-
1
-
-
0034084162
-
Regulatory T cells in autoimmmunity
-
Shevach, E.M. Regulatory T cells in autoimmmunity. Annu. Rev. Immunol. 18, 423-449 (2000).
-
(2000)
Annu. Rev. Immunol.
, vol.18
, pp. 423-449
-
-
Shevach, E.M.1
-
2
-
-
0033738329
-
The role of different subsets of T regulatory cells in controlling autoimmunity
-
Roncarolo, M.G. & Levings, M.K. The role of different subsets of T regulatory cells in controlling autoimmunity. Curr. Opin. Immunol. 12, 676-683 (2000).
-
(2000)
Curr. Opin. Immunol.
, vol.12
, pp. 676-683
-
-
Roncarolo, M.G.1
Levings, M.K.2
-
3
-
-
0034716925
-
Regulatory T cells: Key controllers of immunologic self-tolerance
-
Sakaguchi, S. Regulatory T cells: key controllers of immunologic self-tolerance. Cell 101, 455-458 (2000).
-
(2000)
Cell
, vol.101
, pp. 455-458
-
-
Sakaguchi, S.1
-
4
-
-
0036195161
-
+ immunoregulatory T cells: Gene expression analysis reveals a functional role for the glucocorticoid-induced TNF receptor
-
+ immunoregulatory T cells: gene expression analysis reveals a functional role for the glucocorticoid-induced TNF receptor. Immunity 16, 311-323 (2002).
-
(2002)
Immunity
, vol.16
, pp. 311-323
-
-
McHugh, R.S.1
-
6
-
-
0034679560
-
+ regulatory T cells constitutively expressing cytotoxic T lymphocyte-associated antigen 4
-
+ regulatory T cells constitutively expressing cytotoxic T lymphocyte-associated antigen 4. J. Exp. Med. 192, 303-310 (2000).
-
(2000)
J. Exp. Med.
, vol.192
, pp. 303-310
-
-
Takahashi, T.1
-
7
-
-
0035801335
-
+ regulatory T cells is mediated by cell surface-bound transforming growth factor β
-
+ regulatory T cells is mediated by cell surface-bound transforming growth factor β. J. Exp. Med. 194, 629-644 (2001).
-
(2001)
J. Exp. Med.
, vol.194
, pp. 629-644
-
-
Nakamura, K.1
Kitani, A.2
Strober, W.3
-
8
-
-
0029788211
-
Autoimmune disease as a consequence of developmental abnormality of a T cell subpopulation
-
Asano, M., Toda, M., Sakaguchi, N. & Sakaguchi, S. Autoimmune disease as a consequence of developmental abnormality of a T cell subpopulation. J. Exp. Med. 184, 387-396 (1996).
-
(1996)
J. Exp. Med.
, vol.184
, pp. 387-396
-
-
Asano, M.1
Toda, M.2
Sakaguchi, N.3
Sakaguchi, S.4
-
9
-
-
0026799402
-
Targeted disruption of the mouse transforming growth factor-β1 gene results in multifocal inflammatory disease
-
Shull, M.M. et al. Targeted disruption of the mouse transforming growth factor-β1 gene results in multifocal inflammatory disease. Nature 359, 693-699 (1992).
-
(1992)
Nature
, vol.359
, pp. 693-699
-
-
Shull, M.M.1
-
10
-
-
0027531528
-
Transforming growth factor β1 null mutation in mice causes excessive inflammatory response and early death
-
Kulkarni, A.B. et al. Transforming growth factor β1 null mutation in mice causes excessive inflammatory response and early death. Proc. Natl. Acad. Sci. USA 90, 770-774 (1993).
-
(1993)
Proc. Natl. Acad. Sci. USA
, vol.90
, pp. 770-774
-
-
Kulkarni, A.B.1
-
11
-
-
0028867420
-
Loss of CTLA-4 leads to massive lymphoproliferation and fatal multiorgan tissue destruction, revealing a critical negative regulatory role of CTLA-4
-
Tivol, E.A. et al. Loss of CTLA-4 leads to massive lymphoproliferation and fatal multiorgan tissue destruction, revealing a critical negative regulatory role of CTLA-4. Immunity 3, 541-547 (1995).
-
(1995)
Immunity
, vol.3
, pp. 541-547
-
-
Tivol, E.A.1
-
12
-
-
0028791059
-
Lymphoproliferative disorders with early lethality in mice deficient in Ctla-4
-
Waterhouse, P. et al. Lymphoproliferative disorders with early lethality in mice deficient in Ctla-4. Science 270, 985-988 (1995).
