PDE4 inhibitors as new anti-inflammatory drugs: Effects on cell trafficking and cell adhesion molecules expression

Pharmacology and Therapeutics

Volumn 106, Issue 3, 2005, Pages 269-297

  Sanz, María Jesús ^a   Cortijo, Julio ^a,b   Morcillo, Esteban J ^b  

^a UNIVERSITY OF VALENCIA   (Spain)

^b HOSPITAL GENERAL UNIVERSITARIO DE VALENCIA   (Spain)

Author keywords

Cell adhesion molecules; Chemokines; Cytokines; Inflammation; Phosphodiesterase 4 inhibitors

Indexed keywords

ANTIINFLAMMATORY AGENT; BETA ADRENERGIC RECEPTOR STIMULATING AGENT; CELL ADHESION MOLECULE; CHEMOKINE; CILOMILAST; CORTICOSTEROID; CYTOKINE; FORSKOLIN; IMMUNOGLOBULIN; INTEGRIN; INTERLEUKIN 8; ISOBUTYLMETHYLXANTHINE; ISOENZYME; PHOSPHODIESTERASE IV INHIBITOR; ROFLUMILAST; ROLIPRAM; SALBUTAMOL; SELECTIN; STEROID;

ANTIINFLAMMATORY ACTIVITY; B LYMPHOCYTE; BASOPHIL; CELL INTERACTION; CHEMOTAXIS; CHRONIC OBSTRUCTIVE LUNG DISEASE; CYTOKINE RELEASE; DENDRITIC CELL; DRUG ACTIVITY; DRUG EFFICACY; ENZYME METABOLISM; ENZYME SPECIFICITY; EOSINOPHIL; HUMAN; INFLAMMATORY CELL; LEUKOCYTE; LUNG LAVAGE; LYMPHOCYTE; MACROPHAGE; MAST CELL; MONOCYTE; NAUSEA; NEUTROPHIL; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; RESPIRATORY EPITHELIUM; REVIEW; SMOOTH MUSCLE FIBER; TH1 CELL; VOMITING;

3',5'-CYCLIC-NUCLEOTIDE PHOSPHODIESTERASE; AMINOPYRIDINES; ANTI-INFLAMMATORY AGENTS; BENZAMIDES; CARBOXYLIC ACIDS; CELL ADHESION MOLECULES; CELL MOVEMENT; CYCLOPROPANES; HUMANS; NITRILES; PHOSPHODIESTERASE INHIBITORS; PULMONARY DISEASE, CHRONIC OBSTRUCTIVE;

EID: 19444363467     PISSN: 01637258     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.pharmthera.2004.12.001     Document Type: Review

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