Chemokines: Multiple levels of leukocyte migration control

Trends in Immunology

Volumn 25, Issue 2, 2004, Pages 75-84

  Moser, Bernhard ^a   Wolf, Marlene ^a   Walz, Alfred ^a   Loetscher, Pius ^b  

^a UNIVERSITY OF BERN   (Switzerland)

^b NOVARTIS PHARMA AG   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID; CATHEPSIN D; CATHEPSIN G; CATHEPSIN L; CHEMOKINE; CHEMOKINE RECEPTOR CCR1; CHEMOKINE RECEPTOR CCR10; CHEMOKINE RECEPTOR CCR2; CHEMOKINE RECEPTOR CCR3; CHEMOKINE RECEPTOR CCR5; CHEMOKINE RECEPTOR CXCR1; CHEMOKINE RECEPTOR CXCR2; CHEMOKINE RECEPTOR CXCR3; COLLAGENASE 3; ELASTASE; GELATINASE A; GELATINASE B; IMMUNOGLOBULIN FC FRAGMENT; INTERLEUKIN 8; INTERSTITIAL COLLAGENASE; MATRIX METALLOPROTEINASE; MATRIX METALLOPROTEINASE 14; NEUTROPHIL COLLAGENASE;

AMINO ACID SEQUENCE; ANTIBODY DEPENDENT ENHANCEMENT; EFFECTOR CELL; HUMAN; IMMUNOSURVEILLANCE; LEUKOCYTE MIGRATION INHIBITION; LEUKOPOIESIS; MEMORY CELL; MOLECULAR INTERACTION; MOLECULAR RECOGNITION; NATURAL KILLER CELL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN FAMILY; PROTEIN MOTIF; RECEPTOR OCCUPANCY; REVIEW; UPREGULATION;

EID: 0842324615     PISSN: 14714906     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.it.2003.12.005     Document Type: Review

References (81)

