-
1
-
-
0028839684
-
Activation and selective inhibition of a cyclic AMP-specific phosphodiesterase, PDE-4D3
-
Alvarez R, Sette C, Yang D, Eglen RM, Wilhelm R, Shelton ER and Conti M (1995) Activation and selective inhibition of a cyclic AMP-specific phosphodiesterase, PDE-4D3. Mol Pharmacol 48:616-622.
-
(1995)
Mol Pharmacol
, vol.48
, pp. 616-622
-
-
Alvarez, R.1
Sette, C.2
Yang, D.3
Eglen, R.M.4
Wilhelm, R.5
Shelton, E.R.6
Conti, M.7
-
2
-
-
0028267522
-
Isolation of a cDNA encoding a human rolipram-sensitive cyclic AMP phosphodiesterase (PDE IVD)
-
Baecker PA, Obernolte R, Bach C, Yee C and Shelton ER (1994) Isolation of a cDNA encoding a human rolipram-sensitive cyclic AMP phosphodiesterase (PDE IVD). Gene 138:253-256.
-
(1994)
Gene
, vol.138
, pp. 253-256
-
-
Baecker, P.A.1
Obernolte, R.2
Bach, C.3
Yee, C.4
Shelton, E.R.5
-
3
-
-
0028802726
-
Cyclic nucleotide phosphodiesterases: Functional implications of multiple isoforms
-
Beavo JA (1995) Cyclic nucleotide phosphodiesterases: Functional implications of multiple isoforms. Physiol Rev 75:725-748.
-
(1995)
Physiol Rev
, vol.75
, pp. 725-748
-
-
Beavo, J.A.1
-
4
-
-
0028574848
-
Molecular biology of the cyclic AMP-specific cyclic nucleotide phosphodiesterases: A diverse family of regulatory enzymes
-
Bolger GB (1994) Molecular biology of the cyclic AMP-specific cyclic nucleotide phosphodiesterases: A diverse family of regulatory enzymes. Cell Signalling 8:851-859.
-
(1994)
Cell Signalling
, vol.8
, pp. 851-859
-
-
Bolger, G.B.1
-
5
-
-
0027454556
-
A family of human phosphodiesterases homologous to the dunce learning and memory gene product of Drosophila melanogaster are potential targets for antidepressant drugs
-
Bolger G, Michaeli T, Martins T, St. John T, Steiner B, Rodgers L, Riggs M, Wichael M and Ferguson K (1993) A family of human phosphodiesterases homologous to the dunce learning and memory gene product of Drosophila melanogaster are potential targets for antidepressant drugs. Mol Cell Biol 13:6558-6571.
-
(1993)
Mol Cell Biol
, vol.13
, pp. 6558-6571
-
-
Bolger, G.1
Michaeli, T.2
Martins, T.3
St. John, T.4
Steiner, B.5
Rodgers, L.6
Riggs, M.7
Wichael, M.8
Ferguson, K.9
-
6
-
-
33847612208
-
Adenosine 3′,5′-phosphate in biological materials
-
Butcher RW and Sutherland EW (1962) Adenosine 3′,5′-phosphate in biological materials. J Biol Chem 237:1244-1250.
-
(1962)
J Biol Chem
, vol.237
, pp. 1244-1250
-
-
Butcher, R.W.1
Sutherland, E.W.2
-
7
-
-
0026468803
-
Structure and regulation of the rat high-affinity cyclic AMP phosphodiesterases: A family of closely related enzymes
-
Conti M, Swinnen JV, Tsikalas KE and Jin SLC (1992) Structure and regulation of the rat high-affinity cyclic AMP phosphodiesterases: A family of closely related enzymes. Adv Second Messenger Phosphoprotein Res 25:87-99.
