-
1
-
-
0035804276
-
Allergy and allergic diseases. First of two parts
-
Kay, A. B. Allergy and allergic diseases. First of two parts. N. Engl. J. Med. 344, 30-37 (2001).
-
(2001)
N. Engl. J. Med.
, vol.344
, pp. 30-37
-
-
Kay, A.B.1
-
2
-
-
0242690217
-
New targets for allergic rhinitis - A disease of civilization
-
Holgate, S. T. & Broide, D. New targets for allergic rhinitis - a disease of civilization. Nature Rev. Drug Discov. 2, 902-914 (2003).
-
(2003)
Nature Rev. Drug Discov.
, vol.2
, pp. 902-914
-
-
Holgate, S.T.1
Broide, D.2
-
3
-
-
0032565364
-
Worldwide variation in prevalence of symptoms of asthma, allergic rhinoconjunctivis, and atopic eczema: ISAAC
-
The International Study of Asthma and Allergies in Childhood (ISAAC) Steering Committee. Worldwide variation in prevalence of symptoms of asthma, allergic rhinoconjunctivis, and atopic eczema: ISAAC. Lancet 351, 1225-1232 (1998).
-
(1998)
Lancet
, vol.351
, pp. 1225-1232
-
-
-
4
-
-
0030951698
-
The distribution of total and specific serum IgE in the European Community Respiratory Health Survey
-
Burney, P. et al. The distribution of total and specific serum IgE in the European Community Respiratory Health Survey. J. Allergy Clin. Immunol. 99, 314-322 (1997).
-
(1997)
J. Allergy Clin. Immunol.
, vol.99
, pp. 314-322
-
-
Burney, P.1
-
5
-
-
0034441878
-
H2 cytokines in allergic disease
-
H2 cytokines in allergic disease. Br. Med. Bull. 56, 956-968 (2000).
-
(2000)
Br. Med. Bull.
, vol.56
, pp. 956-968
-
-
Robinson, D.S.1
-
6
-
-
6044239102
-
Making sense of asthma genes
-
Cookson, W. & Moffatt, M. Making sense of asthma genes. N. Engl. J. Med. 351, 1794-1796 (2004).
-
(2004)
N. Engl. J. Med.
, vol.351
, pp. 1794-1796
-
-
Cookson, W.1
Moffatt, M.2
-
7
-
-
0035495857
-
The germless theory of allergic disease: Revisiting the hygiene hypothesis
-
Wills-Karp, M., Santeliz, J. & Karp, C. L. The germless theory of allergic disease: revisiting the hygiene hypothesis. Nature Rev. Immunol. 1, 69-75 (2001).
-
(2001)
Nature Rev. Immunol.
, vol.1
, pp. 69-75
-
-
Wills-Karp, M.1
Santeliz, J.2
Karp, C.L.3
-
8
-
-
0024353079
-
H2 cells: Different patterns of lymphokine secretion lead to different functional properties
-
H2 cells: different patterns of lymphokine secretion lead to different functional properties. Annu. Rev. Immunol. 7, 145-173 (1989).
-
(1989)
Annu. Rev. Immunol.
, vol.7
, pp. 145-173
-
-
Mosmann, T.R.1
Coffman, R.L.2
-
9
-
-
0028593518
-
Regulation of the development of type 2 T-helper cells in allergy
-
Romagnani, S. Regulation of the development of type 2 T-helper cells in allergy. Curr. Opin. Immunol. 6, 838-846 (1994).
-
(1994)
Curr. Opin. Immunol.
, vol.6
, pp. 838-846
-
-
Romagnani, S.1
-
10
-
-
0026610142
-
H2-like bronchoalveolar T-lymphocyte population in atopic asthma
-
H2-cytokine-mRNA-positive T cells in the lungs of patients with allergic asthma.
-
(1992)
N. Engl. J. Med.
, vol.326
, pp. 298-304
-
-
Robinson, D.S.1
-
11
-
-
0027342879
-
Increases in activated T lymphocytes, eosinophis, and cytokine mRNA expression for interleukin-5 and granulocyte/macrophage colony-stimulating factor in bronchial biopsies after allergen inhalation challenge in atopic asthmatics
-
Bentley, A. M. et al. Increases in activated T lymphocytes, eosinophis, and cytokine mRNA expression for interleukin-5 and granulocyte/macrophage colony-stimulating factor in bronchial biopsies after allergen inhalation challenge in atopic asthmatics. Am. J. Respir. Cell Mol. Biol. 8, 35-42 (1993).
-
(1993)
Am. J. Respir. Cell Mol. Biol.
, vol.8
, pp. 35-42
-
-
Bentley, A.M.1
-
12
-
-
0035222530
-
Mouse models of allergic airway disease
-
Lloyd, C. M., Gonzalo, J. A., Coyle, A. J. & Gutierrez-Ramos, J. C. Mouse models of allergic airway disease. Adv. Immunol. 77, 263-295 (2001).
-
(2001)
Adv. Immunol.
, vol.77
, pp. 263-295
-
-
Lloyd, C.M.1
Gonzalo, J.A.2
Coyle, A.J.3
Gutierrez-Ramos, J.C.4
-
13
-
-
0031039796
-
Current therapies for asthma. Promise and limitations
-
Barnes, P. J. Current therapies for asthma. Promise and limitations. Chest 111, 17S-26S (1997).
-
(1997)
Chest
, vol.111
-
-
Barnes, P.J.1
-
14
-
-
0035554676
-
Regulatory T cells in the control of immune pathology
-
Maloy, K. J. & Powrie, F. Regulatory T cells in the control of immune pathology. Nature Immunol. 2, 816-822 (2001).
-
(2001)
Nature Immunol.
, vol.2
, pp. 816-822
-
-
Maloy, K.J.1
Powrie, F.2
-
15
-
-
2442484053
-
+ regulatory T cells for immunologic self-tolerance and negative control of immune responses
-
+ regulatory T cells for immunologic self-tolerance and negative control of immune responses. Annu. Rev. Immunol. 22, 531-562 (2004).
-
(2004)
Annu. Rev. Immunol.
, vol.22
, pp. 531-562
-
-
Sakaguchi, S.1
-
16
-
-
4043052238
-
Regulatory T cells and mechanisms of immune system control
-
O'Garra, A. & Vieira, P. Regulatory T cells and mechanisms of immune system control. Nature Med. 10, 801-805 (2004).
-
(2004)
Nature Med.
, vol.10
, pp. 801-805
-
-
O'Garra, A.1
Vieira, P.2
-
17
-
-
0036597371
-
+ suppressor T cells: More questions than answers
-
+ suppressor T cells: more questions than answers. Nature Rev. Immunol. 2, 389-400 (2004). References 14-17 are key reviews that describe naturally occurring and antigen-driven regulatory T cells, and they refer to the important original papers in this field.
-
(2004)
Nature Rev. Immunol.
, vol.2
, pp. 389-400
-
-
Shevach, E.1
-
18
-
-
0035284804
-
+ T cells regulate the expansion of peripheral CD4 T cells through the production of IL-10
-
+ T cells regulate the expansion of peripheral CD4 T cells through the production of IL-10. J. Immunol. 166, 3008-3018 (2001).
-
(2001)
J. Immunol.
, vol.166
, pp. 3008-3018
-
-
Annacker, O.1
-
19
-
-
0037243827
-
R cells suppress innate immune pathology through cytokine-dependent mechanisms
-
R cells suppress innate immune pathology through cytokine-dependent mechanisms. J. Exp. Med. 197, 111-119 (2003).
-
(2003)
J. Exp. Med.
, vol.197
, pp. 111-119
-
-
Maloy, K.J.1
-
20
-
-
0035320679
-
+ regulatory T cells induced by an agonist self-peptide
-
+ regulatory T cells induced by an agonist self-peptide. Nature Immunol. 2, 301-306 (2001).
-
(2001)
Nature Immunol.
, vol.2
, pp. 301-306
-
-
Jordan, M.S.1
-
21
-
-
2542420993
-
In vivo instruction of suppressor commitment in naive T cells
-
Apostolou, I. & Von Boehmer, H. In vivo instruction of suppressor commitment in naive T cells. J. Exp. Med. 199, 1401-1408 (2004).
-
(2004)
J. Exp. Med.
, vol.199
, pp. 1401-1408
-
-
Apostolou, I.1
Von Boehmer, H.2
-
23
-
-
0035180065
-
+ regulatory T cells: Their common role in controlling autoimmunity, tumor immunity, and transplantation tolerance
-
+ regulatory T cells: their common role in controlling autoimmunity, tumor immunity, and transplantation tolerance. Immunol. Res. 182, 18-32 (2001).
-
(2001)
Immunol. Res.
, vol.182
, pp. 18-32
-
-
Sakaguchi, S.1
-
24
-
-
0034679567
-
+ regulatory cells that control intestinal inflammation
-
+ regulatory cells that control intestinal inflammation. J. Exp. Med. 192, 295-302 (2000).
-
(2000)
J. Exp. Med.
, vol.192
, pp. 295-302
-
-
Read, S.1
Malmstrom, V.2
Powrie, F.3
-
25
-
-
0034679560
-
+ regulatory T cells constitutively expressing cytotoxic T lymphocyte-associated antigen 4
-
+ regulatory T cells constitutively expressing cytotoxic T lymphocyte-associated antigen 4. J. Exp. Med. 192, 303-310 (2000).
