메뉴 건너뛰기




Volumn 2, Issue 1, 2002, Pages 46-53

Transforming growth factor-β in T-cell biology

Author keywords

[No Author keywords available]

Indexed keywords

ANTIGEN; CLASS II TRANSACTIVATOR PROTEIN; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; T LYMPHOCYTE RECEPTOR; TRANSACTIVATOR PROTEIN; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR GATA; TRANSFORMING GROWTH FACTOR BETA; UNCLASSIFIED DRUG; AUTOANTIGEN;

EID: 0036372440     PISSN: 14741733     EISSN: None     Source Type: Journal    
DOI: 10.1038/nri704     Document Type: Review
Times cited : (737)

References (75)
  • 1
    • 0026799402 scopus 로고
    • Targeted disruption of the mouse transforming growth factor-β1 gene results in multifocal inflammatory disease
    • Shull, M. M. et al. Targeted disruption of the mouse transforming growth factor-β1 gene results in multifocal inflammatory disease. Nature 359, 693-699 (1992).
    • (1992) Nature , vol.359 , pp. 693-699
    • Shull, M.M.1
  • 2
    • 0027531528 scopus 로고
    • Transforming growth factor β1 null mutation in mice causes excessive inflammatory response and early death
    • Kulkarni, A. B. et al. Transforming growth factor β1 null mutation in mice causes excessive inflammatory response and early death Proc. Natl Acad. Sci USA 90, 770-774 (1993).
    • (1993) Proc. Natl. Acad. Sci USA , vol.90 , pp. 770-774
    • Kulkarni, A.B.1
  • 3
    • 0028806184 scopus 로고
    • Abnormal lung development and cleft palate in mice lacking TGF-β3 indicates defects of epithelial-mesenchymal interaction
    • Kaartinen, V. et al. Abnormal lung development and cleft palate in mice lacking TGF-β3 indicates defects of epithelial-mesenchymal interaction. Nature Genet. 11, 415-421 (1995).
    • (1995) Nature Genet. , vol.11 , pp. 415-421
    • Kaartinen, V.1
  • 4
    • 0028972869 scopus 로고
    • Transforming growth factor-β3 is required for secondary palate fusion
    • Proetzel, G. et al. Transforming growth factor-β3 is required for secondary palate fusion. Nature Genet. 11, 409-414 (1995).
    • (1995) Nature Genet. , vol.11 , pp. 409-414
    • Proetzel, G.1
  • 5
    • 0030609894 scopus 로고    scopus 로고
    • TGFβ2 knockout mice have multiple developmental defects that are non-overlapping with other TGFβ knockout phenotypes
    • Sanford, L. P. et al. TGFβ2 knockout mice have multiple developmental defects that are non-overlapping with other TGFβ knockout phenotypes. Development 124, 2659-2670 (1997).
    • (1997) Development , vol.124 , pp. 2659-2670
    • Sanford, L.P.1
  • 6
    • 0025358706 scopus 로고
    • Susceptibility and resistance of human autoimmune T cell activation to the immunoregulatory effects of transforming growth factor (TGF)β1, β2, and β1.2
    • Schluesener, H., Jung, S. & Salvetti, M. Susceptibility and resistance of human autoimmune T cell activation to the immunoregulatory effects of transforming growth factor (TGF)β1, β2, and β1.2. J. Neuroimmunol. 28, 271-276 (1990).
    • (1990) J. Neuroimmunol. , vol.28 , pp. 271-276
    • Schluesener, H.1    Jung, S.2    Salvetti, M.3
  • 7
    • 0024398741 scopus 로고
    • Comparison of the immunosuppressive properties of milk growth factor and transforming growth factors β1 and β2
    • Stoeck, M. et al. Comparison of the immunosuppressive properties of milk growth factor and transforming growth factors β1 and β2. J. Immunol. 143, 3258-3265 (1989).
    • (1989) J. Immunol. , vol.143 , pp. 3258-3265
    • Stoeck, M.1
  • 8
    • 0022465625 scopus 로고
    • Production of transforming growth factor β by human T lymphocytes and its potential role in the regulation of T cell growth
    • Kehrl, J. H. et al. Production of transforming growth factor β by human T lymphocytes and its potential role in the regulation of T cell growth. J. Exp. Med. 163, 1037-1050 (1986). First demonstration of the important role of TGF-β in T-cell regulation.
