메뉴 건너뛰기




Volumn 25, Issue 3, 2004, Pages 158-163

Antidepressant effects of inhibitors of cAMP phosphodiesterase (PDE4)

Author keywords

[No Author keywords available]

Indexed keywords

2 AMINO 4,5 DIHYDRO 6 METHYL 5 OXO 4 PROPYL 1,2,4 TRIAZOLO[1,5 A]PYRIMIDINE; 4 (3 BUTOXY 4 METHOXYBENZYL) 2 IMIDAZOLIDINONE; ANTIDEPRESSANT AGENT; CYCLIC AMP; CYCLIC GMP; DESIPRAMINE; DIZOCILPINE; FLUOXETINE; N METHYL DEXTRO ASPARTIC ACID RECEPTOR BLOCKING AGENT; PHOSPHODIESTERASE IV; PHOSPHODIESTERASE IV INHIBITOR; ROLIPRAM;

EID: 1342264246     PISSN: 01656147     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tips.2004.01.003     Document Type: Review
Times cited : (273)

References (59)
  • 1
    • 0020000847 scopus 로고
    • Characteristic behavioral alterations in rats induced by rolipram and other selective adenosine cyclic 3′,5′-monophosphate phosphodiesterase inhibitors
    • Wachtel H. Characteristic behavioral alterations in rats induced by rolipram and other selective adenosine cyclic 3′,5′-monophosphate phosphodiesterase inhibitors. Psychopharmacology (Berl.). 77:1982;309-316.
    • (1982) Psychopharmacology (Berl.) , vol.77 , pp. 309-316
    • Wachtel, H.1
  • 2
    • 0020693045 scopus 로고
    • Potential antidepressant activity of rolipram and other selective cyclic adenosine 3′,5′-monophosphate phosphodiesterase inhibitors
    • Wachtel H. Potential antidepressant activity of rolipram and other selective cyclic adenosine 3′,5′-monophosphate phosphodiesterase inhibitors. Neuropharmacology. 22:1983;267-272.
    • (1983) Neuropharmacology , vol.22 , pp. 267-272
    • Wachtel, H.1
  • 3
    • 0021720605 scopus 로고
    • Results of a phase II study of the antidepressant effect of rolipram
    • Zeller E. Results of a phase II study of the antidepressant effect of rolipram. Pharmacopsychiatry. 17:1984;188-190.
    • (1984) Pharmacopsychiatry , vol.17 , pp. 188-190
    • Zeller, E.1
  • 4
    • 0022003192 scopus 로고
    • Selective inhibition of one of the cyclic AMP phosphodiesterases from rat brain by the neurotrophic compound rolipram
    • Nemoz G., et al. Selective inhibition of one of the cyclic AMP phosphodiesterases from rat brain by the neurotrophic compound rolipram. Biochem. Pharmacol. 34:1985;2997-3000.
    • (1985) Biochem. Pharmacol. , vol.34 , pp. 2997-3000
    • Nemoz, G.1
  • 5
    • 0034024182 scopus 로고    scopus 로고
    • Phosphodiesterase 4 inhibitors and the treatment of asthma: Where are we now and where do we go from here?
    • Giembycz M.A. Phosphodiesterase 4 inhibitors and the treatment of asthma: where are we now and where do we go from here? Drugs. 59:2000;193-212.
    • (2000) Drugs , vol.59 , pp. 193-212
    • Giembycz, M.A.1
  • 6
    • 0035409208 scopus 로고    scopus 로고
    • Immunotherapeutic and antitumor potential of thalidomide analogues
    • Marriott J.B., et al. Immunotherapeutic and antitumor potential of thalidomide analogues. Expert Opin. Biol. Ther. 1:2001;675-682.
    • (2001) Expert Opin. Biol. Ther. , vol.1 , pp. 675-682
    • Marriott, J.B.1
  • 7
    • 0029979738 scopus 로고    scopus 로고
    • Mapping the functional domains of human recombinant phosphodiesterase 4A: Structural requirements for catalytic activity and rolipram binding
    • Jacobitz S., et al. Mapping the functional domains of human recombinant phosphodiesterase 4A: structural requirements for catalytic activity and rolipram binding. Mol. Pharmacol. 50:1996;891-899.