-
(2000)
J. Exp. Med.
, vol.192
, pp. 303-310
-
-
Takahashi, T.1
-
27
-
-
0036195161
-
+ immunoregulatory T cells: Gene expression analysis reveals a functional role for the glucocorticoid-induced TNF receptor
-
+ immunoregulatory T cells: gene expression analysis reveals a functional role for the glucocorticoid-induced TNF receptor. Immunity 16, 311-323 (2002).
-
(2002)
Immunity
, vol.16
, pp. 311-323
-
-
McHugh, R.S.1
-
29
-
-
0033523607
-
An essential role for interleukin 10 in the function of regulatory T cells that inhibit intestinal inflammation
-
Asseman, C., Mauze, S., Leach, M. W., Coffman, R. L. & Powrie, F. An essential role for interleukin 10 in the function of regulatory T cells that inhibit intestinal inflammation. J. Exp. Med. 190, 995-1004 (1999).
-
(1999)
J. Exp. Med.
, vol.190
, pp. 995-1004
-
-
Asseman, C.1
Mauze, S.2
Leach, M.W.3
Coffman, R.L.4
Powrie, F.5
-
32
-
-
0347785480
-
Control of regulatory T cell development by the transcription factor Foxp3
-
Hori, S., Nomura, T. & Sakaguchi, S. Control of regulatory T cell development by the transcription factor Foxp3. Science 299, 1057-1061 (2003).
-
(2003)
Science
, vol.299
, pp. 1057-1061
-
-
Hori, S.1
Nomura, T.2
Sakaguchi, S.3
-
35
-
-
0041931076
-
Foxp3 and natural regulatory T cells: Key to a cell lineage?
-
Ramsdell, F. Foxp3 and natural regulatory T cells: key to a cell lineage? Immunity 19, 165-168 (2003).
-
(2003)
Immunity
, vol.19
, pp. 165-168
-
-
Ramsdell, F.1
-
36
-
-
8344275995
-
+ regulatory T cells
-
+ regulatory T cells. Int. Immunol. 16, 1643-1656 (2004).
-
(2004)
Int. Immunol.
, vol.16
, pp. 1643-1656
-
-
Yagi, H.1
-
37
-
-
0348223787
-
+ regulatory T cells by TGF-β induction of transcription factor Foxp3
-
+ regulatory T cells by TGF-β induction of transcription factor Foxp3. J. Exp. Med. 198, 1875-1886 (2003).
-
(2003)
J. Exp. Med.
, vol.198
, pp. 1875-1886
-
-
Chen, W.1
-
39
-
-
0028519015
-
+ T cells
-
+ T cells. Immunity 1, 553-562 (1994).
-
(1994)
Immunity
, vol.1
, pp. 553-562
-
-
Powrie, F.1
-
40
-
-
0242580070
-
+ regulatory T cells cure murine colitis: The role of IL-10, TGF-β, and CTLA4
-
+ regulatory T cells cure murine colitis: the role of IL-10, TGF-β, and CTLA4. J. Immunol. 171, 5012-5017 (2003).
-
(2003)
J. Immunol.
, vol.171
, pp. 5012-5017
-
-
Liu, H.1
Hu, B.2
Xu, D.3
Liew, F.Y.4
-
41
-
-
0033682056
-
+ immunoregulatory T cells that control autoimmune diabetes
-
+ immunoregulatory T cells that control autoimmune diabetes. Immunity 12, 431-440 (2000).
-
(2000)
Immunity
, vol.12
, pp. 431-440
-
-
Salomon, B.1
-
42
-
-
0035869432
-
IL-10 is required for regulatory T cells to mediate tolerance to alloantigens in vivo
-
Hara, M. et al. IL-10 is required for regulatory T cells to mediate tolerance to alloantigens in vivo. J. Immunol. 166, 3789-3796 (2001).
-
(2001)
J. Immunol.
, vol.166
, pp. 3789-3796
-
-
Hara, M.1
-
43
-
-
0036467522
-
+ regulatory T cells prevent graft rejection: CTLA-4- and IL-10-dependent immunoregulation of alloresponses
-
+ regulatory T cells prevent graft rejection: CTLA-4- and IL-10-dependent immunoregulation of alloresponses. J. Immunol. 166, 1080-1086 (2002).
-
(2002)
J. Immunol.
, vol.166
, pp. 1080-1086
-
-
Kingsley, C.I.1
Karim, M.2
Bushell, A.R.3
Wood, K.J.4
-
44
-
-
0033571105
-
+ T cells: A common basis between tumor immunity and autoimmunity
-
+ T cells: a common basis between tumor immunity and autoimmunity. J. Immunol. 163, 5211-5218 (1999).
-
(1999)
J. Immunol.
, vol.163
, pp. 5211-5218
-
-
Shimizu, J.1
Yamazaki, S.2
Sakaguchi, S.3
-
46
-
-
0037220923
-
H2 cells, Leishmania major infection, and colitis in mice
-
H2 cells, Leishmania major infection, and colitis in mice. J. Immunol. 170, 394-399 (2003).
-
(2003)
J. Immunol.
, vol.170
, pp. 394-399
-
-
Xu, D.1
-
47
-
-
2942709797
-
H2 cells
-
H2 cells. J. Immunol. 173, 267-274 (2004).
-
(2004)
J. Immunol.
, vol.173
, pp. 267-274
-
-
Stassen, M.1
-
48
-
-
3543098686
-
+ HIV-specifc T cell immune responses in vitro and are associated with favorable clinical markers of disease status
-
+ HIV-specifc T cell immune responses in vitro and are associated with favorable clinical markers of disease status. J. Exp. Med. 200, 331-343 (2004).
-
(2004)
J. Exp. Med.
, vol.200
, pp. 331-343
-
-
Kinter, A.L.1
-
50
-
-
19344374571
-
HIV infection of naturally occurring and genetically reprogrammed human regulatory T-cells
-
Oswald-Richter, K. et al. HIV infection of naturally occurring and genetically reprogrammed human regulatory T-cells. PLoS Biol. 2, E198 (2004).
-
(2004)
PLoS Biol.
, vol.2
-
-
Oswald-Richter, K.1
-
51
-
-
0037514382
-
Lung CD25 CD4 regulatory T cells suppress type 2 immune responses but not bronchial hyperreactivity
-
Hadeiba, H. & Locksley, R. M. Lung CD25 CD4 regulatory T cells suppress type 2 immune responses but not bronchial hyperreactivity. J. Immunol. 170, 5502-5510 (2003).
-
(2003)
J. Immunol.
, vol.170
, pp. 5502-5510
-
-
Hadeiba, H.1
Locksley, R.M.2
-
53
-
-
1342308180
-
+ regulatory T-cell suppression of allergen-driven T-cell activation to atopic status and expression of allergic disease
-
H2 responses occurs in healthy, non-atopic individuals.
-
(2004)
Lancet
, vol.363
, pp. 608-615
-
-
Ling, E.M.1
-
55
-
-
0031739410
-
+ T cells: A population of T cells with immune regulatory activities in vitro
-
+ T cells: a population of T cells with immune regulatory activities in vitro. Eur. J. Immunol. 28, 3435-3447 (1998).
-
(1998)
Eur. J. Immunol.
, vol.28
, pp. 3435-3447
-
-
Read, S.1
-
57
-
-
0030636560
-
Immunoregulatory role of IL-10 during superantigen-induced hyporesponsiveness in vivo
-
Sundstedt, A. et al. Immunoregulatory role of IL-10 during superantigen-induced hyporesponsiveness in vivo. J. Immunol. 158, 180-186 (1997).
-
(1997)
J. Immunol.
, vol.158
, pp. 180-186
-
-
Sundstedt, A.1
-
58
-
-
0037310355
-
Role for IL-10 in suppression mediated by peptide-induced regulatory T cells in vivo
-
Sundstedt, A., O'Neill, E. J., Nicolson, K. S. & Wraith, D. C. Role for IL-10 in suppression mediated by peptide-induced regulatory T cells in vivo. J. Immunol. 170, 1240-1248 (2003).
-
(2003)
J. Immunol.
, vol.170
, pp. 1240-1248
-
-
Sundstedt, A.1
O'Neill, E.J.2
Nicolson, K.S.3
Wraith, D.C.4
-
59
-
-
0030704726
-
+ T-cell population, which inhibits antigen-specific T-cell responses
-
+ T-cell population, which inhibits antigen-specific T-cell responses. Nature 389, 737-742 (1997).
-
(1997)
Nature
, vol.389
, pp. 737-742
-
-
Groux, H.1
-
60
-
-
0035339884
-
IFN-α and IL-10 induce the differentiation of human type 1T regulatory cells
-
Levings, M. K. et al. IFN-α and IL-10 induce the differentiation of human type 1 T regulatory cells. J. Immunol. 166, 5530-5539 (2001).
-
(2001)
J. Immunol.
, vol.166
, pp. 5530-5539
-
-
Levings, M.K.1
-
61
-
-
0031964338
-
Interleukin 10 secretion and impaired effector function of major histocompatibility complex class II-restricted T cells anergized in vivo
-
Buer, J. et al. Interleukin 10 secretion and impaired effector function of major histocompatibility complex class II-restricted T cells anergized in vivo. J. Exp. Med. 187, 177-183 (1998).
-
(1998)
J. Exp. Med.
, vol.187
, pp. 177-183
-
-
Buer, J.1
-
62
-
-
0037018104
-
H2-inducing cytokines
-
H2 cytokines, which has implications for immunotherapy.
