메뉴 건너뛰기




Volumn 2, Issue 9, 2001, Pages 816-822

Regulatory T cells in the control of immune pathology

Author keywords

[No Author keywords available]

Indexed keywords

ANTIGEN; AUTOANTIGEN; CYTOKINE;

EID: 0035554676     PISSN: 15292908     EISSN: None     Source Type: Journal    
DOI: 10.1038/ni0901-816     Document Type: Review
Times cited : (1044)

References (112)
  • 6
    • 0027509812 scopus 로고
    • Evidence that the T cell repertoire of normal rats contains cells with the potential to cause diabetes. Characterization of the CD4' T cell subset that inhibits this autoimmune potential
    • (1993) J. Exp. Med , vol.177 , pp. 627-636
    • Fowell, D.1    Mason, D.2
  • 10
    • 0032171644 scopus 로고    scopus 로고
    • A very high level of crossreactivity is an essential feature of the T-cell receptor
    • (1998) Immunol. Today , vol.19 , pp. 395-404
    • Mason, D.1
  • 14
    • 0030975532 scopus 로고    scopus 로고
    • Antigen localisation regulates immune responses in a dose- and time- dependent fashion: A geographical view of immune reactivity
    • (1997) Immunol. Rev , vol.156 , pp. 199-209
    • Zinkernagel, R.M.1
  • 16
    • 0029659049 scopus 로고    scopus 로고
    • Evidence for a thymus-dependent form of tolerance that is not based on elimination or anergy of reactive T cells
    • (1996) Immunol. Rev , vol.149 , pp. 35-53
    • Le Douarin, N.1
  • 20
    • 0032538820 scopus 로고    scopus 로고
    • + T cells prevent spontaneous experimental autoimmune encephalomyelitis in anti-myelin basic protein T cell receptor transgenic mice
    • (1998) J. Exp. Med , vol.188 , pp. 1875-1882
    • Van de Keere, F.1    Tonegawa, S.2
  • 21
    • 0023161556 scopus 로고
    • + helper/inducer T lymphocytes prevent spontaneous diabetes in the BB/W rat
    • (1987) Diabetologia , vol.30 , pp. 22-26
    • Mordes, J.P.1
  • 25
    • 0031647622 scopus 로고    scopus 로고
    • + naturally anergic and suppressive T cells: Induction of autoimmune disease by breaking their anergic/suppressive state
    • (1998) Int. Immunol , vol.10 , pp. 1969-1980
    • Takahashi, T.1
  • 26
    • 0031821875 scopus 로고    scopus 로고
    • + Immunoregulatory T cells suppress polyclonal T cell activation in vitro by inhibiting interleukin 2 production
    • (1998) J. Exp. Med , vol.188 , pp. 287-296
    • Thornton, A.E.1    Shevach, E.M.2
  • 28
    • 0033682056 scopus 로고    scopus 로고
    • + immunoregulatory T cells that control autoimmune diabetes
    • (2000) Immunity , vol.12 , pp. 431-440
    • Salomon, B.1
  • 29
    • 0034679560 scopus 로고    scopus 로고
    • + regulatory T cells constitutively expressing cytotoxic T lymphocyte-associated antigen 4
    • (2000) J. Exp. Med , vol.192 , pp. 303-310
    • Takahashi, T.1
  • 32
    • 0035869432 scopus 로고    scopus 로고
    • IL-10 is required for regulatory T cells to mediate tolerance to alloantigens in vivo
    • (2001) J. Immunol , vol.166 , pp. 3789-3796
    • Hara, M.1
  • 36
    • 0035284804 scopus 로고    scopus 로고
    • + T cells regulate the expansion of peripheral CD4 T cells through the production of IL-10
    • (2001) J. Immunol , vol.166 , pp. 3008-3018
    • Annacker, O.1
  • 37
    • 0033136302 scopus 로고    scopus 로고
    • + naturally anergic and suppressive T cells as a key function of the thymus in maintaining immunologic self-tolerance
    • (1999) J. Immunol , vol.162 , pp. 5317-5326
    • Itoh, M.1
  • 39
