The inhibition of antigen-induced eosinophilia and bronchoconstriction by CDP840, a novel stereo-selective inhibitor of phosphodiesterase type 4

British Journal of Pharmacology

Volumn 118, Issue 5, 1996, Pages 1183-1191

  Hughes, B ^a   Howat, D ^a   Lisle, H ^a   Holbrook, M ^a   James, T ^a   Gozzard, N ^a   Blease, K ^a   Hughes, P ^a   Kingaby, R ^a   Warrellow, G ^a   Alexander, R ^a   Head, J ^a   Boyd, E ^a   Eaton, M ^a   Perry, M ^a   Wales, M ^a   Smith, B ^a   Owens, R ^a   Catterall, C ^a   Lumb, S ^a   Russell, A ^a   Allen, R ^a   Merriman, M ^a   Bloxham, D ^a   Higgs, G ^a   more..

^a UCB PHARMA   (Belgium)

Author keywords

Allergic airway disease; Anti asthmatic; Anti inflammatory; Bronchoconstriction; CDP840; Eosinophilia; Esoinophil stabilization; Phosphodiesterase inhibitor; Rolipram; RP73401

Indexed keywords

4 [2 [3 (CYCLOPENTYLOXY) 4 METHOXYPHENYL] 2 PHENYLETHYL]PYRIDINE; ANTIGEN; DEXAMETHASONE; ERYTHROPOIETIN; HISTAMINE; INTERLEUKIN 5; OVALBUMIN; PHOSPHODIESTERASE INHIBITOR; PICLAMILAST; ROLIPRAM; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BRONCHOSPASM; CONTROLLED STUDY; DRUG STRUCTURE; EOSINOPHILIA; FEMALE; GUINEA PIG; IMMUNE RESPONSE; INTRAPERITONEAL DRUG ADMINISTRATION; INTRAVENOUS DRUG ADMINISTRATION; LUNG EXTRAVASCULAR FLUID; LUNG INFLATION; MALE; NONHUMAN; ORAL DRUG ADMINISTRATION; PLEURISY; PRIORITY JOURNAL; RAT; STEREOCHEMISTRY;

EID: 8944247744     PISSN: 00071188     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1476-5381.1996.tb15522.x     Document Type: Article

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