Activation of the COOH-terminal Src kinase (Csk) by cAMP-dependent protein kinase inhibits signaling through the T cell receptor

Journal of Experimental Medicine

Volumn 193, Issue 4, 2001, Pages 497-507

  Vang, Torkel ^a   Torgersen, Knut Martin ^a   Sundvold, Vibeke ^a   Saxena, Manju ^b   Levy, Finn Olav ^a,d   Skålhegg, Bjørn S ^a   Hansson, Vidar ^a   Mustelin, Tomas ^b,c   Taskén, Kjetil ^a  

^a UNIVERSITY OF OSLO   (Norway)

^b LA JOLLA INSTITUTE FOR ALLERGY AND IMMUNOLOGY   (United States)

^c BURNHAM INSTITUTE   (United States)

^d MERCK RESEARCH LABORATORIES   (United States)

Author keywords

Csk; Immunomodulation; Protein kinase A; T cell activation; Tyrosine phosphorylation

Indexed keywords

CYCLIC AMP DEPENDENT PROTEIN KINASE; FORSKOLIN; INTERLEUKIN 2; PROTEIN TYROSINE KINASE; T LYMPHOCYTE RECEPTOR; TYROSINE;

ARTICLE; CONTROLLED STUDY; CYTOKINE RELEASE; ENZYME ACTIVATION; HUMAN; HUMAN CELL; IMMUNOMODULATION; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; REGULATORY MECHANISM; SIGNAL TRANSDUCTION; T LYMPHOCYTE ACTIVATION;

CELLS, CULTURED; CYCLIC AMP-DEPENDENT PROTEIN KINASES; ENZYME ACTIVATION; HUMANS; LYMPHOCYTE ACTIVATION; LYMPHOCYTE SPECIFIC PROTEIN TYROSINE KINASE P56(LCK); MEMBRANE MICRODOMAINS; MODELS, IMMUNOLOGICAL; PHOSPHORYLATION; PROTEIN-TYROSINE KINASES; RECEPTORS, ANTIGEN, T-CELL; SIGNAL TRANSDUCTION; T-LYMPHOCYTES;

EID: 0035910759     PISSN: 00221007     EISSN: None     Source Type: Journal    
DOI: 10.1084/jem.193.4.497     Document Type: Article

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