERS; FATTY ACIDS; HUMANS; IN SITU HYBRIDIZATION; LUCIFERASES; MOLECULAR SEQUENCE DATA; RECEPTORS, CELL SURFACE; RECEPTORS, G-PROTEIN-COUPLED;

EID: 0037838892     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M211495200     Document Type: Article

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