-
1
-
-
77957055780
-
Integrated methods for the construction of three-dimensional models and computational probing of structure-function relations in G protein coupled receptors
-
Ballesteros JA and Weinstein H (1995) Integrated methods for the construction of three-dimensional models and computational probing of structure-function relations in G protein coupled receptors. Methods Neurosci 25:366-428.
-
(1995)
Methods Neurosci
, vol.25
, pp. 366-428
-
-
Ballesteros, J.A.1
Weinstein, H.2
-
2
-
-
34548170247
-
Regulation of the gene encoding GPR40, a fatty acid receptor expressed selectively in pancreatic β cells
-
Bartoov-Shifman R, Ridner G, Bahar K, Rubins N, and Walker MD (2007) Regulation of the gene encoding GPR40, a fatty acid receptor expressed selectively in pancreatic β cells. J Biol Chem 282:23561- 23571.
-
(2007)
J Biol Chem
, vol.282
, pp. 23561-23571
-
-
Bartoov-Shifman, R.1
Ridner, G.2
Bahar, K.3
Rubins, N.4
Walker, M.D.5
-
3
-
-
0036017173
-
Neutrophilic infiltration in alcoholic hepatitis
-
Bautista AP (2002) Neutrophilic infiltration in alcoholic hepatitis. Alcohol 27:17-21.
-
(2002)
Alcohol
, vol.27
, pp. 17-21
-
-
Bautista, A.P.1
-
4
-
-
6944221886
-
Stimulatory short-term effects of free fatty acids on glucagon secretion at low to normal glucose concentrations
-
Bollheimer LC, Landauer HC, Troll S, Schweimer J, Wrede CE, Schölmerich J, and Buettner R (2004) Stimulatory short-term effects of free fatty acids on glucagon secretion at low to normal glucose concentrations. Metabolism 53:1443-1448.
-
(2004)
Metabolism
, vol.53
, pp. 1443-1448
-
-
Bollheimer, L.C.1
Landauer, H.C.2
Troll, S.3
Schweimer, J.4
Wrede, C.E.5
Schölmerich, J.6
Buettner, R.7
-
5
-
-
0031008135
-
Molecular cloning and tissue expression of a novel orphan G protein-coupled receptor from rat lung
-
Bonini JA, Anderson SM, and Steiner DF (1997) Molecular cloning and tissue expression of a novel orphan G protein-coupled receptor from rat lung. Biochem Biophys Res Commun 234:190-193.
-
(1997)
Biochem Biophys Res Commun
, vol.234
, pp. 190-193
-
-
Bonini, J.A.1
Anderson, S.M.2
Steiner, D.F.3
-
6
-
-
0037838892
-
The orphan G protein-coupled receptor GPR40 is activated by medium and long chain fatty acids
-
Briscoe CP, Tadayyon M, Andrews JL, Benson WG, Chambers JK, Eilert MM, Ellis C, Elshourbagy NA, Goetz AS, Minnick DT, et al. (2003) The orphan G protein-coupled receptor GPR40 is activated by medium and long chain fatty acids. J Biol Chem 278:11303-11311.
-
(2003)
J Biol Chem
, vol.278
, pp. 11303-11311
-
-
Briscoe, C.P.1
Tadayyon, M.2
Andrews, J.L.3
Benson, W.G.4
Chambers, J.K.5
Eilert, M.M.6
Ellis, C.7
Elshourbagy, N.A.8
Goetz, A.S.9
Minnick, D.T.10
-
7
-
-
33745607930
-
Pharmacological regulation of insulin secretion in MIN6 cells through the fatty acid receptor GPR40: Identification of agonist and antagonist small molecules
-
Briscoe CP, Peat AJ, McKeown SC, Corbett DF, Goetz AS, Littleton TR, McCoy DC, Kenakin TP, Andrews JL, Ammala C, et al. (2006) Pharmacological regulation of insulin secretion in MIN6 cells through the fatty acid receptor GPR40: identification of agonist and antagonist small molecules. Br J Pharmacol 148:619-628.
-
(2006)
Br J Pharmacol
, vol.148
, pp. 619-628
-
-
Briscoe, C.P.1
Peat, A.J.2
McKeown, S.C.3
Corbett, D.F.4
Goetz, A.S.5
Littleton, T.R.6
McCoy, D.C.7
Kenakin, T.P.8
Andrews, J.L.9
Ammala, C.10
-
8
-
-
0038363378
-
The orphan G protein-coupled receptors GPR41 and GPR43 are activated by propionate and other short chain carboxylic acids
-
Brown AJ, Goldsworthy SM, Barnes AA, Eilert MM, Tcheang L, Daniels D, Muir AI, Wigglesworth MJ, Kinghorn I, Fraser NJ, et al. (2003) The orphan G protein-coupled receptors GPR41 and GPR43 are activated by propionate and other short chain carboxylic acids. J Biol Chem 278:11312-11319.
-
(2003)
J Biol Chem
, vol.278
, pp. 11312-11319
-
-
Brown, A.J.1
Goldsworthy, S.M.2
Barnes, A.A.3
Eilert, M.M.4
Tcheang, L.5
Daniels, D.6
Muir, A.I.7
Wigglesworth, M.J.8
Kinghorn, I.9
Fraser, N.J.10
-
10
-
-
0038107464
-
Differential effects of short-chain fatty acids on proliferation and production of pro- and anti-inflammatory cytokines by cultured lymphocytes
-
Cavaglieri CR, Nishiyama A, Fernandes LC, Curi R, Miles EA, and Calder PC (2003) Differential effects of short-chain fatty acids on proliferation and production of pro- and anti-inflammatory cytokines by cultured lymphocytes. Life Sci 73:1683-1690.
-
(2003)
Life Sci
, vol.73
, pp. 1683-1690
-
-
Cavaglieri, C.R.1
Nishiyama, A.2
Fernandes, L.C.3
Curi, R.4
Miles, E.A.5
Calder, P.C.6
-
11
-
-
0027400098
-
A rationale for dietary intervention in postmenopausal breast cancer patients: An update
-
Cohen LA, Rose DP, and Wynder EL (1993) A rationale for dietary intervention in postmenopausal breast cancer patients: an update. Nutr Cancer 19:1-10.
-
(1993)
Nutr Cancer
, vol.19
, pp. 1-10
-
-
Cohen, L.A.1
Rose, D.P.2
Wynder, E.L.3
-
12
-
-
0034776770
-
Selective deletion of leptin receptor in neurons leads to obesity
-
Cohen P, Zhao C, Cai X, Montez JM, Rohani SC, Feinstein P, Mombaerts P, and Friedman JM (2001) Selective deletion of leptin receptor in neurons leads to obesity. J Clin Invest 108:1113-1121.