    • (1996) Mol. Pharmacol. , vol.50 , pp. 891-899
    • Jacobitz, S.1
  • 8
    • 0034009080 scopus 로고    scopus 로고
    • Regulation of cAMP and cGMP signaling: New phosphodiesterases and new functions
    • Soderling J.H., Beavo J.A. Regulation of cAMP and cGMP signaling: new phosphodiesterases and new functions. Curr. Opin. Cell Biol. 12:2000;174-179.
    • (2000) Curr. Opin. Cell Biol. , vol.12 , pp. 174-179
    • Soderling, J.H.1    Beavo, J.A.2
  • 9
    • 0035193364 scopus 로고    scopus 로고
    • Cyclic nucleotide phosphodiesterases: Relating structure and function
    • Francis S.H., et al. Cyclic nucleotide phosphodiesterases: relating structure and function. Prog. Nucleic Acid Res. Mol. Biol. 65:2001;1-52.
    • (2001) Prog. Nucleic Acid Res. Mol. Biol. , vol.65 , pp. 1-52
    • Francis, S.H.1
  • 11
    • 0031939478 scopus 로고    scopus 로고
    • Characterization of the rolipram-sensitive, cyclic AMP-specific phosphodiesterases: Identification and differential expression of immunologically distinct forms in the rat brain
    • Iona S., et al. Characterization of the rolipram-sensitive, cyclic AMP-specific phosphodiesterases: identification and differential expression of immunologically distinct forms in the rat brain. Mol. Pharmacol. 53:1998;23-32.
    • (1998) Mol. Pharmacol. , vol.53 , pp. 23-32
    • Iona, S.1
  • 12
    • 0033519275 scopus 로고    scopus 로고
    • Cyclic AMP phosphodiesterases are localized in regions of the mouse brain associated with reinforcement, movement, and affect
    • Cherry J.A., Davis R.L. Cyclic AMP phosphodiesterases are localized in regions of the mouse brain associated with reinforcement, movement, and affect. J. Comp. Neurol. 407:1999;287-301.
    • (1999) J. Comp. Neurol. , vol.407 , pp. 287-301
    • Cherry, J.A.1    Davis, R.L.2
  • 13
    • 0035224063 scopus 로고    scopus 로고
    • Sub-family selective actions in the ability of Erk2 MAP kinase to phosphorylate and regulate the activity of PDE4 cyclic AMP-specific phosphodiesterases
    • Baillie G.S., et al. Sub-family selective actions in the ability of Erk2 MAP kinase to phosphorylate and regulate the activity of PDE4 cyclic AMP-specific phosphodiesterases. Br. J. Pharmacol. 131:2000;811-819.
    • (2000) Br. J. Pharmacol. , vol.131 , pp. 811-819
    • Baillie, G.S.1
  • 14
    • 0023787143 scopus 로고
    • The effect of a selective phosphodiesterase inhibitor, rolipram, on muricide in olfactory bulbectomized rats
    • Mizokawa T., et al. The effect of a selective phosphodiesterase inhibitor, rolipram, on muricide in olfactory bulbectomized rats. Jpn. J. Pharmacol. 48:1988;357-364.
    • (1988) Jpn. J. Pharmacol. , vol.48 , pp. 357-364
    • Mizokawa, T.1
  • 15
    • 0024833641 scopus 로고
    • Antidepressant effects of rolipram in a genetic animal model of depression: Cholinergic supersensitivity and weight gain
    • Overstreet D.H., et al. Antidepressant effects of rolipram in a genetic animal model of depression: cholinergic supersensitivity and weight gain. Pharmacol. Biochem. Behav. 34:1989;691-696.
    • (1989) Pharmacol. Biochem. Behav. , vol.34 , pp. 691-696
    • Overstreet, D.H.1
  • 16
    • 0026034739 scopus 로고
    • Calcium-independent phosphodiesterase inhibitors as putative antidepressants: [3-(bicycloalkyloxy)-4-methoxyphenyl]-2-imidazolidinones
    • Saccomano N.A., et al. Calcium-independent phosphodiesterase inhibitors as putative antidepressants: [3-(bicycloalkyloxy)-4-methoxyphenyl]-2- imidazolidinones. J. Med. Chem. 34:1991;291-298.