-
(2002)
J. Exp. Med.
, vol.195
, pp. 603-616
-
-
Barrat, F.J.1
-
63
-
-
0036165718
-
+ regulatory T cells control the burst of superantigen-induced cytokine production: The role of IL-10
-
+ regulatory T cells control the burst of superantigen-induced cytokine production: the role of IL-10. Int. Immunol. 14, 233-239 (2002).
-
(2002)
Int. Immunol.
, vol.14
, pp. 233-239
-
-
Pontoux, C.1
Banz, A.2
Papiernik, M.3
-
64
-
-
0035186416
-
H3 regulatory cells
-
H3 regulatory cells. Immunol. Rev. 182, 207-214 (2001).
-
(2001)
Immunol. Rev.
, vol.182
, pp. 207-214
-
-
Weiner, H.L.1
-
65
-
-
0347895101
-
+ cells with CD3 and CD46 induces a T-regulatory cell 1 phenotype
-
+ cells with CD3 and CD46 induces a T-regulatory cell 1 phenotype. Nature 421, 388-392 (2003).
-
(2003)
Nature
, vol.421
, pp. 388-392
-
-
Kemper, C.1
-
66
-
-
0028158319
-
High levels of interleukin 10 production in vivo are associated with tolerance in SCID patients transplanted with HLA mismatched hematopoietic stem cells
-
Bacchetta, R. et al. High levels of interleukin 10 production in vivo are associated with tolerance in SCID patients transplanted with HLA mismatched hematopoietic stem cells. J. Exp. Med. 179, 493-502 (1994). This is an important early study that describes that high endogenous IL-10 production is a general phenomenon in patients with SCID in whom allogeneic haematopoietic stem-cell transplantation results in immunological reconstitution and induction of tolerance. This has been a seminal paper in the current resurgence of interest in the therapeutic applications of regulatory T cells.
-
(1994)
J. Exp. Med.
, vol.179
, pp. 493-502
-
-
Bacchetta, R.1
-
67
-
-
0034613767
-
+ T cells with regulatory properties by repetitive stimulation with allogeneic immature human dendritic cells
-
+ T cells with regulatory properties by repetitive stimulation with allogeneic immature human dendritic cells. J. Exp. Med. 192, 1213-1222 (2000).
-
(2000)
J. Exp. Med.
, vol.192
, pp. 1213-1222
-
-
Jonuleit, H.1
Schmitt, E.2
Schuler, G.3
Knop, J.4
Enk, A.H.5
-
69
-
-
0033526853
-
Anergy and cytokine-mediated suppression as distinct superantigen-induced tolerance mechanisms in vivo
-
Miller, C., Ragheb, J. A. & Schwartz, R. H. Anergy and cytokine-mediated suppression as distinct superantigen-induced tolerance mechanisms in vivo. J. Exp. Med. 190, 53-64 (1999).
-
(1999)
J. Exp. Med.
, vol.190
, pp. 53-64
-
-
Miller, C.1
Ragheb, J.A.2
Schwartz, R.H.3
-
70
-
-
2442450433
-
+ regulatory T cells
-
Reg cells, do not express FOXP3, but both populations nave a comparable ability to inhibit the proliferation of naive T cells.
-
(2004)
J. Immunol.
, vol.172
, pp. 5986-5993
-
-
Vieira, P.L.1
-
71
-
-
0032128421
-
Role of interleukin 10 in specific immunotherapy
-
Akdis, C. A., Blesken, T., Akdis, M., Wuthrich, B. & Blaser, K. Role of interleukin 10 in specific immunotherapy. J. Clin. Invest 102, 98-106 (1998). This is a comprehensive early study that shows the association of IL-10 production with tolerance to allergen. The authors provide evidence for EL-10 production in response to allergen following successful allergen immunotherapy of bee-keepers who had become tolerant following repeated stings and of non-atopic individuals.
-
(1998)
J. Clin. Invest.
, vol.102
, pp. 98-106
-
-
Akdis, C.A.1
Blesken, T.2
Akdis, M.3
Wuthrich, B.4
Blaser, K.5
-
72
-
-
0034890907
-
Pulmonary dendritic cells producing IL-10 mediate tolerance induced by respiratory exposure to antigen
-
Akbari, O., DeKruyff, R. H. & Umetsu, D. T. Pulmonary dendritic cells producing IL-10 mediate tolerance induced by respiratory exposure to antigen. Nature Immunol. 2, 725-731 (2001).
-
(2001)
Nature Immunol.
, vol.2
, pp. 725-731
-
-
Akbari, O.1
DeKruyff, R.H.2
Umetsu, D.T.3
-
73
-
-
0036732461
-
Antigen-specific regulatory T cells develop via the ICOS-ICOS-ligand pathway and inhibit allergen-induced airway hyperreactivity
-
Akbari, O. et al. Antigen-specific regulatory T cells develop via the ICOS-ICOS-ligand pathway and inhibit allergen-induced airway hyperreactivity. Nature Med. 8, 1024-1032 (2002). References 72 and 73 are studies from the same research group that identify pulmonary DCs and T cells as important sources of IL-10 in the lungs and identify the role of IL-10 in the induction of respiratory tolerance.
-
(2002)
Nature Med.
, vol.8
, pp. 1024-1032
-
-
Akbari, O.1
-
74
-
-
12944310982
-
IL-10-producing T cells suppress immune responses in anergic tuberculosis patients
-
Boussiotis, V. A. et al. IL-10-producing T cells suppress immune responses in anergic tuberculosis patients. J. Clin. Invest. 105, 1317-1325 (2000).
-
(2000)
J. Clin. Invest.
, vol.105
, pp. 1317-1325
-
-
Boussiotis, V.A.1
-
75
-
-
0032872122
-
+ T cell clones producing both interferon-γ and interleukin-10 predominate in bronchoateolar lavages of active pulmonary tuberculosis patients
-
+ T cell clones producing both interferon-γ and interleukin-10 predominate in bronchoateolar lavages of active pulmonary tuberculosis patients. Clin. Immunol. 92, 224-234 (1999).
-
(1999)
Clin. Immunol.
, vol.92
, pp. 224-234
-
-
Gerosa, F.1
-
76
-
-
0035914926
-
Regulatory role of T cells producing both interferon γ and interleukin 10 in persistent infection
-
Trinchieri, G. Regulatory role of T cells producing both interferon γ and interleukin 10 in persistent infection. J. Exp. Med. 194, F53-F57 (2001).
-
(2001)
J. Exp. Med.
, vol.194
-
-
Trinchieri, G.1
-
77
-
-
0037136284
-
+ T regulatory cells suppress Helicobacter hepaticus-induced colitis
-
+ T regulatory cells suppress Helicobacter hepaticus-induced colitis. J. Exp. Med. 196, 505-515 (2002).
-
(2002)
J. Exp. Med.
, vol.196
, pp. 505-515
-
-
Kullberg, M.C.1
-
78
-
-
0037436119
-
+ T cell-mediated suppression by dendritic cells
-
+ T cell-mediated suppression by dendritic cells. Science 299, 1033-1036 (2003).
-
(2003)
Science
, vol.299
, pp. 1033-1036
-
-
Pasare, C.1
Medzhitov, R.2
-
79
-
-
2942685507
-
Immune responses in healthy and allergic individuals are characterized by a fine balance between allergen-specific T regulatory 1 and T helper 2 cells
-
Akdis, M. et al. Immune responses in healthy and allergic individuals are characterized by a fine balance between allergen-specific T regulatory 1 and T helper 2 cells. J. Exp. Med. 199, 1567-1575 (2004). This is a recent study showing that IL-10-secreting regulatory T cells are the dominant cell subset that is specific for common environmental allergens in healthy individuals, whereas there is a high frequency of allergen-specific IL-4-secreting T cells in allergic individuals.
-
(2004)
J. Exp. Med.
, vol.199
, pp. 1567-1575
-
-
Akdis, M.1
-
80
-
-
17144419991
-
Correction of the defect in glucocorticoid-induced IL-10 synthesis in T cells from glucocorticoid resistant asthmatic patients
-
3 and IL-10 can restore the reactivity of T cells from steroid-resistant patients to glucocorticoids and thereby induce IL-10 synthesis.
-
(2004)
J. Allergy Clin. Immunol.
, vol.113
, Issue.SUPPL.
-
-
Hawrylowicz, C.1
-
83
-
-
0035167967
-
The immune dysregulation, potyendocrinopathy, enteropathy, X-linked syndrome (IPEX) is caused by mutations of FOXP3
-
Bennett, C. L. et al. The immune dysregulation, potyendocrinopathy, enteropathy, X-linked syndrome (IPEX) is caused by mutations of FOXP3. Nature Genet. 27, 20-21 (2001).
-
(2001)
Nature Genet.
, vol.27
, pp. 20-21
-
-
Bennett, C.L.1
-
84
-
-
0035163909
-
X-linked neonatal diabetes mellitus, enteropathy and endocrinopathy syndrome is the human equivalent of mouse scurfy
-
Wildin, R. S. et al. X-linked neonatal diabetes mellitus, enteropathy and endocrinopathy syndrome is the human equivalent of mouse scurfy. Nature Genet. 27, 18-20 (2001).
-
(2001)
Nature Genet.