-
(2001)
J Clin Invest
, vol.108
, pp. 1113-1121
-
-
Cohen, P.1
Zhao, C.2
Cai, X.3
Montez, J.M.4
Rohani, S.C.5
Feinstein, P.6
Mombaerts, P.7
Friedman, J.M.8
-
13
-
-
47749128507
-
Seven transmembrane-spanning receptors for free fatty acids as therapeutic targets for diabetes mellitus: Pharmacological, phylogenetic, and drug discovery aspects
-
Costanzi S, Neumann S, and Gershengorn MC (2008) Seven transmembrane-spanning receptors for free fatty acids as therapeutic targets for diabetes mellitus: pharmacological, phylogenetic, and drug discovery aspects. J Biol Chem 283:16269-16273.
-
(2008)
J Biol Chem
, vol.283
, pp. 16269-16273
-
-
Costanzi, S.1
Neumann, S.2
Gershengorn, M.C.3
-
14
-
-
0023276469
-
Short chain fatty acids in human large intestine, portal, hepatic and venous blood
-
Cummings JH, Pomare EW, Branch WJ, Naylor CP, and Macfarlane GT (1987) Short chain fatty acids in human large intestine, portal, hepatic and venous blood. Gut 28:1221-1227.
-
(1987)
Gut
, vol.28
, pp. 1221-1227
-
-
Cummings, J.H.1
Pomare, E.W.2
Branch, W.J.3
Naylor, C.P.4
Macfarlane, G.T.5
-
15
-
-
33845663225
-
The relationship between the effects of short-chain fatty acids on intestinal motility in vitro and GPR43 receptor activation
-
Dass NB, John AK, Bassil AK, Crumbley CW, Shehee WR, Maurio FP, Moore GB, Taylor CM, and Sanger GJ (2007) The relationship between the effects of short-chain fatty acids on intestinal motility in vitro and GPR43 receptor activation. Neurogastroenterol Motil 19:66-74.
-
(2007)
Neurogastroenterol Motil
, vol.19
, pp. 66-74
-
-
Dass, N.B.1
John, A.K.2
Bassil, A.K.3
Crumbley, C.W.4
Shehee, W.R.5
Maurio, F.P.6
Moore, G.B.7
Taylor, C.M.8
Sanger, G.J.9
-
16
-
-
0030938616
-
Insulin resistance: A multifaceted syndrome responsible for NIDDM, obesity, hypertension, dyslipidaemia and atherosclerosis
-
DeFronzo RA (1997) Insulin resistance: a multifaceted syndrome responsible for NIDDM, obesity, hypertension, dyslipidaemia and atherosclerosis. Neth J Med 50:191-197.
-
(1997)
Neth J Med
, vol.50
, pp. 191-197
-
-
DeFronzo, R.A.1
-
17
-
-
52749098923
-
Gpr40 is expressed in enteroendocrine cells and mediates free fatty acid stimulation of incretin secretion
-
Edfalk S, Steneberg P, and Edlund H (2008) Gpr40 is expressed in enteroendocrine cells and mediates free fatty acid stimulation of incretin secretion. Diabetes 57:2280-2287.
-
(2008)
Diabetes
, vol.57
, pp. 2280-2287
-
-
Edfalk, S.1
Steneberg, P.2
Edlund, H.3
-
18
-
-
0042922453
-
Saturated fatty acids synergize with elevated glucose to cause pancreatic β-cell death
-
El-Assaad W, Buteau J, Peyot ML, Nolan C, Roduit R, Hardy S, Joly E, Dbaibo G, Rosenberg L, and Prentki M (2003) Saturated fatty acids synergize with elevated glucose to cause pancreatic β-cell death. Endocrinology 144:4154-4163.
-
(2003)
Endocrinology
, vol.144
, pp. 4154-4163
-
-
El-Assaad, W.1
Buteau, J.2
Peyot, M.L.3
Nolan, C.4
Roduit, R.5
Hardy, S.6
Joly, E.7
Dbaibo, G.8
Rosenberg, L.9
Prentki, M.10
-
20
-
-
20444497357
-
Receptor-independent actions of PPAR thiazolidinedione agonists: Is mitochondrial function the key?
-
Feinstein DL, Spagnolo A, Akar C, Weinberg G, Murphy P, Gavrilyuk V, and Dello Russo C (2005) Receptor-independent actions of PPAR thiazolidinedione agonists: is mitochondrial function the key? Biochem Pharmacol 70:177-188.
-
(2005)
Biochem Pharmacol
, vol.70
, pp. 177-188
-
-
Feinstein, D.L.1
Spagnolo, A.2
Akar, C.3
Weinberg, G.4
Murphy, P.5
Gavrilyuk, V.6
Dello Russo, C.7
-
21
-
-
0042266320
-
Propionic acidemia: A neuropathology case report and review of prior cases
-
Feliz B, Witt DR, and Harris BT (2003) Propionic acidemia: a neuropathology case report and review of prior cases. Arch Pathol Lab Med 127:e325-e328.
-
(2003)
Arch Pathol Lab Med
, vol.127
-
-
Feliz, B.1
Witt, D.R.2
Harris, B.T.3
-
23
-
-
0031781603
-
Inflammatory bowel disease: Etiology and pathogenesis
-
Fiocchi C (1998) Inflammatory bowel disease: etiology and pathogenesis. Gastroenterology 115:182-205.
-
(1998)
Gastroenterology
, vol.115
, pp. 182-205
-
-
Fiocchi, C.1
-
24
-
-
33846327180
-
GPR40 is expressed in glucagon producing cells and affects glucagon secretion
-
Flodgren E, Olde B, Meidute-Abaraviciene S, Winzell MS, Ahrén B, and Salehi A (2007) GPR40 is expressed in glucagon producing cells and affects glucagon secretion. Biochem Biophys Res Commun 354:240-245.
-
(2007)
Biochem Biophys Res Commun
, vol.354
, pp. 240-245
-
-
Flodgren, E.1
Olde, B.2
Meidute-Abaraviciene, S.3
Winzell, M.S.4
Ahrén, B.5
Salehi, A.6
-
26
-
-
33144463383
-
Synthesis and activity of small molecule GPR40 agonists
-
Garrido DM, Corbett DF, Dwornik KA, Goetz AS, Littleton TR, McKeown SC, Mills WY, Smalley TL Jr, Briscoe CP, and Peat AJ (2006) Synthesis and activity of small molecule GPR40 agonists. Bioorg Med Chem Lett 16:1840-1845.