    • (1991) J. Med. Chem. , vol.34 , pp. 291-298
    • Saccomano, N.A.1
  • 17
    • 0027493954 scopus 로고
    • Antidepressant-like effects of rolipram and other inhibitors of cyclic adenosine monophosphate phosphodiesterase on behavior maintained by differential reinforcement of low response rate
    • O'Donnell J.M. Antidepressant-like effects of rolipram and other inhibitors of cyclic adenosine monophosphate phosphodiesterase on behavior maintained by differential reinforcement of low response rate. J. Pharmacol. Exp. Ther. 264:1993;1168-1178.
    • (1993) J. Pharmacol. Exp. Ther. , vol.264 , pp. 1168-1178
    • O'Donnell, J.M.1
  • 18
    • 0036581252 scopus 로고    scopus 로고
    • Regulation of neurogenesis in adult mouse hippocampus by cAMP and the cAMP response element-binding protein
    • Nakagawa S., et al. Regulation of neurogenesis in adult mouse hippocampus by cAMP and the cAMP response element-binding protein. J. Neurosci. 22:2002;3673-3682.
    • (2002) J. Neurosci. , vol.22 , pp. 3673-3682
    • Nakagawa, S.1
  • 19
    • 0042528720 scopus 로고    scopus 로고
    • Requirement of hippocampal neurogenesis for the behavioral effects of antidepressants
    • Santarelli L., et al. Requirement of hippocampal neurogenesis for the behavioral effects of antidepressants. Science. 301:2003;805-809.
    • (2003) Science , vol.301 , pp. 805-809
    • Santarelli, L.1
  • 20
    • 0024269472 scopus 로고
    • Is phosphodiesterase inhibition a new mechanism of antidepressant action? a double-blind double-dummy study between rolipram and desipramine in hospitalized major and/or endogenous depressives
    • Bonbon D., et al. Is phosphodiesterase inhibition a new mechanism of antidepressant action? A double-blind double-dummy study between rolipram and desipramine in hospitalized major and/or endogenous depressives. Eur. Arch. Psychiatry Neurol. Sci. 238:1988;2-6.
    • (1988) Eur. Arch. Psychiatry Neurol. Sci. , vol.238 , pp. 2-6
    • Bonbon, D.1
  • 21
    • 0024217733 scopus 로고
    • Clinical and biochemical effects of the selective phosphodiesterase inhibitor rolipram in depressed inpatients controlled by determination of plasma level
    • Laux G., et al. Clinical and biochemical effects of the selective phosphodiesterase inhibitor rolipram in depressed inpatients controlled by determination of plasma level. Pharmacopsychiatry. 21:1988;378-379.
    • (1988) Pharmacopsychiatry , vol.21 , pp. 378-379
    • Laux, G.1
  • 22
    • 0026539996 scopus 로고
    • A multicenter double-blind study of three different doses of the new cAMP-phosphodiesterase inhibitor rolipram in patients with major depressive disorder
    • Fleischhacker W.W., et al. A multicenter double-blind study of three different doses of the new cAMP-phosphodiesterase inhibitor rolipram in patients with major depressive disorder. Neuropsychobiology. 26:1992;59-64.
    • (1992) Neuropsychobiology , vol.26 , pp. 59-64
    • Fleischhacker, W.W.1
  • 23
    • 0033043309 scopus 로고    scopus 로고
    • Emesis induced by inhibitors of type IV cyclic nucleotide phosphodiesterase (PDE IV) in the ferret
    • Robichaud A., et al. Emesis induced by inhibitors of type IV cyclic nucleotide phosphodiesterase (PDE IV) in the ferret. Neuropharmacology. 38:1999;289-297.
    • (1999) Neuropharmacology , vol.38 , pp. 289-297
    • Robichaud, A.1
  • 24
    • 0345192302 scopus 로고    scopus 로고
    • Preliminary evidence for an involvement of the cholinergic system in the sedative effects of rolipram in rats
    • Silvestre J.S., et al. Preliminary evidence for an involvement of the cholinergic system in the sedative effects of rolipram in rats. Pharmacol. Biochem. Behav. 64:1999;1-5.
    • (1999) Pharmacol. Biochem. Behav. , vol.64 , pp. 1-5
    • Silvestre, J.S.1
  • 25
    • 0030909059 scopus 로고    scopus 로고
    • Pharmacology of antidepressants
    • Frazer A. Pharmacology of antidepressants. J. Clin. Psychopharmacol. 17:(Suppl. 1):1997;2S-18S.
