Haplotype associated with low interleukin-10 production in patients with severe asthma

Lancet

Volumn 352, Issue 9122, 1998, Pages 113-

  Lim, Sam ^b   Crawley, Esther ^b   Woo, Patricia ^b   Barnes, Peter J ^a  

^a IMPERIAL COLLEGE SCHOOL OF MEDICINE   (United Kingdom)

^b ROYAL FREE AND UNIVERSITY COLLEGE MEDICAL SCHOOL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

INTERLEUKIN 10; MESSENGER RNA;

ARTICLE; ASTHMA; CONTROLLED STUDY; DISEASE SEVERITY; GENE EXPRESSION; HAPLOTYPE; HUMAN; MAJOR CLINICAL STUDY; PRIORITY JOURNAL;

EID: 13144279268     PISSN: 01406736     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0140-6736(98)85018-6     Document Type: Article

References (5)

1. Moore KW, O'Garra A, de-Waal-Malefyt R, Vieira P, Mosmann TR. Interleukin-10. Annu Rev Immunol 1993; 11: 165-90.
2. John M, Lim S, Seybold J, et al. Inhaled corticosteroids increase IL-10 but reduce MIP-1α, CM-CSF and INF γ release from alveolor macrophages in asthma. Am J Respir Crit Care Med 1998; 157: 259-62.
3. Turner DM, Williams DM, Sankaran D, Lazarus M, Sinnott PJ, Hutchinson IV. An investigation of polymorphism in the interleukin-10 gene promoter. Eur J Immunogenet 1997; 24: 1-8.
4. Kube D, Platzer C, von Knethen A, Straub H, Bohlen Hafner M, Tesch H. Isolation of the human interleukin 10 promoter. Characterization of the promoter activity in burkitts's lymphoma cell lines. Cytokine 1996; 7: 1-7.
5. Hajeer AH, Lazarus M, Turner D, et al. IL-10 gene promotes polymorphisms in rheumatoid arthritis. Scand J Rheumatol 1998; 27: 142-45.