CD38+ CD45RB(low) CD4+ T cells: A population of T cells with immune regulatory activities in vitro

European Journal of Immunology

Volumn 28, Issue 11, 1998, Pages 3435-3447

  Read, Simon ^a   Mauze, Smita ^b   Asseman, Chrystelle ^a   Bean, Andrew ^b   Coffman, Robert ^b   Powrie, Fiona ^a  

^a UNIVERSITY OF OXFORD   (United Kingdom)

^b MERCK RESEARCH LABORATORIES   (United States)

Author keywords

CD4+ T cell subset; Immune regulation; Regulatory T cell

Indexed keywords

ANTIBODY; CD38 ANTIGEN; CD4 ANTIGEN; CD45 ANTIGEN; CYTOKINE;

ANIMAL CELL; ARTICLE; CYTOKINE RELEASE; IMMUNOREGULATION; LYMPHOCYTE PROLIFERATION; MEMORY CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; T LYMPHOCYTE ACTIVATION; T LYMPHOCYTE SUBPOPULATION;

ADP-RIBOSYL CYCLASE; ANIMALS; ANTIGENS, CD; ANTIGENS, CD38; ANTIGENS, CD45; ANTIGENS, DIFFERENTIATION; CD4-POSITIVE T-LYMPHOCYTES; CELL COMMUNICATION; INTERLEUKIN-10; INTERLEUKIN-2; INTERLEUKIN-4; LYMPHOCYTE ACTIVATION; MEMBRANE GLYCOPROTEINS; MICE; MICE, INBRED BALB C; NAD+ NUCLEOSIDASE; RECEPTORS, ANTIGEN, T-CELL; T-LYMPHOCYTE SUBSETS; T-LYMPHOCYTES, REGULATORY;

EID: 0031739410     PISSN: 00142980     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1521-4141(199811)28:11<3435::AID-IMMU3435>3.0.CO;2-P     Document Type: Article

References (42)