1. Gerard C., Rollins B.J. Chemokines and disease. Nat. Immunol. 2:2001;108-115.
2. Moser B., Loetscher P. Lymphocyte traffic control by chemokines. Nat. Immunol. 2:2001;123-128.
3. Murphy P.M., et al. International union of pharmacology. XXII. Nomenclature for chemokine receptors. Pharmacol. Rev. 52:2000;145-176.
4. Loetscher P., et al. Chemokines and their receptors in lymphocyte traffic and HIV infection. Adv. Immunol. 74:2000;127-180.
5. Zlotnik A., Yoshie O. Chemokines: a new classification system and their role in immunity. Immunity. 12:2000;121-127.
6. Proudfoot A.E. Chemokine receptors: multifaceted therapeutic targets. Nat. Rev. Immunol. 2:2002;106-115.
7. Wymann M.P., et al. Phosphoinositide 3-kinase signalling - which way to target? Trends Pharmacol. Sci. 24:2003;366-376.
8. Thelen M. Dancing to the tune of chemokines. Nat. Immunol. 2:2001;129-134.
9. Baggiolini M., et al. Interleukin-8 and related chemotactic cytokines - CXC and CC chemokines. Adv. Immunol. 55:1994;97-179.
10. Richmond A. NF-κB, chemokine gene transcription and tumour growth. Nat. Rev. Immunol. 2:2002;664-674.
11. Shortman K., Liu Y.J. Mouse and human dendritic cell subtypes. Nat. Rev. Immunol. 2:2002;151-161.
12. Gordon S. Pattern recognition receptors: doubling up for the innate immune response. Cell. 111:2002;927-930.
13. Loetscher P., Moser B. Homing chemokines in rheumatoid arthritis. Arthritis Res. 4:2002;233-236.
14. Gretz J.E., et al. Lymph-borne chemokines and other low molecular weight molecules reach high endothelial venules via specialized conduits while a functional barrier limits access to the lymphocyte microenvironments in lymph node cortex. J. Exp. Med. 192:2000;1425-1440.
15. Palframan R.T., et al. Inflammatory chemokine transport and presentation in HEV: a remote control mechanism for monocyte recruitment to lymph nodes in inflamed tissues. J. Exp. Med. 194:2001;1361-1373.
16. Janatpour M.J., et al. Tumor necrosis factor-dependent segmental control of MIG expression by high endothelial venules in inflamed lymph nodes regulates monocyte recruitment. J. Exp. Med. 194:2001;1375-1384.
17. Butcher E.C., et al. Lymphocyte trafficking and regional immunity. Adv. Immunol. 72:1999;209-253.
18. Ansel K.M., Cyster J.G. Chemokines in lymphopoiesis and lymphoid organ development. Curr. Opin. Immunol. 13:2001;172-179.
19. Clark-Lewis I., et al. Structure-activity relationships of chemokines. J. Leukoc. Biol. 57:1995;703-711.
20. Onuffer J.J., Horuk R. Chemokines, chemokine receptors and small-molecule antagonists: recent developments. Trends Pharmacol. Sci. 23:2002;459-467.
21. Levesque J.P., et al. Disruption of the CXCR4/CXCL12 chemotactic interaction during hematopoietic stem cell mobilization induced by GCSF or cyclophosphamide. J. Clin. Invest. 111:2003;187-196.
22. Petit I., et al. G-CSF induces stem cell mobilization by decreasing bone marrow SDF-1 and up-regulating CXCR4. Nat. Immunol. 3:2002;687-694.
23. Muller A., et al. Involvement of chemokine receptors in breast cancer metastasis. Nature. 410:2001;50-56.
24. Loetscher P., Clark-Lewis I. Agonistic and antagonistic activities of chemokines. J. Leukoc. Biol. 69:2001;881-884.
25. Loetscher P., et al. The ligands of CXC chemokine receptor 3, I-TAC, Mig, and IP10, are natural antagonists for CCR3. J. Biol. Chem. 276:2001;2986-2991.
26. Ogilvie P., et al. Eotaxin is a natural antagonist for CCR2 and an agonist for CCR5. Blood. 97:2001;1920-1924.
27. Blanpain C., et al. CCR5 binds multiple CC-chemokines: MCP-3 acts as a natural antagonist. Blood. 94:1999;1899-1905.
28. Savino W., et al. Intrathymic T-cell migration: a combinatorial interplay of extracellular matrix and chemokines? Trends Immunol. 23:2002;305-313.
29. Nagasawa T. A chemokine, SDF-1/PBSF, and its receptor, CXC chemokine receptor 4, as mediators of hematopoiesis. Int. J. Hematol. 72:2000;408-411.
30. Annunziato F., et al. Chemokines and lymphopoiesis in human thymus. Trends Immunol. 22:2001;277-281.
31. Bleul C.C., Boehm T. Chemokines define distinct microenvironments in the developing thymus. Eur. J. Immunol. 30:2000;3371-3379.
32. Wright D.E., et al. Hematopoietic stem cells are uniquely selective in their migratory response to chemokines. J. Exp. Med. 195:2002;1145-1154.
33. Lapidot T., Petit I. Current understanding of stem cell mobilization: the roles of chemokines, proteolytic enzymes, adhesion molecules, cytokines, and stromal cells. Exp. Hematol. 30:2002;973-981.
34. Reinhardt R.L., et al. Visualizing the generation of memory CD4 T cells in the whole body. Nature. 410:2001;101-105.
35. Masopust D., et al. Preferential localization of effector memory cells in nonlymphoid tissue. Science. 291:2001;2413-2417.
36. Sallusto F., Lanzavecchia A. Understanding dendritic cell and T-lymphocyte traffic through the analysis of chemokine receptor expression. Immunol. Rev. 177:2000;134-140.
37. Schaerli P., et al. CXC chemokine receptor 5 expression defines follicular homing T cells with B cell helper function. J. Exp. Med. 192:2000;1553-1562.
38. Breitfeld D., et al. Follicular B helper T cells express CXC chemokine receptor 5, localize to B cell follicles, and support immunoglobulin production. J. Exp. Med. 192:2000;1545-1552.
39. +T cells: follicular homing takes center stage in T-helper-cell responses. Trends Immunol. 23:2002;250-254.
40. Sprent J., Tough D.F. T cell death and memory. Science. 293:2001;245-248.
41. Lanzavecchia A., Sallusto F. Progressive differentiation and selection of the fittest in the immune response. Nat. Rev. Immunol. 2:2002;982-987.