-
(2006)
Bioorg Med Chem Lett
, vol.16
, pp. 1840-1845
-
-
Garrido, D.M.1
Corbett, D.F.2
Dwornik, K.A.3
Goetz, A.S.4
Littleton, T.R.5
McKeown, S.C.6
Mills, W.Y.7
Smalley Jr, T.L.8
Briscoe, C.P.9
Peat, A.J.10
-
27
-
-
50449087891
-
Activation of GPR43 in adipocytes leads to inhibition of lipolysis and suppression of plasma free fatty acids
-
Ge H, Li X, Weiszmann J, Wang P, Baribault H, Chen JL, Tian H, and Li Y (2008) Activation of GPR43 in adipocytes leads to inhibition of lipolysis and suppression of plasma free fatty acids. Endocrinology 149:4519-4526.
-
(2008)
Endocrinology
, vol.149
, pp. 4519-4526
-
-
Ge, H.1
Li, X.2
Weiszmann, J.3
Wang, P.4
Baribault, H.5
Chen, J.L.6
Tian, H.7
Li, Y.8
-
28
-
-
19944434042
-
Studies of relationships between variation of the human G protein-coupled receptor 40 gene and type 2 diabetes and insulin release
-
Hamid YH, Vissing H, Holst B, Urhammer SA, Pyke C, Hansen SK, Glümer C, Borch-Johnsen K, Jørgensen T, Schwartz TW, et al. (2005) Studies of relationships between variation of the human G protein-coupled receptor 40 gene and type 2 diabetes and insulin release. Diabet Med 22:74-80.
-
(2005)
Diabet Med
, vol.22
, pp. 74-80
-
-
Hamid, Y.H.1
Vissing, H.2
Holst, B.3
Urhammer, S.A.4
Pyke, C.5
Hansen, S.K.6
Glümer, C.7
Borch-Johnsen, K.8
Jørgensen, T.9
Schwartz, T.W.10
-
29
-
-
0041355315
-
Saturated fatty acid-induced apoptosis in MDA-MB-231 breast cancer cells: A role for cardiolipin
-
Hardy S, El-Assaad W, Przybytkowski E, Joly E, Prentki M, and Langelier Y (2003) Saturated fatty acid-induced apoptosis in MDA-MB-231 breast cancer cells: a role for cardiolipin. J Biol Chem 278:31861-31870.
-
(2003)
J Biol Chem
, vol.278
, pp. 31861-31870
-
-
Hardy, S.1
El-Assaad, W.2
Przybytkowski, E.3
Joly, E.4
Prentki, M.5
Langelier, Y.6
-
30
-
-
0033692758
-
Oleate activates phosphatidylinositol 3-kinase and promotes proliferation and reduces apoptosis of MDA-MB-231 breast cancer cells, whereas palmitate has opposite effects
-
Hardy S, Langelier Y, and Prentki M (2000) Oleate activates phosphatidylinositol 3-kinase and promotes proliferation and reduces apoptosis of MDA-MB-231 breast cancer cells, whereas palmitate has opposite effects. Cancer Res 60:6353-6358.
-
(2000)
Cancer Res
, vol.60
, pp. 6353-6358
-
-
Hardy, S.1
Langelier, Y.2
Prentki, M.3
-
31
-
-
17144421545
-
Oleate promotes the proliferation of breast cancer cells via the G protein-coupled receptor GPR40
-
Hardy S, St-Onge GG, Joly E, Langelier Y, and Prentki M (2005) Oleate promotes the proliferation of breast cancer cells via the G protein-coupled receptor GPR40. J Biol Chem 280:13285-13291.
-
(2005)
J Biol Chem
, vol.280
, pp. 13285-13291
-
-
Hardy, S.1
St-Onge, G.G.2
Joly, E.3
Langelier, Y.4
Prentki, M.5
-
32
-
-
13444263540
-
Free fatty acids regulate gut incretin glucagon-like peptide-1 secretion through GPR120
-
Hirasawa A, Tsumaya K, Awaji T, Katsuma S, Adachi T, Yamada M, Sugimoto Y, Miyazaki S, and Tsujimoto G (2005) Free fatty acids regulate gut incretin glucagon-like peptide-1 secretion through GPR120. Nat Med 11:90-94.
-
(2005)
Nat Med
, vol.11
, pp. 90-94
-
-
Hirasawa, A.1
Tsumaya, K.2
Awaji, T.3
Katsuma, S.4
Adachi, T.5
Yamada, M.6
Sugimoto, Y.7
Miyazaki, S.8
Tsujimoto, G.9
-
33
-
-
24344458875
-
The short-term effect of fatty acids on glucagon secretion is influenced by their chain length, spatial configuration, and degree of unsaturation: Studies in vitro
-
Hong J, Abudula R, Chen J, Jeppesen PB, Dyrskog SE, Xiao J, Colombo M, and Hermansen K (2005a) The short-term effect of fatty acids on glucagon secretion is influenced by their chain length, spatial configuration, and degree of unsaturation: studies in vitro. Metabolism 54:1329-1336.
-
(2005)
Metabolism
, vol.54
, pp. 1329-1336
-
-
Hong, J.1
Abudula, R.2
Chen, J.3
Jeppesen, P.B.4
Dyrskog, S.E.5
Xiao, J.6
Colombo, M.7
Hermansen, K.8
-
34
-
-
27844440904
-
Acetate and propionate short chain fatty acids stimulate adipogenesis via GPCR43
-
Hong YH, Nishimura Y, Hishikawa D, Tsuzuki H, Miyahara H, Gotoh C, Choi KC, Feng DD, Chen C, Lee HG, et al. (2005b) Acetate and propionate short chain fatty acids stimulate adipogenesis via GPCR43. Endocrinology 146:5092-5099.
-
(2005)
Endocrinology
, vol.146
, pp. 5092-5099
-
-
Hong, Y.H.1
Nishimura, Y.2
Hishikawa, D.3
Tsuzuki, H.4
Miyahara, H.5
Gotoh, C.6
Choi, K.C.7
Feng, D.D.8
Chen, C.9
Lee, H.G.10
-
35
-
-
0037434991
-
Free fatty acids regulate insulin secretion from pancreatic β cells through GPR40
-
Itoh Y, Kawamata Y, Harada M, Kobayashi M, Fujii R, Fukusumi S, Ogi K, Hosoya M, Tanaka Y, Uejima H, et al. (2003) Free fatty acids regulate insulin secretion from pancreatic β cells through GPR40. Nature 422:173-176.
