Aromatic D-amino acids act as chemoattractant factors for human leukocytes through a G protein-coupled receptor, GPR109B

Proceedings of the National Academy of Sciences of the United States of America

Volumn 106, Issue 10, 2009, Pages 3930-3934

  Irukayama Tomobe, Yoko ^a,b   Tanaka, Hirokazu ^a   Yokomizo, Takehiko ^c,d   Hashidate Yoshida, Tomomi ^d   Yanagisawa, Masashi ^a,e   Sakurai, Takeshi ^a,b,f  

^a JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

^b UNIVERSITY OF TSUKUBA   (Japan)

^c UNIVERSITY OF TOKYO   (Japan)

^d UNIVERSITY OF TOKYO   (Japan)

^e UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^f KANAZAWA UNIVERSITY   (Japan)

Author keywords

D kynurenine; D phenylalanine; D tryptophan; Nicotinic acid (niacin); Orphan receptor

Indexed keywords

ADENYLATE CYCLASE; CALCIUM ION; DEXTRO AMINO ACID; DEXTRO PHENYLALANINE; G PROTEIN COUPLED RECEPTOR; GPR109B PROTEIN; KYNURENINE; NICOTINIC ACID; PERTUSSIS TOXIN; TRYPTOPHAN; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CALCIUM CELL LEVEL; CONTROLLED STUDY; CYCLIC AMP RESPONSIVE ELEMENT; ENZYME ACTIVITY; GENE EXPRESSION; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; LEUKEMIA CELL LINE; MOLECULAR CLONING; NEUTROPHIL CHEMOTAXIS; NONHUMAN; PRIORITY JOURNAL; RECEPTOR AFFINITY; RECEPTOR UPREGULATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA INTERFERENCE; SIGNAL TRANSDUCTION;

AMINO ACIDS, AROMATIC; ANIMALS; CALCIUM; CHEMOTACTIC FACTORS; CHO CELLS; CRICETINAE; CRICETULUS; CYTOPLASM; GENE EXPRESSION REGULATION; GTP-BINDING PROTEINS; HUMANS; NEUTROPHILS; PERTUSSIS TOXIN; RECEPTORS, G-PROTEIN-COUPLED; RECEPTORS, NICOTINIC; RNA, MESSENGER;

EID: 62649093908     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.0811844106     Document Type: Article

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