    • 0035062581 scopus 로고    scopus 로고
    • + T cells: A highly differentiated and apoptosis-prone population
    • (2001) Eur. J. Immunol , vol.31 , pp. 1122-1131
    • Taams, L.S.1
  • 42
    • 0035806290 scopus 로고    scopus 로고
    • + T cells with regulatory properties isolated from peripheral blood
    • (2001) J. Exp. Med , vol.193 , pp. 1285-1294
    • Jonuleit, H.1
  • 44
    • 0023143676 scopus 로고
    • Antigen presentation by chemically modified splenocytes induces antigen- specific T cell unresponsiveness in vitro and in vivo
    • (1987) J. Exp. Med , vol.165 , pp. 302-319
    • Jenkins, M.K.1    Schwartz, R.H.2
  • 45
  • 46
    • 0031669999 scopus 로고    scopus 로고
    • Anergic T cells actively suppress T cell responses via the antigen- presenting cell
    • (1998) Eur. J. Immunol , vol.28 , pp. 2902-2912
    • Taams, L.S.1
  • 47
    • 0034254754 scopus 로고    scopus 로고
    • Anergic T cells inhibit the antigen-presenting function of dendritic cells
    • (2000) J. Immunol , vol.165 , pp. 1175-1181
    • Vendetti, S.1
  • 48
    • 0031964338 scopus 로고    scopus 로고
    • Interleukin 10 secretion and impaired effector function of major histocompatibility complex class II-restricted T cells anergized in vivo
    • (1998) J. Exp. Med , vol.187 , pp. 177-183
    • Buer, J.1
  • 49
    • 0030636560 scopus 로고    scopus 로고
    • Immunoregulatory role of IL-10 during superantigen-induced hyporesponsiveness in vivo
    • (1997) J. Immunol , vol.158 , pp. 180-186
    • Sundstedt, A.1
  • 51
    • 0030704726 scopus 로고    scopus 로고
    • + T-cell subset inhibits antigen-specific T-cell responses and prevents colitis
    • (1997) Nature , vol.389 , pp. 737-742
    • Groux, H.1
  • 54
    • 0029995799 scopus 로고    scopus 로고
    • Experimental granulomatous colitis in mice is abrogated by induction of TGF-β-mediated oral tolerance
    • (1996) J. Exp. Med , vol.183 , pp. 2605-2616
    • Neurath, M.F.1
  • 55
    • 0030847054 scopus 로고    scopus 로고
    • Oral tolerance: Immune mechanisms and treatment of autoimmune diseases
    • (1997) Immunol. Today , vol.18 , pp. 335-343
    • Weiner, H.L.1
  • 59
    • 0033571454 scopus 로고    scopus 로고
    • + CD45RB low-density cells from untreated mice prevent acute allograft rejection
    • (1999) J. Immunol , vol.163 , pp. 5353-5357
    • Davies, J.D.1
  • 63
    • 0035180067 scopus 로고    scopus 로고
    • Control of intestinal inflammation by regulatory T cells
    • (in the press)
    • (2001) Immunol. Rev , vol.182
    • Singh, B.1
  • 67
    • 0033064551 scopus 로고    scopus 로고
    • Post-thymectomy autoimmune gastritis: Fine specificity and pathogenicity of anti-H/K ATPase-reactive T cells
    • (1999) Eur. J. Immunol , vol.29 , pp. 669-677
    • Suri-Payer, E.1
  • 68
    • 0035164360 scopus 로고    scopus 로고
    • Increased T cell autoreactivity in the absence of CD40-CD40 ligand interactions: A role of CD40 in regulatory T cell development
    • (2001) J. Immunol , vol.166 , pp. 353-360
    • Kumanogoh, A.1
  • 69
    • 0033853625 scopus 로고    scopus 로고
    • + T cells as a functionally and phenotypically distinct immunoregulatory T cell subpopulation
    • (2000) Int. Immunol , vol.12 , pp. 1145-1155
    • Kuniyasu, Y.1
  • 71
    • 0029586031 scopus 로고
    • Tolerance exists towards resident intestinal flora but is broken in active inflammatory bowel disease (IBD)
    • (1995) Clin. Exp. Immunol , vol.102 , pp. 448-455