-
(1995)
Science
, vol.270
, pp. 985-988
-
-
Waterhouse, P.1
-
13
-
-
0037099613
-
+ Regulatory T cells can mediate suppressor function in the absence of transforming growth factor β1 production and responsiveness
-
+ Regulatory T cells can mediate suppressor function in the absence of transforming growth factor β1 production and responsiveness. J. Exp. Med. 196, 237-246 (2002).
-
(2002)
J. Exp. Med.
, vol.196
, pp. 237-246
-
-
Piccirillo, C.A.1
-
14
-
-
0025317650
-
The scurfy mouse mutant has previously unrecognized hematological abnormalities and resembles Wiskott-Aldrich syndrome
-
Lyon, M.F., Peters, J., Glenister, P.H., Ball, S. & Wright, E. The scurfy mouse mutant has previously unrecognized hematological abnormalities and resembles Wiskott-Aldrich syndrome. Proc. Natl. Acad. Sci. USA 87, 2433-2437 (1990).
-
(1990)
Proc. Natl. Acad. Sci. USA
, vol.87
, pp. 2433-2437
-
-
Lyon, M.F.1
Peters, J.2
Glenister, P.H.3
Ball, S.4
Wright, E.5
-
15
-
-
0026178213
-
X-linked lymphoreticular disease in the scurfy (sf) mutant mouse
-
Godfrey, V.L., Wilkinson, J.E. & Russell, L.B. X-linked lymphoreticular disease in the scurfy (sf) mutant mouse. Am. J. Pathol. 138, 1379-1387 (1991).
-
(1991)
Am. J. Pathol.
, vol.138
, pp. 1379-1387
-
-
Godfrey, V.L.1
Wilkinson, J.E.2
Russell, L.B.3
-
16
-
-
0026043866
-
Fatal lymphoreticular disease in the scurfy (sf) mouse requires T cells chat mature in a sf fthymic environment: Potential model for thymic education
-
Godfrey, V., Wilkinson, J., Rinchik, E. & Russell, L. Fatal lymphoreticular disease in the scurfy (sf) mouse requires T cells chat mature in a sf fthymic environment: potential model for thymic education. Proc. Natl. Acad. Sci. USA 88, 5528-5532 (1991).
-
(1991)
Proc. Natl. Acad. Sci. USA
, vol.88
, pp. 5528-5532
-
-
Godfrey, V.1
Wilkinson, J.2
Rinchik, E.3
Russell, L.4
-
17
-
-
0028122921
-
Transplantation of T cell-mediated, lymphoreticular disease from the scurfy (sf) mouse
-
Godfrey, V.L., Rouse, B.T. & Wilkinson, J.E. Transplantation of T cell-mediated, lymphoreticular disease from the scurfy (sf) mouse. Am. J. Pathol. 145, 281-286 (1994).
-
(1994)
Am. J. Pathol.
, vol.145
, pp. 281-286
-
-
Godfrey, V.L.1
Rouse, B.T.2
Wilkinson, J.E.3
-
18
-
-
0030069074
-
Disease in the scurfy (sf) mouse is associated with overexpression of cytokine genes
-
Kanangat, S. et al. Disease in the scurfy (sf) mouse is associated with overexpression of cytokine genes. Eur. J. Immunol. 26, 161-165 (1996).
-
(1996)
Eur. J. Immunol.
, vol.26
, pp. 161-165
-
-
Kanangat, S.1
-
19
-
-
0028171297
-
− T cells are the effector cells in disease pathogenesis in the scurly (sf) mouse
-
− T cells are the effector cells in disease pathogenesis in the scurly (sf) mouse. J. Immunol. 153, 3764-3774 (1994).
-
(1994)
J. Immunol.
, vol.153
, pp. 3764-3774
-
-
Blair, P.J.1
-
20
-
-
0035162560
-
Disruption of a new forkhead/winged-helix protein, scurfin, results in the fatal lymphoproliferative disorder of the scurfy mouse
-
Brunkow, M.E. et al. Disruption of a new forkhead/winged-helix protein, scurfin, results in the fatal lymphoproliferative disorder of the scurfy mouse. Nat. Genet. 27, 68-73 (2001).
-
(2001)
Nat. Genet.
, vol.27
, pp. 68-73
-
-
Brunkow, M.E.1
-
21
-
-
0034526617
-
JM2, encoding a fork head-related protein, is mutated in X-linked autoimmunity-allergic disregulation syndrome
-
Chatila, T.A. et al. JM2, encoding a fork head-related protein, is mutated in X-linked autoimmunity-allergic disregulation syndrome. J. Clin. Invest. 106, R75-R81 (2000).