    • (1986) J. Exp. Med. , vol.163 , pp. 1037-1050
    • Kehrl, J.H.1
  • 9
    • 0027392761 scopus 로고
    • Transforming growth factor β and cyclosporin A inhibit the inducible activity of the interleukin-2 gene in T cells through a noncanonical octamer-binding site
    • Brabletz, T. et al. Transforming growth factor β and cyclosporin A inhibit the inducible activity of the interleukin-2 gene in T cells through a noncanonical octamer-binding site. Mol. Cell. Biol. 13, 1155-1162 (1993).
    • (1993) Mol. Cell. Biol. , vol.13 , pp. 1155-1162
    • Brabletz, T.1
  • 10
    • 0028168242 scopus 로고
    • p151NK4B is a potential effector of TGF-β-induced cell cycle arrest
    • Hannon, G. J. & Beach, D. p151NK4B is a potential effector of TGF-β-induced cell cycle arrest. Nature 371, 257-261 (1994).
    • (1994) Nature , vol.371 , pp. 257-261
    • Hannon, G.J.1    Beach, D.2
  • 11
    • 0029073142 scopus 로고
    • Transforming growth factor β induces the cyclin-dependent kinase inhibitor p21 through a p53-independent mechanism
    • Datto, M. B. et al. Transforming growth factor β induces the cyclin-dependent kinase inhibitor p21 through a p53-independent mechanism. Proc. Natl Acad. Sci. USA 92, 5545-5549 (1995).
    • (1995) Proc. Natl. Acad. Sci. USA , vol.92 , pp. 5545-5549
    • Datto, M.B.1
  • 12
    • 0028179669 scopus 로고
    • p27Kip1, a cyclin-Cdk inhibitor, links transforming growth factor-β and contact inhibition to cell cycle arrest
    • Polyak, K. et al. p27Kip1, a cyclin-Cdk inhibitor, links transforming growth factor-β and contact inhibition to cell cycle arrest. Genes Dev. 8, 9-22 (1994).
    • (1994) Genes Dev. , vol.8 , pp. 9-22
    • Polyak, K.1
  • 13
    • 0023691647 scopus 로고
    • Selective inhibition of growth-related gene expression in murine keratinocytes by transforming growth factor β
    • Coffey, R. J. Jr. et al. Selective inhibition of growth-related gene expression in murine keratinocytes by transforming growth factor β. Mol. Cell. Biol. 8, 3088-3093 (1988).
    • (1988) Mol. Cell. Biol. , vol.8 , pp. 3088-3093
    • Coffey R.J., Jr.1
  • 14
    • 0027959893 scopus 로고
    • H2 cytokine secretion phenotype
    • H2 cytokine secretion phenotype. J. Immunol. 153, 3514-3522 (1994).
    • (1994) J. Immunol. , vol.153 , pp. 3514-3522
    • Sad, S.1    Mosmann, T.R.2
  • 15
    • 0025951644 scopus 로고
    • Transforming growth factor-β and IL-4 cause helper T cell precursors to develop into distinct effector helper cells that differ in lymphokine secretion pattern and cell surface phenotype
    • Swain, S. L., Huston, G., Tonkonogy, S. & Weinberg, A. Transforming growth factor-β and IL-4 cause helper T cell precursors to develop into distinct effector helper cells that differ in lymphokine secretion pattern and cell surface phenotype. J. Immunol. 147, 2991-3000 (1991).
    • (1991) J. Immunol. , vol.147 , pp. 2991-3000
    • Swain, S.L.1    Huston, G.2    Tonkonogy, S.3    Weinberg, A.4
  • 16
    • 0023583780 scopus 로고
    • Inhibition of cytotoxic T cell development by transforming growth factor β and reversal by recombinant tumor necrosis factor α
    • Ranges, G. E., Figari, I. S. Espevik, T. & Palladino, M. A. Jr. Inhibition of cytotoxic T cell development by transforming growth factor β and reversal by recombinant tumor necrosis factor α. J. Exp. Med. 166, 991-998 (1987).