, vol.27
, pp. 18-20
-
-
Wildin, R.S.1
-
85
-
-
0034526617
-
JM2, encoding a fork head-related protein, is mutated in X-linked autoimmunity-allergic disregulation syndrome
-
Chatila, T. A. et al. JM2, encoding a fork head-related protein, is mutated in X-linked autoimmunity-allergic disregulation syndrome. J. Clin. Invest. 106, R75-R81 (2000). References 83-85 show that mutations in the human FOXP3 gene are associated with immune dysregulation and disease.
-
(2000)
J. Clin. Invest.
, vol.106
-
-
Chatila, T.A.1
-
86
-
-
4544256262
-
H2 cytokines by CD4CD25 regulatory T cells in birch allergies during birch pollen season
-
H2 cytokines by CD4CD25 regulatory T cells in birch allergies during birch pollen season. Clin. Exp. Allergy 34, 1364-1372 (2004).
-
(2004)
Clin. Exp. Allergy
, vol.34
, pp. 1364-1372
-
-
Grindebacke, H.1
-
87
-
-
0035881129
-
+ regulatory T cells in T helper 2 cell-mediated allergic inflammation in the airways
-
+ regulatory T cells in T helper 2 cell-mediated allergic inflammation in the airways. Am. J. Respr. Crit. Care Med. 164, 680-687 (2001).
-
(2001)
Am. J. Respr. Crit. Care Med.
, vol.164
, pp. 680-687
-
-
Suto, A.1
-
89
-
-
0035158734
-
Hyper immunoglobulin E response in mice with monoclonal populations of B and T lymphocytes
-
Curotto de Lafaille, M. A. et al. Hyper immunoglobulin E response in mice with monoclonal populations of B and T lymphocytes. J. Exp. Med. 194, 1349-1359 (2001).
-
(2001)
J. Exp. Med.
, vol.194
, pp. 1349-1359
-
-
Curotto De Lafaille, M.A.1
-
90
-
-
3242754344
-
+ T cells expressing membrane-bound TGF-β and FOXP3
-
+ T cells expressing membrane-bound TGF-β and FOXP3. J. Clin. Invest. 114, 28-38 (2004).
-
(2004)
J. Clin. Invest.
, vol.114
, pp. 28-38
-
-
Ostroukhova, M.1
-
92
-
-
0035062021
-
Interleukin-10 and the interleukin-10 receptor
-
Moore, K. W., de Waal Malefyt, R., Coffman, R. L. & O'Garra, A. Interleukin-10 and the interleukin-10 receptor. Annu. Rev. Immunol. 19, 683-765 (2001). This is a comprehensive review of the biology of IL-10.
-
(2001)
Annu. Rev. Immunol.
, vol.19
, pp. 683-765
-
-
Moore, K.W.1
De Waal Malefyt, R.2
Coffman, R.L.3
O'Garra, A.4
-
94
-
-
0026000892
-
Interleukin 10 (IL-10) and viral IL-10 strongly reduce antigen-specific human T cell proliferation by diminishing the antigen-presenting capacity of monocytes via downregulation of class II major histocompatibility complex expression
-
de Waal Malefyt, R. et al. Interleukin 10 (IL-10) and viral IL-10 strongly reduce antigen-specific human T cell proliferation by diminishing the antigen-presenting capacity of monocytes via downregulation of class II major histocompatibility complex expression. J. Exp. Med. 174, 915-924 (1991).
-
(1991)
J. Exp. Med.
, vol.174
, pp. 915-924
-
-
De Waal Malefyt, R.1
-
95
-
-
0026529405
-
IL-10 inhibits parasite killing and nitrogen oxide production by IFN-γ-activated macrophages
-
Gazzinelli, R. T., Oswald, I. P., James, S. L. & Sher, A. IL-10 inhibits parasite killing and nitrogen oxide production by IFN-γ-activated macrophages. J. Immunol. 148, 1792-1796 (1992).
-
(1992)
J. Immunol.
, vol.148
, pp. 1792-1796
-
-
Gazzinelli, R.T.1
Oswald, I.P.2
James, S.L.3
Sher, A.4
-
96
-
-
0031049941
-
Interleukin-10 prevents the generation of dendritic cells from human peripheral blood mononuclear cells cultured with interleukin-4 and granulocyte/macrophage-colony-stimulating factor
-
Buelens, C. et al. Interleukin-10 prevents the generation of dendritic cells from human peripheral blood mononuclear cells cultured with interleukin-4 and granulocyte/macrophage-colony-stimulating factor. Eur. J. Immunol. 27, 756-762 (1997).
-
(1997)
Eur. J. Immunol.
, vol.27
, pp. 756-762
-
-
Buelens, C.1
-
97
-
-
0035337139
-
Reversing lipopolysaccharide toxicity by ligating the macrophage Fcγ receptors
-
Gerber, J. S. & Mosser, D. M. Reversing lipopolysaccharide toxicity by ligating the macrophage Fcγ receptors. J. Immunol. 166, 6861-6868 (2001).
-
(2001)
J. Immunol.
, vol.166
, pp. 6861-6868
-
-
Gerber, J.S.1
Mosser, D.M.2
-
98
-
-
0026094306
-
Interleukin 10 (L-10) inhibits cytokine synthesis by human monocytes: An autoregulatory role of IL-10 produced by monocytes
-
de Waal Malefyt, R., Abrams, J., Bennett, B., Figdor, C. G. & de Vries, J. E. Interleukin 10 (L-10) inhibits cytokine synthesis by human monocytes: an autoregulatory role of IL-10 produced by monocytes. J. Exp. Med. 174, 1209-1220 (1991).
-
(1991)
J. Exp. Med.
, vol.174
, pp. 1209-1220
-
-
De Waal Malefyt, R.1
Abrams, J.2
Bennett, B.3
Figdor, C.G.4
De Vries, J.E.5
-
99
-
-
0036786447
-
Microbial recognition via Toll-like receptor-dependent and -independent pathways determines the cytokine response of murine dendritric cell subsets to CD40 triggering
-
Edwards, A. D. et al. Microbial recognition via Toll-like receptor-dependent and -independent pathways determines the cytokine response of murine dendritric cell subsets to CD40 triggering. J. Immunol. 169, 3652-3660 (2002).
-
(2002)
J. Immunol.
, vol.169
, pp. 3652-3660
-
-
Edwards, A.D.1
-
100
-
-
0037148511
-
Pathogen-specific T regulatory 1 cells induced in the respiratory tract by a bacterial molecule that stimulates interleukin 10 production by dendritic cells: A novel strategy for evasion of protective T helper type 1 responses by Bordetella pertussis
-
McGuirk, P., McCann, C. & Mills, K. H. Pathogen-specific T regulatory 1 cells induced in the respiratory tract by a bacterial molecule that stimulates interleukin 10 production by dendritic cells: a novel strategy for evasion of protective T helper type 1 responses by Bordetella pertussis. J. Exp. Med. 195, 221-231 (2002).
-
(2002)
J. Exp. Med.
, vol.195
, pp. 221-231
-
-
McGuirk, P.1
McCann, C.2
Mills, K.H.3
-
101
-
-
0041652405
-
Interleukin-10 is a natural suppressor of cytokine production and inflammation in a murine model of allergic bronchopulmonary aspergillosis
-
H1, responses in vivo.
-
(1997)
J. Exp. Med.
, vol.186
, pp. 1089-1099
-
-
Grunig, G.1
-
102
-
-
0038283161
-
Interleukin-10 therapy - Review of a new approach
-
Asadullah, K. Sterry, W. & Volk, H. D. Interleukin-10 therapy - review of a new approach. Pharmacol. Rev. 55, 241-269 (2003). This is a comprehensive review of clinical studies involving IL-10.
-
(2003)
Pharmacol. Rev.
, vol.55
, pp. 241-269
-
-
Asadullah, K.1
Sterry, W.2
Volk, H.D.3
-
103
-
-
0030030857
-
Interleukin-10 inhibits cytokine generation from mast cells
-
Arock, M., Zuany-Amorim, C., Singer, M., Benhamou, M. & Pretolani, M. Interleukin-10 inhibits cytokine generation from mast cells. Eur. J. Immunol. 26, 166-70 (1996).
-
(1996)
Eur. J. Immunol.
, vol.26
, pp. 166-170
-
-
Arock, M.1
Zuany-Amorim, C.2
Singer, M.3
Benhamou, M.4
Pretolani, M.5
-
104
-
-
0034851641
-
Inhibition of IgE-induced activation of human mast cells by IL-10
-
Royer, B. et al. Inhibition of IgE-induced activation of human mast cells by IL-10. Clin. Exp. Allergy 31, 694-704 (2001).
-
(2001)
Clin. Exp. Allergy
, vol.31
, pp. 694-704
-
-
Royer, B.1
-
105
-
-
0028283903
-
Interleukin 10 inhibits lipoporysaccharide-induced survival and cytokine production by human peripheral blood eosinophils
-
H1 responses.
-
(1994)
J. Exp. Med.
, vol.180
, pp. 711-715
-
-
Takanaski, S.1
-
106
-
-
10744232817
-
Grass pollen immunotherapy induces mucosal and peripheral IL-10 responses and blocking IgG activity
-
Nouri-Aria, K. T. et al. Grass pollen immunotherapy induces mucosal and peripheral IL-10 responses and blocking IgG activity. J. Immunol. 172, 3252-3259 (2004).