-
(2003)
Nature
, vol.422
, pp. 173-176
-
-
Itoh, Y.1
Kawamata, Y.2
Harada, M.3
Kobayashi, M.4
Fujii, R.5
Fukusumi, S.6
Ogi, K.7
Hosoya, M.8
Tanaka, Y.9
Uejima, H.10
-
36
-
-
33646376658
-
Short-chain fatty acid receptor, GPR43, is expressed by enteroendocrine cells and mucosal mast cells in rat intestine
-
Karaki S, Mitsui R, Hayashi H, Kato I, Sugiya H, Iwanaga T, Furness JB, and Kuwahara A (2006) Short-chain fatty acid receptor, GPR43, is expressed by enteroendocrine cells and mucosal mast cells in rat intestine. Cell Tissue Res 324:353-360.
-
(2006)
Cell Tissue Res
, vol.324
, pp. 353-360
-
-
Karaki, S.1
Mitsui, R.2
Hayashi, H.3
Kato, I.4
Sugiya, H.5
Iwanaga, T.6
Furness, J.B.7
Kuwahara, A.8
-
37
-
-
52249093427
-
The fatty acid receptor GPR40 plays a role in insulin secretion in vivo after high-fat feeding
-
Kebede M, Alquier T, Latour MG, Semache M, Tremblay C, and Poitout V (2008) The fatty acid receptor GPR40 plays a role in insulin secretion in vivo after high-fat feeding. Diabetes 57:2432-2437.
-
(2008)
Diabetes
, vol.57
, pp. 2432-2437
-
-
Kebede, M.1
Alquier, T.2
Latour, M.G.3
Semache, M.4
Tremblay, C.5
Poitout, V.6
-
38
-
-
0037423719
-
A human cell surface receptor activated by free fatty acids and thiazolidinedione drugs
-
Kotarsky K, Nilsson NE, Flodgren E, Owman C, and Olde B (2003) A human cell surface receptor activated by free fatty acids and thiazolidinedione drugs. Biochem Biophys Res Commun 301:406-410.
-
(2003)
Biochem Biophys Res Commun
, vol.301
, pp. 406-410
-
-
Kotarsky, K.1
Nilsson, N.E.2
Flodgren, E.3
Owman, C.4
Olde, B.5
-
39
-
-
0018628021
-
Rapid diagnosis of anaerobic infections by gas-liquid chromatography
-
Ladas S, Arapakis G, Malamou-Ladas H, Palikaris G, and Arseni A (1979) Rapid diagnosis of anaerobic infections by gas-liquid chromatography. J Clin Pathol 32:1163-1167.
-
(1979)
J Clin Pathol
, vol.32
, pp. 1163-1167
-
-
Ladas, S.1
Arapakis, G.2
Malamou-Ladas, H.3
Palikaris, G.4
Arseni, A.5
-
40
-
-
58149100292
-
Lack of FFAR1/GPR40 does not protect mice from high-fat diet-induced metabolic disease
-
Lan H, Hoos LM, Liu L, Tetzloff G, Hu W, Abbondanzo SJ, Vassileva G, Gustafson EL, Hedrick JA, and Davis HR (2008) Lack of FFAR1/GPR40 does not protect mice from high-fat diet-induced metabolic disease. Diabetes 57:2999-3006.
-
(2008)
Diabetes
, vol.57
, pp. 2999-3006
-
-
Lan, H.1
Hoos, L.M.2
Liu, L.3
Tetzloff, G.4
Hu, W.5
Abbondanzo, S.J.6
Vassileva, G.7
Gustafson, E.L.8
Hedrick, J.A.9
Davis, H.R.10
-
41
-
-
34047177401
-
GPR40 is necessary but not sufficient for fatty acid stimulation of insulin secretion in vivo
-
Latour MG, Alquier T, Oseid E, Tremblay C, Jetton TL, Luo J, Lin DC, and Poitout V (2007) GPR40 is necessary but not sufficient for fatty acid stimulation of insulin secretion in vivo. Diabetes 56:1087-1094.
-
(2007)
Diabetes
, vol.56
, pp. 1087-1094
-
-
Latour, M.G.1
Alquier, T.2
Oseid, E.3
Tremblay, C.4
Jetton, T.L.5
Luo, J.6
Lin, D.C.7
Poitout, V.8
-
42
-
-
0038491435
-
Functional characterization of human receptors for short chain fatty acids and their role in polymorphonuclear cell activation
-
Le Poul E, Loison C, Struyf S, Springael JY, Lannoy V, Decobecq ME, Brezillon S, Dupriez V, Vassart G, Van Damme J, et al. (2003) Functional characterization of human receptors for short chain fatty acids and their role in polymorphonuclear cell activation. J Biol Chem 278:25481-25489.
-
(2003)
J Biol Chem
, vol.278
, pp. 25481-25489
-
-
Le Poul, E.1
Loison, C.2
Struyf, S.3
Springael, J.Y.4
Lannoy, V.5
Decobecq, M.E.6
Brezillon, S.7
Dupriez, V.8
Vassart, G.9
Van Damme, J.10
-
43
-
-
57349142454
-
Identification and functional characterization of allosteric agonists for the G protein-coupled receptor FFA2
-
Lee T, Schwandner R, Swaminath G, Weiszmann J, Cardozo M, Greenberg J, Jaeckel P, Ge H, Wang Y, Jiao X, et al. (2008) Identification and functional characterization of allosteric agonists for the G protein-coupled receptor FFA2. Mol Pharmacol 74:1599-1609.
-
(2008)
Mol Pharmacol
, vol.74
, pp. 1599-1609
-
-
Lee, T.1
Schwandner, R.2
Swaminath, G.3
Weiszmann, J.4
Cardozo, M.5
Greenberg, J.6
Jaeckel, P.7
Ge, H.8
Wang, Y.9
Jiao, X.10
-
44
-
-
0027947379
-
β-Cell lipotoxicity in the pathogenesis of non-insulin-dependent diabetes mellitus of obese rats: Impairment in adipocyte-β-cell relationships
-
Lee Y, Hirose H, Ohneda M, Johnson JH, McGarry JD, and Unger RH (1994) β-Cell lipotoxicity in the pathogenesis of non-insulin-dependent diabetes mellitus of obese rats: impairment in adipocyte-β-cell relationships. Proc Natl Acad Sci U S A 91:10878-10882.
-
(1994)
Proc Natl Acad Sci U S A
, vol.91
, pp. 10878-10882
-
-
Lee, Y.1
Hirose, H.2
Ohneda, M.3
Johnson, J.H.4
McGarry, J.D.5
Unger, R.H.6
-
45
-
-
58149102765
-
-
Leonard JN, Chu ZL, Bruce MA, and Boatman PD (2006) inventors; Arena Pharma Inc, Leonard JN, Chu ZL, Bruce MA, and Boatman PD, assignees. GPR41 and modulators thereof for the treatment of insulin-related disorders. World Patent no. WO2006052566. 2006 May 18
-
Leonard JN, Chu ZL, Bruce MA, and Boatman PD (2006) inventors; Arena Pharma Inc., Leonard JN, Chu ZL, Bruce MA, and Boatman PD, assignees. GPR41 and modulators thereof for the treatment of insulin-related disorders. World Patent no. WO2006052566. 2006 May 18.
