Endogenous interleukin-10 regulates hemodynamic parameters, leukocyte- endothelial cell interactions, and microvascular permeability during endotoxemia

Circulation Research

Volumn 83, Issue 11, 1998, Pages 1124-1131

  Hickey, Micheal J ^a   Issekutz, Andrew C ^b   Reinhardt, Paul H ^a   Fedorak, Richard N ^c   Kubes, Paul ^a  

^a UNIVERSITY OF CALGARY   (Canada)

^b DALHOUSIE UNIVERSITY   (Canada)

^c UNIVERSITY OF ALBERTA   (Canada)

Author keywords

Adhesion; Endotoxin; Microvascular Permeability; Selectin

Indexed keywords

ENDOTHELIAL LEUKOCYTE ADHESION MOLECULE 1; ENDOTOXIN; FORMYLMETHIONYLLEUCYLPHENYLALANINE; INTERLEUKIN 10; LIPOPOLYSACCHARIDE; PADGEM PROTEIN;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BLOOD PRESSURE REGULATION; BLOOD VESSEL PERMEABILITY; CELL INTERACTION; CONTROLLED STUDY; DOSE RESPONSE; EMBRYO; ENDOTHELIUM CELL; ENDOTOXEMIA; HEMODYNAMIC MONITORING; IMMUNOREGULATION; LEUKOCYTE ADHERENCE; MOUSE; NONHUMAN; PRIORITY JOURNAL;

EID: 0032583082     PISSN: 00097330     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.RES.83.11.1124     Document Type: Article

References (38)