-
(2000)
J. Clin. Invest.
, vol.106
, pp. R75-R81
-
-
Chatila, T.A.1
-
22
-
-
0035163909
-
X-linked neonatal diabetes mellitus, enteropathy and endocrinopathy syndrome is the human equivalent of mouse scurfy
-
Wildin, R.S. et al. X-linked neonatal diabetes mellitus, enteropathy and endocrinopathy syndrome is the human equivalent of mouse scurfy. Nat. Genet. 27, 18-20 (2001).
-
(2001)
Nat. Genet.
, vol.27
, pp. 18-20
-
-
Wildin, R.S.1
-
23
-
-
0035167967
-
The immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome (IPEX) is caused by mutations of FOXP3
-
Bennett, C.L. et al. The immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome (IPEX) is caused by mutations of FOXP3. Nat. Genet. 27, 20-21 (2001).
-
(2001)
Nat. Genet.
, vol.27
, pp. 20-21
-
-
Bennett, C.L.1
-
24
-
-
0035576221
-
The amount of scurfin protein determines peripheral T cell number and responsiveness
-
Khattri, R. et al. The amount of scurfin protein determines peripheral T cell number and responsiveness. J. Immunol. 167, 6312-6320 (2001).
-
(2001)
J. Immunol.
, vol.167
, pp. 6312-6320
-
-
Khattri, R.1
-
25
-
-
0033105648
-
Cellular and molecular characterization of the scurfy mouse mutant
-
Clark, L.B. et al. Cellular and molecular characterization of the scurfy mouse mutant. J. Immunol. 162, 2546-2554 (1999).
-
(1999)
J. Immunol.
, vol.162
, pp. 2546-2554
-
-
Clark, L.B.1
-
26
-
-
0030740248
-
Thymocyte development is normal in CTLA-4-deficient mice
-
Chambers, C.A., Cado, D., Truong, T. & Allison, J.P. Thymocyte development is normal in CTLA-4-deficient mice. Proc. Natl. Acad. Sci. USA 94, 9296-9301 (1997).
-
(1997)
Proc. Natl. Acad. Sci. USA
, vol.94
, pp. 9296-9301
-
-
Chambers, C.A.1
Cado, D.2
Truong, T.3
Allison, J.P.4
-
27
-
-
0037097594
-
The lymphoproliferative defect in CTLA-4-deficient mice is ameliorated by an inhibitory NK cell receptor
-
Chambers, C.A. et al. The lymphoproliferative defect in CTLA-4-deficient mice is ameliorated by an inhibitory NK cell receptor. Blood 99, 4509-4516 (2002).
-
(2002)
Blood
, vol.99
, pp. 4509-4516
-
-
Chambers, C.A.1
-
28
-
-
0035813231
-
Scurfin (foxp3) acts as a repressor of transcription and regulates T cell activation
-
Schubert, L.A., Jeffery E., Zhang, Y., Ramsdell, F. & Ziegler, S.F. Scurfin (foxp3) acts as a repressor of transcription and regulates T cell activation. J. Biol. Chem. 276, 37672-37679 (2001).
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 37672-37679
-
-
Schubert, L.A.1
Jeffery, E.2
Zhang, Y.3
Ramsdell, F.4
Ziegler, S.F.5
-
29
-
-
0033136302
-
+ naturally anergic and suppressive T cells as a key function of the thymus in maintaining immunologic self-tolerance
-
+ naturally anergic and suppressive T cells as a key function of the thymus in maintaining immunologic self-tolerance. J. Immunol. 162, 5317-5326 (1999).
-
(1999)
J. Immunol.
, vol.162
, pp. 5317-5326
-
-
Itoh, M.1
-
31
-
-
0035320679
-
+ regulatory T cells induced by an agonist self-peptide
-
+ regulatory T cells induced by an agonist self-peptide. Nat. Immunol. 2, 301-306 (2001).
-
(2001)
Nat. Immunol.
, vol.2
, pp. 301-306
-
-
Jordan, M.S.1
-
33
-
-
0030938918
-
A targeted mutation at the T-cell receptor α/δ locus impairs T-cell development and reveals the presence of the nearby antiapoptosis gene Dadl
-
Hong, N.A. et al. A targeted mutation at the T-cell receptor α/δ locus impairs T-cell development and reveals the presence of the nearby antiapoptosis gene Dadl. Mol. Cell. Biol. 17, 2151-2157
-
(1997)
Mol. Cell. Biol.
, vol.17
, pp. 2151-2157
-
-
Hong, N.A.1
|