Stimulation of CD25+CD4+ regulatory T cells through GITR breaks immunological self-tolerance

Nature Immunology

Volumn 3, Issue 2, 2002, Pages 135-142

  Shimizu, Jun ^a   Yamazaki, Sayuri ^b   Takahashi, Takeshi ^b   Ishida, Yasumasa ^c   Sakaguchi, Shimon ^b  

^a TOKYO METROPOLITAN INSTITUTE OF GERONTOLOGY   (Japan)

^b KYOTO UNIVERSITY   (Japan)

^c NARA INSTITUTE OF SCIENCE AND TECHNOLOGY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CD4 ANTIGEN; CD8 ANTIGEN; GLUCOCORTICOID INDUCED TUMOR NECROSIS FACTOR RECEPTOR FAMILY RELATED GENE; INTERLEUKIN 2 RECEPTOR; MONOCLONAL ANTIBODY; NERVE GROWTH FACTOR RECEPTOR; TUMOR NECROSIS FACTOR RECEPTOR; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; AUTOIMMUNE DISEASE; CONTROLLED STUDY; FEMALE; GENE EXPRESSION; GENE TARGETING; HUMAN; HUMAN CELL; IMMUNE DEFICIENCY; IMMUNOLOGICAL TOLERANCE; IMMUNOREGULATION; LYMPHOCYTE ACTIVATION; MOUSE; MULTIGENE FAMILY; NONHUMAN; NONVIRAL GENE DELIVERY SYSTEM; PRIORITY JOURNAL; RAT; T LYMPHOCYTE; THYMOCYTE;

ANIMALS; ANTIGENS, CD4; AUTOIMMUNE DISEASES; CD4-POSITIVE T-LYMPHOCYTES; DIMERIZATION; GLYCOPROTEINS; IMMUNE TOLERANCE; LYMPH NODES; MICE; MICE, INBRED BALB C; RATS; RATS, WISTAR; RECEPTORS, INTERLEUKIN-2; RECEPTORS, NERVE GROWTH FACTOR; RECEPTORS, TUMOR NECROSIS FACTOR; SIGNAL TRANSDUCTION; SPLEEN; T-LYMPHOCYTE SUBSETS;

EID: 0036170938     PISSN: 15292908     EISSN: None     Source Type: Journal    
DOI: 10.1038/ni759     Document Type: Article

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