Chemokines in pathology and medicine

Journal of Internal Medicine

Volumn 250, Issue 2, 2001, Pages 91-104

  Baggiolini, M ^a  

^a UNIVERSITY OF BERN   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

CHEMOKINE; CHEMOKINE RECEPTOR; INTERLEUKIN 8;

DRUG MECHANISM; HUMAN; IMMUNE SYSTEM; IMMUNITY; INFLAMMATION; LEUKOCYTE; NONHUMAN; PATHOPHYSIOLOGY; PRIORITY JOURNAL; PROTEIN EXPRESSION; RECEPTOR BINDING; REVIEW; SIGNAL TRANSDUCTION;

ANIMALS; CHEMOKINES; HUMANS; RECEPTORS, CHEMOKINE; SIGNAL TRANSDUCTION; TERMINOLOGY;

EID: 0034829818     PISSN: 09546820     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2796.2001.00867.x     Document Type: Review

References (86)

1. Nomenclature announcement - The chemokines
2. Chemokines and leukocyte traffic
3. The role of chemokine receptors in primary, effector, and memory immune responses
4. Chemokines and their receptors in lymphocyte traffic and HIV infection
5. Chemokines and disease
6. Lymphocyte traffic control by chemokines
7. Dancing to the tune of chemokines
8. Viral exploitation and subversion of the immune system through chemokine mimicry
9. Interleukin-8 and related chemotactic cytokines - CXC and CC chemokines
10. Human chemokines: An update
11. A molecular cloning and functional characterization of human lymphotactin
12. 3C motif
13. Neurotactin, a membrane-anchored chemokine upregulated in brain inflammation
14. Solution structure and basis for functional activity of stromal cell-derived factor-1; dissociation of CXCR4 activation from binding and inhibition of HIV-1
15. Structure-activity relationships of chemokines
16. Three-dimensional structure of interleukin 8 in solution
17. Crystal structure of interleukin 8: Symbiosis of NMR and crystallography
18. Structural characterization of a monomeric chemokine: Monocyte chemoattractant protein-3
19. Chemokines: A new classification system and their role in immunity
20. The human N-cformylpeptide receptor. Characterization of two cDNA isolates and evidence for a new subfamily of G-protein-coupled receptors
21. Cloning of complementary DNA encoding a functional human interleukin-8 receptor
22. Structure and functional expression of a human interleukin-8 receptor
23. International union of pharmacology. XXII. Nomenclature for chemokine receptors
24. Scanning mutagenesis of interleukin-8 identifies a cluster of residues required for receptor binding
25. 2-terminal residues and evidence for uncoupling of neutrophil chemotaxis, exocytosis, and receptor binding activities
26. Platelet factor 4 binds to interleukin 8 receptors and activates neutrophils when its N terminus is modified with Glu-Leu-Arg
27. Structural requirements for interleukin-8 function identified by design of analogs and CXC chemokine hybrids
28. Structure-activity relationships of chemokines
29. N-terminal peptides of stromal cell-derived factor-1 with CXC chemokine receptor 4 agonist and antagonist activities
30. NMR studies of active N-terminal peptides of stromal cell-derived factor-1. Structural basis for receptor binding
31. Lysine 58 and histidine 66 at the C-terminal α-helix of monocyte chemoattractant protein-1 are essential for glycosaminoglycan binding
32. Stromal cell-derived factor-1α associates with heparan sulfates through the first β-strand of the chemokine
33. Binding to heparan sulfate or heparin enhances neutrophil responses to interleukin 8
34. Transcytosis and surface presentation of IL-8 ky venular endothelial cells
35. Mechanism of neutrophil activation by NAF, a novel monocyte-derived peptide agonist
36. Traffic signals for lymphocyte recirculation and leukocyte emigration: The multistep paradigm
37. Interleukin-2 regulates CC chemokine receptor expression and chemotactic responsiveness in T lymphocytes
38. Chemokines and chemokine receptors in T-cell priming and Th1/Th2-mediated responses
39. Differential expression of chemokine receptors and chemotactic responsiveness of type 1 T helper cells (Th1s) and Th2s
40. Flexible programs of chemokine receptor expression on human polarized T helper 1 and 2 lymphocytes
41. CCR5 is characteristic of Th1 lymphocytes
42. Functional expression of the eotaxin receptor CCR3 in T lymphocytes co-localizing with eosinophils