-
(1992)
Adv Second Messenger Phosphoprotein Res
, vol.25
, pp. 87-99
-
-
Conti, M.1
Swinnen, J.V.2
Tsikalas, K.E.3
Jin, S.L.C.4
-
8
-
-
0029666141
-
Effects of IL-10 and IL-4 on LPS-induced transcription factors (AP-1, NF-IL-6, and NF-kappa B) which are involved in IL-6 regulation
-
Dokter WHA, Koopmans SB and Vellenga E (1996) Effects of IL-10 and IL-4 on LPS-induced transcription factors (AP-1, NF-IL-6, and NF-kappa B) which are involved in IL-6 regulation. Leukemia 10:1308-1316.
-
(1996)
Leukemia
, vol.10
, pp. 1308-1316
-
-
Dokter, W.H.A.1
Koopmans, S.B.2
Vellenga, E.3
-
9
-
-
0025789094
-
Enhancers and transcription factors controlling the inducibility of the TNF-alpha promoter in primary macrophages
-
Drouet C, Shakhov AN and Jongeneel CV (1991) Enhancers and transcription factors controlling the inducibility of the TNF-alpha promoter in primary macrophages. J Immunol 147:1694-1700.
-
(1991)
J Immunol
, vol.147
, pp. 1694-1700
-
-
Drouet, C.1
Shakhov, A.N.2
Jongeneel, C.V.3
-
10
-
-
0028919271
-
Molecular cloning and functional expression in yeast of a human cAMP-specific phosphodiesterase subtype (PDE IV-C)
-
Engels P, Sullivan M, Muller T and Lubbert H (1995) Molecular cloning and functional expression in yeast of a human cAMP-specific phosphodiesterase subtype (PDE IV-C). FEBS Lett 358:305-310.
-
(1995)
FEBS Lett
, vol.358
, pp. 305-310
-
-
Engels, P.1
Sullivan, M.2
Muller, T.3
Lubbert, H.4
-
11
-
-
0029005315
-
Molecular cloning of a novel splice variant of human type IVA (PDE-IVA) cyclic AMP phosphodiesterase and localization of the gene to the p13.2-q12 region of human chromosome 19
-
Horton YM, Sullivan M and Houslay MD (1995) Molecular cloning of a novel splice variant of human type IVA (PDE-IVA) cyclic AMP phosphodiesterase and localization of the gene to the p13.2-q12 region of human chromosome 19. Biochem J 308:683-691.
-
(1995)
Biochem J
, vol.308
, pp. 683-691
-
-
Horton, Y.M.1
Sullivan, M.2
Houslay, M.D.3
-
12
-
-
0027384590
-
NF-kappa B subunit-specific regulation of the interleukin-8 promoter
-
Kunsch C and Rosen CA (1993) NF-kappa B subunit-specific regulation of the interleukin-8 promoter. Mol Cell Biol 13:6137-6146.
-
(1993)
Mol Cell Biol
, vol.13
, pp. 6137-6146
-
-
Kunsch, C.1
Rosen, C.A.2
-
13
-
-
0025370222
-
Cloning and expression of cDNA for a human low-Km, rolipram-sensitive cyclic AMP phosphodiesterase
-
Livi GP, Kmetz P, Mchale MM, Cieslinski LB, Sathe GM, Taylor DP, Davis RL, Torphy TJ and Balcarek JM (1990) Cloning and expression of cDNA for a human low-Km, rolipram-sensitive cyclic AMP phosphodiesterase. Mol Cell Biol 10:2678-2686.
-
(1990)
Mol Cell Biol
, vol.10
, pp. 2678-2686
-
-
Livi, G.P.1
Kmetz, P.2
Mchale, M.M.3
Cieslinski, L.B.4
Sathe, G.M.5
Taylor, D.P.6
Davis, R.L.7
Torphy, T.J.8
Balcarek, J.M.9
-
14
-
-
0029146718
-
Diversity in cyclic nucleotide phosphodiesterase isozyme families
-
Manganiello VC, Murata T, Taira M, Belfrage P and Degerman E (1995) Diversity in cyclic nucleotide phosphodiesterase isozyme families. Arch Biochem Biophys 322: 1-13.
