The influence of endogenous catecholamines on the inhibitory effects of rolipram against early- and late-phase response to antigen in the guinea pig

Journal of Pharmacology and Experimental Therapeutics

Volumn 280, Issue 1, 1997, Pages 210-219

  Underwood, David C ^a   Matthews, Jane K ^a   Osborn, Ruth R ^a   Bochnowicz, Steven ^a   Torphy, Theodore J ^a  

^a GLAXOSMITHKLINE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ADRENALIN; BRL 61063; CATECHOLAMINE; CIMETIDINE; FILAMINAST; INDOMETACIN; NADOLOL; PHOSPHODIESTERASE; PHOSPHODIESTERASE INHIBITOR; PROPRANOLOL; PROSTAGLANDIN; PROSTAGLANDIN SYNTHASE; ROLIPRAM; SB 201609; UNCLASSIFIED DRUG;

ADRENALIN BLOOD LEVEL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASTHMA; BRONCHOSPASM; BRONCHUS REACTIVITY; CATECHOLAMINE RELEASE; CONTROLLED STUDY; EOSINOPHIL; GUINEA PIG; INFLAMMATION; INTRAVENOUS DRUG ADMINISTRATION; MAST CELL DEGRANULATION; NONHUMAN; ORAL DRUG ADMINISTRATION; PRIORITY JOURNAL;

ADRENALECTOMY; ANIMALS; ANTIGENS; CATECHOLAMINES; CIMETIDINE; GUINEA PIGS; INDOMETHACIN; MALE; NADOLOL; PHOSPHODIESTERASE INHIBITORS; PROPRANOLOL; PYRROLIDINONES; ROLIPRAM;

EID: 0030892025     PISSN: 00223565     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (59)