-
-
-
-
46
-
-
58149085192
-
-
Leonard JN and Hakak Y (2005) inventors; Arena Pharma Inc, Leonard JN, Hakek Y, assignees. GPR43 and modulators thereof for the treatment of metabolic-related disorders. World Patent WO2006036688. 6 Apr 2006
-
Leonard JN and Hakak Y (2005) inventors; Arena Pharma Inc., Leonard JN, Hakek Y, assignees. GPR43 and modulators thereof for the treatment of metabolic-related disorders. World Patent WO2006036688. 6 Apr 2006.
-
-
-
-
47
-
-
34547590401
-
Expression of free fatty acid receptor GPR40 in the central nervous system of adult monkeys
-
Ma D, Tao B, Warashina S, Kotani S, Lu L, Kaplamadzhiev DB, Mori Y, Tonchev AB, and Yamashima T (2007) Expression of free fatty acid receptor GPR40 in the central nervous system of adult monkeys. Neurosci Res 58:394-401.
-
(2007)
Neurosci Res
, vol.58
, pp. 394-401
-
-
Ma, D.1
Tao, B.2
Warashina, S.3
Kotani, S.4
Lu, L.5
Kaplamadzhiev, D.B.6
Mori, Y.7
Tonchev, A.B.8
Yamashima, T.9
-
48
-
-
40849126885
-
Expression of free fatty acid receptor GPR40 in the neurogenic niche of adult monkey hippocampus
-
Ma D, Lu L, Boneva NB, Warashina S, Kaplamadzhiev DB, Mori Y, Nakaya MA, Kikuchi M, Tonchev AB, Okano H, et al. (2008) Expression of free fatty acid receptor GPR40 in the neurogenic niche of adult monkey hippocampus. Hippocampus 18:326-333.
-
(2008)
Hippocampus
, vol.18
, pp. 326-333
-
-
Ma, D.1
Lu, L.2
Boneva, N.B.3
Warashina, S.4
Kaplamadzhiev, D.B.5
Mori, Y.6
Nakaya, M.A.7
Kikuchi, M.8
Tonchev, A.B.9
Okano, H.10
-
49
-
-
48249125013
-
Palmitate-induced β-cell dysfunction is associated with excessive NO production and is reversed by thiazolidinedione-mediated inhibition of GPR40 transduction mechanisms
-
Meidute Abaraviciene S, Lundquist I, Galvanovskis J, Flodgren E, Olde B, and Salehi A (2008) Palmitate-induced β-cell dysfunction is associated with excessive NO production and is reversed by thiazolidinedione-mediated inhibition of GPR40 transduction mechanisms. PLoS ONE 3:e2182.
-
(2008)
PLoS ONE
, vol.3
-
-
Meidute Abaraviciene, S.1
Lundquist, I.2
Galvanovskis, J.3
Flodgren, E.4
Olde, B.5
Salehi, A.6
-
50
-
-
0033021674
-
Chimaeric Gα proteins: Their potential use in drug discovery
-
Milligan G and Rees S (1999) Chimaeric Gα proteins: their potential use in drug discovery. Trends Pharmacol Sci 20:118-124.
-
(1999)
Trends Pharmacol Sci
, vol.20
, pp. 118-124
-
-
Milligan, G.1
Rees, S.2
-
51
-
-
30444435782
-
Heterotrimeric G-proteins: A short history
-
Milligan G and Kostenis E (2006) Heterotrimeric G-proteins: a short history. Br J Pharmacol 147 (Suppl 1):S46-S55.
-
(2006)
Br J Pharmacol
, vol.147
, Issue.SUPPL. 1
-
-
Milligan, G.1
Kostenis, E.2
-
52
-
-
33744915759
-
G protein-coupled receptors for free fatty acids
-
Milligan G, Stoddart LA, and Brown AJ (2006) G protein-coupled receptors for free fatty acids. Cell Signal 18:1360-1365.
-
(2006)
Cell Signal
, vol.18
, pp. 1360-1365
-
-
Milligan, G.1
Stoddart, L.A.2
Brown, A.J.3
-
54
-
-
12144286883
-
Identification of granulocyte subtype-selective receptors and ion channels by using a high-density oligonucleotide probe array
-
Nakajima T, Iikura M, Okayama Y, Matsumoto K, Uchiyama C, Shirakawa T, Yang X, Adra CN, Hirai K, and Saito H (2004) Identification of granulocyte subtype-selective receptors and ion channels by using a high-density oligonucleotide probe array. J Allergy Clin Immunol 113:528-535.
-
(2004)
J Allergy Clin Immunol
, vol.113
, pp. 528-535
-
-
Nakajima, T.1
Iikura, M.2
Okayama, Y.3
Matsumoto, K.4
Uchiyama, C.5
Shirakawa, T.6
Yang, X.7
Adra, C.N.8
Hirai, K.9
Saito, H.10
-
55
-
-
0026614980
-
2+ in resting and stimulated human neutrophils by short-chain carboxylic acids at neutral pH
-
2+ in resting and stimulated human neutrophils by short-chain carboxylic acids at neutral pH. Infect Immun 60:5307-5311.
-
(1992)
Infect Immun
, vol.60
, pp. 5307-5311
-
-
Nakao, S.1
Fujii, A.2
Niederman, R.3
-
56
-
-
0037453280
-
Identification of a free fatty acid receptor, FFA2R, expressed on leukocytes and activated by short-chain fatty acids
-
Nilsson NE, Kotarsky K, Owman C, and Olde B (2003) Identification of a free fatty acid receptor, FFA2R, expressed on leukocytes and activated by short-chain fatty acids. Biochem Biophys Res Commun 303:1047-1052.
-
(2003)
Biochem Biophys Res Commun
, vol.303
, pp. 1047-1052
-
-
Nilsson, N.E.1
Kotarsky, K.2
Owman, C.3
Olde, B.4
-
57
-
-
33845517309
-
Fatty acid signaling in the β-cell and insulin secretion
-
Nolan CJ, Madiraju MS, Delghingaro-Augusto V, Peyot ML, and Prentki M (2006) Fatty acid signaling in the β-cell and insulin secretion. Diabetes 55 (Suppl 2): S16-S23.