42. Kaech S.M., et al. Effector and memory T-cell differentiation: implications for vaccine development. Nat. Rev. Immunol. 2:2002;251-262.
43. Sallusto F., et al. Two subsets of memory T lymphocytes with distinct homing potentials and effector functions. Nature. 401:1999;708-712.
44. Wherry E.J., et al. Lineage relationship and protective immunity of memory CD8 T cell subsets. Nat. Immunol. 4:2003;225-234.
45. Sallusto F., et al. Switch in chemokine receptor expression upon TCR stimulation reveals novel homing potential for recently activated T cells. Eur. J. Immunol. 29:1999;2037-2045.
46. Randolph D.A., et al. The role of CCR7 in Th1 and Th2 cell localization and delivery of B cell help in vivo. Science. 286:1999;2159-2162.
47. Campbell J.J., et al. CCR7 expression and memory T cell diversity in humans. J. Immunol. 166:2001;877-884.
48. Kim C.H., et al. Rules of chemokine receptor association with T cell polarization in vivo. J. Clin. Invest. 108:2001;1331-1339.
49. + T cells express functional CCR7. J. Immunol. 168:2002;5441-5447.
50. - memory T cells do not differ in immediate effector cell function. J. Immunol. 169:2002;638-641.
51. Champagne P., et al. Skewed maturation of memory HIV-specific CD8 T lymphocytes. Nature. 410:2001;106-111.
52. + T cell response. J. Immunol. 168:2002;5455-5464.
53. + memory cells in humans defined by HLA and CC chemokine ligand 19 tetramers. J. Immunol. 170:2003;2461-2468.
54. + T lymphocytes primed by myeloid or plasmacytoid dendritic cells. Eur. J. Immunol. 33:2003;474-482.
55. Lasagni L., et al. An alternatively spliced variant of CXCR3 mediates the inhibition of endothelial cell growth induced by IP-10, Mig, and I-TAC, and acts as functional receptor for platelet factor 4. J. Exp. Med. 197:2003;1537-1549.
56. Campbell J.J., et al. The chemokine receptor CCR4 in vascular recognition by cutaneous but not intestinal memory T cells. Nature. 400:1999;776-780.
57. + human thymocytes. J. Exp. Med. 196:2002;379-387.
58. + T cells represent major subsets of human peripheral blood memory T cells migrating in response to CCL1/I-309. Eur. J. Immunol. 32:2002;3506-3514.
59. + regulatory T cells. J. Exp. Med. 194:2001;847-853.
60. Kunkel E.J., et al. Lymphocyte CC chemokine receptor 9 and epithelial thymus-expressed chemokine (TECK) expression distinguish the small intestinal immune compartment: epithelial expression of tissue-specific chemokines as an organizing principle in regional immunity. J. Exp. Med. 192:2000;761-768.
61. Papadakis K.A., et al. CCR9-positive lymphocytes and thymus-expressed chemokine distinguish small bowel from colonic Crohn's disease. Gastroenterology. 121:2001;246-254.
62. Kunkel E.J., Butcher E.C. Chemokines and the tissue-specific migration of lymphocytes. Immunity. 16:2002;1-4.
63. + lymphocytes to the small-intestinal mucosa. J. Clin. Invest. 110:2002;1113-1121.
64. + gut intraepithelial lymphocytes. Blood. 98:2001;2626-2632.
65. Bowman E.P., et al. The intestinal chemokine thymus-expressed chemokine (CCL25) attracts IgA antibody-secreting cells. J. Exp. Med. 195:2002;269-275.
66. Kunkel E.J., et al. CCR10 expression is a common feature of circulating and mucosal epithelial tissue IgA Ab-secreting cells. J. Clin. Invest. 111:2003;1001-1010.
67. Lazarus N.H., et al. A common mucosal chemokine (mucosae-associated epithelial chemokine/CCL28) selectively attracts IgA plasmablasts. J. Immunol. 170:2003;3799-3805.
68. Hieshima K., et al. CCL28 has dual roles in mucosal immunity as a chemokine with broad-spectrum antimicrobial activity. J. Immunol. 170:2003;1452-1461.
69. Reiss Y., et al. CC chemokine receptor (CCR)4 and the CCR10 ligand cutaneous T cell-attracting chemokine (CTACK) in lymphocyte trafficking to inflamed skin. J. Exp. Med. 194:2001;1541-1547.
70. Soler D., et al. CCR4 versus CCR10 in human cutaneous Th lymphocyte trafficking. Blood. 101:2003;1677-1682.
71. Homey B., et al. CCL27-CCR10 interactions regulate T cell-mediated skin inflammation. Nat. Med. 8:2002;157-165.
72. Kunkel E.J., et al. Expression of the chemokine receptors CCR4, CCR5, and CXCR3 by human tissue-infiltrating lymphocytes. Am. J. Pathol. 160:2002;347-355.
73. Katou F., et al. Macrophage-derived chemokine (MDC/CCL22) and CCR4 are involved in the formation of T lymphocyte-dendritic cell clusters in human inflamed skin and secondary lymphoid tissue. Am. J. Pathol. 158:2001;1263-1270.
74. + lymphocytes into lesional atopic dermatitis skin. J. Invest. Dermatol. 115:2000;640-646.
75. Ferenczi K., et al. Increased CCR4 expression in cutaneous T cell lymphoma. J. Invest. Dermatol. 119:2002;1405-1410.
76. Horikawa T., et al. IFN-γ-inducible expression of thymus and activation-regulated chemokine/CCL17 and macrophage-derived chemokine/CCL22 in epidermal keratinocytes and their roles in atopic dermatitis. Int. Immunol. 14:2002;767-773.
77. +cells differentiate into Langerhans cells. Nat. Immunol. 2:2001;1151-1158.
78. Kurth I., et al. Monocyte selectivity and tissue localization suggests a role for breast and kidney-expressed chemokine (BRAK) in macrophage development. J. Exp. Med. 194:2001;855-861.
79. Merad M., et al. Langerhans cells renew in the skin throughout life under steady-state conditions. Nat. Immunol. 3:2002;1135-1141.
80. Cella M., et al. Plasmacytoid monocytes migrate to inflamed lymph nodes and produce large amounts of type I interferon. Nat. Med. 5:1999;919-923.
81. Proudfoot A.E., et al. Glycosaminoglycan binding and oligomerization are essential for the in vivo activity of certain chemokines. Proc. Natl. Acad. Sci. U. S. A. 100:2003;1885-1890.