1. Bogdan C, Vodovotz Y, Nathan C. Macrophage deactivation by interleukin 10. J Exp Med. 1991;174:1549-1555.
2. Bussolati B, Mariano F, Montrucchio G, Piccoli G, Camussi G. Modulatory effect of interleukin-10 on the production of platelet-activating factor and superoxide anion by human leukocytes. Immunology. 1997; 90:440-447.
3. Kasama T, Stricter RM, Lukacs NW, Burdick MD, Kunkel SL. Regulation of neutrophil-derived chemokine expression by IL-10. J Immunol. 1994;152:3559-3569.
4. Kasama T, Stricter RM, Lukacs NW, Lincoln PM, Burdick MD, Kunkel SL. Interleukin-10 expression and chemokine regulation during the evolution of murine type II collagen-induced arthritis. J Clin Invest. 1995; 95:2868-2876.
5. Fiorentino DF, Bond MW, Mosmann TR. Two types of mouse T helper cell, IV: Th2 clones secrete a factor that inhibits cytokine production by Th1 clones. J Exp Med. 1989;170:2081-2095.
6. Arock M, Zuany-Amorim C, Singer M, Benhamou M, Pretolani M. Interleukin-10 inhibits cytokine generation from mast cells. Eur J Immunol. 1996;26:166-170.
7. van Deventer SJH, Elson CO, Fedorak RN. Multiple doses of intravenous interleukin 10 in steroid-refractory Crohn's disease. Gastroenterology. 1997;113:383-389.
8. Gerard C, Bruyns C, Marchant A, Abramowicz D, Vandenabeele P, Delvaux A, Fiers W, Goldman M, Velu T. Interleukin 10 reduces the release of tumor necrosis factor and prevents lethality in experimental endotoxemia. J Exp Med. 1993;177:547-550.
9. Santucci L, Fiorucci S, Chiorean M, Brunori PM, Di Matteo FM, Sidoni A, Migliorati G, Morelli A. Interleukin 10 reduces lethality and hepatic injury induced by lipopolysaccharide in galactosamine-sensitized mice. Gastroenterology. 1996;111:736-744.
10. Berg DJ, Kuhn R, Rajewsky K, Muller W, Menon S, Davidson N, Grunig G, Rennick D. Interleukin-10 is a central regulator of the response to LPS in murine models of endotoxic shock and the Shwartzman reaction but not endotoxin tolerance. J Clin Invest. 1995;96:2339-2347.
11. Mayadas TN, Johnson RC, Rayburn H, Hynes RO, Wagner DD. Leukocyte rolling and extravasation are severely compromised in P-selectin-deficient mice. Cell. 1993;74:541-554.
12. 2 integrins in vivo. Proc Natl Acad Sci U S A. 1991;88:7538-7542.
13. Kishimoto TK, Anderson DC. The role of integrins in inflammation In: Gallin JI, Goldstein IM, Snyderman R, eds. Inflammation: Basic Principles and Clinical Correlates. 2nd Ed. New York, NY: Raven Press, Ltd; 1992:353-406.
14. 4-integrin supports leukocyte rolling and adhesion in chronically inflamed postcapillary venules in vivo. J Exp Med. 1996;181:1-12.
15. Kuhn R, Lohler J, Rennick D, Rajewsky K, Muller W. Interleukin-10-deficient mice develop chronic enterocolitis. Cell. 1993;75:263-274.
16. Walter UM, Ayer LM, Manning AM, Frenette PS, Wagner DD, Hynes RO, Wolitzky BA, Issekutz AC. Generation and characterization of a novel adhesion function blocking monoclonal antibody recognizing both rat and mouse E-selectin. Hybridoma. 1997;16:355-361.
17. Walter UM, Ayer LM, Wolitzky BA, Wagner DD, Hynes RO, Manning AM, Issekutz AC. Characterization of a novel adhesion function blocking monoclonal antibody to rat/mouse P-selectin generated in the P-selectin deficient mouse. Hybridoma. 1997;16:249-257.
18. Hickey MJ, Sharkey KA, Sihota EG, Reinhardt PH, MacMicking JD, Nathan C, Kubes P. Inducible nitric oxide synthase (iNOS)-deficient mice have enhanced leukocyte-endothelium interactions in endotoxemia. FASEB J. 1997;11:955-964.
19. Kubes P, Kanwar S. Histamine induces leukocyte rolling in post-capillary venules: A P-selectin-mediated event. J Immunol. 1994;152:3570-3577.
20. House SD, Lipowsky HH. Leukocyte-endothelium adhesion: Microhemodynamics in mesentery of the cat. Microvasc Res. 1987;34:363-379.
21. Kurose I, Kubes P, Wolf R, Anderson DC, Paulson J, Miyasaka M, Granger DN. Inhibition of nitric oxide production: mechanisms of vascular albumin leakage. Circ Res. 1993;73:164-171.
22. 4-integrin, P-selectin, and E-selectin in an allergic model of inflammation. J Exp Med. 1997;185: 1077-1087.
23. Wong J, Johnston B, Lee SS, Bullard DC, Smith CW, Beaudet AL, Kubes P. A minimal role for selectins in the recruitment of leukocytes into the inflamed liver microvasculature. J Clin Invest. 1997;99:2782-2790.
24. Warren JS, Yabroff KR, Remick DG, Kunkel SL, Chensue SW, Kunkel RG, Johnson KJ, Ward PA. Tumor necrosis factor participates in the pathogenesis of acute immune complex alveolitis in the rat. J Clin Invest. 1989;84:1873-1882.
25. Bradley PP, Priebat DA, Christensen RD, Rothstein G. Measurement of cutaneous inflammation: estimation of neutrophil content with an enzyme marker. J Invest Dermatol. 1982;78:206-209.
26. Broide DH, Sullivan S, Gifford T, Sriramarao P. Inhibition of pulmonary eosinophilia in P-selectin- and ICAM-1-deficient mice. Am J Respir Cell Mol Biol. 1998;18:218-225.
27. Kunkel EJ, Jung U, Bullard DC, Norman KE, Wolitzky BA, Vestweber D, Beaudet AL, Ley K. Absence of trauma-induced leukocyte rolling in mice deficient in both P-selectin and intercellular adhesion molecule-1. J Exp Med. 1996;183:57-65.
28. Marchant A, Bruyns C, Vandenabeele P, Ducarme M, Gerard C, Delvaux A, De Groote D, Abramowicz D, Velu T, Goldman M. IL-10 controls IFN-gamma and TNF production during experimental endotoxemia. Eur J Immunol. 1994;24:1167-1171.
29. Parrillo JE. Pathogenetic mechanisms of septic shock. N Engl J Med. 1993;328:1471-1477.
30. Hayward R, Nossuli T, Scalia R, Lefer AM. Cardioprotective effect of interleukin-10 in murine myocardial ischemia-reperfusion. Eur J Pharmacol. 1997;334:157-163.
31. Shostak A, Gotloib L. Increased mesenteric, diaphragmatic, and pancreatic interstitial albumin content in rats with acute abdominal sepsis. Shock. 1998;9:135-137.
32. Standiford TJ, Kunkel SL, Lukacs NW, Greenberger MJ, Danforth JM, Kunkel RG, Strieter RM. Macrophage inflammatory protein-1 alpha mediates lung leukocyte recruitment, lung capillary leak, and early mortality in murine endotoxemia. J Immunol. 1995;155:1515-1524.
33. Berg DJ, Leach MW, Kuhn R, Rajewsky K, Muller W, Davidson NJ, Rennick D. Interleukin 10 but not interleukin 4 is a natural suppressant of cutaneous inflammatory responses. J Exp Med. 1995;182:99-108.
34. Li L, Elliot JF, Mosmann TR. IL-10 inhibits cytokine production, vascular leakage, and swelling during T helper 1 cell-induced delayed-type hypersensitivity. J Immunol. 1994;153:3967-3978.
35. Mertz PM, Dewitt DL, Stetler-Stevenson WG, Wahl LM. Interleukin 10 suppression of monocyte prostaglandin H synthase-2: mechanism of inhibition of prostaglandin-dependent matrix metalloproteinase production. J Biol Chem. 1994;269:21322-21329.
36. Perry MA, Granger DN. Role of CD11/CD18 in shear-rate dependent leukocyte-endothelial cell interactions in cat mesenteric venules. J Clin Invest. 1991;87:1798-1804.
37. Lawrence MB, McIntire LV, Eskin SG. Effect of flow on polymorphonuclear leukocyte/endothelial cell adhesion. Blood. 1987;70: 1284-1290.
38. + TH1-like responses. J Clin Invest. 1996;98: 1010-1020.