-
(2006)
Diabetes
, vol.55
, Issue.SUPPL. 2
-
-
Nolan, C.J.1
Madiraju, M.S.2
Delghingaro-Augusto, V.3
Peyot, M.L.4
Prentki, M.5
-
58
-
-
13844266013
-
GPR40 gene Arg211His polymorphism may contribute to the variation of insulin secretory capacity in Japanese men
-
Ogawa T, Hirose H, Miyashita K, Saito I, and Saruta T (2005) GPR40 gene Arg211His polymorphism may contribute to the variation of insulin secretory capacity in Japanese men. Metabolism 54:296-299.
-
(2005)
Metabolism
, vol.54
, pp. 296-299
-
-
Ogawa, T.1
Hirose, H.2
Miyashita, K.3
Saito, I.4
Saruta, T.5
-
59
-
-
7044249536
-
Palmitate stimulation of glucagon secretion in mouse pancreatic alpha-cells results from activation of L-type calcium channels and elevation of cytoplasmic calcium
-
Olofsson CS, Salehi A, Göpel SO, Holm C, and Rorsman P (2004) Palmitate stimulation of glucagon secretion in mouse pancreatic alpha-cells results from activation of L-type calcium channels and elevation of cytoplasmic calcium. Diabetes 53:2836-2843.
-
(2004)
Diabetes
, vol.53
, pp. 2836-2843
-
-
Olofsson, C.S.1
Salehi, A.2
Göpel, S.O.3
Holm, C.4
Rorsman, P.5
-
60
-
-
0029932643
-
New insights into pancreatic β-cell metabolic signaling in insulin secretion
-
Prentki M (1996) New insights into pancreatic β-cell metabolic signaling in insulin secretion. Eur J Endocrinol 134:272-286.
-
(1996)
Eur J Endocrinol
, vol.134
, pp. 272-286
-
-
Prentki, M.1
-
61
-
-
0030029605
-
Are the β-cell signaling molecules malonyl-CoA and cystolic long-chain acyl-CoA implicated in multiple tissue defects of obesity and NIDDM?
-
Prentki M and Corkey BE (1996) Are the β-cell signaling molecules malonyl-CoA and cystolic long-chain acyl-CoA implicated in multiple tissue defects of obesity and NIDDM? Diabetes 45:273-283.
-
(1996)
Diabetes
, vol.45
, pp. 273-283
-
-
Prentki, M.1
Corkey, B.E.2
-
62
-
-
0036896505
-
Malonyl-CoA signaling, lipid partitioning, and glucolipotoxicity: Role in β-cell adaptation and failure in the etiology of diabetes
-
Prentki M, Joly E, El-Assaad W, and Roduit R (2002) Malonyl-CoA signaling, lipid partitioning, and glucolipotoxicity: role in β-cell adaptation and failure in the etiology of diabetes. Diabetes 51 (Suppl 3):S405-S413.
-
(2002)
Diabetes
, vol.51
, Issue.SUPPL. 3
-
-
Prentki, M.1
Joly, E.2
El-Assaad, W.3
Roduit, R.4
-
63
-
-
45249108705
-
Regulation of the GPR40 locus: Towards a molecular understanding
-
Ridner G, Bartoov-Shifman R, Zalogin T, Avnit-Sagi T, Bahar K, Sharivkin R, Kantorovich L, Weiss S, and Walker MD (2008) Regulation of the GPR40 locus: towards a molecular understanding. Biochem Soc Trans 36:360-362.
-
(2008)
Biochem Soc Trans
, vol.36
, pp. 360-362
-
-
Ridner, G.1
Bartoov-Shifman, R.2
Zalogin, T.3
Avnit-Sagi, T.4
Bahar, K.5
Sharivkin, R.6
Kantorovich, L.7
Weiss, S.8
Walker, M.D.9
-
64
-
-
0030692082
-
Effects of dietary fatty acids on breast and prostate cancers: Evidence from in vitro experiments and animal studies
-
Rose DP (1997) Effects of dietary fatty acids on breast and prostate cancers: evidence from in vitro experiments and animal studies. Am J Clin Nutr 66:1513S-1522S.
-
(1997)
Am J Clin Nutr
, vol.66
-
-
Rose, D.P.1
-
65
-
-
0029889988
-
PHD: Predicting one-dimensional protein structure by profile-based neural networks
-
Rost B (1996) PHD: predicting one-dimensional protein structure by profile-based neural networks. Methods Enzymol 266:525-539.
-
(1996)
Methods Enzymol
, vol.266
, pp. 525-539
-
-
Rost, B.1
-
67
-
-
0031581088
-
A cluster of four novel human g protein-coupled receptor genes occurring in close proximity to CD22 gene on chromosome 19q13.1
-
Sawzdargo M, George SR, Nguyen T, Xu S, Kolakowski LF, and O'Dowd BF (1997) A cluster of four novel human g protein-coupled receptor genes occurring in close proximity to CD22 gene on chromosome 19q13.1. Biochem Biophys Res Commun 239:543-547.
-
(1997)
Biochem Biophys Res Commun
, vol.239
, pp. 543-547
-
-
Sawzdargo, M.1
George, S.R.2
Nguyen, T.3
Xu, S.4
Kolakowski, L.F.5
O'Dowd, B.F.6
-
68
-
-
33751520308
-
Free fatty acids increase cytosolic free calcium and stimulate insulin secretion from β-cells through activation of GPR40
-
Schnell S, Schaefer M, and Schöfl C (2007) Free fatty acids increase cytosolic free calcium and stimulate insulin secretion from β-cells through activation of GPR40. Mol Cell Endocrinol 263:173-180.
-
(2007)
Mol Cell Endocrinol
, vol.263
, pp. 173-180
-
-
Schnell, S.1
Schaefer, M.2
Schöfl, C.3
-
69
-
-
0037307761
-
LSSIG is a novel murine leukocyte-specific GPCR that is induced by the activation of STAT3
-
Senga T, Iwamoto S, Yoshida T, Yokota T, Adachi K, Azuma E, Hamaguchi M, and Iwamoto T (2003) LSSIG is a novel murine leukocyte-specific GPCR that is induced by the activation of STAT3. Blood 101:1185-1187.
-
(2003)
Blood
, vol.101
, pp. 1185-1187
-
-
Senga, T.1
Iwamoto, S.2
Yoshida, T.3
Yokota, T.4
Adachi, K.5
Azuma, E.6
Hamaguchi, M.7
Iwamoto, T.8
-
70
-
-
0014148047
-
Physiologic effects of metabolic fuels on carbohydrate metabolism. I. Acute effect of elevation of plasma free fatty acids on hepatic glucose output, peripheral glucose utilization, serum insulin, and plasma glucagon levels
-
Seyffert WA Jr and Madison LL (1967) Physiologic effects of metabolic fuels on carbohydrate metabolism. I. Acute effect of elevation of plasma free fatty acids on hepatic glucose output, peripheral glucose utilization, serum insulin, and plasma glucagon levels. Diabetes 16:765-776.