-
(2004)
J. Immunol.
, vol.172
, pp. 3252-3259
-
-
Nouri-Aria, K.T.1
-
107
-
-
0032055598
-
IgE versus IgG4 production can be differentially regulated by IL-10
-
Jeannin, P., Lecoanet, S., Delneste, Y., Gauchat, J. F. & Bonnefoy, J. Y. IgE versus IgG4 production can be differentially regulated by IL-10. J. Immunol. 160, 3555-3561 (1998).
-
(1998)
J. Immunol.
, vol.160
, pp. 3555-3561
-
-
Jeannin, P.1
Lecoanet, S.2
Delneste, Y.3
Gauchat, J.F.4
Bonnefoy, J.Y.5
-
108
-
-
0029984767
-
Interleukin-10 regulation in normal subjects and patients with asthma
-
Borish, L. et al. Interleukin-10 regulation in normal subjects and patients with asthma. J. Allergy Clin. Immunol. 97, 1288-1296 (1996).
-
(1996)
J. Allergy Clin. Immunol.
, vol.97
, pp. 1288-1296
-
-
Borish, L.1
-
109
-
-
13144279268
-
Haplotype associated with low interleukin-10 production in patients with severe asthma
-
Lim, S., Crawley, E., Woo, P. & Barnes, P. J. Haplotype associated with low interleukin-10 production in patients with severe asthma. Lancet 352, 113 (1998).
-
(1998)
Lancet
, vol.352
, pp. 113
-
-
Lim, S.1
Crawley, E.2
Woo, P.3
Barnes, P.J.4
-
110
-
-
19944427405
-
An immunoepidemiological approach to asthma: Identification of in-vitro T-cell response patterns associated with different wheezing phenotypes in children
-
Heaton, T. et al. An immunoepidemiological approach to asthma: identification of in-vitro T-cell response patterns associated with different wheezing phenotypes in children. Lancer 365, 142-149 (2005). References 108-110 provide evidence for an inverse correlation of IL-10 levels with disease severity.
-
(2005)
Lancer
, vol.365
, pp. 142-149
-
-
Heaton, T.1
-
111
-
-
0033219725
-
Interleukin-10 gene transfer to the airway regulates allergic mucosal sensitization in mice
-
Stampfli, M. R. et al. Interleukin-10 gene transfer to the airway regulates allergic mucosal sensitization in mice. Am. J. Respir. Cell Mol. Biol. 21, 586-596 (1999).
-
(1999)
Am. J. Respir. Cell Mol. Biol.
, vol.21
, pp. 586-596
-
-
Stampfli, M.R.1
-
112
-
-
0036736840
-
CD4 T-helper cells engineered to produce IL-10 prevent allergen-induced airway hyperreactivity and inflammation
-
Oh, J. W. et al. CD4 T-helper cells engineered to produce IL-10 prevent allergen-induced airway hyperreactivity and inflammation. J. Alergy Clin. Immunol. 110, 460-468 (2002).
-
(2002)
J. Alergy Clin. Immunol.
, vol.110
, pp. 460-468
-
-
Oh, J.W.1
-
113
-
-
10144229329
-
Clinical, hematologic, and immunologic effects of interleukin-10 in humans
-
Fuchs, A. C. et al. Clinical, hematologic, and immunologic effects of interleukin-10 in humans. J. Clin. Immunol. 16, 291-303 (1996).
-
(1996)
J. Clin. Immunol.
, vol.16
, pp. 291-303
-
-
Fuchs, A.C.1
-
114
-
-
0031845084
-
Immunotherapy: Past and present
-
Norman, P. S. Immunotherapy: past and present. J. Allergy Clin. Immunol. 102, 1-10 (1998).
-
(1998)
J. Allergy Clin. Immunol.
, vol.102
, pp. 1-10
-
-
Norman, P.S.1
-
115
-
-
2442648797
-
Allergen immunotherapy: Therapeutic vaccines for allergic diseases
-
World Health Organization. American Academy of Allergy, Asthma and Immunology
-
Bousquet, J. et al. Allergen immunotherapy: therapeutic vaccines for allergic diseases. World Health Organization. American Academy of Allergy, Asthma and Immunology. Ann. Allergy Asthma Immunol. 81, 401-405 (1998).
-
(1998)
Ann. Allergy Asthma Immunol.
, vol.81
, pp. 401-405
-
-
Bousquet, J.1
-
116
-
-
3042840183
-
Immunotherapy: 1999-2004
-
Norman, P. S. Immunotherapy: 1999-2004. J. Allergy Clin. Immunol. 113, 1013-1023 (2004).
-
(2004)
J. Allergy Clin. Immunol.
, vol.113
, pp. 1013-1023
-
-
Norman, P.S.1
-
118
-
-
0036170801
-
Pollen immunotherapy reduces the development of asthma in children, with seasonal rhinoconjunctivitis (the PAT-study)
-
Moller, C. et al. Pollen immunotherapy reduces the development of asthma in children, with seasonal rhinoconjunctivitis (the PAT-study). J. Allergy Clin. Immunol. 109, 251-256 (2002).
-
(2002)
J. Allergy Clin. Immunol.
, vol.109
, pp. 251-256
-
-
Moller, C.1
-
119
-
-
0034847103
-
Prevention of new sensitizations in asthmatic children monosensitized to house dust mite by specific immunotherapy. A six-year follow-up study
-
Pajno, G. B., Barberio, G., DeLuca, F., Morabito, L. & Parmiani, S. Prevention of new sensitizations in asthmatic children monosensitized to house dust mite by specific immunotherapy. A six-year follow-up study. Clin. Exp. Allergy 31, 1392-1397 (2001).
-
(2001)
Clin. Exp. Allergy
, vol.31
, pp. 1392-1397
-
-
Pajno, G.B.1
Barberio, G.2
DeLuca, F.3
Morabito, L.4
Parmiani, S.5
-
120
-
-
3042706297
-
Status of immunotherapy: Current and future
-
Casale, T. B. Status of immunotherapy: current and future. J. Allergy Clin. Immunol. 113, 1036-1039 (2004).
-
(2004)
J. Allergy Clin. Immunol.
, vol.113
, pp. 1036-1039
-
-
Casale, T.B.1
-
121
-
-
0028901793
-
Bee venom immunotherapy results in decrease of IL-4 and IL-5 and increase of IFN-γ secretion in specific allergen-stimulated T cell cultures
-
H1 phenotype.
-
(1995)
J. Immunol.
, vol.154
, pp. 4187-1194
-
-
Jutel, M.1
-
122
-
-
9844266243
-
H1 in T-cell clones specific for Phlp 1, a major grass pollen allergen
-
H1 in T-cell clones specific for Phlp 1, a major grass pollen allergen. Clin. Exp. Allergy 27, 1007-1015 (1997).
-
(1997)
Clin. Exp. Allergy
, vol.27
, pp. 1007-1015
-
-
Ebner, C.1
-
123
-
-
0036164580
-
H2 cytokine ratios
-
H2 cytokine ratios. Immunology 105, 56-62 (2002).
-
(2002)
Immunology
, vol.105
, pp. 56-62
-
-
Wachholz, P.A.1
-
124
-
-
0030764472
-
Allergen induced cytokine profiles in type I allergic individuals before and after immunotherapy
-
Soderlund, A. et al. Allergen induced cytokine profiles in type I allergic individuals before and after immunotherapy. Immunol. Lett. 57, 177-181 (1997).
-
(1997)
Immunol. Lett.
, vol.57
, pp. 177-181
-
-
Soderlund, A.1
-
125
-
-
0031694702
-
Comparison between the in vitro cytokine production of mononuclear cells of young asthmatics with and without immunotherapy (IT)
-
van Bever, H. P., Vereecke, I. F., Bridts, C. H., De Clerck, L. S. & Stevens, W. J. Comparison between the in vitro cytokine production of mononuclear cells of young asthmatics with and without immunotherapy (IT). Clin. Exp. Allergy 28, 943-949 (1998).
-
(1998)
Clin. Exp. Allergy
, vol.28
, pp. 943-949
-
-
Van Bever, H.P.1
Vereecke, I.F.2
Bridts, C.H.3
De Clerck, L.S.4
Stevens, W.J.5
-
126
-
-
0032873206
-
Short-term preseasonal birch pollen allergoid immunotherapy influences symptoms, specific nasal provocation and cytokine levels in nasal secretions, but not peripheral T-cell responses, in patients with allergic rhinitis
-
Klimek, L. et al. Short-term preseasonal birch pollen allergoid immunotherapy influences symptoms, specific nasal provocation and cytokine levels in nasal secretions, but not peripheral T-cell responses, in patients with allergic rhinitis. Clin. Exp. Allergy 29, 1326-1335 (1999).
-
(1999)
Clin. Exp. Allergy
, vol.29
, pp. 1326-1335
-
-
Klimek, L.1
-
127
-
-
5444254408
-
Toll-like receptors in the pathogenesis of human disease
-
Cook, D. N., Pisetsky, D. S. & Schwartz, D. A. Toll-like receptors in the pathogenesis of human disease. Nature Immunol. 5, 975-979 (2004).
-
(2004)
Nature Immunol.
, vol.5
, pp. 975-979
-
-
Cook, D.N.1
Pisetsky, D.S.2
Schwartz, D.A.3
-
128
-
-
0030956363
-
H1 shift, and changes surface marker expression in venom-allergic subjects
-
H1 shift, and changes surface marker expression in venom-allergic subjects. Eur. J. Immunol. 27, 1131-1139 (1997).