    • (1987) J. Exp. Med. , vol.166 , pp. 991-998
    • Ranges, G.E.1    Figari, I.S.2    Espevik, T.3    Palladino M.A., Jr.4
  • 17
    • 0028984172 scopus 로고
    • + T cells isolated from different mouse strains
    • + T cells isolated from different mouse strains. J. Immunol. 155, 3788-3793 (1995).
    • (1995) J. Immunol. , vol.155 , pp. 3788-3793
    • Hoehn, P.1
  • 18
    • 0032212187 scopus 로고    scopus 로고
    • IL-4 in combination with TGF-β favors an alternative pathway of T.1 development independent of IL-12
    • Lingnau, K. et al. IL-4 in combination with TGF-β favors an alternative pathway of T.1 development independent of IL-12. J. Immunol. 161, 4709-4718 (1998).
    • (1998) J. Immunol. , vol.161 , pp. 4709-4718
    • Lingnau, K.1
  • 19
    • 0031587828 scopus 로고    scopus 로고
    • The MAD-related protein Smad7 associates with the TGFβ receptor and functions as an antagonist of TGFβ signaling
    • Hayashi, H. et al. The MAD-related protein Smad7 associates with the TGFβ receptor and functions as an antagonist of TGFβ signaling. Cell 89, 1165-1173 (1997).
    • (1997) Cell , vol.89 , pp. 1165-1173
    • Hayashi, H.1
  • 20
    • 0030611757 scopus 로고    scopus 로고
    • Identification of Smad7, a TGFβ-inducible antagonist of TGF-β signalling
    • Nakao, A. et al. Identification of Smad7, a TGFβ-inducible antagonist of TGF-β signalling. Nature 389, 631-635 (1997).
    • (1997) Nature , vol.389 , pp. 631-635
    • Nakao, A.1
  • 21
    • 0033602101 scopus 로고    scopus 로고
    • Inhibition of transforming growth factor-β/SMAD signalling by the interferon-γ/STAT pathway
    • Ulloa, L., Doody, J. & Massague, J. Inhibition of transforming growth factor-β/SMAD signalling by the interferon-γ/STAT pathway. Nature 397, 710-713 (1999).
    • (1999) Nature , vol.397 , pp. 710-713
    • Ulloa, L.1    Doody, J.2    Massague, J.3
  • 22
    • 0034596817 scopus 로고    scopus 로고
    • Interferon-γ signaling alters the function of T helper type 1 cells
    • Tau, G. Z. et al. Interferon-γ signaling alters the function of T helper type 1 cells. J. Exp. Med. 192, 977-986 (2000).
    • (2000) J. Exp. Med. , vol.192 , pp. 977-986
    • Tau, G.Z.1
  • 23
    • 0034600789 scopus 로고    scopus 로고
    • Treatment of experimental (trinitrobenzene sulfonic acid) colitis by intranasal administration of transforming growth factor (TGF)-β1 plasmid: TGF-β1-mediated suppression of T helper cell type 1 response occurs by interleukin (IL)-10 induction and IL-12 receptor β2 chain downregulation
    • Kitani, A. et al. Treatment of experimental (trinitrobenzene sulfonic acid) colitis by intranasal administration of transforming growth factor (TGF)-β1 plasmid: TGF-β1-mediated suppression of T helper cell type 1 response occurs by interleukin (IL)-10 induction and IL-12 receptor β2 chain downregulation. J. Exp. Med. 192, 41-52 (2000).
    • (2000) J. Exp. Med. , vol.192 , pp. 41-52
    • Kitani, A.1
  • 25
    • 0034327176 scopus 로고    scopus 로고
    • H type 2 development through inhibition of GATA-3 expression
    • H type 2 development through inhibition of GATA-3 expression. J. Immunol. 166, 4773-4777 (2000).
    • (2000) J. Immunol. , vol.166 , pp. 4773-4777
    • Gorelik, L.1    Fields, P.E.2    Flavell, R.A.3
  • 27
  • 29
    • 0034677646 scopus 로고    scopus 로고
    • H1 lineage commitment
    • H1 lineage commitment. Cell 100, 655-669 (2000). Cloning of a new T-box protein, T-bet, and demonstration of the important role it has in IFN-γ production.
    • (2000) Cell , vol.100 , pp. 655-669
    • Szabo, S.J.1
  • 30
    • 0035827347 scopus 로고    scopus 로고
    • H1 cells before IL-12-dependent selection
    • H1 development.