    • (1997) J. Clin. Psychopharmacol. , vol.17 , Issue.SUPPL. 1
    • Frazer, A.1
  • 26
    • 0029923241 scopus 로고    scopus 로고
    • Diminished noradrenergic stimulation reduces the activity of rolipram-sensitive, high-affinity cyclic AMP phosphodiesterase in rat cerebral cortex
    • Ye Y., O'Donnell J.M. diminished noradrenergic stimulation reduces the activity of rolipram-sensitive, high-affinity cyclic AMP phosphodiesterase in rat cerebral cortex. J. Neurochem. 66:1996;1894-1902.
    • (1996) J. Neurochem. , vol.66 , pp. 1894-1902
    • Ye, Y.1    O'Donnell, J.M.2
  • 27
    • 0030657498 scopus 로고    scopus 로고
    • Noradrenergic activity differentially regulates the expression of rolipram-sensitive, high-affinity cyclic AMP phosphodiesterase (PDE4) in rat brain
    • Ye Y., et al. Noradrenergic activity differentially regulates the expression of rolipram-sensitive, high-affinity cyclic AMP phosphodiesterase (PDE4) in rat brain. J. Neurochem. 69:1997;2397-2404.
    • (1997) J. Neurochem. , vol.69 , pp. 2397-2404
    • Ye, Y.1
  • 28
    • 0037174646 scopus 로고    scopus 로고
    • Targeting of cyclic AMP degradation to beta 2-adrenergic receptors by beta-arrestins
    • Perry S.J., et al. Targeting of cyclic AMP degradation to beta 2-adrenergic receptors by beta-arrestins. Science. 298:2002;834-836.
    • (2002) Science , vol.298 , pp. 834-836
    • Perry, S.J.1
  • 29
    • 0037417890 scopus 로고    scopus 로고
    • Beta-arrestin-mediated PDE4 cAMP phosphodiesterase recruitment regulates beta-adrenoceptor switching from Gs to Gi
    • Baillie G.S., et al. Beta-arrestin-mediated PDE4 cAMP phosphodiesterase recruitment regulates beta-adrenoceptor switching from Gs to Gi. Proc. Natl. Acad. Sci. U. S. A. 100:2003;940-945.
    • (2003) Proc. Natl. Acad. Sci. U. S. A. , vol.100 , pp. 940-945
    • Baillie, G.S.1
  • 30
    • 0033556178 scopus 로고    scopus 로고
    • Chronic antidepressant administration increases the expression of cAMP-specific phosphodiesterase 4A and 4B isoforms
    • Takahashi M., et al. chronic antidepressant administration increases the expression of cAMP-specific phosphodiesterase 4A and 4B isoforms. J. Neurosci. 19:1999;610-618.
    • (1999) J. Neurosci. , vol.19 , pp. 610-618
    • Takahashi, M.1
  • 31
    • 0033952296 scopus 로고    scopus 로고
    • Effects of repeated antidepressant treatment on type 4A phosphodiesterase (PDE4A) in rat brain
    • Ye Y., et al. Effects of repeated antidepressant treatment on type 4A phosphodiesterase (PDE4A) in rat brain. J. Neurochem. 74:2000;1257-1262.
    • (2000) J. Neurochem. , vol.74 , pp. 1257-1262
    • Ye, Y.1
  • 32
    • 0036913698 scopus 로고    scopus 로고
    • Regulation of cAMP phosphodiesterase mRNAs expression in rat brain by acute and chronic fluoxetine treatment. An in situ hybridization study
    • Miro X., et al. Regulation of cAMP phosphodiesterase mRNAs expression in rat brain by acute and chronic fluoxetine treatment. An in situ hybridization study. Neuropharmacology. 43:2002;1148-1157.
    • (2002) Neuropharmacology , vol.43 , pp. 1148-1157
    • Miro, X.1
  • 33
    • 0030006920 scopus 로고    scopus 로고
    • Phosphorylation and activation of a cAMP-specific phosphodiesterase by the cAMP-dependent protein kinase. Involvement of serine 54 in the enzyme activation
    • Sette C., Conti M. Phosphorylation and activation of a cAMP-specific phosphodiesterase by the cAMP-dependent protein kinase. Involvement of serine 54 in the enzyme activation. J. Biol. Chem. 271:1996;16526-16534.
