PDE4 inhibition and a corticosteroid in chronically antigen exposed conscious guinea-pigs

Clinical and Experimental Allergy

Volumn 28, Issue 4, 1998, Pages 513-522

  Danahay, H ^a   Broadley, K J ^a  

^a CARDIFF UNIVERSITY   (United Kingdom)

Author keywords

Airway leucocyte influx; Conscious guinea pigs; Early and late phases; Hyperreactivity; Multiple antigen challenges

Indexed keywords

15 HYDROXY 11ALPHA,9ALPHA EPOXYMETHANOPROSTA 5,13 DIENOIC ACID; 4 (3 BUTOXY 4 METHOXYBENZYL) 2 IMIDAZOLIDINONE; CORTICOSTEROID; DEXAMETHASONE; OVALBUMIN; PHOSPHODIESTERASE IV INHIBITOR;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BRONCHOSPASM; BRONCHUS HYPERREACTIVITY; CELL INFILTRATION; CHRONIC INFLAMMATION; CONTROLLED STUDY; DOSE TIME EFFECT RELATION; ENZYME INHIBITION; GUINEA PIG; INHIBITION KINETICS; INTRAPERITONEAL DRUG ADMINISTRATION; LEUKOCYTE; LUNG LAVAGE; MALE; NONHUMAN; PRIORITY JOURNAL; RESPIRATORY TRACT INFECTION;

15-HYDROXY-11 ALPHA,9 ALPHA-(EPOXYMETHANO)PROSTA-5,13-DIENOIC ACID; 3',5'-CYCLIC-NUCLEOTIDE PHOSPHODIESTERASE; 4-(3-BUTOXY-4-METHOXYBENZYL)-2-IMIDAZOLIDINONE; ADMINISTRATION, INHALATION; ANIMALS; ANTIGENS; BRONCHIAL HYPERREACTIVITY; CELL COUNT; DEXAMETHASONE; DOSE-RESPONSE RELATIONSHIP, DRUG; DOSE-RESPONSE RELATIONSHIP, IMMUNOLOGIC; EOSINOPHILIA; EOSINOPHILS; GLUCOCORTICOIDS; GUINEA PIGS; INFLAMMATION; MACROPHAGES; MALE; NEUTROPHILS; OVALBUMIN; PHOSPHODIESTERASE INHIBITORS; VASOCONSTRICTOR AGENTS;

EID: 0031950276     PISSN: 09547894     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2222.1998.00266.x     Document Type: Article

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