Identification of cyclic AMP phosphodiesterases 3, 4 and 7 in human CD4+ and CD8+ T-lymphocytes: Role in regulating proliferation and the biosynthesis of interleukin-2

British Journal of Pharmacology

Volumn 118, Issue 8, 1996, Pages 1945-1958

  Giembycz, Mark A ^a   Corrigan, Christopher J ^a   Seybold, Joachim ^a   Newton, Robert ^a   Barnes, Peter J ^a  

^a NATIONAL HEART AND LUNG INSTITUTE   (United Kingdom)

Author keywords

CD4+ T lymphocytes; CD8+ T lymphocytes; Interleukin 2 generation; Phosphodiesterase 3; Phosphodiesterase 4; Phosphodiesterase 7; Phosphodiesterase inhibitors; Proliferation

Indexed keywords

CD4 ANTIGEN; CD8 ANTIGEN; COMPLEMENTARY DNA; CYCLIC AMP; CYCLIC AMP PHOSPHODIESTERASE; GAMMA INTERFERON; INTERLEUKIN 2; IONOMYCIN; ISOENZYME; PHORBOL 13 ACETATE 12 MYRISTATE; PHOSPHODIESTERASE INHIBITOR; ROLIPRAM;

ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; DNA SEQUENCE; ENZYME ANALYSIS; ENZYME KINETICS; HUMAN; HUMAN CELL; HYDROLYSIS; LYMPHOCYTE PROLIFERATION; MITOGENESIS; NORMAL HUMAN; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; T LYMPHOCYTE;

EID: 0029833842     PISSN: 00071188     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1476-5381.1996.tb15629.x     Document Type: Article

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