-
(1997)
Eur. J. Immunol.
, vol.27
, pp. 1131-1139
-
-
Bellinghausen, I.1
-
129
-
-
3042708626
-
Mechanisms of immunotherapy
-
Till, S. J., Francis, J. N., Nouri-Aria, K. & Durham, S. R. Mechanisms of immunotherapy. J. Allergy Clin. Immunol. 113, 1025-1034 (2004).
-
(2004)
J. Allergy Clin. Immunol.
, vol.113
, pp. 1025-1034
-
-
Till, S.J.1
Francis, J.N.2
Nouri-Aria, K.3
Durham, S.R.4
-
130
-
-
0038363534
-
IL-10 and TGP-β cooperate in the regulatory T cell response to mucosal allergens in normal immunity and specific immunotherapy
-
Jutel, M. et al. IL-10 and TGP-β cooperate in the regulatory T cell response to mucosal allergens in normal immunity and specific immunotherapy. Eur. J. Immunol. 33, 1205-1214 (2003).
-
(2003)
Eur. J. Immunol.
, vol.33
, pp. 1205-1214
-
-
Jutel, M.1
-
131
-
-
0042736703
-
Impaired secretion of interleukin-4 and interleukin-13 by allergen-specific T cells correlates with defective nuclear expression of NR-AT2 and jun B: Relevance to immunotherapy
-
Faith, A. et al. Impaired secretion of interleukin-4 and interleukin-13 by allergen-specific T cells correlates with defective nuclear expression of NR-AT2 and jun B: relevance to immunotherapy. Clin. Exp. Allergy 33, 1209-1215 (2003).
-
(2003)
Clin. Exp. Allergy
, vol.33
, pp. 1209-1215
-
-
Faith, A.1
-
132
-
-
0037031090
-
Effect of T-cell peptides derived from Fel d 1 on allergic reactions and cytokine production in patients sensitive to cats: A randomised controlled trial
-
Oldfield, W. L., Larche, M. & Kay, A. B. Effect of T-cell peptides derived from Fel d 1 on allergic reactions and cytokine production in patients sensitive to cats: a randomised controlled trial. Lancer 360, 47-53 (2002).
-
(2002)
Lancer
, vol.360
, pp. 47-53
-
-
Oldfield, W.L.1
Larche, M.2
Kay, A.B.3
-
133
-
-
85004905442
-
High IgG4 antibody level is associated with failure of immunotherapy with inhalant allergens
-
Djurup, R. & Malling, H. J. High IgG4 antibody level is associated with failure of immunotherapy with inhalant allergens. Clin. Allergy 17, 459-468 (1987).
-
(1987)
Clin. Allergy
, vol.17
, pp. 459-468
-
-
Djurup, R.1
Malling, H.J.2
-
134
-
-
0027337596
-
Venom-specific IgG antibodies in bee and wasp allergy: Lack of correlation with protection from stings
-
Ewan, P. W., Deighton, J., Wilson, A. B. & Lachmann, P. J. Venom-specific IgG antibodies in bee and wasp allergy: lack of correlation with protection from stings. Clin. Exp. Allergy 23, 647-660 (1993).
-
(1993)
Clin. Exp. Allergy
, vol.23
, pp. 647-660
-
-
Ewan, P.W.1
Deighton, J.2
Wilson, A.B.3
Lachmann, P.J.4
-
136
-
-
0030944340
-
2-specific human IgE and IgG4 antibodies in vitro requires allergen-specific and nonspecific activation of T and B cells
-
2-specific human IgE and IgG4 antibodies in vitro requires allergen-specific and nonspecific activation of T and B cells. J. Allergy Clin. Immunol. 99, 345-353 (1997). This is an early report of differential regulation of IgE and IgG4, which led to a series of publications (many of which are highlighted here) proposing that this is an important mechanism associated with successful allergen immunotherapy.
-
(1997)
J. Allergy Clin. Immunol.
, vol.99
, pp. 345-353
-
-
Akdis, C.A.1
-
137
-
-
0033197966
-
+ T cells by inhibiting serum-IgE-facilitated allergen presentation
-
+ T cells by inhibiting serum-IgE-facilitated allergen presentation. J. Immunol. 163, 2944-2952 (1999).
-
(1999)
J. Immunol.
, vol.163
, pp. 2944-2952
-
-
Van Neerven, R.J.1
-
138
-
-
0041735323
-
Induction of 'blocking' IgG antibodies during immunotherapy
-
Wachholz, P. A. & Durham, S. R. Induction of 'blocking' IgG antibodies during immunotherapy. Clin. Exp. Allergy 33, 1171-1174 (2003).
-
(2003)
Clin. Exp. Allergy
, vol.33
, pp. 1171-1174
-
-
Wachholz, P.A.1
Durham, S.R.2
-
139
-
-
0043258973
-
Inhibition of allergen-IgE binding to B cells by IgG antibodies after grass pollen immunotherapy
-
Wachholz, P. A., Soni, N. K., Till, S. J. & Durham, S. R. Inhibition of allergen-IgE binding to B cells by IgG antibodies after grass pollen immunotherapy. J. Allergy Clin. Immunol. 112, 915-922 (2003).
-
(2003)
J. Allergy Clin. Immunol.
, vol.112
, pp. 915-922
-
-
Wachholz, P.A.1
Soni, N.K.2
Till, S.J.3
Durham, S.R.4
-
140
-
-
0036888370
-
From allergen structure to new forms of allergen-specific immunotherapy
-
Valenta, R. & Kraft, D. From allergen structure to new forms of allergen-specific immunotherapy. Curr. Opin. Immunol. 14, 718-727 (2002).
-
(2002)
Curr. Opin. Immunol.
, vol.14
, pp. 718-727
-
-
Valenta, R.1
Kraft, D.2
-
141
-
-
0036174045
-
Efficacy of combination treatment with anti-IgE plus specific immunotherapy in polysensitized children and adolescents with seasonal allergic rhinitis
-
Kuehr, J. et al. Efficacy of combination treatment with anti-IgE plus specific immunotherapy in polysensitized children and adolescents with seasonal allergic rhinitis. J. Allergy Clin. Immunol. 109, 274-280 (2002).
-
(2002)
J. Allergy Clin. Immunol.
, vol.109
, pp. 274-280
-
-
Kuehr, J.1
-
142
-
-
20844433231
-
The co-seasonal application of anti-IgE after preseasonal specific immunotherapy decreases ocular and nasal symptom scores and rescue medication use in grass pollen allergic children
-
Rolinck-Weminghaus, C. et al. The co-seasonal application of anti-IgE after preseasonal specific immunotherapy decreases ocular and nasal symptom scores and rescue medication use in grass pollen allergic children. Allergy 59, 973-979 (2004).
-
(2004)
Allergy
, vol.59
, pp. 973-979
-
-
Rolinck-Weminghaus, C.1
-
143
-
-
0029066660
-
The high affinity IgE receptor (FcεRi) mediates IgE-dependent allergen presentation
-
Maurer, D. et al. The high affinity IgE receptor (FcεRi) mediates IgE-dependent allergen presentation. J. Immunol. 154, 6285-6290 (1995).
-
(1995)
J. Immunol.
, vol.154
, pp. 6285-6290
-
-
Maurer, D.1
-
144
-
-
0035878077
-
Engagement of FcεRI on human monocytes induces the production of IL-10 and prevents their differentiation in dendritic cells
-
Novak, N., Bieber, T. & Katoh, N. Engagement of FcεRI on human monocytes induces the production of IL-10 and prevents their differentiation in dendritic cells. J. Immunol. 167, 797-804 (2001). References 143 and 144 provide evidence that crosslinking of IgE regulates APC function.
-
(2001)
J. Immunol.
, vol.167
, pp. 797-804
-
-
Novak, N.1
Bieber, T.2
Katoh, N.3
-
146
-
-
8044227212
-
Treatment of cat allergy with T-cell reactive peptides
-
Norman, P. S. et al. Treatment of cat allergy with T-cell reactive peptides. Am. J. Respir. Crit. Care Med. 154, 1623-1628 (1996).
-
(1996)
Am. J. Respir. Crit. Care Med.
, vol.154
, pp. 1623-1628
-
-
Norman, P.S.1
-
147
-
-
0031866059
-
2 induces specific T-cell anergy in patients allergic to bee venom
-
2 induces specific T-cell anergy in patients allergic to bee venom. J. Allergy Clin. Immunol. 101, 747-754 (1998).
-
(1998)
J. Allergy Clin. Immunol.
, vol.101
, pp. 747-754
-
-
Muller, U.1
-
148
-
-
0033591638
-
Immunoglobulin E-independent major histocompatibility complex-restricted T cell peptide epitope-induced late asthmatic reactions
-
Haselden, B. M., Kay, A. B. & Larche, M. Immunoglobulin E-independent major histocompatibility complex-restricted T cell peptide epitope-induced late asthmatic reactions. J. Exp. Med. 189, 1885-1894 (1999). References 147 and 148 are independent studies that were the first to describe the successful use of peptides derived from allergen for use in allergen immunotherapy.