-
(1967)
Diabetes
, vol.16
, pp. 765-776
-
-
Seyffert Jr, W.A.1
Madison, L.L.2
-
71
-
-
25144433441
-
Role of GPR40 in fatty acid action on the β-cell line INS-1E
-
Shapiro H, Shachar S, Sekler I, Hershfinkel M, and Walker MD (2005) Role of GPR40 in fatty acid action on the β-cell line INS-1E. Biochem Biophys Res Commun 335:97-104.
-
(2005)
Biochem Biophys Res Commun
, vol.335
, pp. 97-104
-
-
Shapiro, H.1
Shachar, S.2
Sekler, I.3
Hershfinkel, M.4
Walker, M.D.5
-
72
-
-
0032716189
-
De novo lipogenesis, lipid kinetics, and whole-body lipid balances in humans after acute alcohol consumption
-
Siler SQ, Neese RA, and Hellerstein MK (1999) De novo lipogenesis, lipid kinetics, and whole-body lipid balances in humans after acute alcohol consumption. Am J Clin Nutr 70:928-936.
-
(1999)
Am J Clin Nutr
, vol.70
, pp. 928-936
-
-
Siler, S.Q.1
Neese, R.A.2
Hellerstein, M.K.3
-
73
-
-
34250879091
-
Synthesis and biological evaluation of 3-aryl-3-(4-phenoxy)-propionic acid as a novel series of G protein-coupled receptor 40 agonists
-
Song F, Lu S, Gunnet J, Xu JZ, Wines P, Proost J, Liang Y, Baumann C, Lenhard J, Murray WV, et al. (2007) Synthesis and biological evaluation of 3-aryl-3-(4-phenoxy)-propionic acid as a novel series of G protein-coupled receptor 40 agonists. J Med Chem 50:2807-2817.
-
(2007)
J Med Chem
, vol.50
, pp. 2807-2817
-
-
Song, F.1
Lu, S.2
Gunnet, J.3
Xu, J.Z.4
Wines, P.5
Proost, J.6
Liang, Y.7
Baumann, C.8
Lenhard, J.9
Murray, W.V.10
-
74
-
-
0029888870
-
Essentiality of circulating fatty acids for glucose-stimulated insulin secretion in the fasted rat
-
Stein DT, Esser V, Stevenson BE, Lane KE, Whiteside JH, Daniels MB, Chen S, and McGarry JD (1996) Essentiality of circulating fatty acids for glucose-stimulated insulin secretion in the fasted rat. J Clin Invest 97:2728-2735.
-
(1996)
J Clin Invest
, vol.97
, pp. 2728-2735
-
-
Stein, D.T.1
Esser, V.2
Stevenson, B.E.3
Lane, K.E.4
Whiteside, J.H.5
Daniels, M.B.6
Chen, S.7
McGarry, J.D.8
-
75
-
-
0030876806
-
The insulinotropic potency of fatty acids is influenced profoundly by their chain length and degree of saturation
-
Stein DT, Stevenson BE, Chester MW, Basit M, Daniels MB, Turley SD, and McGarry JD (1997) The insulinotropic potency of fatty acids is influenced profoundly by their chain length and degree of saturation. J Clin Invest 100:398-403.
-
(1997)
J Clin Invest
, vol.100
, pp. 398-403
-
-
Stein, D.T.1
Stevenson, B.E.2
Chester, M.W.3
Basit, M.4
Daniels, M.B.5
Turley, S.D.6
McGarry, J.D.7
-
76
-
-
20944433543
-
The FFA receptor GPR40 links hyperinsulinemia, hepatic steatosis, and impaired glucose homeostasis in mouse
-
Steneberg P, Rubins N, Bartoov-Shifman R, Walker MD, and Edlund H (2005) The FFA receptor GPR40 links hyperinsulinemia, hepatic steatosis, and impaired glucose homeostasis in mouse. Cell Metab 1:245-258.
-
(2005)
Cell Metab
, vol.1
, pp. 245-258
-
-
Steneberg, P.1
Rubins, N.2
Bartoov-Shifman, R.3
Walker, M.D.4
Edlund, H.5
-
77
-
-
33947358098
-
35S]thio)triphosphate binding studies reflects binding of an endogenous agonist
-
35S]thio)triphosphate binding studies reflects binding of an endogenous agonist. Mol Pharmacol 71:994-1005.
-
(2007)
Mol Pharmacol
, vol.71
, pp. 994-1005
-
-
Stoddart, L.A.1
Brown, A.J.2
Milligan, G.3
-
78
-
-
57749112018
-
-
Stoddart LA, Smith NJ, Jenkins L, Brown AJ, and Milligan G (2008) Conserved polar residues in transmembrane domains V, VI, and VII of free fatty acid receptor 2 and free fatty acid receptor 3 are required for the binding and function of short chain fatty acids. J Biol Chem 283:32913-32924.
-
Stoddart LA, Smith NJ, Jenkins L, Brown AJ, and Milligan G (2008) Conserved polar residues in transmembrane domains V, VI, and VII of free fatty acid receptor 2 and free fatty acid receptor 3 are required for the binding and function of short chain fatty acids. J Biol Chem 283:32913-32924.
-
-
-
-
79
-
-
35748937333
-
Identification of residues important for agonist recognition and activation in GPR40
-
Sum CS, Tikhonova IG, Neumann S, Engel S, Raaka BM, Costanzi S, and Gershengorn MC (2007) Identification of residues important for agonist recognition and activation in GPR40. J Biol Chem 282:29248-29255.
-
(2007)
J Biol Chem
, vol.282
, pp. 29248-29255
-
-
Sum, C.S.1
Tikhonova, I.G.2
Neumann, S.3
Engel, S.4
Raaka, B.M.5
Costanzi, S.6
Gershengorn, M.C.7
-
80
-
-
30144441512
-
A chemogenomic analysis of the transmembrane binding cavity of human g-protein-coupled receptors
-
Surgand JS, Rodrigo J, Kellenberger E, and Rognan D (2006) A chemogenomic analysis of the transmembrane binding cavity of human g-protein-coupled receptors. Proteins 62:509-538.