    • (1996) J. Biol. Chem. , vol.271 , pp. 16526-16534
    • Sette, C.1    Conti, M.2
  • 34
    • 0033558010 scopus 로고    scopus 로고
    • The MAP kinase ERK2 inhibits the cyclic AMP-specific phosphodiesterase HSPDE4D3 by phosphorylating it at Ser579
    • Hoffmann R., et al. The MAP kinase ERK2 inhibits the cyclic AMP-specific phosphodiesterase HSPDE4D3 by phosphorylating it at Ser579. EMBO J. 18:1999;893-903.
    • (1999) EMBO J. , vol.18 , pp. 893-903
    • Hoffmann, R.1
  • 35
    • 0037183973 scopus 로고    scopus 로고
    • Cyclic AMP-dependent transcriptional up-regulation of phosphodiesterase 4D5 in human airway smooth muscle cells. Identification and characterization of a novel PDE4D5 promoter
    • Le Jeune R., et al. Cyclic AMP-dependent transcriptional up-regulation of phosphodiesterase 4D5 in human airway smooth muscle cells. Identification and characterization of a novel PDE4D5 promoter. J. Biol. Chem. 277:2002;35980-35989.
    • (2002) J. Biol. Chem. , vol.277 , pp. 35980-35989
    • Le Jeune, R.1
  • 36
    • 0038178990 scopus 로고    scopus 로고
    • Phosphodiesterase regulation is critical for the differentiation and pattern of gene expression in granulose cells of the ovarian follicle
    • Park J.Y., et al. Phosphodiesterase regulation is critical for the differentiation and pattern of gene expression in granulose cells of the ovarian follicle. Mol. Endocrinol. 17:2003;1117-1130.
    • (2003) Mol. Endocrinol. , vol.17 , pp. 1117-1130
    • Park, J.Y.1
  • 37
    • 0025157918 scopus 로고
    • Functional antagonists at the NMDA receptor complex exhibit antidepressant actions
    • Trullas R., Skolnick P. Functional antagonists at the NMDA receptor complex exhibit antidepressant actions. Eur. J. Pharmacol. 185:1990;1-10.
    • (1990) Eur. J. Pharmacol. , vol.185 , pp. 1-10
    • Trullas, R.1    Skolnick, P.2
  • 38
    • 0027967222 scopus 로고
    • Antidepressant activity of non-competitive and competitive NMDA receptor antagonists in a chronic mild stress model of depression
    • Papp M., Moryl E. Antidepressant activity of non-competitive and competitive NMDA receptor antagonists in a chronic mild stress model of depression. Eur. J. Pharmacol. 263:1994;1-7.
    • (1994) Eur. J. Pharmacol. , vol.263 , pp. 1-7
    • Papp, M.1    Moryl, E.2
  • 39
    • 0027503851 scopus 로고
    • MK-801 and enantiomers: Potential antidepressants or false positives in classical screening models
    • Panconi E., et al. MK-801 and enantiomers: potential antidepressants or false positives in classical screening models. Pharmacol. Biochem. Behav. 46:1993;15-20.
    • (1993) Pharmacol. Biochem. Behav. , vol.46 , pp. 15-20
    • Panconi, E.1
  • 40
    • 0034051217 scopus 로고    scopus 로고
    • Inhibition of cyclic AMP phosphodiesterase (PDE4) reverses memory deficits associated with NMDA receptor antagonism
    • Zhang H.T., et al. Inhibition of cyclic AMP phosphodiesterase (PDE4) reverses memory deficits associated with NMDA receptor antagonism. Neuropsychopharmacology. 23:2000;198-204.
    • (2000) Neuropsychopharmacology , vol.23 , pp. 198-204
    • Zhang, H.T.1
  • 41
    • 0036088736 scopus 로고    scopus 로고
    • Hydrolysis of N-methyl-D-aspartate receptor-stimulated cAMP and cGMP by PDE4 and PDE2 phosphodiesterases in primary neuronal cultures of rat cerebral cortex and hippocampus
    • Suvarna N.U., O'Donnell J.M. Hydrolysis of N-methyl-D-aspartate receptor-stimulated cAMP and cGMP by PDE4 and PDE2 phosphodiesterases in primary neuronal cultures of rat cerebral cortex and hippocampus. J. Pharmacol. Exp. Ther. 302:2002;249-256.
