Prostaglandin E2 stimulates IL-8 gene expression in human colonic epithelial cells by a posttranscriptional mechanism

Journal of Immunology

Volumn 161, Issue 7, 1998, Pages 3746-3752

  Yu, Yi ^a   Chadee, Kris ^a  

^a MCGILL UNIVERSITY   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

BUCLADESINE; CHLORAMPHENICOL ACETYLTRANSFERASE; CYCLIC AMP; CYCLIC AMP DEPENDENT PROTEIN KINASE; DEXAMETHASONE; FORSKOLIN; INTERLEUKIN 8; MESSENGER RNA; PHORBOL 13 ACETATE 12 MYRISTATE; PROSTAGLANDIN E RECEPTOR; PROSTAGLANDIN E2; PROSTAGLANDIN RECEPTOR STIMULATING AGENT; PROTEIN; TUMOR PROTEIN;

ARTICLE; COLON MUCOSA; CONTROLLED STUDY; CYTOKINE PRODUCTION; DOSE RESPONSE; ENZYME LINKED IMMUNOSORBENT ASSAY; GENE; GENE EXPRESSION; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; INFLAMMATION; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TRANSCRIPTION REGULATION; ADENOCARCINOMA; BIOSYNTHESIS; CELL CULTURE; COLON; COLON TUMOR; DRUG ANTAGONISM; DRUG EFFECT; DRUG POTENTIATION; EPITHELIUM CELL; GENE EXPRESSION REGULATION; GENETICS; IMMUNOLOGY; INTRACELLULAR FLUID; METABOLISM; PHYSIOLOGY; PROTEIN PROCESSING; SIGNAL TRANSDUCTION;

ADENOCARCINOMA; BUCLADESINE; COLON; COLONIC NEOPLASMS; CYCLIC AMP; DEXAMETHASONE; DINOPROSTONE; DOSE-RESPONSE RELATIONSHIP, IMMUNOLOGIC; EPITHELIAL CELLS; FORSKOLIN; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; INTERLEUKIN-8; INTRACELLULAR FLUID; NEOPLASM PROTEINS; PROTEIN PROCESSING, POST-TRANSLATIONAL; RECEPTORS, PROSTAGLANDIN E; RNA, MESSENGER; SIGNAL TRANSDUCTION; TETRADECANOYLPHORBOL ACETATE; TUMOR CELLS, CULTURED;

EID: 0032173437     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (7)

1. Baggiolini, M., B. Dewald, and B. Moser. 1994. Interleukin-8 and related chemotactic cytokines-CXC and CC chemokines. Adv. Immunol. 55:97.
2. Massion, P. P., H. Inoue, J. Richman-Eisenstat, D. Grunberger, P. G. Jorens, B. Housset, J. F. Pittet, J. P. Wiener-Kornish, and J. A. Nadel. 1994. Novel Pseudomonas product stimulates interleukin-8 production in airway epithelial cells in vitro. J. Clin. Invest. 93:26.
3. DiMango, E., H. J. Zar, R. Bryan, and A. Prince. 1995. Diverse Pseudomonas aeruginosa gene products stimulate respiratory epithelial cells to produce interleukin-8. J. Clin. Invest. 96:2204.
4. Schurer-Maly, C. C., L. Eckmann, M. F. Kagnoff, M. T. Falco, and F. E. Maly. 1994. Colonic epithelial cell lines as a source of interleukin-8: stimulation by inflammatory cytokines and bacterial lipopolysaccharide. Immunology 81:85.
5. Eckmann, L., H. C. Jung, C. Schurer-Maly, A. Panja, E. Morzycka-Wroblewska, and M. F. Kagnoff. 1993. Differential cytokine expression by human intestinal epithelial cell lines: regulated expression of interleukin 8. Gasteroenterology 105:1689.
6. Jung, H. C., L. Eckmann, S. K. Yang, A. Panja, J. Fierer, E. Morzycka-Wroblewska, and M. F. Kagnoff. 1995. A distinct array of proinflammatory cytokines is expressed in human colon epithelial cells in response to bacterial invasion. J. Clin. Invest. 95:55.
7. Crowe, S. E., L. Alvarez, M. Dytoc, R. H. Hunt, M. Muller, P. Sherman, J. Patel, Y. Jin, and P. B. Ernst. 1995. Expression of interleukin 8 and CD54 by human gastric epithelium after Helicobacter pylori infection in vitro. Gasterenterology 108:65.