    • (2001) Science , vol.292 , pp. 1907-1910
    • Mullen, A.C.1
  • 31
    • 0035144325 scopus 로고    scopus 로고
    • Maternal VegT is the initiator of a molecular network specifying endoderm in Xenopus laevis
    • Xanthos, J. B., Kofron, M., Wylie, C. & Heaeman, J. Maternal VegT is the initiator of a molecular network specifying endoderm in Xenopus laevis. Development 128, 167-180 (2001).
    • (2001) Development , vol.128 , pp. 167-180
    • Xanthos, J.B.1    Kofron, M.2    Wylie, C.3    Heaeman, J.4
  • 33
    • 0032933798 scopus 로고    scopus 로고
    • In vivo analysis using variants of zebrafish BMPR-IA: Range of action and involvement of BMP in ectoderm patterning
    • Nikaido, M., Tada, M., Takeda, H., Kuroiwa, A. & Ueno, N. In vivo analysis using variants of zebrafish BMPR-IA: range of action and involvement of BMP in ectoderm patterning. Development 126, 181-190 (1999).
    • (1999) Development , vol.126 , pp. 181-190
    • Nikaido, M.1    Tada, M.2    Takeda, H.3    Kuroiwa, A.4    Ueno, N.5
  • 34
    • 0033923749 scopus 로고    scopus 로고
    • Vertebrate mesendoderm induction and patterning
    • Kimelman, D. & Griffin, K. J. Vertebrate mesendoderm induction and patterning. Curr. Opin. Genet. Dev. 10, 350-356 (2000).
    • (2000) Curr. Opin. Genet. Dev. , vol.10 , pp. 350-356
    • Kimelman, D.1    Griffin, K.J.2
  • 35
    • 0033554726 scopus 로고    scopus 로고
    • Two subsets of memory T lymphocytes with distinct homing potentials and effector functions
    • Sallusto, F., Lenig, D., Forster, R., Lipp, M. & Lanzavecchia, A. Two subsets of memory T lymphocytes with distinct homing potentials and effector functions. Nature 401, 708-712 (1999).
    • (1999) Nature , vol.401 , pp. 708-712
    • Sallusto, F.1    Lenig, D.2    Forster, R.3    Lipp, M.4    Lanzavecchia, A.5
  • 36
    • 0029149596 scopus 로고
    • Control of CD4 effector fate: Transforming growth factor β1 and interleukin 2 synergize to prevent apoptosis and promote effector expansion
    • Zhang, X., Giangreco, L., Broome, H. E., Dargan, C. M. & Swain, S. L. Control of CD4 effector fate: transforming growth factor β1 and interleukin 2 synergize to prevent apoptosis and promote effector expansion. J. Exp. Med. 182, 699-709 (1995).
    • (1995) J. Exp. Med. , vol.182 , pp. 699-709
    • Zhang, X.1    Giangreco, L.2    Broome, H.E.3    Dargan, C.M.4    Swain, S.L.5
  • 37
    • 0033579820 scopus 로고    scopus 로고
    • Transforming growth factor β1 inhibits Fas ligand expression and subsequent activation-induced cell death in T cells via downregulation of c-Myc
    • Genestier, L., Kasibhatla, S., Brunner, T. & Green, D. R. Transforming growth factor β1 inhibits Fas ligand expression and subsequent activation-induced cell death in T cells via downregulation of c-Myc. J. Exp. Med. 189, 231-239 (1999).
    • (1999) J. Exp. Med. , vol.189 , pp. 231-239
    • Genestier, L.1    Kasibhatla, S.2    Brunner, T.3    Green, D.R.4
  • 38
    • 0034131557 scopus 로고    scopus 로고
    • Abrogation of TGFβ signaling in T cells leads to spontaneous T cell differentiation and autoimmune disease
    • Gorelik, L. & Flavell, R. A. Abrogation of TGFβ signaling in T cells leads to spontaneous T cell differentiation and autoimmune disease. Immunity 12, 171-181 (2000).