-
(1995)
Arch Biochem Biophys
, vol.322
, pp. 1-13
-
-
Manganiello, V.C.1
Murata, T.2
Taira, M.3
Belfrage, P.4
Degerman, E.5
-
15
-
-
0030075351
-
Prolonged beta adrenoceptor stimulation up-regulates cAMP phosphodiesterase activity in human monocytes by increasing mRNA and protein for phosphodiesterases 4A and 4B
-
Manning CD, McLaughlin MM, Livi GP, Cieslinski LB, Torphy TJ and Barnette MS (1996) Prolonged beta adrenoceptor stimulation up-regulates cAMP phosphodiesterase activity in human monocytes by increasing mRNA and protein for phosphodiesterases 4A and 4B. J Pharmacol Exp Ther 276:810-818.
-
(1996)
J Pharmacol Exp Ther
, vol.276
, pp. 810-818
-
-
Manning, C.D.1
McLaughlin, M.M.2
Livi, G.P.3
Cieslinski, L.B.4
Torphy, T.J.5
Barnette, M.S.6
-
16
-
-
0027339578
-
A low-Km, rolipram-sensitive, cAMP-specific phosphodiesterase from human brain: Cloning and expression of cDNA, biochemical characterization of recombinant protein, and tissue distribution of mRNA
-
McLaughlin MM, Cieslinski LB, Burman M, Torphy TJ and Livi GP (1993) A low-Km, rolipram-sensitive, cAMP-specific phosphodiesterase from human brain: Cloning and expression of cDNA, biochemical characterization of recombinant protein, and tissue distribution of mRNA. J Biol Chem 268:6470-6476.
-
(1993)
J Biol Chem
, vol.268
, pp. 6470-6476
-
-
McLaughlin, M.M.1
Cieslinski, L.B.2
Burman, M.3
Torphy, T.J.4
Livi, G.P.5
-
17
-
-
0028239635
-
Chromosome localizations of genes for five cAMP-specific phosphodiesterases in man and mouse
-
Milatovich A, Bolger G, Michaeli T and Francke U (1994) Chromosome localizations of genes for five cAMP-specific phosphodiesterases in man and mouse. Somatic Cell Mol Genet 20:75-86.
-
(1994)
Somatic Cell Mol Genet
, vol.20
, pp. 75-86
-
-
Milatovich, A.1
Bolger, G.2
Michaeli, T.3
Francke, U.4
-
18
-
-
0001074646
-
Subtypes of the type 4 cAMP phosphodiesterases: Structure, regulation and selective inhibition
-
Muller T, Engles P and Fozard JR (1995) Subtypes of the type 4 cAMP phosphodiesterases: Structure, regulation and selective inhibition. Trends Pharmacol Sci 17:294-298.
-
(1995)
Trends Pharmacol Sci
, vol.17
, pp. 294-298
-
-
Muller, T.1
Engles, P.2
Fozard, J.R.3
-
19
-
-
0026501412
-
Macrophage differentiation-specific expression of NF-IL-6, a transcription factor for interleukin-6
-
Natsuka S, Akira S, Nishio Y, Hashimoto S, Sugita T, Isshiki H and Kishimoto T (1992) Macrophage differentiation-specific expression of NF-IL-6, a transcription factor for interleukin-6. Blood 79:460-466.
-
(1992)
Blood
, vol.79
, pp. 460-466
-
-
Natsuka, S.1
Akira, S.2
Nishio, Y.3
Hashimoto, S.4
Sugita, T.5
Isshiki, H.6
Kishimoto, T.7
-
20
-
-
0029015560
-
Inhibition by interleukin-10 of inducible cyclooxygenase expression in lipopolysaccharide-stimulated monocytes: Its underlying mechanism in comparison with interleukin-4
-
Niiro H, Otsuka T, Tanabe T, Hara S, Kuga S, Nemoto Y, Tanaka Y, Nakashima H, Kitajima S and Abe M (1995) Inhibition by interleukin-10 of inducible cyclooxygenase expression in lipopolysaccharide-stimulated monocytes: Its underlying mechanism in comparison with interleukin-4. Blood 85:3736-3745.