1. BARNES, P. J.: Endogenous catecholamines and asthma. J. Allergy Clin. Immunol. 677: 791-795, 1986.
2. BARNES, P., FITZGERALD, G., BROWN, M. AND DOLLERY, C.: Nocturnal asthma and changes in circulating epinephrine, histamine, and cortisol. N. Engl. J. Med. 303: 263-267, 1980.
3. BATES, M. E., CLAYTON, M., CALHOUN, W., JARJOUR, N., SCHRADER, L., GEIGER, K., SCHULTZ, T., SBDGWICK, J., SWENSON, C. AND BUSSE, W.: Relationship of plasma epinephrine and circulating eosinophils to nocturnal asthma. Am. J. Respir. Crit. Care Med. 149: 667-672, 1994.
4. BEAVO, J. A.: Multiple isozymes of cyclic nucleotide phosphodiesteraae. Adv. Second Messenger Phosphoprotein Res. 22: 1-30, 1977.
5. BRAVO, J. A. AND REIFSNYDER, D. H.: Primary sequence of cyclic nucleotide phosphodiesterase isozymes and the design of selective inhibitors. Trends Pharmacol. Sci. 11: 150-155, 1990.
6. BENSON, M. K., BERRILL, W. T., STERLING, G. M., DECALMER, P. B., CHATTERJEE, S.S., CROXSON, R. S. AND CRUICKBHANK, J. M.: Cardioselective and noncardioselective beta blockers in reversible obstructive airways disease. Postgrad. Med. J. 53: suppl. III, 143-148, 1977.
7. 4 and other agonists. Br. J. Pharmacol. 79: 839-848, 1983.
8. BOUHUYS, A., DOUGLAS, J. S. AND GUYATT, A. R.: Pharmacological modification of histamine-mediated airway responses. J. Clin. Invest. 50: 9a-10a, 1971.
9. BOURNE, H. R., LICHTENSTEIN, L. M., MELMON, K. L., HENNEY, C. S., WEINSTEIN, Y. AND SHEARER, G. M.: Modulation of inflammation and immunity by cyclic AMP. Science (Wash. DC) 184: 19-28, 1974.
10. BROOKS, P. J., DOLLERY, C. T. AND MACDERMOT, J.: Relationship between numbers of beta adrenergic receptors in lymphocytes and disease severity in asthma. J. Allergy Clin. Immunol. 63: 401-406, 1979.
11. BUCKLE, D. R., ARCH, J. R. S., CONNOLLY, B. J., FENWICK, A. E., FOSTER, K. A., MURRAY, K. J., READSHAW, S. A., SMALLRIDGE, M. AND SMITH, D. G.: Inhibition of cyclic nucleotide phosphodiesterase by derivatives of 1,3-bis (cyclopropylmethyl) xanthine. J. Med. Chem. 37: 470-485, 1994.
12. COLLIER, H. O. J. AND JAMES, G. W. L.: Humoral factors affecting pulmonary inflation during acute anaphylaxis in the guinea-pig in vivo. Br. J. Pharmacol. Chemother. 30: 283-301, 1967.
13. DE BOER, J., PHILPOTT, A. J., VAN AMSTERDAM, H. G. M., SHAHID, M., ZAAGSMA, J. AND NICHOLSON, C. D.: Human bronchial cyclic nucleotide phosphodiesterase isoenzymes: Biochemical and pharmacological analysis using selective inhibitors. Br. J. Pharmacol. 106: 1028-1034, 1992.
14. DENT, G., GIEMBYCZ, M. A., RABE, K. F. AND BARNES, P. J.: Inhibition of eosinophillic cyclic nucleotide PDE activity and opsonized, zymosan-stimulated respiratory burst by "type IV"-selective PDE inhibitors. Br. J. Pharmacol. 103: 1339-1346, 1991.
15. DIAMOND, L.: Potentiation of bronchomotor responses by beta adrenegic antagonists. J. Pharmacol. Exp. Ther. 181: 434-445, 1972.
16. ELLIOTT, K. R. F., BERRY, J. L., BATE, A. J., FOSTER, R. W., AND SMALL, R. C.: The isozyme selectivity of AH 21-132 as an inhibitor of cyclic nucleotide phosohodiesterase activity. J. Enzyme Inhibition 4: 245-251, 1990.
17. FORSTER, C. J., BURMAN, M., CIESLINSKI, L. B., MATHEWS, J. K., UNDERWOOD, D. C., TORPHY, T. J., BENDER, P. E., GUIDER, A. M., KIRRANE, T. M., KARPINSKI, J. M., RYAN, M. D. AND CHRISTENSEN, S. B.: Phenethyloxamides as selective phosphodiesterase IV inhibitors. 24th National Medicinal Chemistry Symposium, Salt Lake City, Utah, June 21-25, 1994.
18. FRASER, C., VENTER, J. C. AND KALINER, M.: Autonomic abnormalities and autoantibodies to beta-adrenergic receptors. N. Engl. J. Med. 305: 1165-1170, 1981.
19. GIEMBYCZ, M. A. AND DENT, G.: Prospects for selective nucleotide phosphodiesterase inhibitors in the treatment of bronchial asthma. Clin. Exp. Allergy 22: 337-344, 1992.