    • (2000) Immunity , vol.12 , pp. 171-181
    • Gorelik, L.1    Flavell, R.A.2
  • 39
    • 0027500836 scopus 로고
    • Transforming growth factor β1 (TGF-β1) controls expression of major histocompatibility genes in the postnatal mouse: Aberrant histocompatibility antigen expression in the pathogenesis of the TGF-β1 null mouse phenotype
    • Geiser, A. G. et al. Transforming growth factor β1 (TGF-β1) controls expression of major histocompatibility genes in the postnatal mouse: aberrant histocompatibility antigen expression in the pathogenesis of the TGF-β1 null mouse phenotype. Proc. Natl Acad. Sci. USA 90, 9944-9948 (1993).
    • (1993) Proc. Natl. Acad. Sci. USA , vol.90 , pp. 9944-9948
    • Geiser, A.G.1
  • 40
    • 0034600070 scopus 로고    scopus 로고
    • Disruption of T cell homeostasis in mice expressing a T cell-specific dominant negative transforming growth factor βII receptor
    • Lucas, P. J., Kim, S. J., Melby, S. J. & Gress, R. E. Disruption of T cell homeostasis in mice expressing a T cell-specific dominant negative transforming growth factor βII receptor. J. Exp. Med. 191, 1187-1196 (2000).
    • (2000) J. Exp. Med. , vol.191 , pp. 1187-1196
    • Lucas, P.J.1    Kim, S.J.2    Melby, S.J.3    Gress, R.E.4
  • 41
    • 0034679703 scopus 로고    scopus 로고
    • Blockade of transforming growth factor beta/Smad signaling in T cells by overexpression of Smad7 enhances antigen-induced airway inflammation and airway reactivity
    • Nakao, A. et al. Blockade of transforming growth factor beta/Smad signaling in T cells by overexpression of Smad7 enhances antigen-induced airway inflammation and airway reactivity. J. Exp. Med. 192, 151-158 (2000).
    • (2000) J. Exp. Med. , vol.192 , pp. 151-158
    • Nakao, A.1
  • 42
    • 0026551703 scopus 로고
    • In vivo and in vitro clonal deletion of double-positive thymocytes
    • Vasquez, N. J., Kaye, J. & Hedrick, S. M. In vivo and in vitro clonal deletion of double-positive thymocytes. J. Exp. Med. 175, 1307-1316 (1992).
    • (1992) J. Exp. Med. , vol.175 , pp. 1307-1316
    • Vasquez, N.J.1    Kaye, J.2    Hedrick, S.M.3
  • 43
    • 0026585781 scopus 로고
    • RAG-1-deficient mice have no mature B and T lymphocytes
    • Mombaerts, P. et al. RAG-1-deficient mice have no mature B and T lymphocytes. Cell 68, 869-877 (1992).
    • (1992) Cell , vol.68 , pp. 869-877
    • Mombaerts, P.1
  • 44
    • 0032425062 scopus 로고    scopus 로고
    • Helicobacter hepaticus triggers colitis in specific-pathogen-free interleukin-10 (IL-10)-deficient mice through an IL-12-and γ -interferon-dependent mechanism
    • Kullberg, M. C. et al. Helicobacter hepaticus triggers colitis in specific-pathogen-free interleukin-10 (IL-10)-deficient mice through an IL-12-and γ-interferon-dependent mechanism. Infect. Immun. 66, 5157-5166 (1998).
    • (1998) Infect. Immun. , vol.66 , pp. 5157-5166
    • Kullberg, M.C.1
  • 45
    • 0034894059 scopus 로고    scopus 로고
    • Blocking Smad7 restores TGF-β1 signaling in chronic inflammatory bowel disease
    • Monteleone, G. et al. Blocking Smad7 restores TGF-β1 signaling in chronic inflammatory bowel disease. J. Clin. Invest. 108, 601-609 (2001).
    • (2001) J. Clin. Invest. , vol.108 , pp. 601-609
    • Monteleone, G.1
  • 46
    • 0035978651 scopus 로고    scopus 로고
    • Association of NOD2 leucine-rich repeat vadants with susceptibility to Crohn's disease
    • Hugot, J. P. et al. Association of NOD2 leucine-rich repeat vadants with susceptibility to Crohn's disease. Nature 411, 599-603 (2001).