-
(1995)
Blood
, vol.85
, pp. 3736-3745
-
-
Niiro, H.1
Otsuka, T.2
Tanabe, T.3
Hara, S.4
Kuga, S.5
Nemoto, Y.6
Tanaka, Y.7
Nakashima, H.8
Kitajima, S.9
Abe, M.10
-
21
-
-
0027244894
-
Isolation of a cDNA encoding a human rolipram-sensitive cyclic AMP phosphodiesterase (PDE IVD)
-
Obernolte R, Bhakta S, Alvarez R, Bach C, Zuppan P, Mulkins M, Jarnagin K and Shelton ER (1993) Isolation of a cDNA encoding a human rolipram-sensitive cyclic AMP phosphodiesterase (PDE IVD). Gene 129:239-247.
-
(1993)
Gene
, vol.129
, pp. 239-247
-
-
Obernolte, R.1
Bhakta, S.2
Alvarez, R.3
Bach, C.4
Zuppan, P.5
Mulkins, M.6
Jarnagin, K.7
Shelton, E.R.8
-
23
-
-
0028567253
-
The CREB/ATF family of transcription factors: Modulation by reversible phosphorylation
-
Papavassiliou AG (1994) The CREB/ATF family of transcription factors: Modulation by reversible phosphorylation. Anticancer Res 14:1801-1805.
-
(1994)
Anticancer Res
, vol.14
, pp. 1801-1805
-
-
Papavassiliou, A.G.1
-
24
-
-
0026499517
-
The regulation of the human TNF alpha promoter region in macrophage, T cell, and B cell lines
-
Rhoades KL, Golub SH and Economou JS (1992) The regulation of the human TNF alpha promoter region in macrophage, T cell, and B cell lines. J Biol Chem 267:22102-22107.
-
(1992)
J Biol Chem
, vol.267
, pp. 22102-22107
-
-
Rhoades, K.L.1
Golub, S.H.2
Economou, J.S.3
-
25
-
-
0027462624
-
Synergism between protein-kinase C and cAMP-dependent pathways in the expression of the interleukin-1 beta gene is mediated via the activator-protein-1 (AP-1) enhancer activity
-
Serkkola E, and Hurme M (1993) Synergism between protein-kinase C and cAMP-dependent pathways in the expression of the interleukin-1 beta gene is mediated via the activator-protein-1 (AP-1) enhancer activity. Eur J Biochem 213:243-249.
-
(1993)
Eur J Biochem
, vol.213
, pp. 243-249
-
-
Serkkola, E.1
Hurme, M.2
-
26
-
-
0030006920
-
Phosphorylation and activation of a cAMP-specific phosphodiesterase by the cAMP-dependent protein kinase. Involvement of serine-54 in the enzyme activation
-
Sette C and Conti M (1996) Phosphorylation and activation of a cAMP-specific phosphodiesterase by the cAMP-dependent protein kinase. Involvement of serine-54 in the enzyme activation. J Biol Chem 271:16526-16534.
-
(1996)
J Biol Chem
, vol.271
, pp. 16526-16534
-
-
Sette, C.1
Conti, M.2
-
27
-
-
0028198615
-
Modulation of cellular responses by hormones: Role of cAMP specific, rolipram-sensitive phosphodiesterases
-
Sette C, Vicini E and Conti M (1994) Modulation of cellular responses by hormones: Role of cAMP specific, rolipram-sensitive phosphodiesterases. Mol Cell Endocrinol 100:75-79.
