Adenovirus-Mediated Delivery and Expression of a cAMP-Dependent Protein Kinase Inhibitor Gene to BEAS-2B Epithelial Cells Abolishes the Anti-Inflammatory Effects of Rolipram, Salbutamol, and Prostaglandin E 2: A Comparison with H-89

Journal of Pharmacology and Experimental Therapeutics

Volumn 309, Issue 2, 2004, Pages 833-844

  Meja, Koremu K ^a   Catley, Matthew C ^a   Cambridge, Lisa M ^a   Barnes, Peter J ^a   Lum, Hazel ^b   Newton, Robert ^c   Giembycz, Mark A ^d  

^a NATIONAL HEART AND LUNG INSTITUTE   (United Kingdom)

^b RUSH UNIVERSITY MEDICAL CENTER   (United States)

^c UNIVERSITY OF WARWICK   (United Kingdom)

^d UNIVERSITY OF CALGARY   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

8 BROMO CYCLIC AMP; ADENOVIRUS VECTOR; ARACHIDONIC ACID; CYCLIC AMP DEPENDENT PROTEIN KINASE INHIBITOR; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; INTERLEUKIN 1BETA; LUCIFERASE; MONOCYTE CHEMOTACTIC PROTEIN 1; N [2 (4 BROMOCINNAMYLAMINO)ETHYL] 5 ISOQUINOLINESULFONAMIDE; PROSTAGLANDIN E2; ROLIPRAM; SALBUTAMOL;

ANIMAL CELL; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CATALYSIS; CELL STRAIN; CELL STRAIN BEAS 2B; CYCLIC AMP RESPONSIVE ELEMENT; DRUG EFFECT; DRUG MECHANISM; ENZYME ACTIVITY; EPITHELIUM CELL; GENE DELIVERY SYSTEM; GENE EXPRESSION REGULATION; GENE TRANSFER; MYRISTYLATION; NEUROTRANSMITTER RELEASE; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; VIRUS INFECTION;

ACTIVATING TRANSCRIPTION FACTOR 1; ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ADENOSINE MONOPHOSPHATE; ADENOVIRIDAE; ALBUTEROL; ANIMALS; ARACHIDONIC ACID; CARRIER PROTEINS; CELLS, CULTURED; CYCLIC AMP RESPONSE ELEMENT-BINDING PROTEIN; CYCLIC AMP-DEPENDENT PROTEIN KINASES; DINOPROSTONE; DNA-BINDING PROTEINS; DRUG INTERACTIONS; EPITHELIAL CELLS; GENE EXPRESSION REGULATION; GENE TRANSFER TECHNIQUES; GRANULOCYTE-MACROPHAGE COLONY-STIMULATING FACTOR; HUMANS; ISOQUINOLINES; PHOSPHORYLATION; RABBITS; ROLIPRAM; SULFONAMIDES; TRANSCRIPTION FACTORS; TRITIUM;

EID: 2142650641     PISSN: 00223565     EISSN: None     Source Type: Journal    
DOI: 10.1124/jpet.103.060020     Document Type: Article

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