    • (2002) J. Pharmacol. Exp. Ther. , vol.302 , pp. 249-256
    • Suvarna, N.U.1    O'Donnell, J.M.2
  • 42
    • 0037458648 scopus 로고    scopus 로고
    • Cyclic AMP-specific PDE4 phosphodiesterases as critical components of cyclic AMP signaling
    • Conti M., et al. Cyclic AMP-specific PDE4 phosphodiesterases as critical components of cyclic AMP signaling. J. Biol. Chem. 278:2003;5493-5496.
    • (2003) J. Biol. Chem. , vol.278 , pp. 5493-5496
    • Conti, M.1
  • 43
    • 0036790883 scopus 로고    scopus 로고
    • Antidepressant-like profile and reduced sensitivity to rolipram in mice deficient in the PDE4D phosphodiesterase enzyme
    • Zhang H.T., et al. Antidepressant-like profile and reduced sensitivity to rolipram in mice deficient in the PDE4D phosphodiesterase enzyme. Neuropsychopharmacology. 27:2002;587-595.
    • (2002) Neuropsychopharmacology , vol.27 , pp. 587-595
    • Zhang, H.T.1
  • 44
    • 0035976546 scopus 로고    scopus 로고
    • Localization of phosphodiesterase-4 isoforms in the medulla and nodose ganglion of the squirrel monkey
    • Lamontagne S., et al. Localization of phosphodiesterase-4 isoforms in the medulla and nodose ganglion of the squirrel monkey. Brain Res. 920:2001;84-96.
    • (2001) Brain Res. , vol.920 , pp. 84-96
    • Lamontagne, S.1
  • 45
    • 0036790480 scopus 로고    scopus 로고
    • Deletion of phosphodiesterase 4D in mice shortens alpha(2)-adrenoceptor- mediated anesthesia, a behavioral correlate of emesis
    • Robichaud A., et al. Deletion of phosphodiesterase 4D in mice shortens alpha(2)-adrenoceptor-mediated anesthesia, a behavioral correlate of emesis. J. Clin. Invest. 110:2002;1045-1052.
    • (2002) J. Clin. Invest. , vol.110 , pp. 1045-1052
    • Robichaud, A.1
  • 46
    • 0022459284 scopus 로고
    • Stereospecific binding of the antidepressant rolipram to brain protein structures
    • Schneider H.H., et al. Stereospecific binding of the antidepressant rolipram to brain protein structures. Eur. J. Pharmacol. 127:1986;105-115.
    • (1986) Eur. J. Pharmacol. , vol.127 , pp. 105-115
    • Schneider, H.H.1
  • 47
    • 0030925148 scopus 로고    scopus 로고
    • Proposal for pharmacologically distinct conformers of PDE4 cyclic AMP phosphodiesterases
    • Souness J.E., Rao S. Proposal for pharmacologically distinct conformers of PDE4 cyclic AMP phosphodiesterases. Cell. Signal. 9:1997;227-236.
    • (1997) Cell. Signal. , vol.9 , pp. 227-236
    • Souness, J.E.1    Rao, S.2
  • 48
    • 0025339594 scopus 로고
    • Close correlation between behavioural response and binding in vivo for inhibitors of the rolipram-sensitive phosphodiesterase
    • Schmiechen R., et al. Close correlation between behavioural response and binding in vivo for inhibitors of the rolipram-sensitive phosphodiesterase. Psychopharmacology (Berl.). 102:1990;17-20.
    • (1990) Psychopharmacology (Berl.) , vol.102 , pp. 17-20
    • Schmiechen, R.1
  • 49
    • 0029021668 scopus 로고
    • Inhibitors of phosphodiesterase IV (PDE IV) increase acid secretion in rabbit isolated gastric glands: Correlation between function and interaction with high-affinity rolipram binding site
    • Barnette M.S., et al. Inhibitors of phosphodiesterase IV (PDE IV) increase acid secretion in rabbit isolated gastric glands: correlation between function and interaction with high-affinity rolipram binding site. J. Pharmacol. Exp. Ther. 273:1995;1396-1402.
    • (1995) J. Pharmacol. Exp. Ther. , vol.273 , pp. 1396-1402
    • Barnette, M.S.1
  • 50
    • 0029075880 scopus 로고
    • The ability of phosphodiesterase IV inhibitors to suppress superoxide production in guinea pig eosinophils is correlated with inhibition of phosphodiesterase IV catalytic activity
    • Barnette M.S., et al. The ability of phosphodiesterase IV inhibitors to suppress superoxide production in guinea pig eosinophils is correlated with inhibition of phosphodiesterase IV catalytic activity. J. Pharmacol. Exp. Ther. 273:1995;674-679.