-
(1994)
Mol Cell Endocrinol
, vol.100
, pp. 75-79
-
-
Sette, C.1
Vicini, E.2
Conti, M.3
-
28
-
-
0024405251
-
Molecular cloning of rat homologues of the Drosophila melanogaster dunce cAMF phosphodiesterase: Evidence for a family of genes
-
Swinnen JV, Joseph DR and Conti M (1989) Molecular cloning of rat homologues of the Drosophila melanogaster dunce cAMF phosphodiesterase: Evidence for a family of genes. Proc Natl Acad Sci USA 86:5325-5329.
-
(1989)
Proc Natl Acad Sci USA
, vol.86
, pp. 5325-5329
-
-
Swinnen, J.V.1
Joseph, D.R.2
Conti, M.3
-
29
-
-
0026010201
-
Properties and hormonal regulation of two structurally related cAMP phosphodiesterases from the rat sertoli cells
-
Swinnen JV, Tsikalas KE and Conti M (1991) Properties and hormonal regulation of two structurally related cAMP phosphodiesterases from the rat Sertoli cells. J Biol Chem 166:18370-18377.
-
(1991)
J Biol Chem
, vol.166
, pp. 18370-18377
-
-
Swinnen, J.V.1
Tsikalas, K.E.2
Conti, M.3
-
30
-
-
0028872186
-
Chromosomal localization of the human and rat genes (PDE4D and PDE4B) encoding the cAMP-specific phosphodiesterases 3 and 4
-
Szpirer C, Szpirer J, Riviere M, Swinnen J, Vicini E and Conti M (1995) Chromosomal localization of the human and rat genes (PDE4D and PDE4B) encoding the cAMP-specific phosphodiesterases 3 and 4. Cytogenet Cell Genet 69:11-14.
-
(1995)
Cytogenet Cell Genet
, vol.69
, pp. 11-14
-
-
Szpirer, C.1
Szpirer, J.2
Riviere, M.3
Swinnen, J.4
Vicini, E.5
Conti, M.6
-
31
-
-
0031914520
-
Phosphodiesterase isozymes: Molecular targets for novel anti-asthma agents
-
Torphy TJ (1998) Phosphodiesterase Isozymes: Molecular targets for novel anti-asthma agents. Am J Respir Crit Care Med 157:351-370.
-
(1998)
Am J Respir Crit Care Med
, vol.157
, pp. 351-370
-
-
Torphy, T.J.1
-
32
-
-
0028881807
-
Salbutamol up-regulates PDE4 activity and induces a heterologous desensitization of U937 cells to prostaglandin E2. Implications for the therapeutic use of beta-adrenoceptor agonists
-
Torphy TJ, Zhou HL, Foley JJ, Sarau HM, Manning CD and Barnette MS (1995) Salbutamol up-regulates PDE4 activity and induces a heterologous desensitization of U937 cells to prostaglandin E2. Implications for the therapeutic use of beta-adrenoceptor agonists. J Biol Chem 270:23598-23604.
-
(1995)
J Biol Chem
, vol.270
, pp. 23598-23604
-
-
Torphy, T.J.1
Zhou, H.L.2
Foley, J.J.3
Sarau, H.M.4
Manning, C.D.5
Barnette, M.S.6
-
33
-
-
0028998011
-
Regulation of distinct cyclic AMP-specific phosphodiesterase (phosphodiesterase type 4) isozymes in human monocytic cells
-
Verghese MW, McConnell RT, Lenhard RT, Hamacher L and Jin SLC (1995) Regulation of distinct cyclic AMP-specific phosphodiesterase (phosphodiesterase type 4) isozymes in human monocytic cells. Mol Pharmacol 47:1164-1171.