-
(1999)
J. Exp. Med.
, vol.189
, pp. 1885-1894
-
-
Haselden, B.M.1
Kay, A.B.2
Larche, M.3
-
149
-
-
0035423535
-
Allergen-derived T cell peptide-induced late asthmatic reactions precede the induction of antigen-specific hyporesponsiveness in atopic allergic asthmatic subjects
-
Oldfield, W. L., Kay, A. B. S. Larche, M. Allergen-derived T cell peptide-induced late asthmatic reactions precede the induction of antigen-specific hyporesponsiveness in atopic allergic asthmatic subjects. J. Immunol. 167, 1734-1739 (2001).
-
(2001)
J. Immunol.
, vol.167
, pp. 1734-1739
-
-
Oldfield, W.L.1
Kay, A.B.S.2
Larche, M.3
-
150
-
-
1242320985
-
Late asthmatic reactions induced by inhalation of allergen-derived T cell peptides
-
Ali, F. R., Oldfield, W. L., Higashi, N., Larche, M. & Kay A. B. Late asthmatic reactions induced by inhalation of allergen-derived T cell peptides. Am. J. Respir. Crit. Care Med. 169, 20-26 (2004).
-
(2004)
Am. J. Respir. Crit. Care Med.
, vol.169
, pp. 20-26
-
-
Ali, F.R.1
Oldfield, W.L.2
Higashi, N.3
Larche, M.4
Kay, A.B.5
-
151
-
-
0037395291
-
Allergen-specific T-cell tolerance induction with allergen-derived long synthetic peptides: Results of a Phase I trial
-
Fellrath, J. M. et al. Allergen-specific T-cell tolerance induction with allergen-derived long synthetic peptides: results of a Phase I trial. J. Allergy Clin. Immunol. 111, 854-861 (2003).
-
(2003)
J. Allergy Clin. Immunol.
, vol.111
, pp. 854-861
-
-
Fellrath, J.M.1
-
152
-
-
4644257344
-
Cat allergen peptide immunotherapy reduces CD4 T cell responses to cat allergen but does not alter suppression by CD4 CD25 T cells: A double-blind placebo-controlled study
-
Smith, T. R., Alexander, C., Kay, A. B., Larche, M. & Robinson, D. S. Cat allergen peptide immunotherapy reduces CD4 T cell responses to cat allergen but does not alter suppression by CD4 CD25 T cells: a double-blind placebo-controlled study. Allergy 59, 1097-1101 (2004).
-
(2004)
Allergy
, vol.59
, pp. 1097-1101
-
-
Smith, T.R.1
Alexander, C.2
Kay, A.B.3
Larche, M.4
Robinson, D.S.5
-
153
-
-
0027451437
-
Inhibition of T cell and antibody responses to house dust mite allergen by inhalation of the dominant T cell epitope in naive and sensitized mice
-
Hoyne, G. F., O'Hehir, R. E., Wraith, D. C., Thomas, W. R. & Lamb, J. R. Inhibition of T cell and antibody responses to house dust mite allergen by inhalation of the dominant T cell epitope in naive and sensitized mice. J. Exp. Med. 178, 1783-1788 (1993).
-
(1993)
J. Exp. Med.
, vol.178
, pp. 1783-1788
-
-
Hoyne, G.F.1
O'Hehir, R.E.2
Wraith, D.C.3
Thomas, W.R.4
Lamb, J.R.5
-
155
-
-
0036219195
-
CpG motifs in bacterial DNA and their immune effects
-
Krieg, A. M. CpG motifs in bacterial DNA and their immune effects. Annu. Rev. Immunol. 20, 709-760 (2002).
-
(2002)
Annu. Rev. Immunol.
, vol.20
, pp. 709-760
-
-
Krieg, A.M.1
-
156
-
-
3142724031
-
Toll-like receptor signalling
-
Akira, S. & Takeda, K. Toll-like receptor signalling. Nature Rev. Immunol. 4, 499-511 (2004).
-
(2004)
Nature Rev. Immunol.
, vol.4
, pp. 499-511
-
-
Akira, S.1
Takeda, K.2
-
157
-
-
0344737658
-
IL-10 regulates plasmacytoid dendritic cell response to CpG-containing immunostimulatory sequences
-
Duramad, O. et al. IL-10 regulates plasmacytoid dendritic cell response to CpG-containing immunostimulatory sequences. Blood 102, 4487-4492 (2003).
-
(2003)
Blood
, vol.102
, pp. 4487-4492
-
-
Duramad, O.1
-
158
-
-
11244280803
-
Combination immunotherapy with a CpG oligonucleotide (1018 ISS) and rituximab in patients with non-Hodgkin lymphoma: Increased interferon-α/ β-inducible gene expression, without significant toxicity
-
Friedberg, J. W. et al. Combination immunotherapy with a CpG oligonucleotide (1018 ISS) and rituximab in patients with non-Hodgkin lymphoma: increased interferon-α/β-induciblegene expression, without significant toxicity. Blood 105, 489-495 (2004).
-
(2004)
Blood
, vol.105
, pp. 489-495
-
-
Friedberg, J.W.1
-
159
-
-
0343953087
-
Conjugation of immunostimulatory DNA to the short ragweed allergen Amb a 1 enhances its immunogenidty and reduces its allergenicity
-
Tighe, H. et al. Conjugation of immunostimulatory DNA to the short ragweed allergen Amb a 1 enhances its immunogenidty and reduces its allergenicity. J. Allergy Clin. Immunol. 106, 124-134 (2000).
-
(2000)
J. Allergy Clin. Immunol.
, vol.106
, pp. 124-134
-
-
Tighe, H.1
-
160
-
-
17844371968
-
H2 cytokine expression in PBMCs from human patients with ragweed allergy
-
H2 cytokine expression in PBMCs from human patients with ragweed allergy. J. Allergy Clin. Immunol. 108, 191-197 (2001).
-
(2001)
J. Allergy Clin. Immunol.
, vol.108
, pp. 191-197
-
-
Marshal, J.D.1
-
161
-
-
1142273128
-
Amb a 1-immunostimulatoryoligodeoxynucleotide conjugate immunotherapy decreases the nasal inflammatory response
-
Tulic, M. K. et al. Amb a 1-immunostimulatoryoligodeoxynucleotide conjugate immunotherapy decreases the nasal inflammatory response. J. Allergy Clin. Immunol. 113, 235-241 (2004).
-
(2004)
J. Allergy Clin. Immunol.
, vol.113
, pp. 235-241
-
-
Tulic, M.K.1
-
162
-
-
3042718066
-
Selective immune redirection in humans with ragweed allergy by injecting Amb a 1 linked to immunostimulatory DNA
-
Simons, F. E., Shikishima, Y., Van Nest, G., Eiden, J. J. & HayGlass, K. T. Selective immune redirection in humans with ragweed allergy by injecting
-
(2004)
J. Allergy Clin. Immunol.
, vol.113
, pp. 1144-1151
-
-
Simons, F.E.1
Shikishima, Y.2
Van Nest, G.3
Eiden, J.J.4
HayGlass, K.T.5
-
163
-
-
0032838201
-
Antiinflammatory properties of mycophenolate mofetil in murine endotoxemia: Inhibition of TNF-α and upregulation of IL-10 release
-
Durez, P. et al. Antiinflammatory properties of mycophenolate mofetil in murine endotoxemia: inhibition of TNF-α and upregulation of IL-10 release. Int. J. Immunopharmacol. 21, 581-587 (1999).
-
(1999)
Int. J. Immunopharmacol.
, vol.21
, pp. 581-587
-
-
Durez, P.1
-
164
-
-
0027405362
-
In vivo induction of interteukin 10 by anti-CD3 monoclonal antibody or bacterial lipopolysaccharide: Differential modulation by cyclosporin A
-
Durez, P. et al. In vivo induction of interteukin 10 by anti-CD3 monoclonal antibody or bacterial lipopolysaccharide: differential modulation by cyclosporin A. J. Exp. Med. 177, 551-555 (1993).
-
(1993)
J. Exp. Med.
, vol.177
, pp. 551-555
-
-
Durez, P.1
-
165
-
-
0037201295
-
Immunomodulatory effects of vasoactive catecholamines
-
Bergmann, M. Sautner, T. Immunomodulatory effects of vasoactive catecholamines. Wien. Klin. Wochenschr. 114, 752-761 (2002).
-
(2002)
Wien. Klin. Wochenschr.
, vol.114
, pp. 752-761
-
-
Bergmann, M.1
Sautner, T.2
-
166
-
-
0036667395
-
Adenosine: A potential mediator of immunosuppression in multiple organ failure
-
Hasko, G., Deitch, E. A., Szabo, C., Nemeth, Z. H. & Vizi, E. S. Adenosine: a potential mediator of immunosuppression in multiple organ failure. Curr. Opin. Pharmacol. 2, 440-444 (2002).
-
(2002)
Curr. Opin. Pharmacol.
, vol.2
, pp. 440-444
-
-
Hasko, G.1
Deitch, E.A.2
Szabo, C.3
Nemeth, Z.H.4
Vizi, E.S.5
-
167
-
-
0033168605
-
Differential cytokine modulation and T cell activation by two distinct classes of thalidomide analogues that are potent inhibitors of TNF-α
-
Corral, L. G. et al. Differential cytokine modulation and T cell activation by two distinct classes of thalidomide analogues that are potent inhibitors of TNF-α. J. Immunol. 163, 380-386 (1999).