-
(2006)
Proteins
, vol.62
, pp. 509-538
-
-
Surgand, J.S.1
Rodrigo, J.2
Kellenberger, E.3
Rognan, D.4
-
82
-
-
50949128408
-
Selective small-molecule agonists of G protein-coupled receptor 40 promote glucose-dependent insulin secretion and reduce blood glucose in mice
-
Tan CP, Feng Y, Zhou YP, Eiermann GJ, Petrov A, Zhou C, Lin S, Salituro G, Meinke P, Mosley R, et al. (2008) Selective small-molecule agonists of G protein-coupled receptor 40 promote glucose-dependent insulin secretion and reduce blood glucose in mice. Diabetes 57:2211-2219
-
(2008)
Diabetes
, vol.57
, pp. 2211-2219
-
-
Tan, C.P.1
Feng, Y.2
Zhou, Y.P.3
Eiermann, G.J.4
Petrov, A.5
Zhou, C.6
Lin, S.7
Salituro, G.8
Meinke, P.9
Mosley, R.10
-
83
-
-
39149097541
-
Discovery of novel agonists and antagonists of the free fatty acid receptor 1 (FFAR1) using virtual screening
-
Tikhonova IG, Sum CS, Neumann S, Engel S, Raaka BM, Costanzi S, and Gershengorn MC (2008) Discovery of novel agonists and antagonists of the free fatty acid receptor 1 (FFAR1) using virtual screening. J Med Chem 51:625-633.
-
(2008)
J Med Chem
, vol.51
, pp. 625-633
-
-
Tikhonova, I.G.1
Sum, C.S.2
Neumann, S.3
Engel, S.4
Raaka, B.M.5
Costanzi, S.6
Gershengorn, M.C.7
-
84
-
-
34347220548
-
Bidirectional, iterative approach to the structural delineation of the functional "chemoprint" in GPR40 for agonist recognition
-
Tikhonova IG, Sum CS, Neumann S, Thomas CJ, Raaka BM, Costanzi S, and Gershengorn MC (2007) Bidirectional, iterative approach to the structural delineation of the functional "chemoprint" in GPR40 for agonist recognition. J Med Chem 50:2981-2989.
-
(2007)
J Med Chem
, vol.50
, pp. 2981-2989
-
-
Tikhonova, I.G.1
Sum, C.S.2
Neumann, S.3
Thomas, C.J.4
Raaka, B.M.5
Costanzi, S.6
Gershengorn, M.C.7
-
85
-
-
27844449497
-
GPR40 gene expression in human pancreas and insulinoma
-
Tomita T, Masuzaki H, Noguchi M, Iwakura H, Fujikura J, Tanaka T, Ebihara K, Kawamura J, Komoto I, Kawaguchi Y, et al. (2005) GPR40 gene expression in human pancreas and insulinoma. Biochem Biophys Res Commun 338:1788-1790.
-
(2005)
Biochem Biophys Res Commun
, vol.338
, pp. 1788-1790
-
-
Tomita, T.1
Masuzaki, H.2
Noguchi, M.3
Iwakura, H.4
Fujikura, J.5
Tanaka, T.6
Ebihara, K.7
Kawamura, J.8
Komoto, I.9
Kawaguchi, Y.10
-
86
-
-
51649104136
-
Loss-of-function mutation of the GPR40 gene associates with abnormal stimulated insulin secretion by acting on intracellular calcium mobilization
-
Vettor R, Granzotto M, De Stefani D, Trevellin E, Rossato M, Farina MG, Milan G, Pilon C, Nigro A, Federspil G, et al. (2008) Loss-of-function mutation of the GPR40 gene associates with abnormal stimulated insulin secretion by acting on intracellular calcium mobilization. J Clin Endocrinol Metab 93:3541-3550.
-
(2008)
J Clin Endocrinol Metab
, vol.93
, pp. 3541-3550
-
-
Vettor, R.1
Granzotto, M.2
De Stefani, D.3
Trevellin, E.4
Rossato, M.5
Farina, M.G.6
Milan, G.7
Pilon, C.8
Nigro, A.9
Federspil, G.10
-
87
-
-
33845954973
-
Medium-chain fatty acids as ligands for orphan G protein-coupled receptor GPR84
-
Wang J, Wu X, Simonavicius N, Tian H, and Ling L (2006) Medium-chain fatty acids as ligands for orphan G protein-coupled receptor GPR84. J Biol Chem 281:34457-34464.
-
(2006)
J Biol Chem
, vol.281
, pp. 34457-34464
-
-
Wang, J.1
Wu, X.2
Simonavicius, N.3
Tian, H.4
Ling, L.5
-
88
-
-
1342281272
-
The identification of ligands at orphan G-protein coupled receptors
-
Wise A, Jupe SC, and Rees S (2004) The identification of ligands at orphan G-protein coupled receptors. Annu Rev Pharmacol Toxicol 44:43-66.
-
(2004)
Annu Rev Pharmacol Toxicol
, vol.44
, pp. 43-66
-
-
Wise, A.1
Jupe, S.C.2
Rees, S.3
-
89
-
-
33748209543
-
Colonic health: Fermentation and short chain fatty acids
-
Wong JM, de Souza R, Kendall CW, Emam A, and Jenkins DJ (2006) Colonic health: fermentation and short chain fatty acids. J Clin Gastroenterol 40:235-243.
-
(2006)
J Clin Gastroenterol
, vol.40
, pp. 235-243
-
-
Wong, J.M.1
de Souza, R.2
Kendall, C.W.3
Emam, A.4
Jenkins, D.J.5
-
90
-
-
0742305675
-
Short-chain fatty acids stimulate leptin production in adipocytes through the G protein-coupled receptor GPR41
-
Xiong Y, Miyamoto N, Shibata K, Valasek MA, Motoike T, Kedzierski RM, and Yanagisawa M (2004) Short-chain fatty acids stimulate leptin production in adipocytes through the G protein-coupled receptor GPR41. Proc Natl Acad Sci U S A 101:1045-1050.
-
(2004)
Proc Natl Acad Sci U S A
, vol.101
, pp. 1045-1050
-
-
Xiong, Y.1
Miyamoto, N.2
Shibata, K.3
Valasek, M.A.4
Motoike, T.5
Kedzierski, R.M.6
Yanagisawa, M.7
-
91
-
-
1642456656
-
Existence of GPR40 functioning in a human breast cancer cell line, MCF-7
-
Yonezawa T, Katoh K, and Obara Y (2004) Existence of GPR40 functioning in a human breast cancer cell line, MCF-7. Biochem Biophys Res Commun 314:805-809.
-
(2004)
Biochem Biophys Res Commun
, vol.314
, pp. 805-809
-
-
Yonezawa, T.1
Katoh, K.2
Obara, Y.3
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