-
(1995)
Mol Pharmacol
, vol.47
, pp. 1164-1171
-
-
Verghese, M.W.1
McConnell, R.T.2
Lenhard, R.T.3
Hamacher, L.4
Jin, S.L.C.5
-
34
-
-
0021336885
-
Isolation of human mononuclear cell subsets by counterflow centrifugal elutriation (CCE): I. Characterization of B-lymphocyte-, T-lymphocyte-, and monocyte-enriched fractions by flow cytometric analysis
-
Wahl LM, Katona IM, Wilder RL, Winter CC, Haroui B, Scher I and Wahl SM (1994) Isolation of human mononuclear cell subsets by counterflow centrifugal elutriation (CCE): I. Characterization of B-lymphocyte-, T-lymphocyte-, and monocyte-enriched fractions by flow cytometric analysis. Cell Immunol 85:373-383.
-
(1994)
Cell Immunol
, vol.85
, pp. 373-383
-
-
Wahl, L.M.1
Katona, I.M.2
Wilder, R.L.3
Winter, C.C.4
Haroui, B.5
Scher, I.6
Wahl, S.M.7
-
35
-
-
0028281708
-
Interleukin-10 inhibits interleukin-8 production in human neutrophils
-
Wang P, Wu P, Anthes JC, Siegel MI, Egan RW and Billah MM (1994a) Interleukin-10 inhibits interleukin-8 production in human neutrophils. Blood 83:2678-2683.
-
(1994)
Blood
, vol.83
, pp. 2678-2683
-
-
Wang, P.1
Wu, P.2
Anthes, J.C.3
Siegel, M.I.4
Egan, R.W.5
Billah, M.M.6
-
36
-
-
0028365152
-
IL-10 inhibits transcription of cytokine genes in human peripheral blood mononuclear cells
-
Wang P, Wu P, Siegel MI, Egan RW and Billah MM (1994b) IL-10 inhibits transcription of cytokine genes in human peripheral blood mononuclear cells. J Immunol 153:811-816.
-
(1994)
J Immunol
, vol.153
, pp. 811-816
-
-
Wang, P.1
Wu, P.2
Siegel, M.I.3
Egan, R.W.4
Billah, M.M.5
-
37
-
-
0028948176
-
Interleukin (IL)-10 inhibits nuclear factor kB (NFkB) activation in human monocytes
-
Wang P, Wu P, Siegel MI, Egan RW and Billah MM (1995) Interleukin (IL)-10 inhibits nuclear factor kB (NFkB) activation in human monocytes. J Biol Chem 270:9558-9563.
-
(1995)
J Biol Chem
, vol.270
, pp. 9558-9563
-
-
Wang, P.1
Wu, P.2
Siegel, M.I.3
Egan, R.W.4
Billah, M.M.5
-
38
-
-
0026526503
-
Tumor necrosis factor alpha and interferon gamma synergistically induce interleukin 8 production in a human gastric cancer cell line through acting concurrently on AP-1 and NF-kB-like binding sites of the interleukin-8 gene
-
Yasumoto K, Okamoto S, Mukaida N, Murakami S, Mai M and Matsushima K (1992) Tumor necrosis factor alpha and interferon gamma synergistically induce interleukin 8 production in a human gastric cancer cell line through acting concurrently on AP-1 and NF-kB-like binding sites of the interleukin-8 gene. J Biol Chem 267:22506-22511.
-
(1992)
J Biol Chem
, vol.267
, pp. 22506-22511
-
-
Yasumoto, K.1
Okamoto, S.2
Mukaida, N.3
Murakami, S.4
Mai, M.5
Matsushima, K.6
-
39
-
-
0027299890
-
Regulation of the interleukin-1 beta (IL-1 beta) gene by mycobacterial components and lipopolysaccharide is mediated by two nuclear factor-IL-6 motifs
-
Zhang Y and Rom WN (1993) Regulation of the interleukin-1 beta (IL-1 beta) gene by mycobacterial components and lipopolysaccharide is mediated by two nuclear factor-IL-6 motifs. Mol Cell Biol 10:3831-3837.
-
(1993)
Mol Cell Biol
, vol.10
, pp. 3831-3837
-
-
Zhang, Y.1
Rom, W.N.2
|