    • (2001) Nature , vol.411 , pp. 599-603
    • Hugot, J.P.1
  • 47
    • 0035978533 scopus 로고    scopus 로고
    • A frameshift mutation in NOD2 associated with susceptibility to Crohn's disease
    • Ogura, Y. et al. A frameshift mutation in NOD2 associated with susceptibility to Crohn's disease. Nature 411, 603-606 (2001).
    • (2001) Nature , vol.411 , pp. 603-606
    • Ogura, Y.1
  • 48
    • 0035801335 scopus 로고    scopus 로고
    • + regulatory T cells is mediated by cell surface-bound transforming growth factor β
    • + regulatory T cells is mediated by cell surface-bound transforming growth factor β. J. Exp. Med. 194, 629-644 (2001).
    • (2001) J. Exp. Med. , vol.194 , pp. 629-644
    • Nakamura, K.1    Kitani, A.2    Strober, W.3
  • 49
    • 0029150110 scopus 로고
    • Immunologic self-tolerance maintained by activated T cells expressing IL-2 receptor α-chains (CD25). Breakdown of a single mechanism of self-tolerance causes various autoimmune diseases
    • + T cells in the regulation of autoimmunity.
    • (1995) J. Immunol. , vol.155 , pp. 1151-1164
    • Sakaguchi, S.1    Sakaguchi, N.2    Asano, M.3    Itoh, M.4    Toda, M.5
  • 50
    • 0031647622 scopus 로고    scopus 로고
    • +, naturally anergic and suppressive T cells: Induction of autoimmune disease by breaking their anergic/suppressive state
    • +, naturally anergic and suppressive T cells: induction of autoimmune disease by breaking their anergic/suppressive state. Int. Immunol. 10, 1969-1980 (1998).
    • (1998) Int. Immunol. , vol.10 , pp. 1969-1980
    • Takahashi, T.1
  • 51
    • 0034084162 scopus 로고    scopus 로고
    • Regulatory T cells in autoimmmunity
    • Shevach, E. M. Regulatory T cells in autoimmmunity. Annu. Rev. Immunol. 18, 423-449 (2000).
    • (2000) Annu. Rev. Immunol. , vol.18 , pp. 423-449
    • Shevach, E.M.1
  • 52
    • 0034716925 scopus 로고    scopus 로고
    • Regulatory T cells: Key controllers of immunologic self-tolerance
    • Sakaguchi, S. Regulatory T cells: key controllers of immunologic self-tolerance. Cell 101, 455-458 (2000).
    • (2000) Cell , vol.101 , pp. 455-458
    • Sakaguchi, S.1
  • 54
    • 0031821875 scopus 로고    scopus 로고
    • + immunoregulatory T cells suppress polyclonal T cell activation in vitro by inhibiting interleukin 2 production
    • + immunoregulatory T cells suppress polyclonal T cell activation in vitro by inhibiting interleukin 2 production. J. Exp. Med. 168, 287-296 (1998).
    • (1998) J. Exp. Med. , vol.168 , pp. 287-296
    • Thornton, A.M.1    Shevach, E.M.2
  • 55
    • 0034604029 scopus 로고    scopus 로고
    • A receptor for phosphatidylserine-specific clearance of apoptotic cells
    • Fadok, V. A. et al. A receptor for phosphatidylserine-specific clearance of apoptotic cells. Nature 405, 85-90 (2000). Cloning of the phosphatidylserine specific receptor and demonstration of its role in the TGF-β production by macrophages in response to apoptotic cells.
    • (2000) Nature , vol.405 , pp. 85-90
    • Fadok, V.A.1
  • 56
    • 0032695108 scopus 로고    scopus 로고
    • Natural adjuvants: Endogenous activators of dendritic cells
    • Gallucci, S., Lolkema, M. & Matzinger, P. Natural adjuvants: endogenous activators of dendritic cells. Nature Med. 5, 1249-1255 (1999).
    • (1999) Nature Med. , vol.5 , pp. 1249-1255
    • Gallucci, S.1    Lolkema, M.2    Matzinger, P.3
  • 57
    • 0034960320 scopus 로고    scopus 로고
    • TGF-β released by apoptotic T cells contributes to an immunosuppressive milieu
    • Chen, W., Frank, M. E., Jin, W. & Wahl, S. M. TGF-β released by apoptotic T cells contributes to an immunosuppressive milieu. Immunity 14, 715-725 (2001).