20. GIEMBYCZ, M. A. AND RAEBURN, D.: Putative substrates for cyclic nucleotide-dependent protein kinases and the control of airway smooth muscle tone. J. Auton. Pharmacol. 11: 365-398, 1991.
21. GREEN, S. A., TURKI, J., BEJARANO, P., HALL, I. P. AND LIGGETT, S. B: Influence of beta 2-adrenergic receptor genotypes on signal transduction in human airway smooth muscle cells. Am. J. Respir. Cell Mol. Biol. 13: 25-33, 1995.
22. GRISWOLD, D. E., WEBB, E. F., BRETON, J., WHITE, J. R., MARSHALL, P. J. AND TORPHY, T. J.: Effect of the selective phosphodiesterase type IV inhibitor, rolipram, on the fluid and cellular phases of the inflammatory response. Inflammation 17: 333-344, 1993.
23. HEASLIP, R. J., LOMBARDO, L. J., GOLANKIEWICZ, J. M. ILSEMANN, B. A., EVANS, D. Y., SICKELS, B. D., MUDRICK, J. K., BAGLI, J. AND WEICHMAN, B. M.: Phosphodiesterase-IV inhibition, respiratory muscle relaxation and bronchodilation by WAY-PDA-641. J. Pharmacol. Exp. Ther. 268: 888-896, 1994.
24. HOWELL, R. E., SICKELS, B. D. AND WOEPPEL, S. L.: Pulmonary antiallergic and bronchodilator effects of isozyme-selective phosphodiesterase inhibitors in guinea pigs. J. Pharmacol. Exp. Ther. 264: 609-701, 1993.
25. HOWE, R. AND SHANKS, R. G.: Optical isomers of propranolol. Nature 210: 1336-1338, 1966.
26. HULBERT, W. C., MCLEAN, T., WIGGS, B., PARE, P. D. AND HOGG, J. C.: Histamine dose-response curves in guinea pigs. J. Appl. Physiol. 58: 625-634, 1985.
27. KAUMANN, A. J. AND BLINKS, J. R.: Comparative potencies of beta adrenergic blocking agents on isolated heart muscle. Fed. Proc. 26: 401, 1967.
28. KUEHL, F. A., ZANETTI, M. E., SODERMAN, D. D., MILLER, D. K. AND HAM, E. A.: Cyclic AMP-dependent regulation of lipid mediators in white cells. A unifying concept for explaining the efficacy of theophylline in asthma. Am. Rev. Respir. Dis. 136: 210-213, 1987.
29. LEVY, B.: A comparison of the adrenergic receptor blocking properties of 1-(4′-methylphenyl)-2-isopropylamino-propanol-HCl and propranolol. J. Pharmacol. Exp. Ther. 156: 452-462, 1967.
30. 2. Nature (Lond.) 244: 287-8, 1973.
31. 2 antihistamine on "allergic" histamine release and its inhibition by histamine. J. Pharmacol. Exp. Ther. 192: 441-450, 1975.
32. MCNEILL, R. S.: Effect of a β-adrenergic-blocking agent, propranolol, on asthmatics, Lancet 2: 1101-1102, 1964.
33. NEY, U. M.: Propranolol-induced airway hyperreactivity in guinea-pigs. Br. J. Pharmac. 79: 1003-1009, 1983.
34. NIELSON, C. P. VESTAL, R. E., STURM, R. J. AND HEASLIP, R. J.: Effects of selective phosphodiesterase inhibitors on the polymorphonuclear leukocyte respiratory burst. J. Allergy Clin. Immunol. 86: 801-808, 1990.
35. PLAUT, M., MARONE, G., THOMAS, L. L. AND LICHTENSTEIN, L. M.: Cyclic nucleotides in immune responses and allergy. Adv. Cyclic Nucleotide Res. 12: 161-172, 1980.
36. 2-adrenergic receptor in normal and asthmatic subjects. Am. J. Respir. Cell Mol. Biol. 8: 334-339, 1993.
37. ROBISON, G. A., BUTCHER, R. W. AND SUTHERLAND, E. W., eds. Cyclic AMP and hormone action. In: Cyclic AMP, pp. 17-47, Academic Press, 1971.
38. SILVER, P. J., HAMEL, L. T., PERRONE, M. H., BENTLEY, R. G., BUSHOVER, C. R. AND EVANS, D. B.: Differential pharmacologic sensitivity of cyclic nucleotide phosphodiesterase isozymes isolated from cardiac muscle, arterial and airway smooth muscle. Eur. J. Pharmacol. 150: 85-94, 1988.
39. SKINNER, C., PALMER, K. N. V. AND KERRIDGE, D. F.: Comparison of the effects of acebutolol (Sectral) and proctolol (Eraldin) on airways obstruction in asthmatics. Br. J. Clin. Pharmac. 2: 417-422, 1975.
40. SOUNESS, J. E., CARTER, C. M., DIOCEE, B. K., HASSALL, G. A., WOOD, L. J. AND TURNER, N. C.: Characterization of guinea-pig eosinophil phosphodieaterase activity. Biochem. Pharmacol. 42: 937-945, 1991.