1. Thomas, M. L., The leukocyte common antigen family. Annu. Rev. Immunol. 1989. 7: 339-369.
2. Birkeland, M. L., Metlay, J., Sanders, V. M., Fernandez-Botran, R., Vitetta, E. S., Steinman, R. M. and Pure, E., Epitopes on CD45R [T200] molecules define differentiation antigens on murine B and T lymphocytes. J. Mol. Cell, Immunol. 1988. 4: 71-85.
3. Bottomry, K., Luqman, M., Greenbaum, L., Carding, S., West, J., Pasqualini, T. and Murphy, D. B., A monoclonal antibody to murine CD45R distinguishes CD4 T cell population that produce different cytokines. Eur. J. Immunol. 1989. 19: 617-623.
4. Birkeland, M. L., Johnson, P., Trowbridge, I. S. and Pure, E., Changes in CD45 isoform expression accompany antigen-induced murine T-cell activation. Proc. Natl. Acad. Sci. USA 1989. 86: 6734-6738.
5. + T cells. J. Immunol. 1990. 144: 3288-3295.
6. + T cells, Immunol. Today 1988. 9: 274-277.
7. Beverley, P. C., Human T cell subsets. Immunol. Lett. 1987. 14: 263-267.
8. + T cells are important for the balance between protective and pathogenic cell-mediated immunity. J. Exp. Med. 1994. 179: 589-600.
9. + Iymphocytes: mouse strain polymorphism and different responses to distinct antigens. Cell. Immunol. 1993. 148: 269-282.
10. Bunce, C. and Bell, E. B., CD45RC isoforms define two types of CD4 memory T cells, one of which depends on persisting antigen. J. Exp. Med. 1997. 185: 767-776.
11. + T cells induce or protect from chronic intestinal inflammation in C. B-17scid mice. Int. Immunol. 1993. 5: 1461-1471.
12. + T cells. J. Exp. Med. 1993. 178: 237-244.
13. + T cells. J. Exp. Med. 1996. 183: 2669-2674.
14. Santos-Argumedo, L., Teixeira, C., Preece, G., Kirkham, P. A. and Parkhouse, R. M., A B lymphocyte surface molecule mediating activation and protection from apoptosis via calcium channels. J. Immunol. 1993. 151: 319-3130.
15. Harada, N., Santos-Argumedo, L., Chang, R. et al., Expression cloning of a cDNA encoding a novel murine B cell activation marker. Homology to human CD38. J. Immunol. 1993. 151: 3111-3118.
16. Bean, A. G., Godfrey, D. I., Ferlin, W. G., Santos-Argumedo, L., Parkhouse, M. E., Howard, M. C. and Zlotnik, A., CD38 expression on mouse T cells: CD38 defines functionally distinct subsets of alpha beta TCR + CD4-CD8-thymocytes. Int. Immunol. 1995. 7: 213-221.
17. Locksley, R. M. and Scott, P., Helper T-cell subsets in mouse leishmaniasis: induction, expansion and effector function, Immunol. Today 1991. 12: 58-61.
18. Schwartz, R. H., A cell culture model for T lymphocyte clonal anergy. Science 1990. 248: 1349-1356.
19. Hercend, T., Ritz, J., Schlossman, S. F. and Reinherz, E. L., Comparative expression of T9, T10, and Ia anti-gens on activated human T cell subsets. Hum. Immunol. 1981. 3: 247-259.
20. Howard, M., Grimaldi, J. C., Bazan, J. F., Lund, F. E., Santos-Argumedo, L., Parkhouse, R. M., Walsetz, T. F. and Lee, H. C., Formation and hydrolysis of cyclic ADP-ribose catalyzed by lymphocyte antigen CD38. Science 1993. 262: 1056-1059.
21. Shubinsky, G. and Schlesinger, M., The CD38 lymphocyte differentiation marker: new insight into its ectoenzymatic activity and its role as a signal transducer, Immunity 1997. 7: 315-324.
22. Zubiaur, M., Izquierdo, M., Terhorst, C., Malavasi, F. and Sancho, J., CD38 ligation results in activation of the Raf-1/mitogen-activated protein kinase and the CD3-zeta/zeta-associated protein-70 signaling pathways in Jurkat T lymphocytes. J. Immunol. 1997. 159: 193-205.
23. Malavasi, F., Funaro, A., Roggero, S., Horenstein, A., Calosso, L. and Mehta, K., Human CD38: a glycoprotein in search of a function, Immunol. Today 1994. 15: 95-97.
24. + cells in the rat. Am. J. Pathol. 1996. 148: 2043-2056.
25. Koch-Nolte, F., Klein, J., Hollmann, C., Kuhl, M., Haag, F., Gaskins, H. R., Leiter, E. and Thiele, H. G., Defects in the structure and expression of the genes for the T cell marker Rt6 in NZW and (NZB × NZW)F1 mice. Int. Immunol. 1995. 7: 883-890.
26. Farber, D. L., Luqman, M., Acuto, O. and Bottomly, K., Control of memory CD4 T cell activation: MHC class II molecules on APCs and CD4 ligation inhibit memory but not naive CD4 T cells. Immunity 1995. 2: 249-259.
27. Lee, W. T. and Vitetta, E. S., Memory T cells are anergic to the superantigen staphylococcal enterotoxin B. J. Exp. Med. 1992. 176: 575-579.
28. Hamel, M. E., Eynon, E. E., Savelkoul, H. F., van Oudenaren, A. and Kruisbeek, A. M., Activation and reactivation potential of T cells responding to staphylococcal enterotoxin B. Int. Immunol. 1995. 7: 1065-1077.
29. Morahan, G., Hoffmann, M. W. and Miller, J. F., A non-deletional mechanism of peripheral tolerance in T-cell receptor transgenic mice. Proc. Natl. Acad. Sci. USA 1991. 88: 11421-11425.
30. Lamb, J. R., Skidmore, B. J., Green, N., Chiller, J. M. and Feldmann, M., Induction of tolerance in influenza virus-immune T lymphocyte clones with synthetic peptides of influenza hemagglutinin. J. Exp. Med. 1983. 157: 1434-1447.
31. Jenkins, M. K., Pardoll, D. M., Mizuguchi, J., Quill, H. and Schwartz, R. H., T-cell unresponsiveness in vivo and in vitro: fine specificity of induction and molecular characterization of the unresponsive state, Immunol. Rev. 1987. 95: 113-135.
32. + T cells by staphylococcal enterotoxin B. J. Exp. Med. 1990. 172: 1091-1100.
33. + T lymphocytes on immunizing Mls-1b mice with Mls-1a expressing cells. Nature 1989. 339: 541-544.
34. Perez, V. L., Van Parijs, L., Biuckians, A., Zheng, X. X., Strom, T. B. and Abbas, A. K., Induction of peripheral T cell tolerance in vivo requires CTLA-4 engagement. Immunity 1997. 6: 411-417.
35. Kearney, E. R., Pape, K. A., Loh, D. Y. and Jenkins, M. K., Visualization of peptide-specific T cell immunity and peripheral tolerance induction in vivo. Immunity 1994. 1: 327-339.
36. Lombardi, G., Sidhu, S., Batchelor, R. and Lechler, R., Anergic T cells as suppressor cells in vitro. Science 1994. 264: 1587-1589.
37. + T-cell subset inhibits antigen-specific T-cell responses and prevents colitis. Nature 1997. 389: 737-742.
38. + T cells in vitro. J. Virol. 1996. 70: 7540-7548.
39. Murphy, K. M., Heimberger, A. B. and Loh, D. Y., Induction by antigen of intrathymic apoptosis of CD4+CDS+ TCRIo thymocytes in vivo. Science 1990. 250: 1720-1723.
40. Marrack, P., Shimonkevitz, R., Hannum, C., Haskins, K. and Kappler, J., The major histocompatibility complex-restricted antigen receptor on T cells. IV. An antiidiotypic antibody predicts both antigen and Ispecificity. J. Exp. Med. 1983. 158: 1635-1646.
41. Coffman, R. L., Surface antigen expression and immunoglobulin gene rearrangement during mouse Pre-B cell development, Immunol. Rev. 1982. 69: 5-23.
42. Abrams, J. S., Roncarolo, M. G., Yssel, H., Andersson, U., Gleich, G. J. and Silver, J. E., Strategies of anti-cytokine monoclonal antibody development: immunoassay of IL-10 and IL-5 in clinical samples, Immunol. Rev. 1992. 127: 5-24.