-
(1999)
J. Immunol.
, vol.163
, pp. 380-386
-
-
Corral, L.G.1
-
168
-
-
0344585385
-
H2-mediated airway inflammation by the sphingosine 1-phosphate receptor agonist FTY720
-
H2-mediated airway inflammation by the sphingosine 1-phosphate receptor agonist FTY720. J. Immunol. 171, 6206-6214 (2003).
-
(2003)
J. Immunol.
, vol.171
, pp. 6206-6214
-
-
Sawicka, E.1
-
169
-
-
0038476461
-
Enhancement of cytokine production and AP-1 transcriptional activity in T cells by thalidomide-relatedimmunomodulatory drugs
-
Schafer, P. H. et al. Enhancement of cytokine production and AP-1 transcriptional activity in T cells by thalidomide-relatedimmunomodulatory drugs. J. Phamacol. Exp. Ther. 305, 1222-1232 (2003).
-
(2003)
J. Phamacol. Exp. Ther.
, vol.305
, pp. 1222-1232
-
-
Schafer, P.H.1
-
170
-
-
1542605351
-
Regulation of human peripheral blood lymphocytes IL-10 by SMS 201-995
-
Casnici, C., Lattuada, D., Franco, P., Cattaneo, L. & Marelli, O. Regulation of human peripheral blood lymphocytes IL-10 by SMS 201-995. J. Neuroimmunol. 149, 210-216 (2004).
-
(2004)
J. Neuroimmunol.
, vol.149
, pp. 210-216
-
-
Casnici, C.1
Lattuada, D.2
Franco, P.3
Cattaneo, L.4
Marelli, O.5
-
171
-
-
0031028218
-
Cytokineresponses to cardiopulmonary bypass: Lessons learned from cardiac transplantation
-
Wan, S., LeClerc, J. L. & Vincent, J. L. Cytokineresponses to cardiopulmonary bypass: lessons learned from cardiac transplantation. Ann. Thorac. Surg. 63, 269-276 (1997).
-
(1997)
Ann. Thorac. Surg.
, vol.63
, pp. 269-276
-
-
Wan, S.1
LeClerc, J.L.2
Vincent, J.L.3
-
172
-
-
0031943945
-
Inhaled corticosteroids increase interteukin-10 but reduce macrophage inflammatory protein-1α, granulocyte-macrophage colony-stimulating factor and interferon-γ release from alveolar macrophages in asthma
-
John, M. et al. Inhaled corticosteroids increase interteukin-10 but reduce macrophage inflammatory protein-1α, granulocyte-macrophage colony-stimulating factor and interferon-γ release from alveolar macrophages in asthma. Am. J. Respir. Crit. Care Med. 157, 256-262 (1998).
-
(1998)
Am. J. Respir. Crit. Care Med.
, vol.157
, pp. 256-262
-
-
John, M.1
-
173
-
-
0036173939
-
A defect in corticosteroid-induced IL-10 production in T lymphocytes from corticosteroid-resistant asthmatic patients
-
Hawrylowicz, C., Richards, D., Loke, T. K., Corrigan, C. & Lee, T. A defect in corticosteroid-induced IL-10 production in T lymphocytes from corticosteroid-resistant asthmatic patients. J. Allergy Clin. Immunol. 109, 369-370 (2002). This paper provides evidence that correlates failure to respond clinically to glucocorticoid treatment with a defect in T-cell responsiveness to glucocorticoids that results in reduced IL-10 expression in vitro.
-
(2002)
J. Allergy Clin. Immunol.
, vol.109
, pp. 369-370
-
-
Hawrylowicz, C.1
Richards, D.2
Loke, T.K.3
Corrigan, C.4
Lee, T.5
-
174
-
-
17144375158
-
H2 cytokine responses and enhances IL-10 responses
-
H2 cytokine responses and enhances IL-10 responses. J. Allergy Clin. Immunol. 113 (Suppl.), A753 (2004).
-
(2004)
J. Allergy Clin. Immunol.
, vol.113
, Issue.SUPPL.
-
-
Peek, E.1
-
175
-
-
0033663565
-
Opposing effects of dehydroepandrosterone and dexamethasone on the generation of monocyte-derived dendritic cells
-
Canning, M. O., Grotenhue, K., de Wit, H. J. &Drexhage, H. A. Opposing effects of dehydroepandrosterone and dexamethasone on the generation of monocyte-derived dendritic cells. Eur. J. Endocrinol. 143, 687-695 (2000).
-
(2000)
Eur. J. Endocrinol.
, vol.143
, pp. 687-695
-
-
Canning, M.O.1
Grotenhue, K.2
De Wit, H.J.3
Drexhage, H.A.4
-
176
-
-
0141853304
-
Generation of antigen-specific, interleukin-10-producing T-cells using dendritic ceil stimulation and steroid hormone conditioning
-
Dong, X., Bachman, L. A., Kumar, R. & Griffin, M. D. Generation of antigen-specific, interleukin-10-producing T-cells using dendritic ceil stimulation and steroid hormone conditioning. Transpl. Immunol. 11, 323-333 (2003).
-
(2003)
Transpl. Immunol.
, vol.11
, pp. 323-333
-
-
Dong, X.1
Bachman, L.A.2
Kumar, R.3
Griffin, M.D.4
-
177
-
-
0036717722
-
H2 paradigm in immunity to infectious diseases
-
H2 paradigm in immunity to infectious diseases. Trends Immunol. 23, 450-455 (2002).
-
(2002)
Trends Immunol.
, vol.23
, pp. 450-455
-
-
McGuirk, P.1
Mills, K.H.2
-
178
-
-
0036278230
-
Suppression of airway eosinophilia by killed Mycobacterium vaccae-induced allergen-specific regulatory T-cells
-
Zuany-Amorim, C. et al. Suppression of airway eosinophilia by killed Mycobacterium vaccae-induced allergen-specific regulatory T-cells. Nature Med. 8, 625-629 (2002).
-
(2002)
Nature Med.
, vol.8
, pp. 625-629
-
-
Zuany-Amorim, C.1
-
179
-
-
0034828502
-
Expression of cytokines, inducible nitric oxide synthase, and matrix metalloproteinases in pouchrtis: Effects of probiotic treatment
-
Ulisse, S. et al. Expression of cytokines, inducible nitric oxide synthase, and matrix metalloproteinases in pouchrtis: effects of probiotic treatment. Am. J. Gastroenterol. 96, 2691-2699 (2001).
-
(2001)
Am. J. Gastroenterol.
, vol.96
, pp. 2691-2699
-
-
Ulisse, S.1
-
180
-
-
0038730917
-
Probiotics and prevention of atopic disease: 4-Year follow-up of a randomised placebo-controlled trial
-
Kalliomaki, M., Salminen, S., Poussa, T., Arvilommi, H. & Isolauri, E. Probiotics and prevention of atopic disease: 4-year follow-up of a randomised placebo-controlled trial. Lance 361, 1869-1871 (2003).
-
(2003)
Lance
, vol.361
, pp. 1869-1871
-
-
Kalliomaki, M.1
Salminen, S.2
Poussa, T.3
Arvilommi, H.4
Isolauri, E.5
-
183
-
-
0033987397
-
+ T helper cells engineered to produce latent TGF-β1 reverse allergen-induced airway hyperreactivity and inflammation
-
+ T helper cells engineered to produce latent TGF-β1 reverse allergen-induced airway hyperreactivity and inflammation. J. Clin. Invest. 105, 61-70 (2000).
-
(2000)
J. Clin. Invest.
, vol.105
, pp. 61-70
-
-
Hansen, G.1
-
184
-
-
0346751969
-
Effect of Mycobacterium vaccae on atopic dermatitis in children of different ages
-
Arkwright, P. D. & David, T. J. Effect of Mycobacterium vaccae on atopic dermatitis in children of different ages. Br. J. Dermatol. 149, 1029-1034 (2003).
-
(2003)
Br. J. Dermatol.
, vol.149
, pp. 1029-1034
-
-
Arkwright, P.D.1
David, T.J.2
-
185
-
-
0036372440
-
Transforming growth factor-β in T-cell biology
-
Gorelik, L. & Flavell, R. A. Transforming growth factor-β in T-cell biology. Nature Rev. Immunol. 2, 46-53 (2002).
-
(2002)
Nature Rev. Immunol.
, vol.2
, pp. 46-53
-
-
Gorelik, L.1
Flavell, R.A.2
-
186
-
-
0036907478
-
CD4 CD25 regulatory T cells are not functionally impaired in adult patients with IgE-mediated cow's milk allergy
-
Tiemessen, M. M. et al. CD4 CD25 regulatory T cells are not functionally impaired in adult patients with IgE-mediated cow's milk allergy. J. Allergy Clin. Immunol. 110, 934-936 (2002).
-
(2002)
J. Allergy Clin. Immunol.
, vol.110
, pp. 934-936
-
-
Tiemessen, M.M.1
-
187
-
-
0036257312
-
Expression and function of histamine receptors in human monocyte-derived dendritic cells
-
Idzko, M. et al. Expression and function of histamine receptors in human monocyte-derived dendritic cells. J. Allergy Clin. Immunol. 109, 839-846 (2002).
-
(2002)
J. Allergy Clin. Immunol.
, vol.109
, pp. 839-846
-
-
Idzko, M.1
-
188
-
-
0037709966
-
H2 responses
-
H2 responses. FASEB J. 17, 1089-1095 (2003).
-
(2003)
FASEB J.
, vol.17
, pp. 1089-1095
-
-
Kunzmann, S.1
|