    • (2001) Immunity , vol.14 , pp. 715-725
    • Chen, W.1    Frank, M.E.2    Jin, W.3    Wahl, S.M.4
  • 58
    • 0026176357 scopus 로고
    • Localization of transforming growth factor-β1 in mitochondria of murine heart and liver
    • Heine, U. I. et al. Localization of transforming growth factor-β1 in mitochondria of murine heart and liver. Cell. Regul. 2, 467-477 (1991).
    • (1991) Cell. Regul. , vol.2 , pp. 467-477
    • Heine, U.I.1
  • 59
    • 0027248910 scopus 로고
    • Modulation of macrophage function by transforming growth factor beta, interleukin-4, and interleukin-10
    • Bogdan, C. & Nathan, C. Modulation of macrophage function by transforming growth factor beta, interleukin-4, and interleukin-10. Ann. NY Acad. Sci. 685, 713-739 (1993).
    • (1993) Ann. NY Acad. Sci. , vol.685 , pp. 713-739
    • Bogdan, C.1    Nathan, C.2
  • 60
    • 0028191375 scopus 로고
    • Control of nitric oxide synthase expression by transforming growth factor-β: Implications for homeostasis
    • Vodovotz, Y. & Bogdan, C. Control of nitric oxide synthase expression by transforming growth factor-β: implications for homeostasis. Prog. Growth Factor Res. 5, 341-351 (1994).
    • (1994) Prog. Growth Factor Res. , vol.5 , pp. 341-351
    • Vodovotz, Y.1    Bogdan, C.2
  • 61
    • 0030893704 scopus 로고    scopus 로고
    • Contrasting effects of TGF-β1 and TNF-α on the development of dandritic cells from progenitors in mouse bone marrow
    • Yamaguchi, Y., Tsumura, H., Miwa, M. & Inaba, K. Contrasting effects of TGF-β1 and TNF-α on the development of dandritic cells from progenitors in mouse bone marrow. Stem Cells 15, 144-153 (1997).
    • (1997) Stem Cells , vol.15 , pp. 144-153
    • Yamaguchi, Y.1    Tsumura, H.2    Miwa, M.3    Inaba, K.4
  • 62
    • 0033561648 scopus 로고    scopus 로고
    • TGF-β1 prevents the noncognate maturation of human dendritic Langerhans cells
    • Geissmann, F. et al. TGF-β1 prevents the noncognate maturation of human dendritic Langerhans cells J. Immunol. 162, 4567-4575 (1999).
    • (1999) J. Immunol. , vol.162 , pp. 4567-4575
    • Geissmann, F.1
  • 63
    • 0035838984 scopus 로고    scopus 로고
    • Dendritic cells: Specialized and regulated antigen processing machines
    • Mellman, I. & Steinman, R. M. Dendritic cells: specialized and regulated antigen processing machines. Cell 106, 255-258 (2001).
    • (2001) Cell , vol.106 , pp. 255-258
    • Mellman, I.1    Steinman, R.M.2
  • 64
    • 0033625219 scopus 로고    scopus 로고
    • TGF-β1 inhibits protracted-relapsing experimental autoimmune encephalomyelitis by activating dendritic cells
    • Jin, Y. X. et al. TGF-β1 inhibits protracted-relapsing experimental autoimmune encephalomyelitis by activating dendritic cells. J. Autoimmun. 213-220 (2000).
    • (2000) J. Autoimmun. , pp. 213-220
    • Jin, Y.X.1
  • 65
    • 0031093495 scopus 로고    scopus 로고
    • TGF-β suppresses IFN-γ induction of class II MHC gene expression by inhibiting class II transactivator messenger RNA expression
    • Lee, Y. J. et al. TGF-β suppresses IFN-γ induction of class II MHC gene expression by inhibiting class II transactivator messenger RNA expression. J. Immunol. 158, 2065-2075 (1997).
    • (1997) J. Immunol. , vol.158 , pp. 2065-2075
    • Lee, Y.J.1
  • 66
    • 0031065145 scopus 로고    scopus 로고
    • TGF-β attenuates the class II transactivator and reveals an accessory pathway of IFN-γ action
    • Nandan, D. & Reiner, N. E. TGF-β attenuates the class II transactivator and reveals an accessory pathway of IFN-γ action. J. Immunol. 158, 1095-1101 (1997).