41. SPINA, D., RIGBY, P. J., PATERSON, J. W. AND GOLDIE, R. G.: Autoradiographic localization of beta-adrenoceptors in asthmatic human lung. Am. Rev. Respir. Dis. 140: 1410-1415, 1989.
42. STURM, R. S., OSBORN, M. C. AND HEASLIP, R. J.: The effect of phosphodiesterase inhibitors on pulmonary inflammatory cell influx in ovalbumin sensitized guinea pigs. J. Cell. Biochem. 14C: (Suppl.) 337, 1990.
43. SZENTIVANYI, A.: The beta-adrenergic theory of the atopic abnormality in bronchial asthma. J. Allergy 42: 203-232, 1968.
44. SZENTIVANYI, A., POLSON, J. B. AND SZENTIVANYI, J.: Issue of adrenoceptor behavior in respiratory and cutaneous disorders of atopic allergy. Trends Pharmacol. Sci. 5: 280-282, 1984.
45. TORPHY, T. J.: β-Adrenoceptors, cAMP and airway smooth muscle relaxation: Challenges to the dogma. Trends Pharmacol. Sci. 15: 370-374, 1994.
46. TORPHY, T. J. AND CIESLINSKI, L. B.: Characterization and selective inhibition of cyclic nucleotide phosphodiesterase isozymes in canine tracheal smooth muscle. Mol. Pharmacol. 37: 206-214, 1990.
47. TORPHY, T. J., LIVI, G. P., BALCAREK, J. M., WHITE, J. R., CHILTON, F. H., AND UNDEM, B. J.: Therapeutic potential of isozyme-selective phosphodiesterase inhibitors in the treatment of asthma. Adv. Second Messenger Phosphoprotein Res. 25: 289-305, 1992.
48. TORPHY, T. J. AND UNDEM, B. J.: Phosphodiesterase inhibitors: New opportunities for the treatment of asthma. Thorax 48: 512-523, 1991.
49. TORPHY, T. J., UNDEM, B. J., CIESLINKSI, L. B., LUTTMANN, M. M., REEVES, M. L. AND HAY, D. W. P.: Identification, characterization and functional role of phosphodiesterase isozymes in human airway smooth muscle. J. Pharmacol. Exper. Ther. 265: 1213-1223, 1993.
50. 2-adrenergic receptor autoantibodies in asthma. Am. J. Respir. Cell Mol. Biol. 12: 531-539, 1995.
51. UNDEM, B. J., PEACHELL, P. T. AND LICHTENSTEIN, L. M.: Isoproterenol-induced inhibition of immunoglobulin E-mediated release of histamine and arachidonic acid metabolites from the human lung mast cell. J. Pharmacol. Exp. Ther. 247: 209-217, 1988.
52. UNDEM, B. J., TORPHY, T. J., GOLDMAN, D. W., AND CHILTON, F. H.: Inhibition by 3′5′-adenosine monophosphate of eicosanoid and platelet activating factor biosynthesis in the mouse PT-18 mast cell. J. Biol. Chem. 265: 6750-6758, 1990.
53. UNDERWOOD, D. C., KOTZER, C. J. BOCHNIWICZ, S., OSBORN, R. R., LUTTMANN, M. A., HAY, D. W. P., AND TORPHY, T. J.: Comparison of phosphodiesterase III, IV and dual III/IV inhibitors on bronchospasm and pulmonary eosinophil influx in guinea pigs. J. Pharmacol. Exp. Ther. 270: 250-259, 1994.
54. UNDERWOOD, D. C., MATTHEWS, J. K., OSBORN, R. R., NOVAK, L. B., BOCHNOWICZ, S. AND MEUNIER, L.: Catecholamine and β-adrenoceptor influences on airway reactivity to antigen in guinea pigs. Int. Arch. Allergy Immunol. 109: 286-294, 1996a.
55. UNDERWOOD, D. C., OSBORN, R. R., NEWSHOLME, S. J., TORPHY, T. J. AND HAY, D. W. P.: Persistent airway eosinophilia after leukotriene (LT) D4 administration in the guinea pig. Am. J. Reap. Crit. Care Med. 154: (4), 1996b.
56. UNDERWOOD, D. C., OSBORN, R. R., NOVAK, L. B., MATTHEWS, J. K., NEWSHOLME, S. J., UNDEM, B.J., HAND, J. M. AND TORPHY, T. J.: Inhibition of antigen-induced bronchoconstriction and eosinophil infiltration in the guinea pig by the cyclic AMP-specific phosphodiesterase inhibitor, rolipram. J. Pharmacol. Exp. Ther. 266: 306-313, 1993.
57. 2-adrenergic receptors: A possible cause of adrenergic hyporesponsiveness in allergic rhinitis and asthma. Science (Wash. DC) 207: 1361-1363, 1980.
58. WEINREICH, D. AND UNDEM, B. J.: Immunological regulation of synaptic transmission in isolated guinea pig autonomic ganglia. J. Clin. Invest. 79: 1529-1532, 1987.
59. ZAID, G. AND BEALL, G. N.: Bronchial response to β-adrenergic blockade. N. Engl. J. Med. 275: 580-584, 1966.