    • (1995) J. Pharmacol. Exp. Ther. , vol.273 , pp. 674-679
    • Barnette, M.S.1
  • 51
    • 13344295098 scopus 로고    scopus 로고
    • 3H]rolipram binding activity and their relationship to emetic behavior in the ferret
    • 3H]rolipram binding activity and their relationship to emetic behavior in the ferret. J. Med. Chem. 39:1996;120-125.
    • (1996) J. Med. Chem. , vol.39 , pp. 120-125
    • Duplantier, A.J.1
  • 53
    • 0033597139 scopus 로고    scopus 로고
    • Association with the SRC family tyrosyl kinase LYN triggers a conformational change in the catalytic region of human cAMP-specific phosphodiesterase HSPDE4A4B. Consequences for rolipram inhibition
    • McPhee I., et al. Association with the SRC family tyrosyl kinase LYN triggers a conformational change in the catalytic region of human cAMP-specific phosphodiesterase HSPDE4A4B. Consequences for rolipram inhibition. J. Biol. Chem. 274:1999;11796-11810.
    • (1999) J. Biol. Chem. , vol.274 , pp. 11796-11810
    • McPhee, I.1
  • 54
    • 0033591233 scopus 로고    scopus 로고
    • The RACK1 signaling scaffold protein selectively interacts with the cAMP-specific phosphodiesterase PDE4D5
    • Yarwood S.J., et al. the RACK1 signaling scaffold protein selectively interacts with the cAMP-specific phosphodiesterase PDE4D5. J. Biol. Chem. 274:1999;14909-14917.
    • (1999) J. Biol. Chem. , vol.274 , pp. 14909-14917
    • Yarwood, S.J.1
  • 55
    • 0035901502 scopus 로고    scopus 로고
    • MAKAP assembles a protein kinase A/PDE4 phosphodiesterase cAMP signaling module
    • Dodge K.L., et al. mAKAP assembles a protein kinase A/PDE4 phosphodiesterase cAMP signaling module. EMBO J. 20:2001;1921-1930.
    • (2001) EMBO J. , vol.20 , pp. 1921-1930
    • Dodge, K.L.1
  • 56
    • 0037443097 scopus 로고    scopus 로고
    • PDE4 cAMP phosphodiesterases: Modular enzymes that orchestrate signaling cross-talk, desensitization and compartmentalization
    • Houslay M.D., Adams D.R. PDE4 cAMP phosphodiesterases: modular enzymes that orchestrate signaling cross-talk, desensitization and compartmentalization. Biochem. J. 370:2003;1-18.
    • (2003) Biochem. J. , vol.370 , pp. 1-18
    • Houslay, M.D.1    Adams, D.R.2
  • 57
    • 0141742426 scopus 로고    scopus 로고
    • Antidepressant-induced increase in high-affinity rolipram binding sites in rat brain: Dependence on noradrenergic and serotonergic function
    • Zhao Y., et al. Antidepressant-induced increase in high-affinity rolipram binding sites in rat brain: dependence on noradrenergic and serotonergic function. J. Pharmacol. Exp. Ther. 307:2003;246-253.
    • (2003) J. Pharmacol. Exp. Ther. , vol.307 , pp. 246-253
    • Zhao, Y.1
  • 58
    • 0034625541 scopus 로고    scopus 로고
    • Atomic structure of PDE4: Insights into phosphodiesterase mechanism and specificity
    • Xu R.X., et al. Atomic structure of PDE4: insights into phosphodiesterase mechanism and specificity. Science. 288:2000;1822-1825.
    • (2000) Science , vol.288 , pp. 1822-1825
    • Xu, R.X.1
  • 59
    • 0041321268 scopus 로고    scopus 로고
    • Structure of the catalytic domain of human phosphodiesterase 5 with bound drug molecules
    • Sung B.J., et al. Structure of the catalytic domain of human phosphodiesterase 5 with bound drug molecules. Nature. 425:2003;98-102.
    • (2003) Nature , vol.425 , pp. 98-102
    • Sung, B.J.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.