43. Two subsets of memory T lymphocytes with distinct homing potentials and effector functions
44. Preferential localization of effector memory cells in nonlymphoid tissue
45. Visualizing the generation of memory CD4 T cells in the whole body
46. Regulation by chemokines of circulating dendritic cell precursors, and the formation of portal tract-associated lymphoid tissue, in a granulomatous liver disease
47. A putative chemokine receptor, BLR1, directs B cell migration to defined lymphoid organs and specific anatomic compartments of the spleen
48. Expression of the G-protein-coupled receptor BLR1 defines mature, recirculating B cells and a subset of T-helper memory cells
49. Sequence variation of a novel heptahelical leucocyte receptor through alternative transcript formation
50. B cell-attracting chemokine 1, a human CXC chemokine expressed in lymphoid tissues, selectively attracts B lymphocytes via BLR1/CXCR5
51. AB-cell-homing chemokine made in lymphoid follicles activates Burkitt's lymphoma receptor-1
52. CCR7 coordinates the primary immune response by establishing functional microenvironments in secondary lymphoid organs
53. CXC chemokine receptor 5 expression defines follicular homing T cells with B cell helper function
54. Follicular B helper T cells express CXC chemokine receptor 5, localize to B cell follicles, and support immunoglobulin production
55. Follicular homing T helper (Th) cells and the Th1/Th2 paradigm
56. Chemokines and their receptors in allograft rejection
57. Targeting of the chemokine receptor CCR1 suppresses development of acute and chronic cardiac allograft rejection
58. Requirement of the chemokine receptor CXCR3 for acute allograft rejection
59. Chemokine receptor specific for IP10 and Mig: Structure, function, and expression in activated T-lymphocytes
60. CC chemokine receptor 2 is critical for induction of experimental autoimmune encephalomyelitis
61. Resistance to experimental autoimmune encephalomyelitis in mice lacking the CC chemokine receptor (CCR) 2
62. Control of TH2 polarization by the chemokine monocyte chemoattractant protein-1
63. Atherosclerosis - An inflammatory disease
64. An antagonist of monocyte chemoattractant protein 1 (MCP-1) inhibits arthritis in the MRL-lpr mouse model
65. Effect of a CC chemokine receptor antagonist on collagen induced arthritis in DBA/1 mice
66. Increased expression of IP-10, IL-8, MCP-1, and MCP-3 in ulcerative colitis
67. CC-chemokine receptor 5 polymorphism and age of onset in familial multiple sclerosis
68. The CCR5 deletion mutation fails to protect against multiple sclerosis
69. Association of rheumatoid arthritis with a functional chemokine receptor, CCR5
70. CC chemokine receptor 5 polymorphism in rheumatoid arthritis
71. Interleukin 8 receptor deficiency confers susceptibility to acute experimental pyelonephritis and may have a human counterpart
72. BCA-1 is highly expressed in Helicobacter pylori-induced mucosa-associated lymphoid tissue and gastric lymphoma
73. BLC expression in pancreatic islets causes B cell recruitment and lymphotoxin-dependent lymphoid neogenesis
74. Involvement of chemokine receptors in breast cancer metastasis
75. Antagonists of monocyte chemoattractant protein 1 identified by modification of functionally critical NH2-terminal residues
76. RANTES and MCP-3 antagonists bind multiple chemokine receptors
77. Extension of recombinant human RANTES by the retention of the initiating methionine produces a potent antagonist
78. Potent inhibition of HIV-1 infectivity in macrophages and lymphocytes by a novel CCR5 antagonist
79. Amino-terminally modified RANTES analogues demonstrate differential effects on RANTES receptors
80. Differential activation of CC chemokine receptors by AOP-RANTES
81. Met-RANTES reduces vascular and tubular damage during acute renal transplant rejection: Blocking monocyte arrest and recruitment
82. Blocking chemokine receptors
83. Chemokine receptor antagonists
84. Viral antichemokines: From pathogenesis to drug discovery
85. The ligands of CXC chemokine receptor 3, I-TAC, Mig, and IP10, are natural antagonists for CCR3
86. Eotaxin is a natural antagonist for CCR2 and an agonist for CCR5