    • (1997) J. Immunol. , vol.158 , pp. 1095-1101
    • Nandan, D.1    Reiner, N.E.2
  • 67
    • 0033697670 scopus 로고    scopus 로고
    • TGF-β receptor controls B cell responsiveness and induction of IgA in vivo
    • Cazac, B. B. & Roes, J. TGF-β receptor controls B cell responsiveness and induction of IgA in vivo. Immunity 13, 443-451 (2000).
    • (2000) Immunity , vol.13 , pp. 443-451
    • Cazac, B.B.1    Roes, J.2
  • 68
    • 0035153463 scopus 로고    scopus 로고
    • Role of transforming growth factor β in cancer
    • Pasche, B. Role of transforming growth factor β in cancer. J. Cell. Physiol. 186, 153-168 (2001).
    • (2001) J. Cell. Physiol. , vol.186 , pp. 153-168
    • Pasche, B.1
  • 69
    • 0033162687 scopus 로고    scopus 로고
    • Expression and secretion of TGF-β isoforms and expression of TGF-β-receptors I, I, and III in normal and neoplastic human breast
    • Chakravarthy, D., Green, A. R., Green, V. L., Kerin, M. J. & Speirs, V. Expression and secretion of TGF-β isoforms and expression of TGF-β-receptors I, I, and III in normal and neoplastic human breast. Int. J. Oncol. 15, 187-194 (1999).
    • (1999) Int. J. Oncol. , vol.15 , pp. 187-194
    • Chakravarthy, D.1    Green, A.R.2    Green, V.L.3    Kerin, M.J.4    Speirs, V.5
  • 70
    • 0029033765 scopus 로고
    • Transforming growth factor β secretion from primary breast cancer fibroblasts
    • van Roozendaal, C. E. et al. Transforming growth factor β secretion from primary breast cancer fibroblasts. Mol. Cell. Endocrinol. 111, 1-6 (1995).
    • (1995) Mol. Cell. Endocrinol. , vol.111 , pp. 1-6
    • Van Roozendaal, C.E.1
  • 71
    • 0031570027 scopus 로고    scopus 로고
    • +) T cells established from murine tumor-infiltrating lymphocytes
    • +) T cells established from murine tumor-infiltrating lymphocytes. J. Immunol. 158, 4846-4854 (1997).
    • (1997) J. Immunol. , vol.158 , pp. 4846-4854
    • Tamada, K.1
  • 72
    • 0033168162 scopus 로고    scopus 로고
    • Depletion of IL-10- and TGF-β-producing regulatory γδ T cells by administering a daunomycin-conjugated specific monoclonal antibody in early tumor lesions augments the activity of CTLs and NK cells
    • Seo, N., Tokura, Y., Takigawa, M. & Egawa, K. Depletion of IL-10- and TGF-β-producing regulatory γδ T cells by administering a daunomycin-conjugated specific monoclonal antibody in early tumor lesions augments the activity of CTLs and NK cells. J. Immunol. 163, 242-249 (1999).
    • (1999) J. Immunol. , vol.163 , pp. 242-249
    • Seo, N.1    Tokura, Y.2    Takigawa, M.3    Egawa, K.4
  • 73
    • 0033559577 scopus 로고    scopus 로고
    • Tumorigenicity of mouse thymoma is suppressed by soluble type II transforming growth factor β receptor therapy
    • Won, J. et al. Tumorigenicity of mouse thymoma is suppressed by soluble type II transforming growth factor β receptor therapy. Cancer Res. 59, 1273-1277 (1999).
    • (1999) Cancer Res. , vol.59 , pp. 1273-1277
    • Won, J.1
  • 74
    • 0034770605 scopus 로고    scopus 로고
    • Immune-mediated eradication of tumors through the blockade of transforming growth factor-β signaling in T cells
    • Gorelik, L. & Flavell, R. A. Immune-mediated eradication of tumors through the blockade of transforming growth factor-β signaling in T cells. Nature Med. 7, 1118-1122 (2001).
    • (2001) Nature Med. , vol.7 , pp. 1118-1122
    • Gorelik, L.1    Flavell, R.A.2
  • 75


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.