    • Duchmann, R.1
  • 73
    • 0028103905 scopus 로고
    • Tissue-specific suppressor T cells involved in self-tolerance are activated extrathymically by self-antigens
    • (1994) Immunology , vol.82 , pp. 365-369
    • Taguchi, O.1
  • 74
    • 0029835613 scopus 로고    scopus 로고
    • Establishment of tissue-specific tolerance is driven by regulatory T cells selected by thymic epithelium
    • (1996) Eur. J. Immunol , vol.26 , pp. 1807-1815
    • Modigliani, Y.1
  • 75
    • 0035399985 scopus 로고    scopus 로고
    • + T cells with immunoregulatory potential in vivo following induction of peripheral tolerance with intravenous or oral antigen
    • (2001) J. Immunol , vol.167 , pp. 188-195
    • Thorstenson, K.M.1    Khoruts, A.2
  • 76
    • 0032033419 scopus 로고    scopus 로고
    • Cytokines induce the development of functionally heterogeneous T helper cell subsets
    • (1998) Immunity , vol.8 , pp. 275-283
    • O'Garra, A.1
  • 85
    • 0026607155 scopus 로고
    • IL-10 inhibits mitogen-induced T cell proliferation by selectively inhibiting macrophage costimulatory function
    • (1992) J. Immunol , vol.148 , pp. 3133-3139
    • Ding, L.1    Shevach, E.M.2
  • 86
    • 0025763807 scopus 로고
    • IL-10 acts on the antigen-presenting cell to inhibit cytokine production by Th I cells
    • (1991) J. Immunol , vol.146 , pp. 3444-3451
    • Florentino, D.F.1
  • 88
    • 0034600789 scopus 로고    scopus 로고
    • Treatment of experimental (Trinitrobenzene sulfonic acid) colitis by intranasal administration of transforming growth factor (TGF)-β1 plasmid: TGF-β1-mediated suppression of T helper cell type I response occurs by interleukin (IL)-10 ind
    • (2000) J. Exp. Med , vol.192 , pp. 41-52
    • Kitani, A.1
  • 90
    • 0034131557 scopus 로고    scopus 로고
    • Abrogation of TGFβ signaling in T cells leads to spontaneous T cell differentiation and autoimmune disease
    • (2000) Immunity , vol.12 , pp. 171-181
    • Gorelik, L.1    Flavell, R.A.2
  • 92
    • 0033034365 scopus 로고    scopus 로고
    • Enhanced Th 1 activity and development of chronic enterocolitis in mice devoid of Stat3 in macrophages and neutrophils
    • (1999) Immunity , vol.10 , pp. 39-49
    • Takeda, K.1
  • 100
    • 0035337241 scopus 로고    scopus 로고
    • CD134L expression on dendritic cells in the mesenteric lymph nodes drives colitis in T cell-restored scid mice
    • (2001) J. Immunol , vol.166 , pp. 6972-6981
    • Malmstrom, V.1
  • 106
    • 3543053363 scopus 로고    scopus 로고
    • 5 and CD36, and cross-present antigens to cytotoxic T lymphocytes
    • (1998) J. Exp. Med , vol.188 , pp. 1359-1368
    • Albert, M.L.1
  • 107
    • 0034614897 scopus 로고    scopus 로고
    • Consequences of cell death: Exposure to necrotic tumor cells, but not primary tissue cells or apoptotic cells, induces the maturation of immunostimulatory dendritic cells
    • (2000) J. Exp. Med , vol.191 , pp. 423-434
    • Sauter, B.1
  • 108
    • 0029812040 scopus 로고    scopus 로고
    • Constitutive class I-restricted exogenous presentation of self antigens in vivo
    • (1996) J. Exp. Med , vol.184 , pp. 923-930
    • Kurts, C.1
  • 110
    • 0032543225 scopus 로고    scopus 로고
    • + T cell tolerance to parenchymal self-antigens requires presentation by bone marrow-derived antigen-presenting cells
    • (1998) J. Exp. Med , vol.187 , pp. 1555-1564
    • Adler, A.J.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.